LOCUS       NM_007710               1415 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus creatine kinase, muscle (Ckm), mRNA.
ACCESSION   NM_007710
VERSION     NM_007710.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Cai,S., Wang,X., Xu,R., Liang,Z., Zhu,Q., Chen,M., Lin,Z., Li,C.,
            Duo,T., Tong,X., Li,E., He,Z., Liu,X., Chen,Y. and Mo,D.
  TITLE     KLF4 regulates skeletal muscle development and regeneration by
            directly targeting P57 and Myomixer
  JOURNAL   Cell Death Dis 14 (9), 612 (2023)
   PUBMED   37723138
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  AUTHORS   Dos Santos,M., Shah,A.M., Zhang,Y., Bezprozvannaya,S., Chen,K.,
            Xu,L., Lin,W., McAnally,J.R., Bassel-Duby,R., Liu,N. and Olson,E.N.
  TITLE     Opposing gene regulatory programs governing myofiber development
            and maturation revealed at single nucleus resolution
  JOURNAL   Nat Commun 14 (1), 4333 (2023)
   PUBMED   37468485
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1415)
  AUTHORS   Deuper,L., Meuser,M., Thiesler,H., Jany,U.W.H., Rudat,C.,
            Hildebrandt,H., Trowe,M.O. and Kispert,A.
  TITLE     Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric
            mesenchyme by balancing SHH and BMP4 signaling
  JOURNAL   Development 149 (17) (2022)
   PUBMED   36094016
REFERENCE   4  (bases 1 to 1415)
  AUTHORS   Kurz,J., Weiss,A.C., Thiesler,H., Qasrawi,F., Deuper,L., Kaur,J.,
            Rudat,C., Ludtke,T.H., Wojahn,I., Hildebrandt,H., Trowe,M.O. and
            Kispert,A.
  TITLE     Notch signaling is a novel regulator of visceral smooth muscle cell
            differentiation in the murine ureter
  JOURNAL   Development 149 (4) (2022)
   PUBMED   35103284
REFERENCE   5  (bases 1 to 1415)
  AUTHORS   Zhu,Q., Liang,F., Cai,S., Luo,X., Duo,T., Liang,Z., He,Z., Chen,Y.
            and Mo,D.
  TITLE     KDM4A regulates myogenesis by demethylating H3K9me3 of myogenic
            regulatory factors
  JOURNAL   Cell Death Dis 12 (6), 514 (2021)
   PUBMED   34011940
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1415)
  AUTHORS   Fowlis,G.A., Fairchild,S., Tomonari,K. and Simpson,E.
  TITLE     Toward identification of minor histocompatibility antigens in mouse
            and man
  JOURNAL   Transplant Proc 24 (5), 1689-1691 (1992)
   PUBMED   1412798
REFERENCE   7  (bases 1 to 1415)
  AUTHORS   van Deursen,J. and Wieringa,B.
  TITLE     Targeting of the creatine kinase M gene in embryonic stem cells
            using isogenic and nonisogenic vectors
  JOURNAL   Nucleic Acids Res 20 (15), 3815-3820 (1992)
   PUBMED   1508665
REFERENCE   8  (bases 1 to 1415)
  AUTHORS   Miner,J.H., Miller,J.B. and Wold,B.J.
  TITLE     Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic
            mouse heart
  JOURNAL   Development 114 (4), 853-860 (1992)
   PUBMED   1618148
REFERENCE   9  (bases 1 to 1415)
  AUTHORS   Rudert,F., Saunders,A.M., Rebstock,S., Thompson,J.A. and
            Zimmermann,W.
  TITLE     Characterization of murine carcinoembryonic antigen gene family
            members
  JOURNAL   Mamm Genome 3 (5), 262-273 (1992)
   PUBMED   1638085
REFERENCE   10 (bases 1 to 1415)
  AUTHORS   Lyons,G.E., Muhlebach,S., Moser,A., Masood,R., Paterson,B.M.,
            Buckingham,M.E. and Perriard,J.C.
  TITLE     Developmental regulation of creatine kinase gene expression by
            myogenic factors in embryonic mouse and chick skeletal muscle
  JOURNAL   Development 113 (3), 1017-1029 (1991)
   PUBMED   1668275
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC118017.15.
            
            On Nov 17, 2006 this sequence version replaced NM_007710.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X03233.1, AK009950.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                AC118017.15        43369-43421         c
            54-265              AC118017.15        40185-40396         c
            266-420             AC118017.15        39464-39618         c
            421-553             AC118017.15        38982-39114         c
            554-725             AC118017.15        37625-37796         c
            726-849             AC118017.15        34953-35076         c
            850-1039            AC118017.15        34219-34408         c
            1040-1415           AC118017.15        32932-33307         c
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.67 cM"
     gene            1..1415
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /note="creatine kinase, muscle"
                     /db_xref="GeneID:12715"
                     /db_xref="MGI:MGI:88413"
     exon            1..53
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     exon            54..265
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..1218
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /EC_number="2.7.3.2"
                     /note="creatine kinase M chain; creatine phosphokinase
                     M-type"
                     /codon_start=1
                     /product="creatine kinase M-type"
                     /protein_id="NP_031736.1"
                     /db_xref="CCDS:CCDS20902.1"
                     /db_xref="GeneID:12715"
                     /db_xref="MGI:MGI:88413"
                     /translation="MPFGNTHNKFKLNYKPQEEYPDLSKHNNHMAKVLTPDLYNKLRD
                     KETPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGYKP
                     TDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVE
                     ALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIW
                     HNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEH
                     LGYVLTCPSNLGTGLRGGVHVKLANLSKHPKFEEILTRLRLQKRGTGGVDTAAVGAVF
                     DISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK"
     exon            266..420
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     exon            421..553
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     exon            554..725
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     exon            726..849
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     exon            850..1039
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1415
                     /gene="Ckm"
                     /gene_synonym="Ckmm; CPK-M; M-CK; MCK"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggtcaccac cacctccaca gcacagacag acactcagga gccagccagc cagggtccca
       61 aaggccgcca ccatgccgtt cggcaacacc cacaacaagt tcaagctgaa ctacaagcct
      121 caggaggagt acccagacct cagcaagcac aacaatcaca tggccaaggt gctgacccct
      181 gacctctaca ataagcttcg cgataaggag acaccatccg gcttcactct ggacgatgtc
      241 atccagactg gggtggacaa cccaggtcac cccttcatca tgacggtggg ctgtgtggcc
      301 ggcgatgagg agtcctacac ggtcttcaag gacctgtttg atcccatcat ccaggaccgc
      361 catggcggct acaaacccac agacaagcat aagaccgacc tcaaccacga gaacctcaag
      421 ggtggagacg acctggaccc caactatgtg ctgagcagcc gcgtgcgcac tggccgcagc
      481 atcaagggtt acactctgcc tccgcactgc tcccgtggag agcgccgtgc agtggagaag
      541 ctgtccgtgg aagctctcaa cagcctgacg ggcgagttca agggcaagta ctaccctctg
      601 aagagcatga cggagcagga acagcagcag ctcattgatg accacttcct gtttgacaag
      661 cccgtgtcac ctctgctgct ggcctcaggc atggcccgag actggcccga tgcccgtggc
      721 atctggcaca acgacaacaa aagcttcctt gtgtgggtga acgaggagga ccacctccgc
      781 gtgatctcca tggagaaggg aggcaatatg aaggaggttt tccgccgctt ctgcgtgggc
      841 ctgcagaaga ttgaggagat cttcaagaag gctggtcacc ccttcatgtg gaacgagcac
      901 ctgggctacg tgctcacctg cccctccaac ctgggcaccg ggctgcgcgg aggcgtgcac
      961 gtgaagctgg cgaacctgag caagcacccc aagtttgagg agattctcac tcgccttcgt
     1021 ctgcagaagc gcggcacagg tggcgtggac acggctgcgg tgggcgccgt gttcgacatc
     1081 tccaacgccg atcggctggg ctcatccgaa gtcgaacagg tgcagctggt ggtggatggc
     1141 gtgaagctta tggtggagat ggagaagaag ctggaaaagg gccagtccat cgacgacatg
     1201 atccccgcgc agaagtaggc gcagggcgtg gcgcaccagc ctgcagtgtg cgctggtgcc
     1261 ccgcctcctg gaagtccaat cattgggctc tgtcctctgg gttctggcca atgagaacct
     1321 gcctctccgg agccccgccc acctgcttct caggcgctcc ggagcgccgg ctgcttctcc
     1381 atgccctgcc ttaaataaaa gtccgtgatg gcctt
//
