LOCUS       NM_053186               5193 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cyclin M3 (Cnnm3), transcript variant 1, mRNA.
ACCESSION   NM_053186
VERSION     NM_053186.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5193)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5193)
  AUTHORS   Hardy,S., Uetani,N., Wong,N., Kostantin,E., Labbe,D.P., Begin,L.R.,
            Mes-Masson,A., Miranda-Saavedra,D. and Tremblay,M.L.
  TITLE     The protein tyrosine phosphatase PRL-2 interacts with the magnesium
            transporter CNNM3 to promote oncogenesis
  JOURNAL   Oncogene 34 (8), 986-995 (2015)
   PUBMED   24632616
  REMARK    GeneRIF: Oncogenic PRL-2 controls tumor growth by modulating
            intracellular magnesium levels through binding with the CNNM3
            magnesium transporter.
REFERENCE   3  (bases 1 to 5193)
  AUTHORS   Wang,C.Y., Yang,P., Shi,J.D., Purohit,S., Guo,D., An,H., Gu,J.G.,
            Ling,J., Dong,Z. and She,J.X.
  TITLE     Molecular cloning and characterization of the mouse Acdp gene
            family
  JOURNAL   BMC Genomics 5 (1), 7 (2004)
   PUBMED   14723793
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084391.1, BC080275.1 and AF216964.1.
            
            On Sep 13, 2016 this sequence version replaced NM_053186.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF216964.1, BC132285.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-582               AC084391.1         85058-85639         c
            583-940             BC080275.1         1-358
            941-2640            AF216964.1         1-1700
            2641-5193           BC080275.1         2158-4710
FEATURES             Location/Qualifiers
     source          1..5193
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 15.3 cM"
     gene            1..5193
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /note="cyclin M3"
                     /db_xref="GeneID:94218"
                     /db_xref="MGI:MGI:2151055"
     exon            1..1287
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1431
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1581
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1751
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1848
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..1982
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            1983..2121
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     exon            2122..5193
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4144..4149
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /note="hexamer: AATAAA"
     polyA_site      4172
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /note="major polyA site"
     regulatory      4994..4999
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /note="hexamer: ATTAAA"
     polyA_site      5014
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
     regulatory      5173..5178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
                     /note="hexamer: ATTAAA"
     polyA_site      5193
                     /gene="Cnnm3"
                     /gene_synonym="Acdp3; Clp3; mACDP3"
ORIGIN      
        1 gagtggggta ggctgcgccc gaggcccaga aggggtagca ggccatggcg gcggctgctg
       61 cggctgtggt gggttggttg ggctgggtgc ttgccgcgtt ctgtctgggc agcaccgcag
      121 gggaggcggc gccggcgccg ggcgcgggac tgctgaactt ctgcacggaa gaggacagcg
      181 caccgggcgc gggctccctg cgcggaaggg cagcgccaga ggccactttg tgcttgcgac
      241 tcttctgctc cggcttggcc aacagctcct ggacctgggt agccgccgag ggcgcaggct
      301 gcccggaggg cggacgggcc acggagcccg aggaggcggc cgccccgacg ggcgagtggc
      361 gcgcgctgct gcgcctgcgc gccgaggccg gccacccgcg ctccgcgctg ctggcggtgc
      421 gcgtggagcc gggtggtggg gccgcggagg aggcggcgcc gccctgggcg ctggggctgg
      481 gggcggccgg gctgctggcc ctggcggcgg tggcgcgcgg cctgcagctg agcgcgctgg
      541 cgctggcgcc ggccgaggtg caggtgctgc gcgagagcgg ctcggaggcg gagcgcgcgg
      601 cggcgcggcg cctggaaccc gcgcggcgct gggccggctg cgccctgggc gcgctgctgc
      661 ttctggccag cctggcgcag gcggcactgg ccgtgctgct gtacggggcg gcgggccagc
      721 gcgccgtgcc cgccgtgctg ggttgcgcgg ggctggtgtt cctggtgggt gaggtgctgc
      781 cggccgccgt gagcggacgc tgggcgctgg cgctggcgcc gcgcgcgttg ggcctcagcc
      841 gcctggcggt gctgctcacc ttgcccgtgg cgctgccggt cgggcagctg ctggagctgg
      901 cagcgcggcc ggggcgtctg cgggagcgcg tgctggagct ggcgcgcggc ggcggcgacc
      961 cctacagcga cctcagcaag ggagtgctgc gctcccggac cgtggaggac gtgctcacgc
     1021 cgctcgaaga ctgctttatg ctggactccg gcactgtcct agacttcagc gtcctcgcca
     1081 gcatcatgca gagcggccac acgcgcatcc cagtgtacga ggaggagcgc tccaacatcg
     1141 tggacatgct ctacctcaaa gacttggcta tcgttgagcc cgaggactgc acaccgctca
     1201 gcaccatcac ccgcttctac aaccatccac tccactttgt cttcaacgat accaaactgg
     1261 acgctgtcct ggaggagttc aagcgaggca agtcccacct ggccattgtg cagaaggtga
     1321 acaatgaggg cgagggcgac cccttctacg aggtgctggg cctggtcacc ctggaggacg
     1381 tcatcgagga gatcatcaag tctgagatct tggatgagtc tgaagactac tcagacacaa
     1441 aggtgaggaa gaagaccgtc gccctgggag ctcctctcaa gcgaaaggag gaattctcct
     1501 tattcaaggt gtctgatgat gaatataaag taaaaatctc gcctcagctg ctcctggcca
     1561 cccagcgctt cctttcccga gaggtggatg tgttcagccc attgcgagtc tctgagaaag
     1621 tcttgctgca cctgctgaag catcccagtg tcaaccagga ggtgacgttt gacgagagca
     1681 accgcctggc cgcacaccat tatctgtacc agcgcagcca gccagtagat tacttcattc
     1741 tcattctgca gggcagagtc gaggtcgaaa ttgggaaaga gggcctgaag ttcgagaacg
     1801 gggccttcac gtactatgga gtgtccgccc tgacagcccc atcctcagct caccagtccc
     1861 cagtgtcttc acgccagctc atccgccatg acgtgcagcc tgaaccagcc gatggtaccc
     1921 gctcctgcac atactgtcct gactacactg tgagggccct ttccgacctg cagctcatta
     1981 aggtcacacg gctgcagtac cttaatgcac tcctggctac ccgagcccaa agcttgcctc
     2041 catccccaga gaacgctgag ctccaggcta tcccaggcag ccagaccagg ctccttggtg
     2101 acaagtccag agagacagca gggtccacca acagcagacc cagcatccca gtggaggaga
     2161 gccctgggcg gaacccagga gtgtaactgc ttgccggaca gccccgagct ggaaatggac
     2221 aagcgtttgg ggagctggga gagccgagca ggagcttcat gccagcctgt ccccacctat
     2281 cctggccacg ttttagatgg cccttgtaag ctgtgggtcc tgagccgcct cggtgccaga
     2341 gcctccagcc gtcctgctgt ccttgaggag atggggttga caaagcggcc ctccagaagc
     2401 ctgtttccga ggggacaaaa gaaacagcgt catctctagt ccccagctcc cagcttcccc
     2461 ggtgctgtaa cagcacagtg tgtttatgtg tctccctgag cccagggcca tgcgggtaca
     2521 gccactgcct ttacatggcc ctggcctgtg ctcattctgc ttttggttgg ccaaccctct
     2581 gtcagtggcg ccactttctg agcaagccaa gagtgctgag ttttgatgga agtgttcaaa
     2641 tccatggccc tgccgtgtac ttcttggctt cccctacaat gccatatttt gattcatgta
     2701 ccccagtttc tcatgtgcca aatctaagag cacagctccc caataatctg tgccccggtt
     2761 ccgctccctc ctgtggagga agcccctctg gctcctcaag tcatgagcag gctggcccag
     2821 ggtcgccttg catttctttc ccacttgggc acggcgccac cacagtattg tcgatttctg
     2881 tttgaggtca tttgtggaag gccaaaggtc agtgttgact gacctggggc cgtggcgcct
     2941 gctgtacctg tcttgtgctc ttgccctgag cacccaggaa ggtgtgcagc agtgcaccgt
     3001 ggagcagcag tcagtgaggc ggttgtaagc ctgcaacgtc cttgtcactt gctgagaagt
     3061 cagggttttc tcgtatctct gaaatactca aactctgtgt gcttttgtct ttccagtgat
     3121 gttttagaga cacgggtgga aagattcttt ctcttctagt ttacctatac ttttccacag
     3181 tttcagctct gggacaatag attggggtgg gaagggcgga tttctggaac cattcttaaa
     3241 agaatatggg cccttgtgag acttggaagc taagagaaca gtggtacgct tgctgaaaaa
     3301 aatattataa cagaatgtac tctgagaaca aacccaggtt ggaaacaaat actttgaatt
     3361 acctgtctcc aaaacagaat tctaaatttc ggctgaacct cagaatcgag ttagaacctt
     3421 ggatgcgtat gctcaccttg aacccccagg gctgtggtcc tgaagtggtt ttaacctcct
     3481 cctagaagag tcccctatgc cctttaccat cacctcctaa agttaacgtg ttagataacc
     3541 ttgttgcatt taccagaact caaatgttaa cattggagta ctcaactgag gccttgattt
     3601 agatctcact tttttttttt tttgatttct ggcaattgga atccagatgc caggatgcac
     3661 ttggagctgt cgcttcttta gacctaacta cagtaattgc aggttcatag gaagtggcaa
     3721 agacgcagag cccttgtacc ctttatctgg ctttccccag tgctcccatg tcactaacca
     3781 tagtgtgcag ggctgtgggg ctctgcactc tgccacctct gtagacccaa gtaactgctg
     3841 gagaatacta acccgctgga ctgtccctcg gagccacctg cccccgccct aagccctggg
     3901 accatagact gttccataga ctgttcctca gctctgtcat tttgtcatgt caagaatgtc
     3961 gtttgagggg ctgtgttgcg tgcagctgga ctttgggatt gacttcatcc agcacagtgc
     4021 tctggaggct gttccaggtc agtgtgtcag tggctcgctc ctccttgcca aatgatgtcc
     4081 cgtggtgtat tcagtgtcct gtcagaggac atctgggttg tttgcagttt ttggcctttt
     4141 caaaataaag ctgctatgaa cattcacgta cagatacggt gtgaagactg gtgtccgcct
     4201 gggatgtgcc agcaacacag gtgccatgac gtttacctta aaaaagaacc tgcctggcct
     4261 tggagcggag ctgtgcacaa gtttaaattc ctacaggaaa tgtaggaatg atctggtttc
     4321 tccccacccc gacccatggg ccaatgacca tcagtccttt gctgtctgtg gttcttgtct
     4381 gcttttcctt ggtctcgtcc atgagcctgt tcgtgttttc agcttggcaa ctggtctgta
     4441 ttcctttcca tgtgtctgtg catctccacc ccacccccat cttttttttt ttctcttggg
     4501 aactctcttg ggaactcttc agatatttag attccaaaat ccttcgttgg atttttggtt
     4561 tgcaaagatt atctgtgtag tgctgtattc tagatctgaa ttgtgacccc agagcttgta
     4621 tactaaagat tgaatccctg ggctgctctg ttagtgggtt ctcctgagtt catcagggct
     4681 ctgacctctg ccatgttctc cctctgtaaa gtgtgtggtc taaaggacca agcagccaca
     4741 ggctcccatg ggcctccatc tcagtaacat taactgtgtt ctcaccgcaa ggtcttgtac
     4801 aggtggaggg tttggttggg ggggggttgt tttttgttgt ttgtttgttt gtttgttttt
     4861 ggtgttttaa gccaagagtt tgtctgtata gcccaggctg gcctcaaact cagagattca
     4921 ctgcctctga ctctcaagtg ctgggtctaa aggcatgctc tgccacgcct ggctcatctt
     4981 aaaggttttt gtgattaaag tctctctctc tctctttttt ttgttttgtt tttcgagaca
     5041 tggtttctct gtgtagccct ggccgtcctg aaactcactc tgtagaccag gctggcattg
     5101 aactcagaaa tccacctgcc tctgcctccc aagtgctgga attaaaggcg tgtgccacca
     5161 ctgcccggcc tgattaaatt catttttatc aaa
//
