LOCUS       NM_001369077            1036 bp    mRNA    linear   ROD 21-SEP-2024
DEFINITION  Mus musculus ciliary microtubule inner protein 2B (Cimip2b),
            transcript variant 3, mRNA.
ACCESSION   NM_001369077
VERSION     NM_001369077.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1036)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1036)
  AUTHORS   Chen,Z., Shiozaki,M., Haas,K.M., Skinner,W.M., Zhao,S., Guo,C.,
            Polacco,B.J., Yu,Z., Krogan,N.J., Lishko,P.V., Kaake,R.M.,
            Vale,R.D. and Agard,D.A.
  TITLE     De novo protein identification in mammalian sperm using in situ
            cryoelectron tomography and AlphaFold2 docking
  JOURNAL   Cell 186 (23), 5041-5053 (2023)
   PUBMED   37865089
REFERENCE   3  (bases 1 to 1036)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732506.10.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.4375339.1,
                                           SRR7652917.1166878.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               AL732506.10        43189-43295         c
            108-331             AL732506.10        42404-42627         c
            332-528             AL732506.10        42134-42330         c
            529-580             AL732506.10        41949-42000         c
            581-778             AL732506.10        41674-41871         c
            779-1036            AL732506.10        41175-41432         c
FEATURES             Location/Qualifiers
     source          1..1036
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 23.03 cM"
     gene            1..1036
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /note="ciliary microtubule inner protein 2B"
                     /db_xref="GeneID:329831"
                     /db_xref="MGI:MGI:2445194"
     exon            1..107
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..867
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /note="isoform 3 is encoded by transcript variant 3;
                     protein FAM166B; family with sequence similarity 166,
                     member B"
                     /codon_start=1
                     /product="ciliary microtubule inner protein 2B isoform 3"
                     /protein_id="NP_001356006.1"
                     /db_xref="CCDS:CCDS89735.1"
                     /db_xref="GeneID:329831"
                     /db_xref="MGI:MGI:2445194"
                     /translation="MAVVNTSIPGLSGENPHYIPGYTGHCPLLRFSMGQTYGQVTGQL
                     LRGPPGLAWPPAHRTLLPPIQSPRSPVISKGRLPPRRGHERLSSSIIPGYTGFIPRAQ
                     FIFAKNCNQVWAEAMSEFTRRHGEQESHQLPDGAKGEREVEEDQLREAEEPPLKQELA
                     HASPYSMDDTDPHKFFMSGFTGYVPRARFLFGSSFPVLTNQALQEFGQMCSRGRAHKD
                     PKPLSPLPRPTFQNLGLLPHYGGYVPGYKFQFGGTFGHLTHDALGLSITQKQLPA"
     exon            108..331
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /inference="alignment:Splign:2.1.0"
     exon            332..528
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /inference="alignment:Splign:2.1.0"
     exon            529..580
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /inference="alignment:Splign:2.1.0"
     exon            581..778
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /inference="alignment:Splign:2.1.0"
     exon            779..1036
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1014..1019
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /note="hexamer: AATAAA"
     polyA_site      1033
                     /gene="Cimip2b"
                     /gene_synonym="4833436C18Rik; Fam166b"
                     /note="major polyA site"
ORIGIN      
        1 agagtccctc ctggaaggga aataaaagga actgcgccag ttcccatggc tgtggtcaac
       61 acttccatcc cagggctcag cggcgagaat ccgcattata ttccagggta caccggacac
      121 tgcccgctac ttcggttcag catgggccag acctatgggc aggtgactgg tcagctactc
      181 cgaggccctc ctggtctagc ctggcctcct gcccaccgca cacttctgcc tcccatccag
      241 tctccaagat ctcctgtgat ctccaagggg aggctgcctc ccaggcgcgg gcatgaaagg
      301 ctcagctcca gcataatccc tgggtataca ggttttatac cacgggcaca gttcattttt
      361 gccaagaact gcaaccaggt ttgggctgaa gctatgagtg aatttacacg aaggcacggg
      421 gagcaagaga gccatcaact gccagacgga gccaagggag agagagaagt ggaagaagac
      481 cagctgcggg aggcagagga gccaccgctg aagcaggagt tggcacatgc ttccccctac
      541 tccatggatg atacagatcc ccacaagttc ttcatgtcag gtttcacggg ctatgtgccc
      601 cgtgcccgct tcctctttgg ctccagcttc cctgtgctta ccaaccaggc attgcaggaa
      661 tttgggcaga tgtgctcacg gggccgggcg cacaaggacc ccaaacctct ctccccactt
      721 cccaggccca cgtttcagaa tctgggtctc ctacctcact acggaggcta cgtgccagga
      781 tataagttcc agtttggcgg tacatttggg catcttaccc atgatgctct gggcctcagc
      841 attactcaga aacagctccc ggcctaagta cctggattcc aagttctccc ttctcatcct
      901 aacccagtga accttttgga atgaagagag gtgggtcggg gaggggcaca aagaaaatgg
      961 cttggaggct gagcaccttt ttattattag gtgtaataaa taaataataa ataaataaat
     1021 acatacataa acagaa
//
