LOCUS       NM_001411320            1792 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus circadian associated repressor of transcription
            (Ciart), transcript variant 3, mRNA.
ACCESSION   NM_001411320
VERSION     NM_001411320.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1792)
  AUTHORS   Ono,D., Honma,K.I., Schmal,C., Takumi,T., Kawamoto,T., Fujimoto,K.,
            Kato,Y. and Honma,S.
  TITLE     CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression
            of coherent circadian rhythm but not in generation of circadian
            oscillation in the neonatal mouse SCN
  JOURNAL   Sci Rep 11 (1), 19240 (2021)
   PUBMED   34584158
  REMARK    GeneRIF: CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in
            expression of coherent circadian rhythm but not in generation of
            circadian oscillation in the neonatal mouse SCN.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1792)
  AUTHORS   Anafi,R.C., Lee,Y., Sato,T.K., Venkataraman,A., Ramanathan,C.,
            Kavakli,I.H., Hughes,M.E., Baggs,J.E., Growe,J., Liu,A.C., Kim,J.
            and Hogenesch,J.B.
  TITLE     Machine learning helps identify CHRONO as a circadian clock
            component
  JOURNAL   PLoS Biol 12 (4), e1001840 (2014)
   PUBMED   24737000
  REMARK    GeneRIF: CHRONO interferes with the ability of BMAL1 to recruit
            CBP, a bona fide histone acetylase and key transcriptional
            coactivator of the circadian clock.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1792)
  AUTHORS   Goriki,A., Hatanaka,F., Myung,J., Kim,J.K., Yoritaka,T., Tanoue,S.,
            Abe,T., Kiyonari,H., Fujimoto,K., Kato,Y., Todo,T., Matsubara,A.,
            Forger,D. and Takumi,T.
  TITLE     A novel protein, CHRONO, functions as a core component of the
            mammalian circadian clock
  JOURNAL   PLoS Biol 12 (4), e1001839 (2014)
   PUBMED   24736997
  REMARK    GeneRIF: Chrono binds to the regulatory region of clock genes and
            its occupancy oscillates in a circadian manner.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1792)
  AUTHORS   Annayev,Y., Adar,S., Chiou,Y.Y., Lieb,J.D., Sancar,A. and Ye,R.
  TITLE     Gene model 129 (Gm129) encodes a novel transcriptional repressor
            that modulates circadian gene expression
  JOURNAL   J Biol Chem 289 (8), 5013-5024 (2014)
   PUBMED   24385426
  REMARK    GeneRIF: The GM129 protein contributes to the transcriptional
            feedback loop by modulating CLOCK.BMAL1 activity as a
            transcriptional repressor.
REFERENCE   5  (bases 1 to 1792)
  AUTHORS   Nishiguchi,S., Sakuma,R., Nomura,M., Zou,Z., Jearanaisilavong,J.,
            Joh,T., Yasunaga,T. and Shimada,K.
  TITLE     A catalogue of genes in mouse embryonal carcinoma F9 cells
            identified with expressed sequence tags
  JOURNAL   J Biochem 119 (4), 749-767 (1996)
   PUBMED   8743579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092855.39.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784649.785622.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-368               AC092855.39        59256-59623         c
            369-466             AC092855.39        58878-58975         c
            467-875             AC092855.39        58104-58512         c
            876-951             AC092855.39        57906-57981         c
            952-1030            AC092855.39        57558-57636         c
            1031-1142           AC092855.39        57332-57443         c
            1143-1792           AC092855.39        55423-56072         c
FEATURES             Location/Qualifiers
     source          1..1792
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.42 cM"
     gene            1..1792
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /note="circadian associated repressor of transcription"
                     /db_xref="GeneID:229599"
                     /db_xref="MGI:MGI:2684975"
     exon            1..368
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     exon            369..466
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     exon            467..875
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     exon            876..951
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1030
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1142
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1792
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1770..1775
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /note="hexamer: ATTAAA"
     polyA_site      1792
                     /gene="Ciart"
                     /gene_synonym="Chrono; Gm129"
                     /note="major polyA site"
ORIGIN      
        1 acacacgttg cggacacgag ttgctgaggg ctcccacgtg ctgcgcccgt gcgcggaggc
       61 gctcagaggg gcccacgtcc cgaggcgcca cctccgtggc tcggccccgc tctgtacact
      121 ccagccgtgc gtctcccgcg cagtgctgtc ctatttaagg ctatgagctc cacccttttc
      181 cgccccttcc ttaattttca cttttttcca tcctcctttt ttatcacccg aggagccgca
      241 tgtacgggcg gagcatggac tgcttccctt ccagccaatc accacttggc tgcctctcta
      301 ttggccgagc ccccgcgtgc cgtagcaaat gggctgtgag cgtctgcatc tagagtcacg
      361 tgttgccggc gcgaccgtag actgaccagc gcagtgcacc tgatggtgaa ggatgcgaaa
      421 gcggtggagc cgggtgtcta tggggccgga actctaggga cctgagttgc aggttctgat
      481 ctttggtact acgggagctg ctcttcagcc cctctcctgc tcctggacct atggattctc
      541 catctagtgt ttcttcttat tcctcctcct ccctctcccc atcattttcc acgtcctctg
      601 tgaacagtga ctttagcttc ccttctgata acgagaggga gggcaagggc acccatgagc
      661 tcaggccaga cactgtgggt cagagaggag gttccaggcc cagtccaggc cctatccgct
      721 gcagacatcg acccagggtt tctagtaacc aacatacagc acctcatctg gaacagcaag
      781 gatctgaagt caagagatca agagacggtg aacaggagac gagtctgaac acccaaggat
      841 gtactacaga gggagatctg ctctttgctc aaaagtgtaa agaactccaa gggttcatac
      901 ggcccctcac agacctactg aacggactca agatgggtcg ctttgacaga ggattaagta
      961 gcttccaaca gagtgtggcc atggaccgga tccagcgcat agtgggtgtt ttacagaagc
     1021 ctcagatggg agaacgttat ctaggaacct tgctgcaggt ggaagggatg ttaaagactt
     1081 ggtttcctca catagctgcc cagaagtcat cctcaggagg tagccggcac cagataagca
     1141 agcactttcc cagccaccac ggtgaccccg gggctgcttc tcctgcacct ctcctagaga
     1201 agatgggcca aacacagctg ggacatttag ttttgaaacc aaagcagcct tggcatctca
     1261 ctggatggcc agctatgaac ctcacctgga ttcatagcac tccaatttgt aaccctcccc
     1321 tcagctccca aggctccgcc tctggccaca gccccatagg cactggagcc agcattggtg
     1381 tcatccttgt cctccagaaa ggaggacagc ccttcaccca ttctgccccg ggcactccgg
     1441 tcccaccaac tccactgtct cctgtcgtcc ctggtgatct gaagaaactg cctggcgagg
     1501 agcctcgttg ccacagtttg ccagtaacac tgccatcaga ctggagttgc atcctatgtc
     1561 cgcctgtcct gcctaccaca gacagagaga tgactaaagg acacccagag ccacagatga
     1621 ctagccatcc cccagttgct ccggatcctc agccctaacc caggctctgc ttctttcccc
     1681 tgattcccaa tttgtataaa tgtatgtttt atgtgtattt ttttttttac tttaatgtat
     1741 ttgtggtgag gaaatagaaa tcctttctga ttaaagacat tttttactta aa
//
