LOCUS       NM_025296               3075 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus cytosolic iron-sulfur protein assembly 1 (Ciao1),
            mRNA.
ACCESSION   NM_025296
VERSION     NM_025296.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 3075)
  AUTHORS   Fu,H., Cai,J., Clevers,H., Fast,E., Gray,S., Greenberg,R.,
            Jain,M.K., Ma,Q., Qiu,M., Rowitch,D.H., Taylor,C.M. and Stiles,C.D.
  TITLE     A genome-wide screen for spatially restricted expression patterns
            identifies transcription factors that regulate glial development
  JOURNAL   J Neurosci 29 (36), 11399-11408 (2009)
   PUBMED   19741146
REFERENCE   4  (bases 1 to 3075)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 3075)
  AUTHORS   Thomas,J.W. and Green,E.D.
  CONSRTM   NISC Comparative Sequencing Program
  TITLE     Comparative sequence analysis of a single-gene conserved segment in
            mouse and human
  JOURNAL   Mamm Genome 14 (10), 673-678 (2003)
   PUBMED   14694903
REFERENCE   6  (bases 1 to 3075)
  AUTHORS   Johnstone,R.W., Tommerup,N., Hansen,C., Vissing,H. and Shi,Y.
  TITLE     Structural organization, tissue expression, and chromosomal
            localization of Ciao 1, a functional modulator of the Wilms' tumor
            suppressor, WT1
  JOURNAL   Immunogenetics 49 (10), 900-905 (1999)
   PUBMED   10438340
REFERENCE   7  (bases 1 to 3075)
  AUTHORS   Johnstone,R.W., Wang,J., Tommerup,N., Vissing,H., Roberts,T. and
            Shi,Y.
  TITLE     Ciao 1 is a novel WD40 protein that interacts with the tumor
            suppressor protein WT1
  JOURNAL   J Biol Chem 273 (18), 10880-10887 (1998)
   PUBMED   9556563
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BI734652.1, AK028376.1 and BU555826.1.
            
            On Nov 18, 2008 this sequence version replaced NM_025296.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028376.1, SRR1660815.213410.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-712               BI734652.1         1-712
            713-1421            AK028376.1         640-1348
            1422-1422           BU555826.1         231-231
            1423-3075           AK028376.1         1349-3001
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 61.86 cM"
     gene            1..3075
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="cytosolic iron-sulfur protein assembly 1"
                     /db_xref="GeneID:26371"
                     /db_xref="MGI:MGI:1346998"
     exon            1..335
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1216
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="WD repeat domain 39; WD repeat-containing protein
                     39; WD40 protein Ciao1; cytosolic iron-sulfur protein
                     assembly 1 homolog"
                     /codon_start=1
                     /product="probable cytosolic iron-sulfur protein assembly
                     protein CIAO1"
                     /protein_id="NP_079572.2"
                     /db_xref="CCDS:CCDS16696.1"
                     /db_xref="GeneID:26371"
                     /db_xref="MGI:MGI:1346998"
                     /translation="MKDSLVLQSRVPAHPDSRCWFLAWNPSGTLLASCGGDRKIRIWG
                     TEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLE
                     GHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLSSHTQDVKHVVWHP
                     SQELLASASYDDTVKLYQEEGDDWVCCATLEGHESTVWSIAFDPSGQRLASCSDDRTV
                     RIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHTRTIYDVAWCQLTGALATACGDDAI
                     RVFEEDPGSDPQQPTFSLTAHLRQAHSQDVNCVAWNPKEPGLLASCSDDGEVAFWEYH
                     QPAGL"
     exon            336..484
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     exon            485..596
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     exon            597..685
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     exon            686..887
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     exon            888..975
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     exon            976..3075
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1383..1388
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="hexamer: ATTAAA"
     polyA_site      1403
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="major polyA site"
     regulatory      1446..1451
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="hexamer: AATATA"
     regulatory      1456..1461
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="hexamer: AATAAG"
     polyA_site      1457
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="major polyA site"
     polyA_site      1472
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
     regulatory      1489..1494
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="hexamer: AATAAT"
     polyA_site      1508
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
     regulatory      2666..2671
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="hexamer: AATACA"
     polyA_site      2688
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
     regulatory      2984..2989
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
                     /note="hexamer: AATGAA"
     polyA_site      3011
                     /gene="Ciao1"
                     /gene_synonym="Wdr39"
ORIGIN      
        1 gcttccagtt acggaggatg aggggagtga ctacaagtcc cagaaggtca cgcggcgtca
       61 acagcgggca cgtcaattcc tagggcgaca tattttgcag aagctgtaca tctgacggtc
      121 tcaaggttct atagtgccca gcgcgtttgg cgcgttgctt ctctcggtgt gctctcctta
      181 ccctaaaaca gtcgccatga aagattctct ggtactgcag agccgcgtcc cggcgcaccc
      241 ggattcccgc tgctggttcc tggcctggaa cccctcgggg accctgttgg cttcctgcgg
      301 aggcgaccgt aaaattcgca tctggggcac cgagggtgac agctggattt gcaagtctgt
      361 cctttctgaa ggccatcagc gcaccgttag gaaagtggcc tggtccccgt gtggaaatta
      421 cctggcatct gccagctttg atgccaccac ttgtatttgg aagaagaacc aggatgactt
      481 tgagtgtgtg accactcttg agggccatga aaatgaggtc aagtcagtgg cttgggcccc
      541 atctggcaac ctcttggcta cctgcagcag agataagagc gtgtgggtct gggaagttga
      601 tgaagaggat gagtatgagt gtgtcagtgt cctcagctct catacgcagg acgttaagca
      661 cgtggtttgg cacccgagcc aggagctttt agcttctgct agctatgatg acacagtgaa
      721 gctataccag gaagaagggg atgactgggt ctgctgtgcc accctcgaag gtcatgagtc
      781 cactgtttgg agcatagcct ttgatcccag cggccagcgg ctggcatctt gcagtgatga
      841 ccgaactgta cgcatctggc gccagtatct accgggcaat gaacaagggg tggcatgcag
      901 tggctctgac cccagctgga aatgtatctg cactttgtcg ggcttccaca ccaggaccat
      961 ttacgacgtt gcttggtgtc agctgacagg ggccttggct acagcttgtg gagatgatgc
     1021 catccgagtg tttgaggaag acccaggctc agacccacag cagcccacct tctctctgac
     1081 agcccatctt cgtcaggccc attcccagga tgtcaactgt gtggcttgga atcccaagga
     1141 gccagggctc ctggcctctt gtagtgatga tggggaggta gccttctggg agtatcacca
     1201 gcctgcaggt ctctgagcta tagcttgact tgggagtctt gattcccaca gaaaacgtcc
     1261 taagacttct agtcgtcaag aagacctgaa gcatccttga ccttcatttt gctcaggact
     1321 attcactgtt tcccttcctt gaggaagcca ttggagagag ccacagaaca gcagtatatt
     1381 gtattaaagt tttgcttgat ttagggcatg gtgttacatt ttgggggtaa aatatattta
     1441 taatcaatat atatgaataa gagcttttga aattgtgatc tttatagaaa taatccatct
     1501 gtgctccact tcctgtttta taagtaaggt catttatcat ttcttataac ttgactattg
     1561 ggaataagct ccactgtccc aattctagag tagttcttgc atttaaaaca tgcaagctag
     1621 ctgtagtgtt ttcctagcac tcaatcggca aagacgggct atactttgct gcatagtaag
     1681 tttgaagcca gcctgggatg agaccctttt ctcaaaaaac aaagacattc aaaactagag
     1741 gaatttcccc ccaaaaatgt aagtttgttc atagtaaaag gacacctctg cttttcctta
     1801 gaaaccctca tatgcctctt gagacattat gctgtgggct tctgaggata tgaaaagaaa
     1861 tgaactccta taaagaggag gttttcagtg agggacacaa aacatctaca aagtgagttc
     1921 caagacagct aaggagacag tgaccataga aaaaccaaaa atcaaatctt tggtgttttt
     1981 cagggccaag aatagttaag gtgtctaatt agccttttag aagaatgcga ttagacagtg
     2041 agaaatgctt acaggtttgg gtgtgagttg tctccaaaac tggagccttc acttaacttt
     2101 ttacactgta caactgtgac cttagatttt tgcagacagt ggagacatag cgttgactag
     2161 tggtctgtag attcctggga aggtcaacac tgtatcatga tcaaggaatg gcaccagtta
     2221 agtctctatc tgtcttcttt atcttcttca tagtgagaat ggagccagct tcactcaaga
     2281 caacaaacat gacttaaaat tgacattgag accatttctg atactgacaa atgagaaagt
     2341 tccacctagc ccctctgaaa tgaagatagt cttgaggaaa aacagttgga cagttgctac
     2401 tagccaagtt agctattcat ggcatgtatt tttaaagtca gaactagaag attagcattt
     2461 aggcttgtat atttagctgt gttcctgaaa aatgaacata ctgaaccttt cactgatagt
     2521 gttcactgct gatggtaaat gtttaaaaga caaaattaga atttctgaaa acttgtgttt
     2581 caacaaactt taatggtatt gaaactagca aatgcatgga tattttgagg tctgtggaat
     2641 tttgtgggtc actgttgaaa tgaccaatac actggcatta caaaatcatt ttgtgactct
     2701 aagatggggc agtggtttta acagtacagg atgcatgggt acagctgagg agcctacact
     2761 gcctttagga aacttccaca tacagtacca tacagtagta tctaaggaca gccacagtga
     2821 tttggaaact cttctttccc aacctgaagt tgacatgctc agctcaacca tacaacagac
     2881 tgagcagaca cgctaactgg cttctcttaa gctagacgta aagtgattat aacactgtac
     2941 catgctactc ttctcccagg atttattttt cttaaaatat gttaatgaag tttttttttt
     3001 taaaaaacaa actgccttaa tttttaatgt aacaagtatc aatgaatata acctaggtaa
     3061 taaaagcttt ggggg
//
