LOCUS       NM_001418965             795 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus claudin domain containing 2 (Cldnd2), transcript
            variant 2, mRNA.
ACCESSION   NM_001418965 XM_017312350
VERSION     NM_001418965.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149091.3 and AC154108.3.
            
            On Mar 24, 2023 this sequence version replaced XM_017312350.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.291365.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                AC149091.3         240652-240709
            59-163              AC154108.3         203412-203516       c
            164-345             AC154108.3         203088-203269       c
            346-486             AC154108.3         202596-202736       c
            487-577             AC154108.3         201961-202051       c
            578-795             AC154108.3         201468-201685       c
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.25 cM"
     gene            1..795
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /note="claudin domain containing 2"
                     /db_xref="GeneID:74276"
                     /db_xref="MGI:MGI:1921526"
     exon            1..58
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            59..163
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            164..345
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..779
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     claudin domain-containing protein 2"
                     /codon_start=1
                     /product="claudin domain-containing protein 2 isoform 2"
                     /protein_id="NP_001405894.1"
                     /db_xref="GeneID:74276"
                     /db_xref="MGI:MGI:1921526"
                     /translation="MGVKKSLQTGGNLLNLLSSILTVLSTTTNYWTRQQGGHSGLWQE
                     CTHGKCSNIPCQNTVAVSAACMVLAATFSIVALGIGIRIQCREAESRRSQNTIVLLFL
                     SGLLLLIALAVYTSKNAWKPEVFFSWSYFFGWLLLSACRHDLAEHRSHQRIPGMPMNA
                     ACLGQNKGMAFSLAPACFSAERRDRSLETTETRIKWLVES"
     exon            346..486
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            487..577
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            578..795
                     /gene="Cldnd2"
                     /gene_synonym="1700071E18Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagaaccat cctcccttcc cccaaccccg cgggctcttt gtcgcagggg accaggctgc
       61 tctcacactg tagtctgcct ggcccagaac tcattacatt actcatggcc tgcccttggg
      121 cttgtgatgt cttgcctcag cctcactgag gctaggatcc cagctgcctc cttggcatgg
      181 gggtgaagaa gagccttcag actggaggga atttacttaa tctcttgagc agcatcctca
      241 cagtactgtc tactaccacc aactactgga cccgacagca aggggggcac agtggcctat
      301 ggcaggagtg tacccatggc aaatgctcca acatcccctg ccagaacacc gtggcagtgt
      361 ccgcagcgtg catggtgttg gcagcaacct tcagtattgt agctttgggg atcgggataa
      421 ggattcagtg tcgagaggca gagtcacgac gtagccagaa taccattgtc ttacttttcc
      481 tcagcgggtt gctgctgctg attgccttgg ccgtatacac ttcaaagaat gcctggaagc
      541 cagaagtctt cttctcctgg tcctactttt tcggatggct tctgctttct gcttgccgac
      601 atgatcttgc agagcaccga agccatcagc ggattcccgg tatgcctatg aatgcggcct
      661 gcctggggca gaataaagga atggctttta gcctcgcccc tgcgtgcttt tctgcggaac
      721 gtagagacag aagcttggag actacagaga cacggataaa gtggcttgta gagagttaag
      781 gaggtcagaa ggaat
//
