LOCUS       NM_134007                965 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Mus musculus CDGSH iron sulfur domain 1 (Cisd1), mRNA.
ACCESSION   NM_134007
VERSION     NM_134007.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 965)
  AUTHORS   Joffin,N., Gliniak,C.M., Funcke,J.B., Paschoal,V.A., Crewe,C.,
            Chen,S., Gordillo,R., Kusminski,C.M., Oh,D.Y., Geldenhuys,W.J. and
            Scherer,P.E.
  TITLE     Adipose tissue macrophages exert systemic metabolic control by
            manipulating local iron concentrations
  JOURNAL   Nat Metab 4 (11), 1474-1494 (2022)
   PUBMED   36329217
REFERENCE   3  (bases 1 to 965)
  AUTHORS   Zhu,Q., Zhu,Y., Hepler,C., Zhang,Q., Park,J., Gliniak,C.,
            Henry,G.H., Crewe,C., Bu,D., Zhang,Z., Zhao,S., Morley,T., Li,N.,
            Kim,D.S., Strand,D., Deng,Y., Robino,J.J., Varlamov,O.,
            Gordillo,R., Kolonin,M.G., Kusminski,C.M., Gupta,R.K. and
            Scherer,P.E.
  TITLE     Adipocyte mesenchymal transition contributes to mammary tumor
            progression
  JOURNAL   Cell Rep 40 (11), 111362 (2022)
   PUBMED   36103820
REFERENCE   4  (bases 1 to 965)
  AUTHORS   Hua,J., Gao,Z., Zhong,S., Wei,B., Zhu,J. and Ying,R.
  TITLE     CISD1 protects against atherosclerosis by suppressing lipid
            accumulation and inflammation via mediating Drp1
  JOURNAL   Biochem Biophys Res Commun 577, 80-88 (2021)
   PUBMED   34509082
  REMARK    GeneRIF: CISD1 protects against atherosclerosis by suppressing
            lipid accumulation and inflammation via mediating Drp1.
REFERENCE   5  (bases 1 to 965)
  AUTHORS   Joffin,N., Paschoal,V.A., Gliniak,C.M., Crewe,C., Elnwasany,A.,
            Szweda,L.I., Zhang,Q., Hepler,C., Kusminski,C.M., Gordillo,R.,
            Oh,D.Y., Gupta,R.K. and Scherer,P.E.
  TITLE     Mitochondrial metabolism is a key regulator of the
            fibro-inflammatory and adipogenic stromal subpopulations in white
            adipose tissue
  JOURNAL   Cell Stem Cell 28 (4), 702-717 (2021)
   PUBMED   33539722
REFERENCE   6  (bases 1 to 965)
  AUTHORS   Wiley,S.E., Paddock,M.L., Abresch,E.C., Gross,L., van der Geer,P.,
            Nechushtai,R., Murphy,A.N., Jennings,P.A. and Dixon,J.E.
  TITLE     The outer mitochondrial membrane protein mitoNEET contains a novel
            redox-active 2Fe-2S cluster
  JOURNAL   J Biol Chem 282 (33), 23745-23749 (2007)
   PUBMED   17584744
REFERENCE   7  (bases 1 to 965)
  AUTHORS   Wiley,S.E., Murphy,A.N., Ross,S.A., van der Geer,P. and Dixon,J.E.
  TITLE     MitoNEET is an iron-containing outer mitochondrial membrane protein
            that regulates oxidative capacity
  JOURNAL   Proc Natl Acad Sci U S A 104 (13), 5318-5323 (2007)
   PUBMED   17376863
  REMARK    GeneRIF: mito- NEET is an important iron-containing protein
            involved in the control of maximal mitochondrial respiratory rates
REFERENCE   8  (bases 1 to 965)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   9  (bases 1 to 965)
  AUTHORS   Colca,J.R., McDonald,W.G., Waldon,D.J., Leone,J.W., Lull,J.M.,
            Bannow,C.A., Lund,E.T. and Mathews,W.R.
  TITLE     Identification of a novel mitochondrial protein ('mitoNEET')
            cross-linked specifically by a thiazolidinedione photoprobe
  JOURNAL   Am J Physiol Endocrinol Metab 286 (2), E252-E260 (2004)
   PUBMED   14570702
  REMARK    GeneRIF: mitoNEET is located in mitochondrial fraction of
            adipocytes.
REFERENCE   10 (bases 1 to 965)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC156270.5 and
            AC153509.3.
            
            On May 1, 2007 this sequence version replaced NM_134007.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK075907.1, AV090880.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               AC156270.5         108818-108943
            127-332             AC156270.5         117248-117453
            333-965             AC153509.3         3029-3661
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 36.88 cM"
     gene            1..965
                     /gene="Cisd1"
                     /gene_synonym="D10Ertd214e; mitoNEET; Zcd1"
                     /note="CDGSH iron sulfur domain 1"
                     /db_xref="GeneID:52637"
                     /db_xref="MGI:MGI:1261855"
     exon            1..126
                     /gene="Cisd1"
                     /gene_synonym="D10Ertd214e; mitoNEET; Zcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            127..332
                     /gene="Cisd1"
                     /gene_synonym="D10Ertd214e; mitoNEET; Zcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            333..965
                     /gene="Cisd1"
                     /gene_synonym="D10Ertd214e; mitoNEET; Zcd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      718..723
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cisd1"
                     /gene_synonym="D10Ertd214e; mitoNEET; Zcd1"
                     /note="hexamer: ATTAAA"
     polyA_site      737
                     /gene="Cisd1"
                     /gene_synonym="D10Ertd214e; mitoNEET; Zcd1"
                     /note="major polyA site"
ORIGIN      
        1 agtgagtggg ccccgaggtc gcgtcttgcc caagtctccg cggtccccag cgctcgctcg
       61 cgcggtcctg ccacggcctt cctgctgccc gcgccatggg cctcagctcc aactccgctg
      121 tgcgagttga gtggatcgcg gccgtcacct ttgctgctgg cacagccgct ctcggttacc
      181 tggcttacaa gaagttctac gctaaagaga atcgcaccaa agctatggtg aatcttcaga
      241 tccagaaaga caacccgaag gtggtgcatg ccttcgacat ggaggatctg ggggataagg
      301 ccgtgtactg ccgatgctgg aggtctaaaa agttcccctt ctgcgatggg gctcacataa
      361 agcacaacga agagactggc gacaacgtag gacctctgat catcaagaaa aaggaaacct
      421 aatggacagt tgcgaggctg cacccagcgt gttgtgatgt cacctgctga tttacgtaga
      481 atggcaccca acccaccgtc tgattggcct ccccggttct agatgtggtt ggtccctgca
      541 aatcacagct ctcatatcca tggcatcggc cttgctactg aaacatgtgg tgcacgtttg
      601 ttgaaagaag aagaaaggct aaaccaacct cgtgctatat gggttatttt ggtcttgtaa
      661 ggatccgttc ctttaaaata atggtcttag aatatagttg tatcttgagg ttaaagtatt
      721 aaattattcc aaaatcatgt acatgtacat tgtacttgtc agtttaaggg agaatctttt
      781 cttatcggtt cgttaacttg gaaagtaacg gggtgtgatg aaattgcgtt gatttcttac
      841 accatgggag aaccctgccg tgaccctcac tcctcctggt tgagctggtg acatggatac
      901 actttgtgtg ctttaatgtt gttctcctta aacttgcccg ggtcaccaat aaaggggcag
      961 caact
//
