LOCUS       NM_001384265             786 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus claudin 25 (Cldn25), mRNA.
ACCESSION   NM_001384265
VERSION     NM_001384265.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Tanaka H, Yamamoto Y, Kashihara H, Yamazaki Y, Tani K, Fujiyoshi Y,
            Mineta K, Takeuchi K, Tamura A and Tsukita S.
  TITLE     Claudin-21 Has a Paracellular Channel Role at Tight Junctions
  JOURNAL   Mol Cell Biol 36 (6), 954-964 (2016)
   PUBMED   26729464
  REMARK    GeneRIF: Claudin-21, which is more highly expressed in the
            embryonic than the postnatal stages, acts as a paracellular channel
            for small cations, such as Na(+), similar to the typical
            channel-type claudins claudin-2 and -15.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  AUTHORS   Mineta K, Yamamoto Y, Yamazaki Y, Tanaka H, Tada Y, Saito K, Tamura
            A, Igarashi M, Endo T, Takeuchi K and Tsukita S.
  TITLE     Predicted expansion of the claudin multigene family
  JOURNAL   FEBS Lett 585 (4), 606-612 (2011)
   PUBMED   21276448
REFERENCE   3  (bases 1 to 786)
  AUTHORS   Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J and Blasig
            IE.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim Biophys Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160137.2.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-786               AC160137.2         175577-176362       c
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 26.58 cM"
     gene            1..786
                     /gene="Cldn25"
                     /gene_synonym="Cldn21; Cldn21-ps; Cldn25-ps; Gm16492;
                     Gm513"
                     /note="claudin 25"
                     /db_xref="GeneID:100042785"
                     /db_xref="MGI:MGI:3642767"
     exon            1..786
                     /gene="Cldn25"
                     /gene_synonym="Cldn21; Cldn21-ps; Cldn25-ps; Gm16492;
                     Gm513"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..741
                     /gene="Cldn25"
                     /gene_synonym="Cldn21; Cldn21-ps; Cldn25-ps; Gm16492;
                     Gm513"
                     /note="claudin 21, pseudogene; claudin 25, pseudogene"
                     /codon_start=1
                     /product="putative claudin-25"
                     /protein_id="NP_001371194.1"
                     /db_xref="GeneID:100042785"
                     /db_xref="MGI:MGI:3642767"
                     /translation="MACSFRGRVQLGGLLLSVLGWVCSCVTTVLPQWKTLTLDLNEME
                     TWVSGLWEACVNQEEAGTVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLSSCGL
                     ECFRFHRPGGVFKTRLCLLGGTLEASASATTLFPVSWVAYATFQDFWDDSIPEIVPRW
                     EFGDALFLGWAAGLFLAVGGLLLIFSACLENEDGSSSWMADATAPQACAPVEEEFDGS
                     FHLTPRPVNQVI"
ORIGIN      
        1 gctgaccagt ccctgagctc attatcccct cctccagagg gcacaaccat ggcctgtagc
       61 ttccgtggga gagtccagct tggaggtctg ctcctctctg tccttggctg ggtgtgctcc
      121 tgtgtcacca ccgttcttcc ccagtggaag actctcactc tggatctgaa tgaaatggaa
      181 acctgggtct cgggactctg ggaggcatgc gtgaatcagg aggaagctgg cactgtatgc
      241 aaagccttcg agtcgttttt gtctctgccc caagagctac aggtagcccg aattctcatg
      301 gtggcttccc atgggctggg actattggga cttctgctgt ctagctgcgg gttggaatgc
      361 ttccggtttc acaggcctgg aggagttttc aagactcggc tgtgcctcct gggagggact
      421 ctggaagcat cagcttcagc tactaccctc tttccagtct cctgggtggc ctatgccaca
      481 tttcaagact tctgggatga cagcatccct gagattgtgc cccggtggga gtttggagac
      541 gccttgttcc tgggctgggc tgctgggctt ttcctagctg tgggtggact cctcctcatc
      601 ttttcagctt gcctggaaaa tgaagatgga tcttcttcct ggatggctga tgccacggcc
      661 ccacaagcct gtgctccagt agaggaagaa tttgatggtt ccttccatct cacaccaaga
      721 ccggtgaacc aggtcatcta gagctacagt ctgcctagga ctctctataa taaaggaatg
      781 ccagta
//
