LOCUS       NM_134078               2706 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus charged multivesicular body protein 7 (Chmp7), mRNA.
ACCESSION   NM_134078
VERSION     NM_134078.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2706)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2706)
  AUTHORS   Hermosilla Aguayo,V., Martin,P., Tian,N., Zheng,J., Aho,R., Losa,M.
            and Selleri,L.
  TITLE     ESCRT-dependent control of craniofacial morphogenesis with
            concomitant perturbation of NOTCH signaling
  JOURNAL   Dev Biol 503, 25-42 (2023)
   PUBMED   37573008
REFERENCE   3  (bases 1 to 2706)
  AUTHORS   Malik,B., Devine,H., Patani,R., La Spada,A.R., Hanna,M.G. and
            Greensmith,L.
  TITLE     Gene expression analysis reveals early dysregulation of disease
            pathways and links Chmp7 to pathogenesis of spinal and bulbar
            muscular atrophy
  JOURNAL   Sci Rep 9 (1), 3539 (2019)
   PUBMED   30837566
  REMARK    GeneRIF: Gene expression analysis reveals early dysregulation of
            disease pathways and links Chmp7 to pathogenesis of spinal and
            bulbar muscular atrophy.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2706)
  AUTHORS   Wollert,T., Wunder,C., Lippincott-Schwartz,J. and Hurley,J.H.
  TITLE     Membrane scission by the ESCRT-III complex
  JOURNAL   Nature 458 (7235), 172-177 (2009)
   PUBMED   19234443
REFERENCE   5  (bases 1 to 2706)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   6  (bases 1 to 2706)
  AUTHORS   Azmi,I., Davies,B., Dimaano,C., Payne,J., Eckert,D., Babst,M. and
            Katzmann,D.J.
  TITLE     Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a
            conserved VSL region in Vta1
  JOURNAL   J Cell Biol 172 (5), 705-717 (2006)
   PUBMED   16505166
REFERENCE   7  (bases 1 to 2706)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY129213.1, BC033365.1, BB621791.1, DV645139.1 and AK031882.1.
            
            On Mar 24, 2009 this sequence version replaced NM_134078.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.271020.1,
                                           SRR1660817.227766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BY129213.1         2-30
            30-1041             BC033365.1         1-1012
            1042-1201           BB621791.1         175-334
            1202-1878           DV645139.1         10-686
            1879-2706           AK031882.1         180-1007
FEATURES             Location/Qualifiers
     source          1..2706
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 36.09 cM"
     gene            1..2706
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /note="charged multivesicular body protein 7"
                     /db_xref="GeneID:105513"
                     /db_xref="MGI:MGI:1913922"
     exon            1..380
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            381..552
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            553..738
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            739..872
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            873..921
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1041
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1140
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1201
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1384
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1385..2706
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2666..2671
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2685
                     /gene="Chmp7"
                     /gene_synonym="4930596K11Rik; 6330407G04Rik"
                     /note="major polyA site"
ORIGIN      
        1 gacggaagcc gagagggacc tggggcggaa ggggacccgg gccaggcttg tgttcggttc
       61 cttggcgggg ctggggttcc gatgtggtcc ccggagcggg aggcccaggc cccgaccggg
      121 ggagacccgg cgggcctcct gccgcccgag tgggaggagg atgaggagcg catgtctttt
      181 ctgttctccg cctttaagag gagtcgcgag gtgaacagca ccgactggga cagcaagatg
      241 ggcttctggg ctccgttggt gctgagccac agccgccgcc aaggggtggt gcgcctgcga
      301 ctgcgggact tgcaggaggc cttccagcgc aagggcagtg tcccgctggg gctggctacg
      361 gtgctgcagg acctgctgcg tcgaggcgag ctgcagcgag agtcagactt catggccagt
      421 gtggacagca gctggatctc ctggggggtc ggcgtcttcc tgctgaagcc cctcaagtgg
      481 actctttcta acatgctggg ggatcacaaa gttccagcgg aggaggtgct ggtggctgtg
      541 gagctgctga aggaaaaggc cgaggaggtg tatcgcctat accagaactc gcccctctcc
      601 tcccaccctg tggtggccct gtcagagctg agtgctctgt gcgccaactc ctgcccggat
      661 gagaggacct tctacctcgt gctgctgcag ctgcagaagg agaagagagt cactgtcttg
      721 gagcagaatg gagagaagat tgtgaagttt gccaggggac cacatgccaa ggtatctcct
      781 gtgaacgacg tggatgttgg ggtctaccag ctgatgcaga gtgagcagct cctctctcgg
      841 aaggtcgagt ctttatccca agagtctgag aggtgcaaag aggaagcccg ccgggcatgc
      901 cgagcaggaa agaagcagct ggcactgagg tctctcaagg ccaagcagag gacagagaaa
      961 cgcattgagg ccctgcatgc caagctggac actgttcaag gcatcctgga tcgcatctat
     1021 gcctcccaga ctgatcagat ggtttttaat gcctaccaag ctggtgtggg agccttgaaa
     1081 ctctccatga aggatgtcac agtggagaaa gcagagagcc ttgtggatca gatccaggag
     1141 ctttgtgaca cgcaagatga agtttctcag actctggctg gtggagtaac caatggttta
     1201 gattttgaca gtgaggaact ggagaaggag ttggacatcc tccttcagga caccaccaca
     1261 gaacctttga gcctgctcga aaccccccag gagacaacgc tttataccaa cagtgtgcct
     1321 aagcctagga tcttggatgc tgaacttgaa gctgaacttg agaaattgtc attatcagaa
     1381 ggaggtttga tcccaagcag taaatctcca aaaaggcaat tggagccaac tctctaaagc
     1441 cattgcagga actcaagtga aggaccctca tgtatcagag aggcagcctt gcgcgtgtac
     1501 atagttattt aatgagaaac actgagaagt cgttggaaga ggagggaaga accacttgga
     1561 tgtatctgga tgctgctgct cacgccaaga cagatacagc ttctggaagc catgctatga
     1621 aggtgtgctc ccagtgatgt catggaccta ccttctcgtc tttatagtgc cacaatttat
     1681 acagttctgt gtttgacccg tcgtcttcat agcctgcagt tcttgccatt ggctccgtta
     1741 ggtttgtctt cacccaccag cttcattcca gccagtgaag gtgaaaggtt tgcagctctg
     1801 cccatctaag ctagccctct cttccactcg tgaggtcttt aaactgctcc cctagcctgt
     1861 gcttttctgg gaatgggagt caaacaagtt ttattcagag agacccaaca gctgagtctg
     1921 gagaaacact gtccggaaga tggttctcta cattcttcgt cacagtctgg gtattcgagg
     1981 ctctgaatgg ttcagggtca tggcagtttc cagggtggct tatgtgattg ggggccacaa
     2041 ccgcttccat cttagaagta gatctgctga tggagtgggg gaaaggatta atctgccttt
     2101 tcaaggtgag catgagaaac acaaacccta ggccccgggg tgtgaaagaa gctggattca
     2161 tgatttggcc ccattataaa ggatgtgttt tctggagcaa gccactgggc accacatcac
     2221 cctcaactgg ctccctccct gttaggatct ggaaagtgtc ttatctagta tccaccactc
     2281 agggcagggg cctgagccag gatgtgcaat aagaggcagg gcgctgacct gccgcatctg
     2341 ctgcgtgctg cctcctgccg gccagcacat ctgtgactcc aggaactgta ggacaggcag
     2401 aagtagatct gaatgctctg ggggcagcat ggagaagaga catgacagcc acactgccag
     2461 tctgctgccc agggacggtg gctgcctgga cctctttgca ctggcccttc ctgcttgagg
     2521 tgacttgagc agaggggaga actttgcctc aggccaggag cacgaatcat tgttcaaaga
     2581 gtctctccca ctcagccttg gcaatggaaa tagctggggg tgaagaaaaa caatcactat
     2641 tttttctttt ttaatctggt aaataattaa aagagaaaaa caccaggttt tgttgttgtc
     2701 tattct
//
