LOCUS       NP_001405947             439 aa            linear   ROD 01-MAY-2025
DEFINITION  clusterin-associated protein 1 isoform 2 [Mus musculus].
ACCESSION   NP_001405947
VERSION     NP_001405947.1
DBSOURCE    REFSEQ: accession NM_001419018.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 439)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 439)
  AUTHORS   Shukla,S., Haenold,R., Urbanek,P., Frappart,L., Monajembashi,S.,
            Grigaravicius,P., Nagel,S., Min,W.K., Tapias,A., Kassel,O.,
            Heuer,H., Wang,Z.Q., Ploubidou,A. and Herrlich,P.
  TITLE     TRIP6 functions in brain ciliogenesis
  JOURNAL   Nat Commun 12 (1), 5887 (2021)
   PUBMED   34620853
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 439)
  AUTHORS   Lamri,L., Twan,W.K., Katoh,T.A., Botilde,Y., Takaoka,K., Ikawa,Y.,
            Nishimura,H., Fukumoto,A., Minegishi,K., Mizuno,K. and Hamada,H.
  TITLE     Ciliogenesis-coupled accumulation of IFT-B proteins in a novel
            cytoplasmic compartment
  JOURNAL   Genes Cells 24 (11), 731-745 (2019)
   PUBMED   31554018
REFERENCE   4  (residues 1 to 439)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 439)
  AUTHORS   Katoh,Y., Terada,M., Nishijima,Y., Takei,R., Nozaki,S., Hamada,H.
            and Nakayama,K.
  TITLE     Overall Architecture of the Intraflagellar Transport (IFT)-B
            Complex Containing Cluap1/IFT38 as an Essential Component of the
            IFT-B Peripheral Subcomplex
  JOURNAL   J Biol Chem 291 (21), 10962-10975 (2016)
   PUBMED   26980730
  REMARK    GeneRIF: a ciliogenesis defect of Cluap1-deficient embryonic
            fibroblasts was rescued by exogenous expression of wild-type Cluap1
            but not by mutant Cluap1 lacking the binding ability to other IFT-B
            components
REFERENCE   6  (residues 1 to 439)
  AUTHORS   Botilde,Y., Yoshiba,S., Shinohara,K., Hasegawa,T., Nishimura,H.,
            Shiratori,H. and Hamada,H.
  TITLE     Cluap1 localizes preferentially to the base and tip of cilia and is
            required for ciliogenesis in the mouse embryo
  JOURNAL   Dev Biol 381 (1), 203-212 (2013)
   PUBMED   23742838
  REMARK    GeneRIF: Cluap1 contributes to ciliogenesis by regulating the
            intraflagellar transport cycle at the base and tip of the cilium
REFERENCE   7  (residues 1 to 439)
  AUTHORS   Pasek,R.C., Berbari,N.F., Lewis,W.R., Kesterson,R.A. and Yoder,B.K.
  TITLE     Mammalian Clusterin associated protein 1 is an evolutionarily
            conserved protein required for ciliogenesis
  JOURNAL   Cilia 1 (1), 20 (2012)
   PUBMED   23351563
  REMARK    Publication Status: Online-Only
REFERENCE   8  (residues 1 to 439)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
REFERENCE   9  (residues 1 to 439)
  AUTHORS   Marshall,W.F.
  TITLE     Human cilia proteome contains homolog of zebrafish polycystic
            kidney disease gene qilin
  JOURNAL   Curr Biol 14 (21), R913-R914 (2004)
   PUBMED   15530380
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129021.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422598.460828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143, SAMN02415137
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.3 cM"
     Protein         1..439
                     /product="clusterin-associated protein 1 isoform 2"
                     /calculated_mol_wt=50687
     Region          14..283
                     /region_name="Cluap1"
                     /note="Clusterin-associated protein-1; pfam10234"
                     /db_xref="CDD:463013"
     CDS             1..439
                     /gene="Cluap1"
                     /gene_synonym="2310030D15Rik; 2610111M03Rik"
                     /coded_by="NM_001419018.1:146..1465"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:76779"
                     /db_xref="MGI:MGI:1924029"
ORIGIN      
        1 msfrdlrnft emmralgypr hismenfrtp nfglvsevll wlvkryepqt dipsdieteq
       61 drvffikaia qfmatkahik lntkklyqad gyavkellki tsvlynamkt kgmegsnvge
      121 ediskfkfdl gskiadlkaa rqlaseitak gaslydllgk evelrelrte aiarpleine
      181 tekvmriaik dllaqvqktk dllnnvasde anleakiekr klelernrkr lqtlqsvrpa
      241 fmdeyekvee dlqkqydvyl ekfrnlayle qqledhhrme qerfeeaent lrlmqnklke
      301 eekrllksgs nddsdidiqe ddesdseled rrmskprtam evlmqevqss smvmhsysps
      361 tldaearsrv qgrpskrivg amqggdsded edsedseidm eddeeddddl edesialspa
      421 kpsrrirkpe pldesdndf
//
