LOCUS       NM_053165               2160 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus C-type lectin domain family 2, member h (Clec2h),
            mRNA.
ACCESSION   NM_053165
VERSION     NM_053165.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Zein,H.S., Abou-Samra,E., Scur,M., Gutsol,A., Hall,C.W.,
            Dasgupta,B., Gharibeh,L., Abujamel,T., Medina-Luna,D., Gamage,G.S.,
            Pelino,T.J., Nemer,M., Rahim,M.M.A., Steinle,A., Parsons,B.D. and
            Makrigiannis,A.P.
  TITLE     Clr-f expression regulates kidney immune and metabolic homeostasis
  JOURNAL   Sci Rep 12 (1), 4834 (2022)
   PUBMED   35318366
  REMARK    GeneRIF: Clr-f expression regulates kidney immune and metabolic
            homeostasis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2160)
  AUTHORS   Chen,P., Belanger,S., Aguilar,O.A., Zhang,Q., St-Laurent,A.,
            Rahim,M.M., Makrigiannis,A.P. and Carlyle,J.R.
  TITLE     Analysis of the mouse 129-strain Nkrp1-Clr gene cluster reveals
            conservation of genomic organization and functional receptor-ligand
            interactions despite significant allelic polymorphism
  JOURNAL   Immunogenetics 63 (10), 627-640 (2011)
   PUBMED   21667046
REFERENCE   3  (bases 1 to 2160)
  AUTHORS   Kveberg,L., Dai,K.Z., Inngjerdingen,M., Brooks,C.G., Fossum,S. and
            Vaage,J.T.
  TITLE     Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G
            receptors in rat and mouse
  JOURNAL   Immunogenetics 63 (7), 429-436 (2011)
   PUBMED   21409442
REFERENCE   4  (bases 1 to 2160)
  AUTHORS   Carlyle,J.R., Mesci,A., Ljutic,B., Belanger,S., Tai,L.H.,
            Rousselle,E., Troke,A.D., Proteau,M.F. and Makrigiannis,A.P.
  TITLE     Molecular and genetic basis for strain-dependent NK1.1
            alloreactivity of mouse NK cells
  JOURNAL   J Immunol 176 (12), 7511-7524 (2006)
   PUBMED   16751398
REFERENCE   5  (bases 1 to 2160)
  AUTHORS   Plougastel,B., Dubbelde,C. and Yokoyama,W.M.
  TITLE     Cloning of Clr, a new family of lectin-like genes localized between
            mouse Nkrp1a and Cd69
  JOURNAL   Immunogenetics 53 (3), 209-214 (2001)
   PUBMED   11398965
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB583062.1, AK090364.1 and AC132352.3.
            
            On Feb 23, 2011 this sequence version replaced NM_053165.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090364.1, BC021766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 BB583062.1         2-2
            2-940               AK090364.1         2-940
            941-2160            AC132352.3         52320-53539         c
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 63.07 cM"
     gene            1..2160
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /note="C-type lectin domain family 2, member h"
                     /db_xref="GeneID:94071"
                     /db_xref="MGI:MGI:2136934"
     exon            1..148
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..714
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /note="C-type lectin-related protein F"
                     /codon_start=1
                     /product="C-type lectin domain family 2 member H"
                     /protein_id="NP_444395.2"
                     /db_xref="CCDS:CCDS20576.1"
                     /db_xref="GeneID:94071"
                     /db_xref="MGI:MGI:2136934"
                     /translation="MNAAKVETSSMGMLQRADLTAADCLQEGEMGKKIQGKCFRIIST
                     VSPVKLYCCYGVIMVLTVAVIALSVALSVRNKIPAMEDREPCYTACPSGWIGFGSKCF
                     YFSEDMGNWTFSQSSCVASNSHLALFHSLEELNFLKRYKGTSDHWIGLHRASTQHPWI
                     WTDNTEYSNLVLTRGGGECGFLSDNGISSGRSYTHRKWICSKFVSSCKSRVGSVPRHV
                     "
     exon            149..274
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /inference="alignment:Splign:2.1.0"
     exon            275..459
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /inference="alignment:Splign:2.1.0"
     exon            460..566
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /inference="alignment:Splign:2.1.0"
     exon            567..2160
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1466..1471
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /note="hexamer: AATAAA"
     polyA_site      1487
                     /gene="Clec2h"
                     /gene_synonym="clr-f; Clrf"
                     /note="major polyA site"
ORIGIN      
        1 cctttcaaat cacctcctga attcagttga gtcatagttc ttcctctcag ctcacagatg
       61 aatgctgcaa aggttgaaac gagttccatg ggcatgctgc agagggcaga cctcactgct
      121 gcagactgcc tgcaggaggg agaaatgggt aaaaaaatcc aaggaaaatg tttcagaatc
      181 atctccactg tgtctcctgt taaactttac tgctgctatg gagtgatcat ggtcctcact
      241 gtagctgtaa ttgctctttc agttgctttg tcagtgagaa ataaaatccc agccatggaa
      301 gaccgtgaac cttgctacac cgcatgccca agtggctgga ttggatttgg aagtaaatgc
      361 ttttattttt ctgaagacat gggaaactgg accttcagtc agtcctcctg cgtagcatca
      421 aattcccatc tagcactgtt tcacagcctg gaggagctga attttctgaa gagatacaag
      481 gggacttctg accactggat tggcctgcac agagcatcaa cacagcaccc ttggatatgg
      541 acagacaaca ctgaatatag caacttggtt ctcacgagag gaggaggaga atgtggcttc
      601 ctgagtgata atgggatcag cagtggcagg agctacacac ataggaagtg gatttgtagc
      661 aagtttgtca gtagttgtaa atccagagta ggaagtgtac caaggcatgt gtgagaatca
      721 atcagatgct ctatgacctg ttatctacag ttggtgctct gctcctgatc aaccaaaacc
      781 attatcaaaa accaaaacca ttatcaaaat ccagcaataa tcacattgac agccaagatg
      841 aaaattagtt tagaggagtg ttgggcaccg gacaacctga gtaggagaca acctgagtcc
      901 cgccagagta ctggtgctct gggcggccat actcaggagt actgctgcaa actttcaacg
      961 tggccccggg tgggtgtctg gctgtgggaa gccagagaac cccagcccgc gggagttggg
     1021 gtgtgtggac aagtggcatt ccgaggtctc tgagcctcat ggatgccaga gataacaggt
     1081 tctccgtctc gagcatccca gacaccgttg gacactgtga aagagctaag gacaaagtgg
     1141 gagcccaggg ggcagcttgg acaatttttc ctgatctgaa aagaatctag taaagagtaa
     1201 aattcaaatg gcatacacac gtatggaatt ctcaaaaaag atgagactct cgcctcgccc
     1261 cctgctgtct cctccctttg gtcctgggga tggccaagca ctatttattg atattgatct
     1321 tacttcctgt gctaagcaca ttattttgag aaatgttttg cagttcttat caagtttagt
     1381 gtatctggtt ttatactgaa gtctttggtc catgtcgaac taagtttggt acagagtgat
     1441 aagtatgata tatttgcatt tttctaataa agacagtttg aagatcagtt tcaccagttt
     1501 catttgttga agatgctggc tttttatctg gtgtgtattt atagattctt tatcaaacat
     1561 caagtgtcca ggggctggag actctgctgt taagagcatt ggctgctctt ccagaggaac
     1621 acagttcagt tcccagcacc catgtggcag ctcacatcta tttgtaactc tagctccagg
     1681 agattgacac tgtaacacag acacacatac aggtaaaaca tcagtgcaca gaactggaga
     1741 gacgactcag tggttaagag cactgactgc tcttccagag gtcctgagtt caattcctac
     1801 caaccacata aaatgaggat cctatgtcct cttctggtat gtctgaagac agcaacagtg
     1861 tactcacata cattaaataa ataaataaat aaataaataa ataaataaat aaataaatgg
     1921 atggatctta gatgaccaca ggaggaggga cactgaacca aggttatcta ctgtcccaaa
     1981 aaattaaaat caatgcacat aaaaataaat ccttaaaaaa atgtgagatg tccataagca
     2041 tgtagactta catttctgtc attaatatga ttctgatgct cagcaggttt gctttttggt
     2101 tttgttttaa cactgtgctg tttgcatcac tatacctttg taataaaatc tgagatcaca
//
