LOCUS       NM_178669               3315 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus clarin 3 (Clrn3), mRNA.
ACCESSION   NM_178669
VERSION     NM_178669.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3315)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK146608.1.
            
            On Apr 6, 2007 this sequence version replaced NM_178669.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146608.1, BC036176.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849380,
                                           SAMN00849385 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3315              AK146608.1         2-3316
FEATURES             Location/Qualifiers
     source          1..3315
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 81.27 cM"
     gene            1..3315
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /note="clarin 3"
                     /db_xref="GeneID:212070"
                     /db_xref="MGI:MGI:2142022"
     exon            1..380
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..832
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /note="transmembrane protein 12"
                     /codon_start=1
                     /product="clarin-3"
                     /protein_id="NP_848784.1"
                     /db_xref="CCDS:CCDS21943.1"
                     /db_xref="GeneID:212070"
                     /db_xref="MGI:MGI:2142022"
                     /translation="MPTTQKTLMFLSGFLTSLGSVVVICSILATQAWITSRIFFTDAI
                     SNGTIVITYGLFRGTSAQELNEGLQDLDKNFEVLGILDNSSQKSLHLVVILLLILSLA
                     ASVLSSVFTFYNSISNPYQTFLGPMGVYTWNGLSASFVFLAMVLFVGNAESNHLSDKL
                     SQKLYPDTTNKRTTHTYGYSFWLTLHVIFLNIVTAVIIIFYQKARYRQKQEQRKPVEY
                     APRDGILF"
     exon            381..560
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /inference="alignment:Splign:2.1.0"
     exon            561..3315
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1986..1991
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /note="hexamer: AATAAA"
     polyA_site      2005
                     /gene="Clrn3"
                     /gene_synonym="Tmem12"
                     /note="major polyA site"
ORIGIN      
        1 agtaagcata aaacttccca ggaagacgca ggttttacat ttacaaccaa gtgctagacg
       61 tcctttctaa atactggatc ccaaatgata aggcccccaa atattctaag gttgctgttg
      121 ttttatcgcg gggagctttc ttcctgagaa aatgccaacc acacagaaaa cgttgatgtt
      181 cctgtctggc tttctcacaa gcctgggctc agttgttgtc atctgctcca ttcttgcgac
      241 tcaggcatgg atcaccagca ggattttctt tacagatgct atctccaacg gtaccattgt
      301 tattacctat gggctcttcc gtggtacgag tgctcaagag ttgaatgaag gccttcaaga
      361 tctggacaaa aactttgaag ttttagggat attggacaat tcttcccaga agtctttgca
      421 cctggtggtc atcctcctcc tgatcctgag tctggcagct tccgtgctga gctcagtgtt
      481 caccttctac aacagcatca gcaaccctta ccagacgttc ctgggaccta tgggtgtcta
      541 tacctggaat ggactcagcg catcctttgt gtttctggcc atggttctgt tcgtggggaa
      601 tgccgagtcc aaccatctct cagacaagct ctcccagaag ctttatccag ataccacaaa
      661 caagagaaca acccacactt acggatactc gttttggctc accctgcatg tcatctttct
      721 caatattgtc actgcggtca tcatcatttt ctatcagaag gcccgatacc ggcagaagca
      781 ggagcagagg aagccggtgg aatatgctcc aagggatggc attttattct gagtcctgtc
      841 tcatagccca tttgcactgt ctctgccaaa ctgactcact cctctgaaca ctgcatggca
      901 gagcaactgt caggtgccat cgcttctgga accacgacac catgtcctgc ctatagatgg
      961 tgcttgtatc ttcctccatg gacttcctcc tgaaaagagt tttctcctaa gatcaggaaa
     1021 atgattggga agggctgtgg tctagagtaa tccaaaagag ggcagcctgg ggcctgcagg
     1081 cctttctcat ttgaccctgc tatcggcagt aatataggtc tgtggggtgt tttgcctttc
     1141 ctgtgactag ataaacagac tatagcccct atgaccttgt cctctggatt gatcaggcat
     1201 ttcggtccat gataagtata aggattttta agcagagaag cactctgaac taattttttt
     1261 cactcagaag ttagatacag aaggataaag gatgggatga ccctgtgttc tggtcccttg
     1321 gtggctgttg tgacttccag gtttctttcc ttcagtgagg gctagacact tgcagagctt
     1381 gggacttggg aagtcatgca tgaacagatt ggaggtaaaa tatggtctct tccagtaaat
     1441 agaaagtcag aaaactagca aaggcaccaa aatgtattct gcatggtttt ccagtgtgac
     1501 atttcctttt taaaacatct gattgagaac ccttcagcct ggactatcct ataggctgcc
     1561 acagtgacaa ctgacagacc tgaaaagtga cctcctttca tgtgttgacg gagtcttaaa
     1621 acagtagctc aatgacaagt ggtggatctt atgaagctag atgaccttca acactcagag
     1681 atgtgagctg ggtcgccaaa gtgttggcag cagcatgctg ggtttattta ctaccaggca
     1741 gacgagaaag acatttaata agctcttact tgactactcc aattaaaaca gttgcttagg
     1801 gttggaggtc atccctccat tgtagaacac taaggtgcct agagtgtgac aggccctggg
     1861 ttccatctct acctccgtaa aaacaaaaca agcaggtaat gacagaattg tgcttgtggt
     1921 ttgaaaggat ggatctctat catgctctcc cttgaagacc tactaattca agattacttt
     1981 tacctaataa attattaaaa ggttactata ctattttctt tactcttttc atgagtgtaa
     2041 gtgcacatgc catgatttgt gtgtctgtgt gtctctctgc gtatggaggt cagatgacaa
     2101 gcttcaagag tggattctct ccttctacca tgtgagacct ggggtttaaa ctcatgtcat
     2161 cagacttgct ggcaagcaca tttacccact gggctacctt gtaggcctgc tactaaatta
     2221 ttataaagtt tgggtttggg aagcaatggc ttaatgggta aaagtgcttg tcaccaagcc
     2281 tgatgcccct gtccactcct catcacctac acagtgaaag agctgactcc tgcaagttat
     2341 cctctgacct acacgcatgc gttgtggcat gcgcatgccc ataggcacaa tcatacttcc
     2401 ctatacaata tacaaaagaa acgcacatat gtgaaacaaa tacaatttaa agcgactcgg
     2461 tcctgttcat ttgaaaaata ttgggatata ttttaaaaat atgattataa atgtaaaaaa
     2521 tttaaactct gagtctaaaa atatttatat tcttcgaagg cctaagtttt ctattggatt
     2581 tttttgttta atgtggccat gtaataaaga ggatgtggag gtgggtgctg gcccatgccc
     2641 ttgagcccat cttcaggaat cagaagattg ccacagcttt gaagtcactc tggtatgttg
     2701 ggagttcgag gccagcagaa cttcataaag aggccctcgt ggtttgaatg agagatgtca
     2761 ccagaggctc aggagtttga atgcctgttc cccagtggtg gcactgtttg gggatgctac
     2821 attacctgta gggggcagag ctttgctaga ggaagtatgt cactggggtg ggctttgaga
     2881 gttcatagac tcatctcact tcctgttttc tctctctgct tcctgctcct ggagttggcc
     2941 ctgccagttg ccaccatgcc tccttgacat tgtagactct ccttccggaa tcatgagccc
     3001 aaatagactc tttctttgta agtttccttt atcatgatat tttatctcac caacagaaaa
     3061 gcaatgaata catatgggct tgcctcaagc cagcaagcat acaaacaaaa ccattacttt
     3121 gtcttgttat gaggtaggtt gcaaagttca tcacatttgc aaaagaacga atataaacca
     3181 ctatgttcac cagatgtgtt ggtacatgac tttgggaaac tgaggcagaa agatcaggga
     3241 ttccaggcaa gcctgggaga cttagcaaga cacatgggga taaaaagaaa agtaaataaa
     3301 tgaacagaaa aatgt
//
