LOCUS       NM_024217               1616 bp    mRNA    linear   ROD 03-SEP-2024
DEFINITION  Mus musculus CKLF-like MARVEL transmembrane domain containing 3
            (Cmtm3), mRNA.
ACCESSION   NM_024217 XM_913155
VERSION     NM_024217.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1616)
  AUTHORS   Shen,E., Piao,M., Li,Y., Wu,Y., Li,S., Lee,S.H., Jin,L. and
            Lee,K.Y.
  TITLE     CMTM3 Suppresses Proliferation and Osteogenic Transdifferentiation
            of C2C12 Myoblasts through p53 Upregulation
  JOURNAL   Cells 13 (16), 1352 (2024)
   PUBMED   39195242
  REMARK    GeneRIF: CMTM3 Suppresses Proliferation and Osteogenic
            Transdifferentiation of C2C12 Myoblasts through p53 Upregulation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1616)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1616)
  AUTHORS   Ye,J., Yan,S., Liu,R., Weng,L., Jia,B., Jia,S., Xiong,Y., Zhou,Y.,
            Leng,M., Zhao,J., Yang,F. and Zheng,M.
  TITLE     CMTM3 deficiency induces cardiac hypertrophy by regulating MAPK/ERK
            signaling
  JOURNAL   Biochem Biophys Res Commun 667, 162-169 (2023)
   PUBMED   37229825
  REMARK    GeneRIF: CMTM3 deficiency induces cardiac hypertrophy by regulating
            MAPK/ERK signaling.
REFERENCE   4  (bases 1 to 1616)
  AUTHORS   Wang,J., Chu,H., Wang,Z., Wang,X., Liu,X., Song,Z. and Liu,F.
  TITLE     In vivo study revealed pro-tumorigenic effect of CMTM3 in
            hepatocellular carcinoma involving the regulation of peroxisome
            proliferator-activated receptor gamma (PPARgamma)
  JOURNAL   Cell Oncol (Dordr) 46 (1), 49-64 (2023)
   PUBMED   36284038
  REMARK    GeneRIF: In vivo study revealed pro-tumorigenic effect of CMTM3 in
            hepatocellular carcinoma involving the regulation of peroxisome
            proliferator-activated receptor gamma (PPARgamma).
REFERENCE   5  (bases 1 to 1616)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1616)
  AUTHORS   Wilm,B., James,R.G., Schultheiss,T.M. and Hogan,B.L.
  TITLE     The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus
            intermediate mesoderm cell fate
  JOURNAL   Dev Biol 271 (1), 176-189 (2004)
   PUBMED   15196959
REFERENCE   7  (bases 1 to 1616)
  AUTHORS   Imamura,Y., Katahira,T. and Kitamura,D.
  TITLE     Identification and characterization of a novel BASH N
            terminus-associated protein, BNAS2
  JOURNAL   J Biol Chem 279 (25), 26425-26432 (2004)
   PUBMED   15087455
REFERENCE   8  (bases 1 to 1616)
  AUTHORS   Han,W., Ding,P., Xu,M., Wang,L., Rui,M., Shi,S., Liu,Y., Zheng,Y.,
            Chen,Y., Yang,T. and Ma,D.
  TITLE     Identification of eight genes encoding chemokine-like factor
            superfamily members 1-8 (CKLFSF1-8) by in silico cloning and
            experimental validation
  JOURNAL   Genomics 81 (6), 609-617 (2003)
   PUBMED   12782130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121952.4.
            
            On Mar 21, 2007 this sequence version replaced NM_024217.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY241870.1, BC003230.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               AC121952.4         66133-66434         c
            303-458             AC121952.4         63115-63270         c
            459-554             AC121952.4         62156-62251         c
            555-675             AC121952.4         61636-61756         c
            676-1616            AC121952.4         59356-60296         c
FEATURES             Location/Qualifiers
     source          1..1616
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.04 cM"
     gene            1..1616
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /note="CKLF-like MARVEL transmembrane domain containing 3"
                     /db_xref="GeneID:68119"
                     /db_xref="MGI:MGI:2447162"
     exon            1..302
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            303..458
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            459..554
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            555..675
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     exon            676..1616
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1597..1602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /note="hexamer: ATTAAA"
     polyA_site      1616
                     /gene="Cmtm3"
                     /gene_synonym="9430096L06Rik; BNAS2; Cklfsf3"
                     /note="major polyA site"
ORIGIN      
        1 tgtgggtggg gatgggggag gtgggcggga cagcggagga tgagtccccg gcctagtcta
       61 actccacttt ttcttcttcc gcacagcggg tttccgcttc cctccagggc ggtgggtgag
      121 gcagtgaggc ccaggctcga ccagatagcg ccgctatgtg gcccccggac gcagagccag
      181 agcccgatcc agagtccgcg catggccccc gaagtggcag gacagtgccg ggactccgag
      241 ccctgttgcc cgcgcgcgcc ttcctctgct ctctcaaagg ccgcctcctg ctggccgagt
      301 cgggtctttc attcatcacc ttcatctgct acgtggtgtc ctccgcatct gccttcctca
      361 cagtgcctct gctggagttt ctgttggccg tttacttcct ctttgctgat gccatgcagc
      421 tgaatgacaa atggcagggt ttgtgctggc ccatgatgga cttcctgcgc tgtgtcaccg
      481 ctgccctcat ctacttcgtc atctccatca ctgctgtcgc caaatactca gatggggctt
      541 acaaagcagc tggagttttt ggcttttttg ccacaattgt gttcgcaatt gacttctacc
      601 tgatctttaa tgaagtggcc aaattcctca agcaaggaga ctctgggaat gagaccacag
      661 cccataggac agaagaagag aactccaact cggactcaga ctctgactaa aggcctgtct
      721 gagcttaaca actagagcca ctcggccctc tcacccacgc tgtcctgacg gggctcctgg
      781 agcatggcag gaatgcccat gggagaacag accgaggagc ccgtctctca agattacact
      841 cccgaggcct cacattcaaa attggctgtg ctggcttggc actgctgagc tagcgtggta
      901 gggcacgttg acaagccttc cttctcccct ttctgtcctt gagccccttt aacctcactg
      961 cccccaccga agcacacatc aaacggagcc aatcactaca gccaatcatg tggcagcatg
     1021 ggggtggggt gggactttct gttactaaca gggacagata aaaccacagc aggctggacc
     1081 accagcccca aacctgcact gcattgagat gactttcagg aaccttttat tcaagaagtt
     1141 tccctcctca ctgtgaaata gggagaaacc tagctagcca agtcttccat tagaggtctg
     1201 aggccttttc agaaacggac ccaaagattt gtttactagg gcccagagac agggagccaa
     1261 ccagtatagt ggcagtgacc aagtcacaag tggctgggca ggcccagcca agcactctct
     1321 tcctggggac cctaaaagac aaagtgcttc ctctggacac ctgggcagga ccactggtga
     1381 catggacttc tctgtagtcc cttgggggcg gttactgtgt gtgtctttga tggtgttttc
     1441 taactttttt atattttttt aatacaaaaa caatgtaaca aatggtcttt tctgtaacct
     1501 aagaggcccc atgaataagg gcccatgtct tgggcatttg taaccttttt atcttgcatg
     1561 tgaattccct ccctttaaaa aaaaaagtca caatggatta aaacaaactg actaca
//
