LOCUS       NM_016904                757 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus CDC28 protein kinase 1b (Cks1b), mRNA.
ACCESSION   NM_016904
VERSION     NM_016904.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Wan,L., Hu,X., Xia,T., Li,F., Chi,Q., Ma,H., Yan,S., Li,W. and
            Huang,W.
  TITLE     Disruption of Cdyl gene impairs mouse lung epithelium
            differentiation and maturation
  JOURNAL   Gene 853, 147088 (2023)
   PUBMED   36464171
REFERENCE   2  (bases 1 to 757)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 757)
  AUTHORS   Ellederova,Z., Del Rincon,S., Koncicka,M., Susor,A., Kubelka,M.,
            Sun,D. and Spruck,C.
  TITLE     CKS1 Germ Line Exclusion Is Essential for the Transition from
            Meiosis to Early Embryonic Development
  JOURNAL   Mol Cell Biol 39 (13), e00590-18 (2019)
   PUBMED   30988159
  REMARK    GeneRIF: Data revealed that CKS1 could compensate for CKS2 in
            mammalian meiosis in vivo but that its expression in the germ line
            is deleterious for early embryonic development.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 757)
  AUTHORS   Sora,R.P., Ikeda,M. and Longnecker,R.
  TITLE     Two Pathways of p27Kip1 Degradation Are Required for Murine
            Lymphoma Driven by Myc and EBV Latent Membrane Protein 2A
  JOURNAL   mBio 10 (2), e00548-19 (2019)
   PUBMED   30992353
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 757)
  AUTHORS   Fish,K., Sora,R.P., Schaller,S.J., Longnecker,R. and Ikeda,M.
  TITLE     EBV latent membrane protein 2A orchestrates p27kip1 degradation via
            Cks1 to accelerate MYC-driven lymphoma in mice
  JOURNAL   Blood 130 (23), 2516-2526 (2017)
   PUBMED   29074502
REFERENCE   6  (bases 1 to 757)
  AUTHORS   Aleem,E., Kiyokawa,H. and Kaldis,P.
  TITLE     Cdc2-cyclin E complexes regulate the G1/S phase transition
  JOURNAL   Nat Cell Biol 7 (8), 831-836 (2005)
   PUBMED   16007079
REFERENCE   7  (bases 1 to 757)
  AUTHORS   Zhang,Y., Lin,Y., Bowles,C. and Wang,F.
  TITLE     Direct cell cycle regulation by the fibroblast growth factor
            receptor (FGFR) kinase through phosphorylation-dependent release of
            Cks1 from FGFR substrate 2
  JOURNAL   J Biol Chem 279 (53), 55348-55354 (2004)
   PUBMED   15513912
  REMARK    GeneRIF: FGFR kinase regulates the cell cycle through
            phosphorylation-dependent release of Cks1 from FGFR substrate 2
REFERENCE   8  (bases 1 to 757)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 757)
  AUTHORS   Fowles,L.F., Bennetts,J.S., Berkman,J.L., Williams,E., Koopman,P.,
            Teasdale,R.D. and Wicking,C.
  TITLE     Genomic screen for genes involved in mammalian craniofacial
            development
  JOURNAL   Genesis 35 (2), 73-87 (2003)
   PUBMED   12533789
REFERENCE   10 (bases 1 to 757)
  AUTHORS   Spruck,C., Strohmaier,H., Watson,M., Smith,A.P., Ryan,A., Krek,T.W.
            and Reed,S.I.
  TITLE     A CDK-independent function of mammalian Cks1: targeting of
            SCF(Skp2) to the CDK inhibitor p27Kip1
  JOURNAL   Mol Cell 7 (3), 639-650 (2001)
   PUBMED   11463388
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB025409.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB025409.1, DV063560.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 39.11 cM"
     gene            1..757
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /note="CDC28 protein kinase 1b"
                     /db_xref="GeneID:54124"
                     /db_xref="MGI:MGI:1889208"
     exon            1..137
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..318
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /note="cyclin-dependent kinase regulatory subunit 1;
                     CKS-1; sid 1334"
                     /codon_start=1
                     /product="cyclin-dependent kinases regulatory subunit 1"
                     /protein_id="NP_058600.1"
                     /db_xref="CCDS:CCDS38493.1"
                     /db_xref="GeneID:54124"
                     /db_xref="MGI:MGI:1889208"
                     /translation="MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWR
                     NLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPKK"
     exon            138..265
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /inference="alignment:Splign:2.1.0"
     exon            266..757
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /inference="alignment:Splign:2.1.0"
     regulatory      731..736
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /note="hexamer: ATTAAA"
     polyA_site      757
                     /gene="Cks1b"
                     /gene_synonym="2410005G18Rik; 2610005D03Rik; Cks1;
                     sid1334"
                     /note="major polyA site"
ORIGIN      
        1 agagggtggg agcgcgtgct gctgggagtt gtctggaggc ctgcggcgcg gggctgagcg
       61 ccctcggaca gagcaatcat gtcccacaaa caaatctact attcggacaa atacgacgac
      121 gaggagttcg aataccggca tgtcatgttg cccaaggaca tagccaagct ggtcccgaaa
      181 acccatctga tgtctgaatc tgaatggagg aacctcggcg ttcagcagag tcagggatgg
      241 gtccactata tgatccatga accagaacct cacatcttac tgttccgacg gccactgccc
      301 aagaagccaa agaaatgaag ccggcgaacc gccttccggc ctcgagcggt ccacagctgt
      361 cctcactccc tgccatcttt ctgatcgcgt gaccatgttg ctttcttatt tctcactttg
      421 atatgtaaag gatacactgt ttgaatgtgc tggtacctgc tttgcttctg gagttgagcc
      481 accagtgcca cagccctgtc agatgagtgt gacctcaaag ccctcgtgtg cgcgggaccc
      541 agcaggccat attagtcatt tggcagaagc atgtgaaatc tagatcatgg ctgttacaag
      601 gatggtgtga atttgctgac gtgtttttta ctattgggta ttgtatttat gatgacttat
      661 ggatttatgt ttcaatgtat tggaaatttt gcattttatc tgacagatct cttccatgtt
      721 acaagccttg attaaaggaa gttttttata atcttaa
//
