LOCUS       NM_146047               2378 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus CLPTM1-like (Clptm1l), mRNA.
ACCESSION   NM_146047
VERSION     NM_146047.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2378)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2378)
  AUTHORS   Trezise,S., Karnowski,A., Fedele,P.L., Mithraprabhu,S., Liao,Y.,
            D'Costa,K., Kueh,A.J., Hardy,M.P., Owczarek,C.M., Herold,M.J.,
            Spencer,A., Shi,W., Willis,S.N., Nutt,S.L. and Corcoran,L.M.
  TITLE     Mining the Plasma Cell Transcriptome for Novel Cell Surface
            Proteins
  JOURNAL   Int J Mol Sci 19 (8), 2161 (2018)
   PUBMED   30042348
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2378)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   4  (bases 1 to 2378)
  AUTHORS   Chiellini,C., Costa,M., Novelli,S.E., Amri,E.Z., Benzi,L.,
            Bertacca,A., Cohen,P., Del Prato,S., Friedman,J.M. and Maffei,M.
  TITLE     Identification of cathepsin K as a novel marker of adiposity in
            white adipose tissue
  JOURNAL   J Cell Physiol 195 (2), 309-321 (2003)
   PUBMED   12652657
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158359.2, AK048357.1 and AK032295.1.
            
            On Mar 26, 2011 this sequence version replaced NM_146047.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032295.1, AK048357.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               AC158359.2         52034-52137
            105-2342            AK048357.1         2-2239
            2343-2378           AK032295.1         2307-2342
FEATURES             Location/Qualifiers
     source          1..2378
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 40.12 cM"
     gene            1..2378
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /note="CLPTM1-like"
                     /db_xref="GeneID:218335"
                     /db_xref="MGI:MGI:2442892"
     exon            1..398
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..1856
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /note="cisplatin resistance related protein CRR9p; cleft
                     lip and palate transmembrane protein 1-like protein;
                     CLPTM1-like protein; cisplatin resistance-related protein
                     9"
                     /codon_start=1
                     /product="lipid scramblase CLPTM1L"
                     /protein_id="NP_666159.2"
                     /db_xref="CCDS:CCDS56894.1"
                     /db_xref="GeneID:218335"
                     /db_xref="MGI:MGI:2442892"
                     /translation="MWSGRSSFTSLVVGVFLVYVVHTCWVMYGIVYTRPCSGDSNCIQ
                     PYLALRPKLQLSVYTTTRSSLGAENNVDLILNVEDFDVDSKFERTVNVSVPKKTRNNG
                     TLYAYIFLHHAGILPWQDGKQVHVVSTLTTYMIPKPEEINLLTGESATQQQIEAEKKP
                     SNALDEPVSHWRPRLTLNVMVDDFVFDGSSLPADVHRYMKMIQLGKTVHYLPILFIDQ
                     LSNRVKDLMVINRSTTELPLTVSYDKISLGRLRFWIHMQDAVYSLQQFGFSEKDADEL
                     KGIFVDTNLYLLALTFFVAAFHLLFDFLAFKSDISFWKKKKSMIGMSTKAVLWRCFST
                     VVIFLFLLDEQTSLLVLIPAGVGAAIELWKVKKALKITVAWRGLRPVFQFGTHSESER
                     KTEKYDAQAMKYLSYLLYPLCVGGAVYSLLNIKYKSWYSWLINSFVNGVYAFGFLFML
                     PQLFVNYKMKSVAHLPWKAFTYKAFNTFIDDVFAFIITMPTSHRLACFRDDVVFLVYL
                     YQRWLYPVDKSRVNEFGESYEEQPKRKPHPD"
     exon            399..499
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            500..689
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            690..838
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            839..917
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1035
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1130
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1215
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1319
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1385
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1436
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1519
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1554
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1610
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1655
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1656..1771
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..2378
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2324..2329
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /note="hexamer: AATAAA"
     polyA_site      2344
                     /gene="Clptm1l"
                     /gene_synonym="C130052I12Rik; Crr9; CRR9p"
                     /note="major polyA site"
ORIGIN      
        1 gtctggctcc cagagggccg tgcgcgtcca cttccgccag ctgctcggtt cccggaagcg
       61 gtggccggca aatccggcca atcccccagc gccgggtgtg ggttatcggg agcatgcggg
      121 gcggccggcg gcccgcgcga ggcgcgttgg tttccccgcg gcggtggcgg tggcgcgcag
      181 cggctctccc gtgagcggcg ggcggcggcg gcgctcggcc cgcaggttgc ggcgccatgt
      241 ggagcggccg cagctctttt accagcttgg tggtgggcgt gttcctggtg tacgtggtgc
      301 atacctgctg ggtcatgtac ggtatcgtct atacccgtcc gtgctcgggt gactccaact
      361 gcatccagcc ctatctggcc ctgcggccca aactgcagct gagtgtttac accaccacac
      421 ggtccagcct tggtgcagag aacaatgtgg acctgatctt gaacgtggaa gactttgatg
      481 tggattccaa atttgaaagg acagttaatg tttctgtacc aaagaaaaca agaaacaatg
      541 ggacgctgta tgcatatatt ttcctacatc atgctgggat tctaccctgg caagatggga
      601 aacaggtaca tgtggtcagt actctgacta cctacatgat ccccaaacca gaagaaatta
      661 acttgctcac tggggagtct gctacacagc aacagataga agccgagaag aagccatcaa
      721 acgccctgga tgaacccgtc tctcactggc gaccaaggct gaccctgaat gtgatggtgg
      781 atgactttgt ctttgatggt tcctccctgc ctgcagatgt gcatcggtac atgaagatga
      841 ttcagcttgg gaagacagtg cactacctcc ccatcctgtt cattgaccag ctgagcaacc
      901 gggtgaaaga cctgatggtg ataaaccgat ctaccaccga gctgccactc actgtgtcct
      961 acgacaagat ctcattgggg cggctgcgct tctggatcca catgcaggat gccgtgtact
     1021 ccctgcagca gttcgggttt tcagaaaaag atgcagatga attgaaggga attttcgtag
     1081 acaccaactt atatctctta gcattgacct tctttgttgc agcctttcac cttctttttg
     1141 atttcctggc atttaaaagt gacatcagtt tctggaagaa aaagaagagc atgattggaa
     1201 tgtctaccaa agcagtgctc tggcgttgct tcagcactgt ggtcatcttc ctcttcctgc
     1261 tggatgaaca gacaagcctg ctggtgctga tccctgcagg tgttggagct gccattgagc
     1321 tttggaaagt gaagaaggca ttgaaaatta cagtagcctg gaggggcttg agacctgtgt
     1381 ttcagtttgg tacccatagt gaatctgaga ggaagactga gaagtatgat gctcaggcca
     1441 tgaagtactt gtcttatctg ctctaccctc tctgtgtcgg gggcgctgtc tactcactcc
     1501 taaatatcaa gtataagagt tggtactcct ggctcatcaa cagctttgtg aatggtgtct
     1561 atgcctttgg cttcctcttc atgttgcccc agctttttgt caattacaag atgaagtcag
     1621 tggcacacct gccttggaag gcctttacct acaaggcttt taacaccttc attgatgatg
     1681 tctttgcctt catcatcacc atgcccacat cccaccggct ggcctgtttc agagatgatg
     1741 tggtcttcct ggtctacctt taccagcggt ggctttaccc tgtggataag agcagggtca
     1801 atgaatttgg ggagtcttat gaggagcagc ccaagcggaa gccccatcca gactgagcat
     1861 ctcggcccag gctcccaggc ggcactgtac tgcacagcac agttgggcca tgagtattcc
     1921 tgggggcttc gggaaaattc ctagatacca catcttctgc gttgccaaat ccctctgagc
     1981 atttctcagt atccctgagc accctctctt ctcgtgtttc agaaggaacc atagcactta
     2041 accatacacc ccacatgaac ttgggtcttg gtgattgtgc cagtgggcag tcacccaagg
     2101 gtagctctca gtgcatgagt gtcccatggc agccagtgga caccttagca cgcaagggta
     2161 gggagcatgg tggatttcca cgtcagcttg tccaagtgct ccttatgtgg atttcacata
     2221 cacaaaagtc gttctgtacg gactctggga tcaaatggct ctttttccct tttgtttaaa
     2281 atttgattgt ttaaagccta atgtatgtat gtttctattt taaaataaat ttctttggct
     2341 gtaatatttt tcttaacctc taataatata aaatatag
//
