LOCUS       NM_027085                799 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus chloride intracellular channel 3 (Clic3), mRNA.
ACCESSION   NM_027085
VERSION     NM_027085.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 799)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 799)
  AUTHORS   Naganuma,H., Miike,K., Ohmori,T., Tanigawa,S., Ichikawa,T.,
            Yamane,M., Eto,M., Niwa,H., Kobayashi,A. and Nishinakamura,R.
  TITLE     Molecular detection of maturation stages in the developing kidney
  JOURNAL   Dev Biol 470, 62-73 (2021)
   PUBMED   33197428
REFERENCE   3  (bases 1 to 799)
  AUTHORS   Butterfield,N.C., Curry,K.F., Steinberg,J., Dewhurst,H.,
            Komla-Ebri,D., Mannan,N.S., Adoum,A.T., Leitch,V.D., Logan,J.G.,
            Waung,J.A., Ghirardello,E., Southam,L., Youlten,S.E.,
            Wilkinson,J.M., McAninch,E.A., Vancollie,V.E., Kussy,F.,
            White,J.K., Lelliott,C.J., Adams,D.J., Jacques,R., Bianco,A.C.,
            Boyde,A., Zeggini,E., Croucher,P.I., Williams,G.R. and
            Bassett,J.H.D.
  TITLE     Accelerating functional gene discovery in osteoarthritis
  JOURNAL   Nat Commun 12 (1), 467 (2021)
   PUBMED   33473114
  REMARK    Erratum:[Nat Commun. 2021 May 28;12(1):3302. doi:
            10.1038/s41467-021-23768-8.. PMID: 34050183]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 799)
  AUTHORS   Lefebvre,J., Clarkson,M., Massa,F., Bradford,S.T., Charlet,A.,
            Buske,F., Lacas-Gervais,S., Schulz,H., Gimpel,C., Hata,Y.,
            Schaefer,F. and Schedl,A.
  TITLE     Alternatively spliced isoforms of WT1 control podocyte-specific
            gene expression
  JOURNAL   Kidney Int 88 (2), 321-331 (2015)
   PUBMED   25993318
REFERENCE   5  (bases 1 to 799)
  AUTHORS   Kim,K.H., Choi,B.K., Song,K.M., Cha,K.W., Kim,Y.H., Lee,H.,
            Han,I.S. and Kwon,B.S.
  TITLE     CRIg signals induce anti-intracellular bacterial phagosome activity
            in a chloride intracellular channel 3-dependent manner
  JOURNAL   Eur J Immunol 43 (3), 667-678 (2013)
   PUBMED   23280470
  REMARK    GeneRIF: CRIg signals induce anti-intracellular bacterial phagosome
            activity in a chloride intracellular channel 3-dependent manner.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL732557.4.
            
            On Apr 30, 2007 this sequence version replaced NM_027085.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009020.1, CB596015.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AL732557.4         129616-129687
            73-182              AL732557.4         130434-130543
            183-308             AL732557.4         130622-130747
            309-415             AL732557.4         130888-130994
            416-591             AL732557.4         131077-131252
            592-799             AL732557.4         131338-131545
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 17.27 cM"
     gene            1..799
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /note="chloride intracellular channel 3"
                     /db_xref="GeneID:69454"
                     /db_xref="MGI:MGI:1916704"
     exon            1..72
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..750
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /note="glutaredoxin-like oxidoreductase CLIC3"
                     /codon_start=1
                     /product="chloride intracellular channel protein 3"
                     /protein_id="NP_081361.1"
                     /db_xref="CCDS:CCDS15774.1"
                     /db_xref="GeneID:69454"
                     /db_xref="MGI:MGI:1916704"
                     /translation="MAETTKLQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTT
                     VDTRRALDVLKDFAPGSQLPILLYDGDVKTDTLQIEEFLEETLGPPDFPSLAPRYRES
                     NTAGNDIFHKFSAFIKNPVPTQDNALYQQLLRALTRLDSYLRAPLDHELAQEPHLRES
                     HRRFLDGDQFTLADCSLLPKLHIVDTVCAHFRQLPIPAELSCVRRYLDSALQKKEFKY
                     TCPHSAEILAAYQPAVHPR"
     exon            73..182
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            183..308
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            309..415
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            416..591
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            592..799
                     /gene="Clic3"
                     /gene_synonym="2300003G24Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggctgctgc tgccgccgga tgcctcggct cccaccatgg ctgaaaccac caagctccag
       61 ctctttgtga aggccagtga ggatggcgag agcgtaggac actgcccttc ctgtcagcgg
      121 ctcttcatgg tcctactcct caagggtgtg cccttcacac tcaccacagt ggacactcga
      181 agggcattgg atgtgctgaa ggacttcgca ccaggctcac agctgcccat cctgctgtac
      241 gatggggatg tcaagacaga cacactgcag atcgaggagt ttctggagga gacgttgggg
      301 ccacctgact tccctagcct ggcacccagg tacagggagt ccaacacagc gggcaatgac
      361 atcttccaca agttctctgc cttcatcaag aacccagtgc ctacacagga caatgccctg
      421 tatcagcagc tgctccgggc cctgaccagg ctggacagct acctgcgtgc accactggac
      481 cacgaactgg cacaggagcc acatcttcgt gagtcccacc gccgctttct cgatggtgac
      541 cagttcacgt tggctgactg cagtctacta cccaagctgc acattgtgga taccgtgtgt
      601 gcacacttcc gccagctgcc catccccgcg gaactgtcct gcgttcgtcg ctacttggac
      661 agtgcgttgc agaagaagga gttcaagtat acgtgtccac acagcgcaga gatcctggct
      721 gcctaccagc ctgctgtgca cccccgttag ccccactact tccatacact catctgcagc
      781 cccataaagc atctctgcc
//
