LOCUS       NM_026048               2029 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus cyclin dependent kinase 2 interacting protein (Cinp),
            transcript variant 1, mRNA.
ACCESSION   NM_026048
VERSION     NM_026048.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2029)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2029)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2029)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 2029)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101875.7, AK076126.1 and BB761424.1.
            
            On Feb 16, 2011 this sequence version replaced NM_026048.3.
            
            Transcript Variant: This variant (1) represents the predominant
            transcript. It encodes isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160662.1, AK076126.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                AC101875.7         108423-108453       c
            32-2017             AK076126.1         2-1987
            2018-2029           BB761424.1         448-459
FEATURES             Location/Qualifiers
     source          1..2029
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 60.85 cM"
     gene            1..2029
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="cyclin dependent kinase 2 interacting protein"
                     /db_xref="GeneID:67236"
                     /db_xref="MGI:MGI:1914486"
     exon            1..80
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..712
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="cyclin-dependent kinase 2-interacting protein
                     isoform 1"
                     /protein_id="NP_080324.1"
                     /db_xref="CCDS:CCDS36561.1"
                     /db_xref="GeneID:67236"
                     /db_xref="MGI:MGI:1914486"
                     /translation="MEAKTLGIATPRKPVLSVSARKLKDNAADWHNLILKWDSLSDKG
                     FTTASSIANLKVSLLSKEKVELESSSPASMEEEEKTNLDYDKGLEALCEELQAILDGL
                     TKIQMKMEKLSSTTKGICELENYHYREESSRPPLFHTWPTAFFYEVSRRLSEAYKKEL
                     LLKHTIGAELAHTADRNLSLTYLSMWLHQPYIESNSKLQLESMLLETGHRAL"
     exon            81..249
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            250..379
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            380..509
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            510..2029
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      938..943
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="hexamer: TATAAA"
     polyA_site      956
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="major polyA site"
     regulatory      1455..1460
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="hexamer: AATAAA"
     regulatory      1472..1477
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="hexamer: AATATA"
     polyA_site      1477
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="major polyA site"
     polyA_site      1489
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
     regulatory      1996..2001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
                     /note="hexamer: TATAAA"
     polyA_site      2027
                     /gene="Cinp"
                     /gene_synonym="1810047K05Rik; 2810452K22Rik"
ORIGIN      
        1 ggaagtgacg tcacttcctc agttcgcagg cgggtttttg ggtcttctca ggaatctacc
       61 tgtgggccgc cgcatggaag caaagactct tgggatcgca acaccaagaa aacctgtctt
      121 atcagtcagt gcgaggaaac ttaaggacaa tgctgctgac tggcataact taatcctgaa
      181 atgggacagc ctcagtgaca agggcttcac cacagcgagc agtattgcca acctgaaagt
      241 cagcttgctg agtaaagaga aggttgagtt agagagcagc agcccagctt ccatggaaga
      301 ggaagaaaag acaaatctgg actacgataa gggactcgaa gcactgtgtg aggagctgca
      361 ggccatcttg gacggcttga ctaaaataca aatgaaaatg gaaaagctgt cttcaaccac
      421 caagggaatt tgtgagctag aaaattacca ctacagggaa gaaagcagcc ggccccctct
      481 atttcacacg tggcccacag ccttctttta tgaggtctcc cgccggctct ctgaagcata
      541 caagaaggag ctccttttga agcacaccat tggcgcagag ctggcccata ctgcagatcg
      601 caacctcagc ctgacctacc tgtccatgtg gctgcaccag ccctacatag agagcaacag
      661 caagctgcag ctggagagca tgctgctcga gacaggtcac cgggccctgt gactgcctgt
      721 gaccacagct tggagctcca ggccactggc tggacagtca gtcccttggg tggaacctgt
      781 tgtgcctcaa ggccagatac tttgagggtc ctgggatcac tcttcccgct gctgcagcct
      841 ctccagacac aggcactgct gagctgtcct cccgctgctt cccgggtgtc atgaagctcc
      901 actgagtgac agaaacaaga acagctgagg gcagttttat aaatctgtgg agacaacctg
      961 agtttcccat ttctattttg tacctatcta cttttttttt tcttttttgt ggtgctggaa
     1021 atcaaatcaa atcaagactt cacacaagct gaatattcaa ccactggtcc acactgccaa
     1081 ccctgtgctt tgaagagaat gttttagttc tgaaactaac tatcccagga ttattagatg
     1141 ttaaagtctc ataagtaggg acagagtggt gagttagcag ttgagagcac tgtggacttc
     1201 tggcctcccc tggcagcaac acacaaatta cttaggtatc tgtgtatcgg ccgaatgtat
     1261 agatgaccag ggcaactgta aatgggagtg ggctccttgg agttagaact acaagaggtt
     1321 gtcagccacc tgatttgggt gttagaaacc aaactccagt cagtcctctg gaagaacagt
     1381 tcacgctctt aactgctgag ccatctctcc tatggctgga gatacatata tttaatatat
     1441 tgtataaata tattaataaa acatgtattg aaatatatat acatattaat cctgttgagt
     1501 taactgagta tagagtttag tatcacagaa atgaaaatca cccaaaattg ctgctgcttg
     1561 cctgagaaaa tggacaagcc aatacaaaga ccagcagttg cagactgttt gtatctgggg
     1621 cctggccgtg ctagatgttt agctttctca ctgttcgcca ccggtgtact ccctaagtcc
     1681 atagagagct aacattcatc atgaagagtt gcctgcatag tgaggtcagc tggccctcac
     1741 agttaggtca ggggccgctt gcacttcctc ctttcactcc ttcctgatag ggaacacact
     1801 aagaccactg gggtgggcac tcttggacca ctgctcccat ctttagggga aggaatactc
     1861 agaccacatt gctaccttct gtgtatgtgt ctgtataggc acacttgagc tacgttgcat
     1921 gtgtgcaggt cagaggacag ctttgggttg tgggtccttg ccttctgcct tgacataggg
     1981 cctcttgttc actgctataa acaccaggat acctggcctg caagcttcc
//
