LOCUS       NM_001081375             530 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus cornifelin (Cnfn), transcript variant 2, mRNA.
ACCESSION   NM_001081375 XM_902356
VERSION     NM_001081375.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Michibata,H., Chiba,H., Wakimoto,K., Seishima,M., Kawasaki,S.,
            Okubo,K., Mitsui,H., Torii,H. and Imai,Y.
  TITLE     Identification and characterization of a novel component of the
            cornified envelope, cornifelin
  JOURNAL   Biochem Biophys Res Commun 318 (4), 803-813 (2004)
   PUBMED   15147942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156992.13.
            
            On Feb 6, 2007 this sequence version replaced XM_902356.2.
            
            Transcript Variant: This variant (2) lacks an exon in the 5' coding
            region and uses a downstream start codon, compared to variant 1. It
            encodes isoform 2 which has a shorter N-terminus, compared to
            isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY708861.1, AK008979.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AC156992.13        8235-8294
            61-171              AC156992.13        9483-9593
            172-308             AC156992.13        9857-9993
            309-530             AC156992.13        10122-10343
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.78 cM"
     gene            1..530
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /note="cornifelin"
                     /db_xref="GeneID:72383"
                     /db_xref="MGI:MGI:1919633"
     exon            1..60
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            61..171
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..398
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="cornifelin isoform 2"
                     /protein_id="NP_001074844.1"
                     /db_xref="CCDS:CCDS39838.1"
                     /db_xref="GeneID:72383"
                     /db_xref="MGI:MGI:1919633"
                     /translation="MSYPVTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAP
                     LCLACRISDDFGECCCAPYLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQ
                     MARELKIRE"
     exon            172..308
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            309..530
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      507..512
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      526
                     /gene="Cnfn"
                     /gene_synonym="2210418J09Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaacttagtg tctgctgtca ccaagaacct ctatctccat cccctcacgt ggatctgcag
       61 ccatgtcata tccagtgact agtcagcctc agtgcgccaa cacctgctac cagacacagc
      121 tcagcgattg gcacacgggc ctcaccgact gttgcaacga catgcccgtc tgtctgtgcg
      181 gcactttcgc cccgctgtgc ctggcctgcc gcatctccga tgactttggg gagtgctgct
      241 gtgcgcccta cctgcccgga ggtctgcact ctctgcgcac cggcatgagg gagcgctacc
      301 acatccaggg ctccgtcggg cacgactggg ctgccctcac cttttgcctg ccctgcgccc
      361 tctgtcagat ggcgcgggaa ctgaaaatcc gagagtaagg acattcttgg tccttggtcc
      421 ttggtcttgc ctggcctccc tgggaggcca ctccttggaa agcctgtccc actgcccctg
      481 tcccaccgcc aaaaaaatac acccacaata aaaacctgaa aaccaacccc
//
