LOCUS       NM_199311               1592 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus C-type lectin domain family 4, member a1 (Clec4a1),
            mRNA.
ACCESSION   NM_199311 XM_194289
VERSION     NM_199311.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Hsu Y, Okada R, Nishimura T, Kawasaki N, Yamamoto K and Matsumoto
            N.
  TITLE     DCIR3 and DCIR4 are co-expressed on inflammatory and patrolling
            monocytes
  JOURNAL   Biochem Biophys Res Commun 494 (3-4), 440-445 (2017)
   PUBMED   29042196
  REMARK    GeneRIF: The anti- DCIR3 antibody established in this study,
            together with the previously established anti-DCIR1 and anti-DCIR4
            antibodies, would be a valuable tool to investigate biology and
            pathophysiology of monocytes.
REFERENCE   2  (bases 1 to 1592)
  AUTHORS   Kameda Y, Hanayama M, Kishimoto A, Kume M, Yamamoto K and Matsumoto
            N.
  TITLE     Dendritic cell inhibitory receptor 4 (DCIR4) is preferentially
            expressed on inflammatory and patrolling monocytes
  JOURNAL   Biochem Biophys Res Commun 480 (2), 215-221 (2016)
   PUBMED   27746174
  REMARK    GeneRIF: DCIR4 is preferentially expressed on the two major
            populations of monocytes: inflammatory and patrolling monocytes.
REFERENCE   3  (bases 1 to 1592)
  AUTHORS   Flornes LM, Bryceson YT, Spurkland A, Lorentzen JC, Dissen E and
            Fossum S.
  TITLE     Identification of lectin-like receptors expressed by antigen
            presenting cells and neutrophils and their mapping to a novel gene
            complex
  JOURNAL   Immunogenetics 56 (7), 506-517 (2004)
   PUBMED   15368084
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK626014.1 and BC049354.1.
            
            On Feb 23, 2011 this sequence version replaced NM_199311.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049354.1, BQ715169.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                CK626014.1         1-10
            11-1592             BC049354.1         1-1582
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 58.01 cM"
     gene            1..1592
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /note="C-type lectin domain family 4, member a1"
                     /db_xref="GeneID:269799"
                     /db_xref="MGI:MGI:3036291"
     exon            1..232
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..864
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /note="dendritic cell inhibitory receptor 4"
                     /codon_start=1
                     /product="C-type lectin domain family 4, member a1"
                     /protein_id="NP_955015.1"
                     /db_xref="CCDS:CCDS20507.1"
                     /db_xref="GeneID:269799"
                     /db_xref="MGI:MGI:3036291"
                     /translation="MALPNIYTDVNFKNQPVSSGLISDSSSCTVSDSSSALPKKTTIH
                     KSNPGFPRLLLALWIFFLLLAILFSVALIILFQMYSDLLEEKYTLERLNHARLHCVKN
                     HSSVEDKVWSCCPKNWKPFDSHCYFTSRDTASWSKSEEKCSLRGAHLLVIQSQEEQDF
                     ITNTLNPRAAYYVGLSDPKGHGQWQWVDQTPYDQNATSWHSDEPSGNTEFCVVLSYHP
                     NVKGWGWSVAPCDGDHRLICEMRQLYV"
     exon            233..346
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /inference="alignment:Splign:2.1.0"
     exon            347..448
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /inference="alignment:Splign:2.1.0"
     exon            449..600
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /inference="alignment:Splign:2.1.0"
     exon            601..716
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /inference="alignment:Splign:2.1.0"
     exon            717..1558
                     /gene="Clec4a1"
                     /gene_synonym="Dcir4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccattaag tgtctctgca ccttatcctg gatgctggat taatccttac catgtttatt
       61 tctcgtttat attaagtgta ttaagactga cacaggttct ctgaagaaag caggtctctt
      121 ctcaatatgg cattaccaaa catttatact gacgtgaact tcaaaaatca acctgtttcc
      181 tcaggcctca tctcagactc gtcttcatgt accgtctcag actcgtcttc agctctccca
      241 aagaagacca ctattcacaa aagtaaccct ggctttccca ggctgcttct tgccttgtgg
      301 atatttttcc tgctgttggc aatcttattc tctgttgctc tgatcatttt atttcaaatg
      361 tattctgatc tccttgaaga aaaatatact ctagaacgac tgaatcacgc aagattgcat
      421 tgtgtaaaaa accactcgtc tgtagaagac aaagtctgga gctgttgtcc aaagaattgg
      481 aagccatttg attcccactg ctacttcact tcccgtgaca ctgcatcctg gagtaagagt
      541 gaagagaagt gctccctcag gggtgctcat ctgctggtga tccagagcca ggaagagcag
      601 gatttcatca ccaacactct gaaccctcgt gctgcttatt atgtggggct gtcagatcca
      661 aagggccatg gacaatggca gtgggttgat cagacaccat atgatcaaaa tgccacatcc
      721 tggcactcag atgaacccag tggcaacact gaattttgtg ttgtgctaag ttatcatcca
      781 aacgttaaag gatggggctg gagtgtcgcc ccttgtgatg gtgatcatag gttgatttgt
      841 gagatgaggc agctctatgt atgaacgaag cattctctac agactcatga tgtgattgga
      901 atggaagctg taattataga gacagctagg aagttcttca tttgatcctc ttaggaatca
      961 aacagggact tggaattgta tcagaaagcc agattcttag atttctcttc tctcctcccc
     1021 tccctccctc ccttcccctt gccttcctct ctccccaacc cctaccccgt ttctttggag
     1081 acagggtttc actatgtacc tctggctgtc ctagaactca ctatatagac aagcctgacc
     1141 tcaaactcac agagatcctc ttgcctttat tttcctgagt gctggaatta aggacatgca
     1201 ctaccaccac cagtcagctt cttagtaaat tatgtgtaag agatgtctgc agaattttag
     1261 ataggtaagg aaccggtcct tccatttatg agagcatcag ctcacctttg tacacgttca
     1321 ttcatttcct cattcataaa gaaagtcttt tctccacacc agatgctatg ctagggaccc
     1381 cttagtgcac acacagaaag cacatgcatc tctctcctca cgcctgtctg tctgcagagg
     1441 ttttaagtca ctgattggat gatgtggttc tgccctccgt ctgctgtttg tcttctctct
     1501 ttggttttgc tgatgtagaa ccaacaaata aacgtttgtg ccctctgtgg tgatctgaaa
     1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
