LOCUS       NM_026558               1920 bp    mRNA    linear   ROD 13-AUG-2024
DEFINITION  Mus musculus CBY1 interacting BAR domain containing 1 (Cibar1),
            transcript variant 1, mRNA.
ACCESSION   NM_026558
VERSION     NM_026558.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1920)
  AUTHORS   Wang,L., Yang,Z., Satoshi,F., Prasanna,X., Yan,Z., Vihinen,H.,
            Chen,Y., Zhao,Y., He,X., Bu,Q., Li,H., Zhao,Y., Jiang,L., Qin,F.,
            Dai,Y., Zhang,N., Qin,M., Kuang,W., Zhao,Y., Jokitalo,E.,
            Vattulainen,I., Kajander,T., Zhao,H. and Cen,X.
  TITLE     Membrane remodeling by FAM92A1 during brain development regulates
            neuronal morphology, synaptic function, and cognition
  JOURNAL   Nat Commun 15 (1), 6209 (2024)
   PUBMED   39043703
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1920)
  AUTHORS   Hoque,M., Li,F.Q., Weber,W.D., Chen,J.J., Kim,E.N., Kuo,P.L.,
            Visconti,P.E. and Takemaru,K.I.
  TITLE     The Cby3/ciBAR1 complex positions the annulus along the sperm
            flagellum during spermiogenesis
  JOURNAL   J Cell Biol 223 (3) (2024)
   PUBMED   38197861
  REMARK    GeneRIF: The Cby3/ciBAR1 complex positions the annulus along the
            sperm flagellum during spermiogenesis.
REFERENCE   3  (bases 1 to 1920)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 1920)
  AUTHORS   Olthof,A.M., White,A.K., Mieruszynski,S., Doggett,K., Lee,M.F.,
            Chakroun,A., Abdel Aleem,A.K., Rousseau,J., Magnani,C.,
            Roifman,C.M., Campeau,P.M., Heath,J.K. and Kanadia,R.N.
  TITLE     Disruption of exon-bridging interactions between the minor and
            major spliceosomes results in alternative splicing around minor
            introns
  JOURNAL   Nucleic Acids Res 49 (6), 3524-3545 (2021)
   PUBMED   33660780
REFERENCE   5  (bases 1 to 1920)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1920)
  AUTHORS   Schrauwen,I., Giese,A.P., Aziz,A., Lafont,D.T., Chakchouk,I.,
            Santos-Cortez,R.L.P., Lee,K., Acharya,A., Khan,F.S., Ullah,A.,
            Nickerson,D.A., Bamshad,M.J., Ali,G., Riazuddin,S., Ansar,M.,
            Ahmad,W., Ahmed,Z.M. and Leal,S.M.
  TITLE     FAM92A Underlies Nonsyndromic Postaxial Polydactyly in Humans and
            an Abnormal Limb and Digit Skeletal Phenotype in Mice
  JOURNAL   J Bone Miner Res 34 (2), 375-386 (2019)
   PUBMED   30395363
  REMARK    GeneRIF: a new nonsyndromic autosomal recessive nonsyndromic
            postaxial polydactyly type A ciliopathy due to a loss-of-function
            variant in FAM92A.
REFERENCE   7  (bases 1 to 1920)
  AUTHORS   Breslow,D.K., Hoogendoorn,S., Kopp,A.R., Morgens,D.W., Vu,B.K.,
            Kennedy,M.C., Han,K., Li,A., Hess,G.T., Bassik,M.C., Chen,J.K. and
            Nachury,M.V.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
REFERENCE   8  (bases 1 to 1920)
  AUTHORS   Li,F.Q., Chen,X., Fisher,C., Siller,S.S., Zelikman,K., Kuriyama,R.
            and Takemaru,K.I.
  TITLE     BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To
            Facilitate Ciliogenesis
  JOURNAL   Mol Cell Biol 36 (21), 2668-2680 (2016)
   PUBMED   27528616
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 1920)
  AUTHORS   Huang,L., Song,M., Yang,H.S., Zhang,Y.G. and Hu,H.Z.
  TITLE     [Cloning, expression, distribution and subcellular localization of
            AK078438 gene]
  JOURNAL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24 (3), 271-274 (2007)
   PUBMED   17557235
  REMARK    GeneRIF: Protein expression, expressing profile and subcellular
            localization of AK078438 gene set the basis for further exploration
            of its functions.[AK078438]
REFERENCE   10 (bases 1 to 1920)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ064072.1, AK078438.1, BC055848.1, AL929413.13 and BE953978.1.
            
            On Jul 18, 2015 this sequence version replaced NM_026558.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078438.1, AK088705.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                CJ064072.1         2-21
            21-1311             AK078438.1         2-1292
            1312-1326           BC055848.1         2230-2244
            1327-1583           AL929413.13        54807-55063         c
            1584-1920           BE953978.1         1-337               c
FEATURES             Location/Qualifiers
     source          1..1920
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 5.58 cM"
     gene            1..1920
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /note="CBY1 interacting BAR domain containing 1"
                     /db_xref="GeneID:68099"
                     /db_xref="MGI:MGI:1915349"
     exon            1..318
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..1153
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM92A1; family with sequence similarity 92,
                     member A; CBY1-interacting BAR domain-containing protein
                     1"
                     /codon_start=1
                     /product="CBY1-interacting BAR domain-containing protein 1
                     isoform 1"
                     /protein_id="NP_080834.3"
                     /db_xref="CCDS:CCDS51123.1"
                     /db_xref="GeneID:68099"
                     /db_xref="MGI:MGI:1915349"
                     /translation="MPSGLPCPALDRRGARRVATETPGRRGGAHCALSAPGRSGGVAC
                     SRAPWRPGAALVGLPSWVPGGGKGKMLRRNLDERDAQTKQLQDAVTNVEKHFGELCQI
                     FAAYVRKTARLRDKADLLVNEINLYASTETPNLKQGLKDFADEFAKLQDYRQAEVERL
                     EAKVVEPLKAYGTIVKMKRDDLKATLTARNREAKQLSQLERTRQRNPSDRHVISQAET
                     ELQRATIDATRTSRHLEETIDNFEKQKIKDIKNILSEFITIEMLFHGKALEVFTAAYQ
                     NIQNIDEDEDLEVFRNSLYLSDYPSRLDIVRANSKSPLQRSLSTKCTSGTGQISTCRT
                     RKDQQVEDEDDEELDVTEDEN"
     exon            319..553
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            554..622
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            623..724
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            725..730
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            731..835
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            836..949
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1069
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1906
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1291
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /note="major polyA site"
     regulatory      1300..1305
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /note="hexamer: ATTAAA"
     regulatory      1477..1482
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
                     /note="hexamer: AAGAAA"
     polyA_site      1499
                     /gene="Cibar1"
                     /gene_synonym="6720467C03Rik; Fam92a; Fam92a1"
ORIGIN      
        1 ggttttcctc cttcgctccc agaagcctgg gagggctaga gagctgcagg agctgaagga
       61 ggatgcttgg tgttccctct gccccatgcc ctctggtctc ccttgccctg ctcttgaccg
      121 ccggggcgcg cgccgcgtcg ccacggaaac gccgggcagg cggggcggcg cgcactgcgc
      181 gctctcagct cccggtagaa gtggcggcgt cgcctgctcc cgcgcgccct ggcggcccgg
      241 agccgcgctc gttgggctcc catcctgggt cccgggcggc gggaaaggca agatgttgag
      301 gcgcaatctg gatgagcgag atgctcaaac aaaacaactg caggatgctg tcacaaatgt
      361 ggagaagcat tttggagagc tttgccaaat ctttgctgct tatgtacgga aaactgccag
      421 gcttcgagac aaagccgacc tcctagtgaa cgaaatcaac ctgtatgcct ctaccgagac
      481 accaaattta aagcagggtc tgaaagactt tgctgatgag tttgccaaac ttcaagatta
      541 tcgccaggca gaggttgaaa gacttgaagc caaagtagtt gaacctttga aagcttatgg
      601 gaccattgta aagatgaagc gagatgatct caaagcaaca ttaacagcaa ggaatcgaga
      661 agccaaacag ctatctcagt tagaaaggac acgccagcga aacccatctg atcgacatgt
      721 aatttcgcag gcagaaactg aattacagag agccacgatt gatgctaccc gcacaagtcg
      781 tcatttggag gaaactattg acaattttga aaagcagaaa ataaaggaca taaagaacat
      841 attatctgag ttcatcacaa ttgaaatgtt atttcatgga aaagccttag aggtcttcac
      901 tgctgcctac caaaatatac aaaacattga tgaggatgaa gacctagagg ttttccgaaa
      961 ttctctgtat ctatcagatt atccatctcg cttagatatt gtaagagcaa attcaaagtc
     1021 acctcttcag agatcattgt caactaagtg cacatctgga actggacaga tatccacctg
     1081 ccgaacaagg aaggaccaac aagtagaaga tgaagatgat gaagaattag atgttacaga
     1141 agatgaaaac taatttacac aaagaattca catttctgtt tttatgtcat ctaacttgca
     1201 aatgtagaat cactttaaac tcacttgaca ggttaaactg taaaatgaaa tgctattatg
     1261 aaactggggg cagaggggaa attaaaggaa attatgctga ttaaaaaaaa gatttttttt
     1321 tctggattac atagtctttc tttcatcatc ctacatatgg tagtgtatat ttttctatat
     1381 atgttctatt aaaaaagatt gtatttctaa gcatttcaga tttaatgcac tataaattca
     1441 tgtgtgactc acaaaatcac atacctatta aaggtgaaga aagtatgtga gtaacaaaag
     1501 atttaataat gcctcatact ttcttttagg ataaaatttg aggttttgat taccagaaga
     1561 ggtcagttaa taatcctatg ccctaatgcc ttaagtaaaa acactgcttc ttttactttt
     1621 attatataac cttatgtttc atcatctggt atgaaaattt agtgttttta actaaaattg
     1681 aacacagtaa tgatttgaga tactgataac aggttttata agtgtatata taaatgatta
     1741 cattctaatt ttaaaaggcc acattcaacc tttcgtgttt taaaacaaaa ctgctctcac
     1801 tctacagctc tgcacattct acttgtataa gttattaata attggaaggc aagtactttg
     1861 ctaaaaatgt tgccttatct tagaatgtca taaagcatta aacacaaaaa aaaaaaaaaa
//
