LOCUS       NM_025921               5842 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus charged multivesicular body protein 1B2 (Chmp1b2),
            mRNA.
ACCESSION   NM_025921
VERSION     NM_025921.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5842)
  AUTHORS   Wollert,T., Wunder,C., Lippincott-Schwartz,J. and Hurley,J.H.
  TITLE     Membrane scission by the ESCRT-III complex
  JOURNAL   Nature 458 (7235), 172-177 (2009)
   PUBMED   19234443
REFERENCE   2  (bases 1 to 5842)
  AUTHORS   Azmi,I., Davies,B., Dimaano,C., Payne,J., Eckert,D., Babst,M. and
            Katzmann,D.J.
  TITLE     Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a
            conserved VSL region in Vta1
  JOURNAL   J Cell Biol 172 (5), 705-717 (2006)
   PUBMED   16505166
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669851.8, AK011297.1 and AL844897.5.
            
            On Dec 10, 2008 this sequence version replaced NM_025921.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.132213.1, BC016070.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                AL669851.8         27695-27747         c
            54-1249             AK011297.1         2-1197
            1250-5842           AL844897.5         46134-50726         c
FEATURES             Location/Qualifiers
     source          1..5842
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 47.62 cM"
     gene            1..5842
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="charged multivesicular body protein 1B2"
                     /db_xref="GeneID:67028"
                     /db_xref="MGI:MGI:1914278"
     exon            1..200
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..784
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="charged multivesicular body protein 1b-2; CHMP1b-2;
                     chromatin-modifying protein 1b-2"
                     /codon_start=1
                     /product="charged multivesicular body protein 1B2"
                     /protein_id="NP_080197.2"
                     /db_xref="CCDS:CCDS53171.1"
                     /db_xref="GeneID:67028"
                     /db_xref="MGI:MGI:1914278"
                     /translation="MSNMEKHLFNLKFAAKELNRNAKKCDKEEKAEKAKIKKAIQKGN
                     TEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDAT
                     LRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEA
                     GLDLNMELPQGQTGSVGASVASTEQDELSQRLARLRDQV"
     exon            201..298
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            299..445
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            446..514
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            515..622
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            623..666
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            667..739
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            740..5842
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1223..1228
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1251
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="major polyA site"
     regulatory      4372..4377
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4392
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
     regulatory      4855..4860
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4876
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
     regulatory      5813..5818
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      5842
                     /gene="Chmp1b2"
                     /gene_synonym="2610002M06Rik; 8430408J07Rik"
ORIGIN      
        1 tagctcgtgg gactccaccc accacgggtt ctaaaccgaa acaggaagtg ggctaggatc
       61 cctcgaaacc cgctacaacc gccaccctcc gcgcgcccaa gcgacccaca actcgcgggt
      121 ccagcccctg tcccgcgtgt tacctgcccc tccccctcct cccgcccggt gaactcgaga
      181 gatcatgtcg aacatggaga aacacttatt taacttgaag tttgctgcaa aagaacttaa
      241 taggaatgcc aagaagtgtg ataaagaaga aaaagctgaa aaggccaaga taaaaaaggc
      301 cattcagaag ggcaatacag aagttgcaag aatacatgct gaaaatgcaa tccgtcagaa
      361 aaaccaagca atcaatttct tgagaatgag tgctagggtt gatgctgtgg cagccagagt
      421 tcaaactgca gtaacaatgg gcaaggtgac aaaatccatg gcaggtgtag ttaaatctat
      481 ggatgctaca ttgaggagta tgaaccttga gaagatttct gccttaatgg acaaatttga
      541 acatcagttt gaaacattgg atgttcagac acagcaaatg gaagatacaa tgagtagcac
      601 tactaccctt acgacaccac agaaccaagt ggatatgctg ctccaggaaa tggcagatga
      661 agctggcctc gatctcaata tggaactacc acagggtcag acagggtctg ttggtgcaag
      721 tgttgcttct acagagcagg atgaactgtc acagaggctt gctcgtcttc gtgatcaagt
      781 gtaacttaaa taactggtgc ttctgttcct ccacatattt ctgagccatc atttgtgtgt
      841 gtgtctatag ataaggtgta ttccagttac aaaaacatca tacatgacag gatgtttgga
      901 catcatttct ataagatgct ttcttttgcc ttgtgtattt cacagtgcat tgcgaaattc
      961 caaggaattt ccacattggc agattttata gttctatata ttgtgtgtaa aagtgtgagg
     1021 gacatatttt tctagatgtc tttggcaaag ctagcattag ttttctgtat attatacatc
     1081 ttccgcaaat attagagcaa acatctagca ccaaagtaat gctaagtaaa gtaattttgt
     1141 cagaataatg tataaaggct ttgtttttac ttattgaaag taactttcaa ttattgtctg
     1201 tgatgaattt tgattttgta aaaataaaaa caggaaagca tgttcattta atatgttcgc
     1261 ataacccaga ccatcttatt ttaagtatca caagatagac tatacaattt ccatgggatt
     1321 tttgaaaatt atttctattt tgtatgtatg gttgttttgc ctgcatgtta aattgtgtac
     1381 tcacttgtgt gtctggtgcc tacagaggcc agaagaggac attggattcc ccaggaacta
     1441 gagctataga caattgggag ccaacatgtg gatactagaa ttcaaaccca tttcttctag
     1501 aagaccagcc agtgctctta actcctgagc catgtgtcta gcctctgttt tgtttcgttg
     1561 ctgttgttgt tttgcttgtt tattttagag acagggcaga aatatatagc ccagagttcc
     1621 ctgaaactca gtgagcctcc agcattggtc tctaagtata taccaccata cccagctcat
     1681 tttctatgat ttgggggtgg gggttgttat gcacattagt tattttttct gtttctatga
     1741 taaataaccg tgctcaaaag tgacttatgg aagaaagaaa gtattttggt ttatggttcc
     1801 agggaaatga gggctccatc atggtgggga ggtgtggcag caagagcagg tagctggtac
     1861 atgtttaatg acacacacaa agcagaaaga acaggctgcc agtgtaacag acctagaagc
     1921 tctcaaagcc agtgacatac ttcatttagt aaggttgcat atctccatac cttctccata
     1981 aggcaccacc aactgggaaa caattattca agtacatgag tctatggaaa aatgtctcgt
     2041 tcagaccact gcattcctct ccctggcttc catagactta tggccatatc ataatgcaaa
     2101 atgtatttac tctgatgctt aaagtgccca tggtctttct caatctcaat actatttgaa
     2161 atttcaaagt ccagcatatc ttgtgagact cgagacaatc tctagccact gataagatct
     2221 aaaagcaaat aatatacttc caacatacga tggcacaggt tacacattat cattttagaa
     2281 gggaggaagg gggacatgat gaggaaatac tggactacag agagactgaa agctcacaag
     2341 gcatacatat aagcaaatcc tgtagctcta tgtgggatgt ctgggactac tttccgaggg
     2401 tttggatggc ttaactcctc cagctttgct gcctgattta atagctcact ctctagtaac
     2461 atcttctacg ttagttactt ctctgttgct gcgattaagc accatgacca gaagcaattt
     2521 ataaatagaa gagtttattt tggcttacag ttccagaggg ataagaaagt gtgcaccatg
     2581 gcagggatgc atggtagcag gatcaggaag ccaagaaatc atgctttcta ttatgctgta
     2641 cacatgacgc agaaagagcc agctggaagt gtggcaagac actcccaatg cctgttgctg
     2701 gtggaataat tcctccaaca gagtttgtac aatgacctgt accataacct tcccaactgg
     2761 tgaacaaagt ttcaaatatg tgagcctata ggagactcat tcaattcaga acattatgta
     2821 aagagaaaca gagtaaatat ttacttggtt ttaatccact gtaaagttta aatcattata
     2881 gtttttagcc agtaatttaa tgatgactgt tcattaattt ttaagacctt ttaatggaca
     2941 atttattata taactaggaa aattctgcaa cattaatcca aagtttgtat tgggataccc
     3001 tagatatcca tagaagagat ttgatggaca aaagtattta tgacataaag aatgtgttct
     3061 ctgttggtat gaattaaata gtttctgttc ttttaacttg aataaaaaat tgttagattt
     3121 attactacca cttagctcca caactagctg ttcattcttt tatgttgcaa ccatgtcaga
     3181 cttacctttt aaaatattac tatcagggct gtaaagttaa tactaccatt tcaagaggat
     3241 ctgcctttgt gtctcagcag cacatcagtt acctcacaac atcctgtaaa tctgcctcct
     3301 ggggattcag tgacctttcc tggttcccac agggtacctg aactcatgtg tatagatgca
     3361 cacagacaca cacataattt ttaaaataaa gatatactgg acatggtcac acataccttt
     3421 aatctcagca ctcaggagac tgaggctgtg agttccaggc cagccgaaga tacattatga
     3481 gaccacatct caaaaaatat ttgtaaaaca ttgatgaggc aggtaagata gttgagtaga
     3541 tataagcact tgccaccaag cctggcaacc tgagttcagt tcctgtgacc cacatggtag
     3601 atgtaaagat ttgctcctgc aaactgtcct ctgacctcca cacacattcc attgcatgca
     3661 cacaagtttt aaaattagaa actacattaa tggacactaa gttttatttt tcccttcatt
     3721 tgttcactct tttatcaatg taatgaaaat gtacctctta gactttattc ctaaaccaat
     3781 aacctaagca tgtgatggta tcatttggtt gaacatatat actcagatac ttaaaacatc
     3841 ttgttgcact ttcccctgtt ggataaaaag gctgatgata attctccatt tctttatgtg
     3901 tcttaatgct taaagccatc tggttgcctg tgaaccattt taggtaccat tatggactag
     3961 gctattttac ctggttaatt gattgcttac aaataccact tggagaagaa ggaatgagta
     4021 actctgagaa gagatgtgga ctttagaaaa ttctcaggaa ggagcatctg tagtattggg
     4081 agaaagcaaa atgaaatgat agactggcag aagtaagctt gccagcttcc tatggattaa
     4141 taatgtttgt tgctaatgat gttgagataa actgagaaag cgtgccattt aaaaattcta
     4201 ataggaaata gagagatggc tcagagttaa gagtactgta cgctcttgca gcggacctgg
     4261 gttcagttcc caacacccac atggtggctc acaactgtcc aacccccctt tttaatgttt
     4321 atgggttttt gtgcacatat ggtgcatgat atgtgcactc agatatgcat gaataaatat
     4381 tttttgaagt tatattaact cctactattt tttcatggga tgatttcata gtgtattttt
     4441 tcacaatcat aatcattatt tgcctattca tttctctaat acttattgag agtgtacttg
     4501 ctatgtgcta tggcgatttg gttttgaaga ttgaagggag gcagggcaag aaattctcaa
     4561 ttaactacaa ttgaagatac taagtgatct ctacaagatc aggcctaact cacctgtgga
     4621 gctgaactct aggattttga ctactttctc tgttgcatag aataatggca ttcattgttc
     4681 acattgccac ctacaaacta aattatctta cctacttcca aaaatggaga gcatatgagg
     4741 aatggtcaac tccctgcatt gtcatgtgta ttcaaaacaa agttatttat catctactgt
     4801 tgtggaaaat gttatttggg agtttctacc ccaccttaga tcatttagtt cccaaataaa
     4861 agattccaaa tctctatatt tgtaataagc tttgtagtac tagagctggg cagatatcaa
     4921 ccctctgtgc tatttgttct acttcaccat cagtaatact gagacatcac ttgctctgtt
     4981 ctgcctggtc cactcctact ccaacagact ggccctcagg gctatgcatc cttgatttac
     5041 ccccttggtg ccttcttcct cctctctaca gaagccctgc ctaccattct tttgccctgc
     5101 tacaggcaat tttaaattaa agtagcaggg tttgcacaac aaaaactggt atttgtgaaa
     5161 attcacttga ggcaaataga ccttggggta cagaatttag cattacaata catagcagca
     5221 gaccaatcct caacaattta ctgtatttct gattttccac tatttggtat tccttagaga
     5281 tacctttcat gaaaatttct ttgaaataca cacactgtat caccaaatcc ttcagtatga
     5341 ccttatctaa attcagtaac tcaaatgcct cattctacca aaatatttga aatataacaa
     5401 gcccaagtaa cttttgaatg gagaagagat taacatggat aaagttggaa tggaattggg
     5461 agtctaaggc tgagtattgt gaaaggagtg cttgacatgg cctttggaaa gacgtgggag
     5521 gaatctgctg tagaaaagtt ttgtcagtct ctatggtaca taggctcggc tttagccctc
     5581 atacatgtga ttacttcaac ctttgtcagg ggtcagcaca atctgcctgt ttcatcttca
     5641 tcgcccacac ttgaaaacat cttaatgtct ttgtttttct tgtgagagaa ttagatctca
     5701 actatctcaa tatgtttgac aagccttagt gtacatttac acctgaattt gacatgtaaa
     5761 tagcatcttt gtcaaactgg agggaatgta aatgatggat atgtcagtgc tcaataaaca
     5821 gttctagaat gattatttga aa
//
