LOCUS       NM_139134               2535 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus chondrolectin (Chodl), transcript variant 1, mRNA.
ACCESSION   NM_139134
VERSION     NM_139134.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2535)
  AUTHORS   Munguba,H., Nikouei,K., Hochgerner,H., Oberst,P., Kouznetsova,A.,
            Ryge,J., Munoz-Manchado,A.B., Close,J., Batista-Brito,R.,
            Linnarsson,S. and Hjerling-Leffler,J.
  TITLE     Transcriptional maintenance of cortical somatostatin interneuron
            subtype identity during migration
  JOURNAL   Neuron 111 (22), 3590-3603 (2023)
   PUBMED   37625400
REFERENCE   3  (bases 1 to 2535)
  AUTHORS   Farmer,D.T., Mlcochova,H., Zhou,Y., Koelling,N., Wang,G.,
            Ashley,N., Bugacov,H., Chen,H.J., Parvez,R., Tseng,K.C.,
            Merrill,A.E., Maxson,R.E. Jr., Wilkie,A.O.M., Crump,J.G. and
            Twigg,S.R.F.
  TITLE     The developing mouse coronal suture at single-cell resolution
  JOURNAL   Nat Commun 12 (1), 4797 (2021)
   PUBMED   34376651
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2535)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2535)
  AUTHORS   Gongrich,C., Krapacher,F.A., Munguba,H., Fernandez-Suarez,D.,
            Andersson,A., Hjerling-Leffler,J. and Ibanez,C.F.
  TITLE     ALK4 coordinates extracellular and intrinsic signals to regulate
            development of cortical somatostatin interneurons
  JOURNAL   J Cell Biol 219 (1) (2020)
   PUBMED   31676717
REFERENCE   6  (bases 1 to 2535)
  AUTHORS   Claessens,A., Weyn,C. and Merregaert,J.
  TITLE     The cytoplasmic domain of chondrolectin interacts with the
            beta-subunit of Rab geranylgeranyl transferase
  JOURNAL   Cell Mol Biol Lett 13 (2), 250-259 (2008)
   PUBMED   18161010
  REMARK    GeneRIF: The function of chodl was investigated by searching for
            its protein interaction partners.
REFERENCE   7  (bases 1 to 2535)
  AUTHORS   Shou,S., Scott,V., Reed,C., Hitzemann,R. and Stadler,H.S.
  TITLE     Transcriptome analysis of the murine forelimb and hindlimb autopod
  JOURNAL   Dev Dyn 234 (1), 74-89 (2005)
   PUBMED   16059910
REFERENCE   8  (bases 1 to 2535)
  AUTHORS   Weng,L., Hubner,R., Claessens,A., Smits,P., Wauters,J.,
            Tylzanowski,P., Van Marck,E. and Merregaert,J.
  TITLE     Isolation and characterization of chondrolectin (Chodl), a novel
            C-type lectin predominantly expressed in muscle cells
  JOURNAL   Gene 308, 21-29 (2003)
   PUBMED   12711387
REFERENCE   9  (bases 1 to 2535)
  AUTHORS   Weng,L., Smits,P., Wauters,J. and Merregaert,J.
  TITLE     Molecular cloning and characterization of human chondrolectin, a
            novel type I transmembrane protein homologous to C-type lectins
  JOURNAL   Genomics 80 (1), 62-70 (2002)
   PUBMED   12079284
REFERENCE   10 (bases 1 to 2535)
  AUTHORS   Reymond,A., Friedli,M., Henrichsen,C.N., Chapot,F., Deutsch,S.,
            Ucla,C., Rossier,C., Lyle,R., Guipponi,M. and Antonarakis,S.E.
  TITLE     From PREDs and open reading frames to cDNA isolation: revisiting
            the human chromosome 21 transcription map
  JOURNAL   Genomics 78 (1-2), 46-54 (2001)
   PUBMED   11707072
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114925.6 and AC161815.4.
            
            On Dec 20, 2022 this sequence version replaced NM_139134.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140910.1, AF311699.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-500               AC114925.6         18922-19421         c
            501-810             AC114925.6         8835-9144           c
            811-968             AC114925.6         8565-8722           c
            969-1055            AC114925.6         5712-5798           c
            1056-1158           AC114925.6         3606-3708           c
            1159-1170           AC114925.6         1-12                c
            1171-2535           AC161815.4         87990-89354         c
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 45.39 cM"
     gene            1..2535
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /note="chondrolectin"
                     /db_xref="GeneID:246048"
                     /db_xref="MGI:MGI:2179069"
     exon            1..500
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /inference="alignment:Splign:2.1.0"
     CDS             422..1243
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; transmembrane protein MT75"
                     /codon_start=1
                     /product="chondrolectin isoform 1 precursor"
                     /protein_id="NP_624360.2"
                     /db_xref="CCDS:CCDS28279.1"
                     /db_xref="GeneID:246048"
                     /db_xref="MGI:MGI:2179069"
                     /translation="MIRIASLLLGAALLCAQGAFARRVVSGQKVCFADVKHPCYKMAY
                     FHELSSRVSFQEARLACESEGGVLLSLENEAEQKLIESMLQNLTKPGTGISDGDFWIG
                     LLRSGDGQTSGACPDLYQWSDGSSSQFRNWYTDEPSCGSEKCVVMYHQPTANPGLGGP
                     YLYQWNDDRCNMKHNYICKYEPEIHPTEPAEKPYLTNQPEETHENVVVTEAGIIPNLI
                     YVIIPTIPLLLLILVALGTCCFQMLHKSKGRSKTSPNQSTLWISKSTRKESGMEV"
     exon            501..810
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /inference="alignment:Splign:2.1.0"
     exon            811..968
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1055
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1158
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..2535
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2510..2515
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /note="hexamer: AATAAA"
     polyA_site      2535
                     /gene="Chodl"
                     /gene_synonym="3110074E07Rik; MT75; PRED12"
                     /note="major polyA site"
ORIGIN      
        1 ggctgttgct gctgttgctg ctgctgttgc tgctgttgaa gccactacca ggacacacca
       61 gctcagtccc ttagaacaca gagacctgag aaggaaggga aggcagctgc ttaggtttgc
      121 gttagaactc ccgtttcacc tttccaacag atacagacag aggaactcat aacactgtcc
      181 cctgctccca gacacgccca cggtgtcctg cactccagcc cagtgcggca cggggcagcc
      241 tggcagaagg tcctccctaa aggcgatgct tacaggcatc ctagctgctg cgctgggaag
      301 gagggagtag gacccagcag gaaagcaagg aagctgctgg tgagagccac cggcggtggc
      361 cgcgctgcgg gaagacctcg tctttccttc actggacacc tgctgcagaa ggctcgccag
      421 gatgatccgc atcgcctcac tcttgctggg agctgcgctg ctctgtgccc agggagcctt
      481 tgcccgaagg gtggtcagtg gtcaaaaggt gtgttttgct gatgtgaaac atccctgcta
      541 caaaatggcg tacttccatg aactgtctag ccgggtgagc ttccaggaag caaggctggc
      601 ttgtgaaagt gaagggggtg tcctcctgag tcttgagaat gaagctgaac agaagttaat
      661 agagagcatg cttcagaacc tgacaaaacc cggaacaggt atttcagatg gtgacttctg
      721 gataggactt ttgagaagcg gagatggcca aacatcgggt gcctgcccag atctctacca
      781 gtggtctgat ggaagcagct cccagttccg aaactggtac actgatgaac cttcttgtgg
      841 gagtgaaaaa tgtgtagtca tgtaccacca accaactgcc aatcctggcc taggaggtcc
      901 ctacctttac cagtggaatg acgacaggtg caacatgaag cacaattaca tctgcaagta
      961 tgaaccagag attcatccaa cagagcccgc tgaaaagccg tatcttacaa accaacctga
     1021 agagacccat gaaaatgtgg ttgttactga agcaggcata attcccaatc taatctatgt
     1081 tattatacca acgattccgc tgctcttact gatactggtt gctttgggaa cctgctgttt
     1141 ccagatgttg cataaaagta aaggaagatc aaaaactagc ccgaatcagt ctacactgtg
     1201 gatttcaaaa agcacgagga aggaaagtgg catggaggta taataatgaa ctggcattgt
     1261 tctggaaaaa taaaatagtt ttgtaatcgt tgatcaatgt aaggaatggc atcatcacct
     1321 tggaatggct tgaaatctca aaggatctgc aagatggact gtaagctccc ccttgaggca
     1381 aatgtcaaaa taatttttag aagtttatag tttcacttac aacatatgct gagtgagacc
     1441 tggttactct cctaaaggat acacctaaat ttcatgtaaa agaaatggac catgcggata
     1501 taatttctgt ggaccaatct ggaatacctg tgttgggagt agttactctt gctctctttc
     1561 ttttttcatc ttcataaatt ttgatctatg tcatgtaata taaattgtat ttcaatttac
     1621 ggtgtgcaga aacattctac ctttgcaaaa gtgtttgatg aaaatagagt gttctgatat
     1681 ttatatttat gacatttgat ttttacatat atagtgtttt cattaaaaac tgaattcaca
     1741 cagacacaaa gaaatccttg catagggaaa acatttcttt ggtaggatag ttcatgtttg
     1801 ttctgtttct ttgctttggg ttcgataaag tttaggaagt atcttcagaa ataagaaact
     1861 atttcattga ctgtgctgtt aatctgctga aacactttac ttagaggcaa gaactgtcta
     1921 acttcaattg tgcaagacac gtgccttaca attattctta atttaaaatt aaacagattt
     1981 ttgtaataaa gtatctttaa taatacttgt atagacacca atagagttaa ccttgaaaaa
     2041 aatggcatct gcagtacaaa tcacaggtct tcacatgttg cctatagaat tgcaaatagc
     2101 tccccagagt gtcaggaatc aatgtggctc ctccctttca atcaaacaga gtaactattt
     2161 gaaggctttg gagtcagaca gttgctgttt ggctgaggtt ctcctaactg aatttagcct
     2221 gtataatata taaagctcaa tggtttccag cagtgtgatg ctaagcagaa cacactgata
     2281 ttaatgatta aaagaagaag aagaagaaaa acaaaactac aaatcacatc atttaatggg
     2341 ccagggactc gaggttgctg atgtttgctt atctttgatg agtgttgttt gtggttgtga
     2401 actgtggctt ccttctgtct gatggagttt cctcaacacg tagcacttgt tcttctcaag
     2461 agagttgtaa ctattttgtc ttcaaatgtc cctgtgtcac ttttagccaa ataaagagtt
     2521 cttgtttctg aagaa
//
