LOCUS       NM_010828               1980 bp    mRNA    linear   ROD 28-AUG-2024
DEFINITION  Mus musculus Cbp/p300-interacting transactivator, with Glu/Asp-rich
            carboxy-terminal domain, 2 (Cited2), transcript variant 1, mRNA.
ACCESSION   NM_010828
VERSION     NM_010828.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Kuna,M. and Soares,M.J.
  TITLE     Cited2 is a key regulator of placental development and plasticity
  JOURNAL   Bioessays 46 (8), e2300118 (2024)
   PUBMED   38922923
  REMARK    GeneRIF: Cited2 is a key regulator of placental development and
            plasticity.
            Review article
REFERENCE   2  (bases 1 to 1980)
  AUTHORS   Li,Q., Zhang,J., Gao,Z., Zhang,Y. and Gu,J.
  TITLE     Gut microbiota-induced microRNA-206-3p increases anxiety-like
            behaviors by inhibiting expression of Cited2 and STK39
  JOURNAL   Microb Pathog 176, 106008 (2023)
   PUBMED   36736544
  REMARK    GeneRIF: Gut microbiota-induced microRNA-206-3p increases
            anxiety-like behaviors by inhibiting expression of Cited2 and
            STK39.
REFERENCE   3  (bases 1 to 1980)
  AUTHORS   Kuna,M., Dhakal,P., Iqbal,K., Dominguez,E.M., Kent,L.N., Muto,M.,
            Moreno-Irusta,A., Kozai,K., Varberg,K.M., Okae,H., Arima,T.,
            Sucov,H.M. and Soares,M.J.
  TITLE     CITED2 is a conserved regulator of the uterine-placental interface
  JOURNAL   Proc Natl Acad Sci U S A 120 (3), e2213622120 (2023)
   PUBMED   36626551
REFERENCE   4  (bases 1 to 1980)
  AUTHORS   Chen,Z., Chen,H.X., Hou,H.T., Yin,X.Y., Yang,Q. and He,G.W.
  TITLE     Pathophysiological Role of Variants of the Promoter Region of
            CITED2 Gene in Sporadic Tetralogy of Fallot Patients with Cellular
            Function Verification
  JOURNAL   Biomolecules 12 (11), 1644 (2022)
   PUBMED   36358994
  REMARK    GeneRIF: Pathophysiological Role of Variants of the Promoter Region
            of CITED2 Gene in Sporadic Tetralogy of Fallot Patients with
            Cellular Function Verification.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1980)
  AUTHORS   Wagner,N.R., Sinha,A., Siththanandan,V., Kowalchuk,A.M.,
            MacDonald,J.L. and Tharin,S.
  TITLE     miR-409-3p represses Cited2 to refine neocortical layer V
            projection neuron identity
  JOURNAL   Front Neurosci 16, 931333 (2022)
   PUBMED   36248641
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1980)
  AUTHORS   Glenn,D.J. and Maurer,R.A.
  TITLE     MRG1 binds to the LIM domain of Lhx2 and may function as a
            coactivator to stimulate glycoprotein hormone alpha-subunit gene
            expression
  JOURNAL   J Biol Chem 274 (51), 36159-36167 (1999)
   PUBMED   10593900
REFERENCE   7  (bases 1 to 1980)
  AUTHORS   Bhattacharya,S., Michels,C.L., Leung,M.K., Arany,Z.P., Kung,A.L.
            and Livingston,D.M.
  TITLE     Functional role of p35srj, a novel p300/CBP binding protein, during
            transactivation by HIF-1
  JOURNAL   Genes Dev 13 (1), 64-75 (1999)
   PUBMED   9887100
REFERENCE   8  (bases 1 to 1980)
  AUTHORS   Sun,H.B., Zhu,Y.X., Yin,T., Sledge,G. and Yang,Y.C.
  TITLE     MRG1, the product of a melanocyte-specific gene related gene, is a
            cytokine-inducible transcription factor with transformation
            activity
  JOURNAL   Proc Natl Acad Sci U S A 95 (23), 13555-13560 (1998)
   PUBMED   9811838
REFERENCE   9  (bases 1 to 1980)
  AUTHORS   Dunwoodie,S.L., Rodriguez,T.A. and Beddington,R.S.
  TITLE     Msg1 and Mrg1, founding members of a gene family, show distinct
            patterns of gene expression during mouse embryogenesis
  JOURNAL   Mech Dev 72 (1-2), 27-40 (1998)
   PUBMED   9533950
REFERENCE   10 (bases 1 to 1980)
  AUTHORS   Shioda,T., Fenner,M.H. and Isselbacher,K.J.
  TITLE     MSG1 and its related protein MRG1 share a transcription activating
            domain
  JOURNAL   Gene 204 (1-2), 235-241 (1997)
   PUBMED   9434189
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133791.1 and BX516616.1.
            
            On Jun 18, 2009 this sequence version replaced NM_010828.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY705738.1, AK133791.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1941              AK133791.1         2-1942
            1942-1980           BX516616.1         505-543
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 7.18 cM"
     gene            1..1980
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /note="Cbp/p300-interacting transactivator, with
                     Glu/Asp-rich carboxy-terminal domain, 2"
                     /db_xref="GeneID:17684"
                     /db_xref="MGI:MGI:1306784"
     exon            1..232
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /inference="alignment:Splign:2.1.0"
     exon            233..1969
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..1050
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /note="MSG-related protein 1; melanocyte specific gene 2"
                     /codon_start=1
                     /product="cbp/p300-interacting transactivator 2"
                     /protein_id="NP_034958.2"
                     /db_xref="CCDS:CCDS23708.1"
                     /db_xref="GeneID:17684"
                     /db_xref="MGI:MGI:1306784"
                     /translation="MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQP
                     QHAFNALMGEHIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPP
                     VASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPTAGHQMNGTNQHFRDCNPKH
                     SGGSSTPGGAGGSGTPGGSGGTSGGAGGSSAGGSGGGSTMPASVAHVPAAMLPPNVID
                     TDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC"
     regulatory      1931..1936
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /note="hexamer: AATAAA"
     regulatory      1946..1951
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /note="hexamer: AATAAA"
     polyA_site      1951
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
                     /note="major polyA site"
     polyA_site      1969
                     /gene="Cited2"
                     /gene_synonym="ER154-like; Mrg1; Msg2; p35srj"
ORIGIN      
        1 agctcattgt tggcagctgc ctggcggtct tgcggagcgg ctagggcagc ggaggaaaag
       61 aaaagggaac ggctcggaat ttgctccagc ggctgctgca agacctcggc gccaacctcg
      121 caccggcgag cgcctcacag cccatcggct gtccctctat gtgctgctga gccggtcctg
      181 gactcgacga gcccgccttc ggtgttccga gcagaaatcg caaagacgga aggactggaa
      241 atggcagacc atatgatggc catgaaccac gggcgcttcc ccgacggcac caacgggctg
      301 caccaccacc ctgcccaccg catgggcatg gggcagttcc cgagcccgca tcatcaccag
      361 cagcagcagc cccagcacgc cttcaacgcc ctcatgggcg agcacataca ctacggcgcg
      421 ggcaacatga atgccacgag cggcatcagg cacgccatgg ggccggggac tgtgaacggg
      481 gggcaccccc cgagcgctct ggccccggcc gccaggttta acaactccca gttcatgggt
      541 cccccggtgg ccagccaggg aggctccctg ccggccagca tgcagctgca gaagctcaac
      601 aaccagtatt tcaaccatca cccctacccc cacaaccact acatgccgga tttgcacccc
      661 actgcaggcc accagatgaa cgggacaaac cagcacttcc gagattgcaa ccccaagcac
      721 agcggaggca gcagcacccc tggcggtgcg ggtggcagcg gcacccccgg cggctccggc
      781 ggcacctcgg gcggcgcggg tggcagcagc gcgggcggca gcggcggtgg cagcaccatg
      841 cccgcctcgg tggctcacgt ccccgcggca atgctgccgc ccaatgtcat agacactgat
      901 ttcatcgacg aggaagtgct tatgtcctta gtgatagaaa tgggtttgga ccgcatcaag
      961 gagctgcccg aactctggct gggccaaaat gagtttgatt ttatgacgga cttcgtgtgc
     1021 aagcagcagc ccagcagagt cagctgttga ctcggttaac ctcgcaggcg gaaagaaatc
     1081 accctcccca ccccaccccc acccccaact tcttcggtgt gaattaaaaa aaaaacaaaa
     1141 aaacaaacat tcccttagac gcagtatctc gcttttcaga tcctgaaagg gttgagaacc
     1201 tggaaacaaa gtaaactata aacttgtaca aattggttta aaaaaaaaaa agattgctgc
     1261 cactttttcc tattcttgtt tcgttttttg tagccttgac attcacctcc cttatgtagt
     1321 tgaaatatct agctaacttg gtcttttttg ttgtttgttt ttactccttt atttcctcac
     1381 tttctcccgt gctcaactgt tagatattaa gcttggcaaa ctgcttaatc ttgtggattt
     1441 tgtagatggt ttcaaatgac tgcgctgcgt tcagattcat gagtgaaagg aaacattgca
     1501 tttgttggct gcatgatctt tgaagggcag atattactgc acaaactgcc atctcgcttc
     1561 atttttttta actatgcatt cgagtacaga cttaagtttt caaatatgct aaactggaag
     1621 attaaacatg tgggccaaac cgttctggat caggaaaagt cataccgttc actttcaagt
     1681 tggctgtctc ccctccccca tatgtacaga caataatagg gtgtggaatg tcgtcagtgg
     1741 caaacatttc acagattttt attttgtttc tgtcttcaac atttttgaca ctgtgctaat
     1801 agttatattc agtacatgaa aagatactac tgtgttgaaa gctttttagg aaattttgac
     1861 agtatttttg tacaaaacat ttttttgaga aaatacttgt taatttattc tattttaatt
     1921 tgccaatgtc aataaaaagt taagaaataa acttgttttc taaaagtcaa aaaaaaaaaa
//
