LOCUS       NM_026066                890 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus CKLF-like MARVEL transmembrane domain containing 5
            (Cmtm5), transcript variant 2, mRNA.
ACCESSION   NM_026066 XM_892823
VERSION     NM_026066.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 890)
  AUTHORS   Zhan,J., Gao,Y., Heinig,L., Beecken,M., Huo,Y., Zhang,W., Wang,P.,
            Wei,T., Tian,R., Han,W., Yu,A.C.H., Kipp,M. and Kaddatz,H.
  TITLE     Loss of the Novel Myelin Protein CMTM5 in Multiple Sclerosis
            Lesions and Its Involvement in Oligodendroglial Stress Responses
  JOURNAL   Cells 12 (16), 2085 (2023)
   PUBMED   37626895
  REMARK    GeneRIF: Loss of the Novel Myelin Protein CMTM5 in Multiple
            Sclerosis Lesions and Its Involvement in Oligodendroglial Stress
            Responses.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 890)
  AUTHORS   Buscham,T.J., Eichel-Vogel,M.A., Steyer,A.M., Jahn,O., Strenzke,N.,
            Dardawal,R., Memhave,T.R., Siems,S.B., Muller,C., Meschkat,M.,
            Sun,T., Ruhwedel,T., Mobius,W., Kramer-Albers,E.M., Boretius,S.,
            Nave,K.A. and Werner,H.B.
  TITLE     Progressive axonopathy when oligodendrocytes lack the myelin
            protein CMTM5
  JOURNAL   Elife 11, e75523 (2022)
   PUBMED   35274615
  REMARK    GeneRIF: Progressive axonopathy when oligodendrocytes lack the
            myelin protein CMTM5.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 890)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 890)
  AUTHORS   Ge,Y., Waldemer,R.J., Nalluri,R., Nuzzi,P.D. and Chen,J.
  TITLE     RNAi screen reveals potentially novel roles of cytokines in
            myoblast differentiation
  JOURNAL   PLoS One 8 (7), e68068 (2013)
   PUBMED   23844157
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 890)
  AUTHORS   Han,W., Ding,P., Xu,M., Wang,L., Rui,M., Shi,S., Liu,Y., Zheng,Y.,
            Chen,Y., Yang,T. and Ma,D.
  TITLE     Identification of eight genes encoding chemokine-like factor
            superfamily members 1-8 (CKLFSF1-8) by in silico cloning and
            experimental validation
  JOURNAL   Genomics 81 (6), 609-617 (2003)
   PUBMED   12782130
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK013666.1.
            
            On Apr 6, 2007 this sequence version replaced NM_026066.1.
            
            Transcript Variant: This variant (2) lacks an exon in the coding
            region, compared to variant 1. The encoded isoform (2) is shorter,
            compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013666.1, BY712641.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-890               AK013666.1         1-890
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 28.0 cM"
     gene            1..890
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /note="CKLF-like MARVEL transmembrane domain containing 5"
                     /db_xref="GeneID:67272"
                     /db_xref="MGI:MGI:2447164"
     exon            1..314
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /inference="alignment:Splign:2.1.0"
     exon            315..467
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /inference="alignment:Splign:2.1.0"
     exon            468..560
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /inference="alignment:Splign:2.1.0"
     exon            561..645
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /inference="alignment:Splign:2.1.0"
     exon            646..890
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      867..872
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /note="hexamer: ATTAAA"
     polyA_site      887
                     /gene="Cmtm5"
                     /gene_synonym="1500005P16Rik; 2900052H21Rik; Cklfsf5"
                     /note="major polyA site"
ORIGIN      
        1 ggcacagctg ggtgaagccc atccgggcaa gccttccctg gttactactg cctttcccca
       61 gagtcctaca gcaggcccct gcttcacttt caggctcctg tctgcttctc taaccagatt
      121 tctgtttccc ttcctgggct gctgggaatc tggtgaggga gagtctgtgt cccgtgagcc
      181 tcacagagat gttcagtgct tgggatcgcc gggaacggcc cccagaggaa ggagcagctg
      241 cagggctcca gggcttcgga gtggacaaga ccttcctgtc ttccctcaaa ggcatcctgc
      301 tggaaactga gctggccctg accttcatca tcttcatttg cttcacggcc tccatctctg
      361 cctacatggc tgcagcgttg ctagagttcc tcatcacact ggccttcctc ttcctctgcg
      421 ccacgcagta ctaccagcgc ttcgataggc tcaactggcc ttgtctggac ttcctccggt
      481 gtctcagcgc catcgtcatc ttcctggtgg tctcctttgc tgctgtgacc tcgagggagg
      541 gagctgccat tgctgctttt gtttttggca tcatcctggt ctccgtcttt gcctatgatg
      601 cattcaagat ctaccgaact gagctgatgc ccagtaccac tgagggggac cagcagtgat
      661 tccagggtta cctggctccc acgaccagac acaaggaacc gtggagccca tctttgtcat
      721 ctttgaattc accgaacccc aagtacccac catctatatt ccacgttttc agagatgtgc
      781 gcttgagaag tcccaggcac ctgtgggaac tggtgaagtt ctggaggctg gggcaggttg
      841 ttgctgggcc tccaagttac tcccaaatta aaaaaaaaaa aatcaaatcc
//
