LOCUS       NM_001114347            6369 bp    mRNA    linear   ROD 08-AUG-2024
DEFINITION  Mus musculus CLIP associating protein 2 (Clasp2), transcript
            variant 3, mRNA.
ACCESSION   NM_001114347
VERSION     NM_001114347.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6369)
  AUTHORS   Sasner,M., Preuss,C., Pandey,R.S., Uyar,A., Garceau,D.,
            Kotredes,K.P., Williams,H., Oblak,A.L., Lin,P.B., Perkins,B.,
            Soni,D., Ingraham,C., Lee-Gosselin,A., Lamb,B.T., Howell,G.R. and
            Carter,G.W.
  TITLE     In vivo validation of late-onset Alzheimer's disease genetic risk
            factors
  JOURNAL   Alzheimers Dement 20 (7), 4970-4984 (2024)
   PUBMED   38687251
REFERENCE   2  (bases 1 to 6369)
  AUTHORS   Klaus,A., Clapes,T., Yvernogeau,L., Basu,S., Weijts,B., Maas,J.,
            Smal,I., Galjart,N. and Robin,C.
  TITLE     CLASP2 safeguards hematopoietic stem cell properties during mouse
            and fish development
  JOURNAL   Cell Rep 39 (11), 110957 (2022)
   PUBMED   35705037
  REMARK    GeneRIF: CLASP2 safeguards hematopoietic stem cell properties
            during mouse and fish development.
REFERENCE   3  (bases 1 to 6369)
  AUTHORS   Marchal,G.A., Jouni,M., Chiang,D.Y., Perez-Hernandez,M.,
            Podliesna,S., Yu,N., Casini,S., Potet,F., Veerman,C.C., Klerk,M.,
            Lodder,E.M., Mengarelli,I., Guan,K., Vanoye,C.G., Rothenberg,E.,
            Charpentier,F., Redon,R., George,A.L. Jr., Verkerk,A.O.,
            Bezzina,C.R., MacRae,C.A., Burridge,P.W., Delmar,M., Galjart,N.,
            Portero,V. and Remme,C.A.
  TITLE     Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at
            Intercalated Discs
  JOURNAL   Circ Res 129 (3), 349-365 (2021)
   PUBMED   34092082
  REMARK    GeneRIF: Targeting the Microtubule EB1-CLASP2 Complex Modulates
            NaV1.5 at Intercalated Discs.
REFERENCE   4  (bases 1 to 6369)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6369)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   6  (bases 1 to 6369)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   7  (bases 1 to 6369)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 6369)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
REFERENCE   9  (bases 1 to 6369)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   10 (bases 1 to 6369)
  AUTHORS   Akhmanova,A., Hoogenraad,C.C., Drabek,K., Stepanova,T.,
            Dortland,B., Verkerk,T., Vermeulen,W., Burgering,B.M., De
            Zeeuw,C.I., Grosveld,F. and Galjart,N.
  TITLE     Clasps are CLIP-115 and -170 associating proteins involved in the
            regional regulation of microtubule dynamics in motile fibroblasts
  JOURNAL   Cell 104 (6), 923-935 (2001)
   PUBMED   11290329
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC167246.2 and AC107803.15.
            
            Transcript Variant: This variant (3) represents the longest
            transcript and encodes the longest isoform (c).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-403               AC167246.2         130669-131071
            404-482             AC167246.2         150786-150864
            483-586             AC167246.2         155764-155867
            587-678             AC167246.2         159393-159484
            679-754             AC107803.15        30017-30092
            755-852             AC107803.15        31914-32011
            853-923             AC107803.15        44798-44868
            924-1070            AC107803.15        71376-71522
            1071-1150           AC107803.15        93409-93488
            1151-1243           AC107803.15        99793-99885
            1244-1389           AC107803.15        102308-102453
            1390-1525           AC107803.15        105937-106072
            1526-1596           AC107803.15        106715-106785
            1597-1656           AC107803.15        108357-108416
            1657-1734           AC107803.15        110057-110134
            1735-1902           AC107803.15        110857-111024
            1903-1958           AC107803.15        111583-111638
            1959-2132           AC107803.15        112407-112580
            2133-2156           AC107803.15        116815-116838
            2157-2174           AC107803.15        118354-118371
            2175-2276           AC107803.15        120420-120521
            2277-2447           AC107803.15        126782-126952
            2448-2555           AC107803.15        128857-128964
            2556-2662           AC107803.15        134478-134584
            2663-2686           AC107803.15        136984-137007
            2687-2931           AC107803.15        138176-138420
            2932-2995           AC107803.15        139922-139985
            2996-2998           AC107803.15        145279-145281
            2999-3162           AC107803.15        148192-148355
            3163-3241           AC107803.15        150631-150709
            3242-3385           AC107803.15        154876-155019
            3386-3529           AC107803.15        157690-157833
            3530-3636           AC107803.15        159725-159831
            3637-3790           AC107803.15        162076-162229
            3791-4019           AC107803.15        164231-164459
            4020-4213           AC107803.15        166921-167114
            4214-4342           AC107803.15        167650-167778
            4343-4549           AC107803.15        169644-169850
            4550-4666           AC107803.15        173372-173488
            4667-6369           AC107803.15        176229-177931
FEATURES             Location/Qualifiers
     source          1..6369
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 64.06 cM"
     gene            1..6369
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /note="CLIP associating protein 2"
                     /db_xref="GeneID:76499"
                     /db_xref="MGI:MGI:1923749"
     exon            1..403
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..4753
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /note="isoform c is encoded by transcript variant 3;
                     CLIP-associating protein CLASP2; cytoplasmic
                     linker-associated protein 2; CLASP2alpha; CLASP2gamma"
                     /codon_start=1
                     /product="CLIP-associating protein 2 isoform c"
                     /protein_id="NP_001107819.1"
                     /db_xref="GeneID:76499"
                     /db_xref="MGI:MGI:1923749"
                     /translation="MEPRGAEYFCAQVLQKDVSGRLQAGEELLLCLGTPGAIPDLEDD
                     PSRLAKTVDALTRWVGSSNYRVSLLGLEILSAFVDRLSTRFKSYVTMVTTALIDRMGD
                     VKDKVREEAQNLTLKLMDEVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGT
                     QPLVISKLVPHLCVLFGDSNSQVRNAALSAVVEIYRHVGEKLRIDLCKRDIPPARLEM
                     VLAKFDEVQNSGGMILSVCKDKSFDDEESVDGNRPSSAASAFKVPAPKTPGNPVSSAR
                     KPGSAGGPKVGGPSKEGGAGAVDEDDFIKAFTDVPSVQIYSSRELEETLNKIREILSD
                     DKHDWDQRANALKKIRSLLVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACIT
                     VAHLSTVLGNKFDHGAEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLI
                     TSNCTSKSVPVRRRSFEFLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEAR
                     KTYMGLRNHFPGEAETLYNSLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNR
                     PFSSKWSTANPSTVAGRVSVGGSKANPLPGSLQRSRSDIDVNAAAGAKAHHAAGQAVR
                     SGRLGAGALNPGSYASLEDTSDKMDGTASDDGRVRAKLSTPLVAVGNAKTDSRGRSRT
                     KMVSQSQPGSRSGSPGRVLTTTALSTVSSGAQRVLVNSASAQKRSKIPRSQGCSREAS
                     PSRLSVARSSRIPRPSVSQGCSREASRESSRDTSPVRSFQPLGPGYGISQSSRLSSSV
                     SAMRVLNTGSDVEEAVADALLLGDIRTKKKPARRRYESYGMHSDDDANSDASSACSER
                     SYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRVELKR
                     LCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFVLLTQLLKKMGADLLGS
                     VQAKVQKALDITRESFPNDLQFNILMRFTVDQTQTPSLKVKVAILKYIETLAKQMDPR
                     DFTNSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQ
                     DGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTSQNTLSPSAFD
                     YDTENMNSEDIYSSLRGVTEAIQNFSFRSQEDMSEPVRRDPKKEDGDTICSGPGMSDP
                     RAGGDAADGSQPALDNKASLLHSMPLHSSPRSRDYNPYNYSDSISPFNKSALKEAMFD
                     DDADQFPDDLSLDHSDLVAELLKELSNHNERIEERKIALYELMKLTQEESFSVWDEHF
                     KTILLLLLETLGDKEPTIRALALKVLKEILRHQPARFKNYAELTVMKTLEAHKDPHKE
                     VVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNM
                     LLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYI
                     KRAQTGSAGADPTADVSGQS"
     exon            404..482
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            483..586
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            587..678
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            679..754
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            755..852
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            853..923
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1070
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1150
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1243
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1389
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1525
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1596
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1656
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1734
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1902
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..1958
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            1959..2132
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2156
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2174
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2175..2276
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2447
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2555
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2556..2662
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2663..2686
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2687..2931
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..2995
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..2998
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            2999..3162
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3241
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            3242..3385
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            3386..3529
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            3530..3636
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            3637..3790
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            3791..4019
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            4020..4213
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            4214..4342
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            4343..4549
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            4550..4666
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     exon            4667..6369
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6334..6339
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /note="hexamer: AATAAA"
     polyA_site      6369
                     /gene="Clasp2"
                     /gene_synonym="1500004F14Rik; 8030404L10Rik; CLASP2beta;
                     mKIAA0627"
                     /note="major polyA site"
ORIGIN      
        1 gccgcagcct ctgaagcggg gctgggaccg gggggcgccg agtttgatta gtttaggggg
       61 gccgtccccc gccggccgcc gcaccccagg cagcggcgtc tctgcgtgtc ggcgcgtccc
      121 ggaggcttca ccgccgcgcc tcggcggtgc tgcgaggaaa gttggcgtgt aaggggcgac
      181 gggcgtgtga ggggtggcgg gcgcggccat ggagccccgc ggcgccgagt acttctgcgc
      241 ccaagtgctg cagaaggacg tgagcggccg gctgcaggcg ggcgaggagc tgctgctctg
      301 cctcggcacg cccggagcca tcccggacct ggaggacgat ccgagccgcc tggctaagac
      361 cgtggacgcg ctcacccgct gggtgggctc gagcaactac cgggtatcgt tgttaggatt
      421 ggagatttta agtgcctttg tggatagatt gtcaacacga ttcaaatctt atgtaacaat
      481 ggttaccaca gctttaatag acagaatggg agatgtcaaa gacaaagttc gagaagaagc
      541 tcagaacctg acactgaagc tgatggatga ggtggcgccg cctatgtaca tctgggagca
      601 gctagcttct ggcttcaagc acaagaactt tcgatctcga gaaggcgtgt gcctgtgtct
      661 tattgagacc ttgaacatct ttgggactca accactggtc atcagcaagt tggtgccgca
      721 tttatgtgtc ttatttggag actctaacag tcaggtgaga aatgctgcac tatcagctgt
      781 agtggagatt tatagacacg taggagagaa gctgaggatt gatttgtgta aaagagacat
      841 tccccctgct agattagaaa tggtacttgc caaatttgat gaagttcaga attctggcgg
      901 tatgattttg agcgtctgca aagataaaag ctttgatgat gaggaatcag tggatggaaa
      961 taggccgtcg tcagctgctt cagccttcaa ggttcctgca cctaaaacac ctgggaatcc
     1021 tgtcagcagt gcaagaaagc ctggctcagc aggtggccct aaggttggag gtccttctaa
     1081 agaaggaggg gctggagcag ttgatgaaga tgactttata aaagctttta cagatgttcc
     1141 ttctgttcag atctattcta gtcgagaact tgaagagacg ttaaataaga tcagggaaat
     1201 tttgtcagat gacaaacatg actgggacca gcgtgccaat gcgcttaaga aaatcagatc
     1261 actgcttgtt gctggagccg cacagtatga ttgctttttc cagcacctac gtttgttgga
     1321 tggagcgctt aagctgtcag ctaaggacct cagatcccag gtggtcaggg aagcttgcat
     1381 cactgttgct cacctttcaa cagtcttggg aaacaaattt gatcacggcg ctgaagccat
     1441 cgtccctacg ctttttaatc ttgtccccaa tagtgccaaa gtcatggcga cctctggatg
     1501 tgcagcaatc agatttatta ttcggcatac ccatgtacct agacttattc ctttaataac
     1561 aagcaactgc acatcaaagt cagttcctgt aaggagacgt tcatttgaat ttttagattt
     1621 gctgctgcaa gaatggcaga ctcattcact ggaaagacat gcagctgttt tggttgaaac
     1681 gattaagaag ggcattcatg atgctgatgc tgaggccaga gtggaggcaa ggaagacata
     1741 catgggcctt aggaaccact ttcctggtga agctgaaaca ttgtacaact cccttgagcc
     1801 atcatatcag aaaagtcttc aaacttactt aaagagttct ggaagtgtag cttctcttcc
     1861 gcagtcagac aggtcctcat ccagctcaca agaaagtctc aatcgtcctt tttcttctaa
     1921 atggtcaaca gcaaatcctt caactgtagc tggaagagta tctgtgggag gcagcaaagc
     1981 caaccccctt ccaggaagcc tgcagcgttc tcgaagtgac attgatgtga atgcggcagc
     2041 tggtgccaag gctcatcatg ctgctgggca ggcggtgcga agtgggcgct taggtgcagg
     2101 tgccctgaac ccaggctcct atgcatcact agaggatact tctgacaaga tggatggaac
     2161 agcatctgat gatggtcggg tgagagccaa gctttctaca ccgcttgttg ctgtgggaaa
     2221 tgccaagacc gactctagag ggagaagccg gacaaaaatg gtgtctcagt cccagcctgg
     2281 cagccgatct gggtctccag gaagagttct aaccacaaca gccctctcta ctgtgagctc
     2341 tggtgctcaa cgagtcctgg tcaattcagc ttcagcacag aagagaagca agatcccaag
     2401 gagccagggc tgcagcagag aggccagccc atctcggctc tcagtggccc ggagcagccg
     2461 tattcctcgg ccgagtgtga gtcaaggctg tagccgggaa gccagcagag agagcagcag
     2521 ggacacgagt ccggtgcgct ccttccagcc gctgggtccg ggatatggga tcagccagtc
     2581 cagccggttg tcgtcctctg tcagtgccat gcgagtccta aacacaggct ccgatgtgga
     2641 ggaggcagta gctgatgccc tgctcttagg agacatacgg actaagaaaa aacctgctcg
     2701 aagaaggtat gaatcatatg gaatgcactc agatgatgat gccaacagcg atgcctctag
     2761 tgcgtgttca gaacgctcct atagctctcg aaatggtagt attcctacct acatgagaca
     2821 gacagaagac gtggcagaag tcctcaacag atgtgctagc tccaattggt cagagaggaa
     2881 agaaggcctc ttgggtctgc agaacttgtt aaaaaaccag agaacgctaa gtcgagttga
     2941 actgaaaaga ttatgtgaaa ttttcacaag aatgtttgca gatcctcatg gcaagagagt
     3001 gttcagcatg ttcttggaga ctctagtaga tttcatacaa gtccacaaag atgatcttca
     3061 agattggttg tttgttctgc tgacacagct gctgaaaaaa atgggtgctg atttgcttgg
     3121 ctctgttcag gcaaaagttc agaaagccct tgatattaca agagagtctt ttccaaatga
     3181 tcttcagttt aatatcctaa tgagatttac agttgaccag acccaaacgc caagcttgaa
     3241 ggtaaaggtg gctatcctta agtacataga aactctggca aagcagatgg acccaagaga
     3301 ttttacaaat tccagtgaaa ctcgcctggc agtgtctcgg gtcatcactt ggacgacaga
     3361 gcccaaaagc tctgatgttc ggaaggcagc gcagtcagtg ctgatttctt tatttgaact
     3421 caatacccca gagtttacaa tgttactagg agctttacca aaaactttcc aggatggtgc
     3481 tactaaactt cttcacaatc acctccggaa cactggcaat ggcacccaga gttccatggg
     3541 gagtcctttg acgagaccaa cacctcggtc accagccaac tggtccagtc ctcttacttc
     3601 tcctaccaac acgtctcaga atacgttatc tccaagtgca tttgattacg atacagagaa
     3661 catgaattct gaagacattt atagctccct tagaggcgtc actgaggcaa tccagaattt
     3721 cagcttcaga agccaagaag atatgagtga gccagtgagg agggacccta aaaaggagga
     3781 tggtgacaca atatgtagtg gtcctgggat gtcagatcca agagcaggag gtgatgctgc
     3841 tgacggcagc cagccagctc tggataataa agcatcgttg ctccactcaa tgccactcca
     3901 ctcctctcca cgctcccgtg actataaccc atataactac tcagatagca tcagtccttt
     3961 caacaagtct gccctcaagg aagccatgtt tgatgatgac gccgaccaat ttcctgatga
     4021 tctttcctta gaccattctg acctagttgc agagttgttg aaggagctgt ctaatcataa
     4081 tgaacgtata gaagaaagaa aaattgccct gtatgaactc atgaagctaa cccaggaaga
     4141 atctttcagt gtttgggatg aacacttcaa aacaatatta ttgttattgc ttgagaccct
     4201 tggggataaa gagcctacaa tccgggcctt ggcattaaaa gttttaaaag aaatcttaag
     4261 gcatcaacca gcaagattca aaaactatgc agaactaact gtcatgaaaa cactggaagc
     4321 acataaagat cctcacaaag aggtggtgag atctgctgag gaagctgcct ccgtattggc
     4381 tacttccatt agtccagagc agtgcatcaa agtgctttgt cccatcatac aaaccgctga
     4441 ctaccctatt aatctggctg caatcaaaat gcaaacaaaa gtgatagaga gagtatccaa
     4501 ggagaccctt aacatgctct taccagagat catgccgggt ctaatacagg gttatgataa
     4561 ttcagaaagc agtgtccgga aagcttgtgt cttctgcctg gtggctgtcc atgcagtgat
     4621 tggtgatgaa ctaaagccac atctcagtca actcactggt agtaaaatga agctgctgaa
     4681 cctttacatc aagcgtgcac agacgggctc tgcaggcgcg gaccccactg ctgatgtttc
     4741 tggacagagt tagtgctgcc gacggcgcct cccagtctct gagaggacaa ctggctgccc
     4801 tcctcaagga aaggacactc aagtacagct ttgggactca gctgcggttt cccaggtcta
     4861 gcttttcgtt ttgttctgtt ttgtattttc tgtaacagag gggtgtcctc agtctgcatg
     4921 taactttatg atagttattc caagttcagg agaagcagta ttaacatcag ttgatcagta
     4981 caaagtaatt ttttaatcta attcaccatt tcacatgttt gtacttcttt gtcttcccat
     5041 taacctttgc cagtgttatg attgtataca tttttaaaaa tgctggttaa acaggaatgc
     5101 ttaaagcttt aaaagtttta acagtctaaa ctttgttttg ccttcattca actgcagaag
     5161 aatattttta ttgttacttt tgttctgtat catgtcctat gctagaaata ctgacaataa
     5221 tgtgagacaa agcagggcta cgtggcactc cagccagact ctgtggatgt gcgctgatgc
     5281 tcgtcatcag cagcaactcc tttgggatga cctcaatgag aaatgtcatg gaaccagcca
     5341 gttctgtaag actgacgata gtgtctgtcg gttcttgatc ttgccacctt tatttaaagc
     5401 cgtgtccctt cttttacccc gtaagaaagc tgcaccagat cacctgccta ggtttccatg
     5461 agaattatta caatgggagg ttttgttgca gagccttttg gtttatcttt gttgtgaatg
     5521 atgctttttg ttgtatttat taatatcaaa ttcacttatg aatagacttg ataatggaaa
     5581 cagatgagaa aaatcaagtg catgtgtgtc tttgactatt ctgtttctca tttgataaac
     5641 taattattga catgggagtc aaccagcacc tttttgttga atggtggaac ctggtttcct
     5701 ttgaccatga aattgtcttc tggaaacatg ggtcctgatg agagagaaga tgctgcaaga
     5761 ggcttctgtc cattgggctc tcactctacc tctcagggct gacattttaa ctgacccgct
     5821 tcctggagtg tcttgtcttg gaaaactact tcaaaggaga tgttttgtta ccttttaaca
     5881 tttttttaaa tcacctctgc taaagttatt ttcgtgtgca gccaactttc aaatattacc
     5941 agtttgggtg aaaggccaaa tttggtgatt tggaaccagg atactattga tttctcatct
     6001 tgactttttt tttttttttt tttttttttt aaatcctaac ataagatgaa tttgactgga
     6061 aagcaaatgg ctgttaggga agcagtttgc tattgttaca gagttaccta tactttgttc
     6121 agctggaaaa atgtagaaat gtatgtaaag aaagtaagcc gagaaaactg gatggatgat
     6181 tggtcatagg ctttttcttt cctttgtttt tccgttttag cagcaagaag agatattact
     6241 ccacaccctc tccctactgt aacagttttg ttttctactg ttaatgacat tgtgtattta
     6301 tagctctatg cttactgttg tgcatatact ggcaataaaa ctgtacataa cattacttga
     6361 agaccttaa
//
