LOCUS       NM_001371269            1644 bp    mRNA    linear   ROD 10-JUL-2024
DEFINITION  Mus musculus cyclic nucleotide binding domain containing 1 (Cnbd1),
            mRNA.
ACCESSION   NM_001371269
VERSION     NM_001371269.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1644)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1644)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1644)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL773522.15, AL772203.14 and AL805966.7.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.178496.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849384
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AL773522.15        54155-54306         c
            153-225             AL773522.15        35059-35131         c
            226-339             AL773522.15        29900-30013         c
            340-495             AL772203.14        142746-142901       c
            496-641             AL805966.7         173640-173785       c
            642-829             AL805966.7         161620-161807       c
            830-961             AL805966.7         154260-154391       c
            962-1094            AL805966.7         152632-152764       c
            1095-1204           AL805966.7         128693-128802       c
            1205-1361           AL805966.7         127092-127248       c
            1362-1429           AL805966.7         82297-82364         c
            1430-1489           AL805966.7         52351-52410         c
            1490-1644           AL805966.7         34624-34778         c
FEATURES             Location/Qualifiers
     source          1..1644
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 7.28 cM"
     gene            1..1644
                     /gene="Cnbd1"
                     /note="cyclic nucleotide binding domain containing 1"
                     /db_xref="GeneID:435772"
                     /db_xref="MGI:MGI:3650508"
     exon            1..152
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1609
                     /gene="Cnbd1"
                     /codon_start=1
                     /product="cyclic nucleotide-binding domain-containing
                     protein 1"
                     /protein_id="NP_001358198.1"
                     /db_xref="GeneID:435772"
                     /db_xref="MGI:MGI:3650508"
                     /translation="MPVDSLPNSILAHMLAISNVPPPPLHSLPRLRLSKTINYGQLNA
                     LCHIRGLKSDQHSSLRSEAHDAFIKQYPQIFLREKTVLPKVSHQVDKRKSALKLAEKK
                     HQPVMAHNISAYLREARGGPSIDEKEITEEKFQEFLNILKKLPVYRTTHEHNMVWKIL
                     QSIPELTSQFSNEDLKILSKKVISETWIKGSTVIGDDGLYVLLTGQARRRVKVFRSLI
                     EENDSIITSLYRDSFLFDAELQDSTVAQLYVPSKKLIVKQWGIFGSLKDRAEMDERDR
                     SVVTDYDCEILKIAAKEYEKLKLEKVKHENAQKLKLIRKCPFYETWPTLSIWELVSIC
                     KFKNFPPGHVLVESGTVISFVGYINSGYCNIYRNVVGLVDLPINKVKKIKKLVYMGKL
                     KEKESFGEISILLQAPFTCTVITGQEVEMAVIEDKDIQGKSLDPVTKELMIQTAKPTF
                     GHLTEEDVKSEYIKSVQAKEWKYFKNKTIQRILHSNGVLPGFGRWEHYWPTFPKNLKK
                     PLISYS"
     exon            153..225
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            226..339
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            340..495
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            496..641
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            642..829
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..961
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1094
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1204
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1361
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1429
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1489
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1644
                     /gene="Cnbd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1583..1588
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cnbd1"
                     /note="hexamer: AAGAAA"
     polyA_site      1630
                     /gene="Cnbd1"
                     /note="major polyA site"
     polyA_site      1644
                     /gene="Cnbd1"
                     /note="major polyA site"
ORIGIN      
        1 aaagataagt atgttcctct aacactcaag tagtctctat ccacctgcct tataagatga
       61 caagatgcct gtggattctc ttccaaacag tattttggcc cacatgttag ccattagcaa
      121 tgtgcctcct cctccacttc acagtttgcc acgcctgaga ctgagcaaaa ccattaatta
      181 tggtcagctg aatgccttat gccacattag aggactaaag agcgaccagc attcttccct
      241 tcgttcggaa gctcatgatg ctttcatcaa gcaatatcct caaatattcc tgcgtgaaaa
      301 gacagtgttg cctaaagttt ctcaccaggt tgacaaaaga aaatctgctc taaagctagc
      361 agaaaagaaa caccaacctg ttatggcaca caacatatct gcctatctta gagaagctcg
      421 tggtggccct tctattgatg aaaaagaaat aactgaagaa aagttccagg agttcttaaa
      481 tatcttaaag aagctgccag tttatagaac aacacatgag cataacatgg tgtggaagat
      541 tttgcagagt attccagagt taacctctca atttagcaat gaggatctga aaatcctgag
      601 taagaaagtg atatctgaaa cctggatcaa aggtagcaca gtgattggtg atgatggact
      661 ttatgtctta ctgacgggcc aggctcgacg tcgtgtaaag gtgtttagaa gtctgatcga
      721 agaaaatgac tcaatcatca cttcactcta cagggatagt tttctttttg atgcagagtt
      781 acaagattct acagtggctc agctgtatgt accttcaaag aaattaatag tgaaacagtg
      841 gggtatcttt ggatcactga aagacagagc tgaaatggat gaacgtgacc gttcagttgt
      901 gacagattat gactgtgaaa tcctgaaaat agctgcaaag gagtatgaga agttaaaatt
      961 ggaaaaagta aagcatgaaa atgcacaaaa gttgaaatta atccgcaagt gtccttttta
     1021 tgaaacctgg cctactttat ccatatggga gctagtttca atttgtaaat tcaaaaattt
     1081 tcctccagga catgtgttag tagaaagtgg aactgtcatt tcatttgtgg gttatatcaa
     1141 ctctggatat tgtaacattt acagaaatgt tgttggactt gtggacctac caataaacaa
     1201 agtgaaaaaa attaaaaaac ttgtttatat gggtaaactt aaggagaagg agtcctttgg
     1261 tgagatcagt attcttcttc aagctccctt cacatgcaca gttattactg gacaagaagt
     1321 tgagatggca gttattgaag ataaggacat acagggtaaa tcactagatc ctgtgaccaa
     1381 ggaacttatg attcaaactg caaaaccaac ttttgggcat ctgacagaag aagacgtaaa
     1441 aagtgaatac ataaagagtg tacaagcaaa agaatggaaa tatttcaaga ataagacaat
     1501 tcaaagaatc ttgcatagta acggagttct tcctggcttt ggaagatggg aacattattg
     1561 gccaacgttc cctaagaatc tcaagaaacc tcttatcagt tactcatgat acaagtcttt
     1621 ttagagtcca tctttagtat caaa
//
