LOCUS       NM_024190               2529 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus charged multivesicular body protein 1B (Chmp1b), mRNA.
ACCESSION   NM_024190
VERSION     NM_024190.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2529)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2529)
  AUTHORS   Wollert,T., Wunder,C., Lippincott-Schwartz,J. and Hurley,J.H.
  TITLE     Membrane scission by the ESCRT-III complex
  JOURNAL   Nature 458 (7235), 172-177 (2009)
   PUBMED   19234443
REFERENCE   3  (bases 1 to 2529)
  AUTHORS   Azmi,I., Davies,B., Dimaano,C., Payne,J., Eckert,D., Babst,M. and
            Katzmann,D.J.
  TITLE     Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a
            conserved VSL region in Vta1
  JOURNAL   J Cell Biol 172 (5), 705-717 (2006)
   PUBMED   16505166
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140336.2.
            
            On Feb 25, 2010 this sequence version replaced NM_024190.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC034442.1, AK167614.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2529              AC140336.2         40495-43023         c
FEATURES             Location/Qualifiers
     source          1..2529
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 39.89 cM"
     gene            1..2529
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
                     /note="charged multivesicular body protein 1B"
                     /db_xref="GeneID:67064"
                     /db_xref="MGI:MGI:1914314"
     exon            1..2529
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..742
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
                     /note="charged multivesicular body protein 1b-1;
                     chromatin-modifying protein 1b-1; chromatin modifying
                     protein 1B"
                     /codon_start=1
                     /product="charged multivesicular body protein 1B1"
                     /protein_id="NP_077152.1"
                     /db_xref="CCDS:CCDS84391.1"
                     /db_xref="GeneID:67064"
                     /db_xref="MGI:MGI:1914314"
                     /translation="MSNMEKHLFNLKFAAKELNRSSKKCDKEEKAEKAKIKKAIQKGN
                     MEVARIHAENAIRQKNQGVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDAT
                     LKSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEA
                     GLDLNMELPQGQTGSVGTSVASAEQDELSQRLARLRDQV"
     regulatory      2429..2434
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
                     /note="hexamer: ATTAAA"
     polyA_site      2454
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
                     /note="major polyA site"
     regulatory      2507..2512
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
                     /note="hexamer: CATAAA"
     polyA_site      2529
                     /gene="Chmp1b"
                     /gene_synonym="2810405I11Rik; Chmp1b1"
ORIGIN      
        1 agagtttgac gtcaccgtct gcgccgcacg ccgtaataca ggaagtgaga ccaaaacaaa
       61 ggagcgccgg ccgggtgcgg accttcttgc accggtgtcc ctgctgcctc gcccgcgccc
      121 accccaccga agccgcacga cgatgtccaa catggagaag catctgttca acctgaaatt
      181 cgcggccaaa gaactgaacc ggagttccaa aaaatgcgac aaggaagaaa aggccgaaaa
      241 ggccaaaatt aaaaaggcca ttcagaaggg caacatggaa gttgcgagga ttcacgccga
      301 aaatgccatc cgccagaaga atcaaggggt gaacttcttg agaatgagtg cacgagtgga
      361 tgcggtggcg gcccgtgtcc agactgcagt gacgatgggc aaagtgacca agtccatggc
      421 gggtgtggtt aagtcgatgg acgcgacgtt gaaaagtatg aatctggaga agatctccgc
      481 tttgatggac aaattcgaac accagttcga gactctggac gtccagacgc agcaaatgga
      541 agacacaatg agcagcacga cgacgctgac cactccccag aaccaggtgg atatgctgct
      601 ccaggaaatg gcagatgagg cgggcctcga tctcaacatg gagctgcctc agggccagac
      661 cggttccgtg ggaacgagcg tggcttcggc tgagcaagat gaactgtccc agagactggc
      721 ccgccttcgg gatcaagtct gacggccgaa ccagtccgag atttcccttt gacgtgctct
      781 ctgtgtttta gagagatgtc ccagaattgt gccagaatgc cgaacggtct tctaagaacc
      841 tacagccctc accagataac gctgagaaat tccagttttt ctccacttct aactggattt
      901 taaagctctt tctagcttat gatgatgtgt atttttatag ctgcctttta acagaactgg
      961 ttcatttgct ctacataaat ctaggaaaaa atcgacagaa ctctagccct catgtattcc
     1021 gtttttactt agaattatca gactgaagtt atttttagtg tggttgatgg tacagagact
     1081 ggcaagcggt gcattaaaat gaaaggagaa ggaatgggta ctaacaagta tgtaaacact
     1141 ttgttcaact tcttcggtgg gaaatactct ttctgtatat catttggttt tctttgtttt
     1201 tgccttcaaa gaacgactgc aattgactta atttattctc ataacttata ctaaagttat
     1261 cttagaagat tattgcaaca tactctttac attctgttag ttcgtgtaat aatggagttt
     1321 gtgtaactgg gaaaatatgc caagtaactt catttattat caggagaaat taaaattttt
     1381 tgtttatatt ctatttacca agagttctta agcttaagat aatttctaat taagaaaatc
     1441 tctagttgtt ttctaatgaa agtcaaccct taatagactt ctgatcaaaa taatgttgaa
     1501 tgtcaacaca acagtcctat tacatgccaa acattgccaa agaaccgctg atttggtccg
     1561 gccaagccct aggacagtgt aattacaggt tttgttttat ttaataacaa ataatataaa
     1621 taaaattaga acagcatttt taagttctat ttgtatgtat tattttgtcc taaagcaaca
     1681 actcttttaa aatctcaaaa agcataagtt aatgctatag atatacagaa cttaactgta
     1741 catttagcca gctagaagtc tagagcaaag cagtgagctg ggattagaag gaaagagagg
     1801 ctgaaagtag ctgccttcct ttatagcctc tggtgtaaaa caaagcaact cccactttct
     1861 tctatcctca aaacacagag aacagcttgt gtttgcttgg cacatatatt aacctaagtt
     1921 aaatacttac aaagtttgtt ttatttaatt tccccttttc ctgatttttg ttttgttttt
     1981 ccattaagag aattccaatg tttcaaacaa gatagagcct ctggaaaact ctttgaaaaa
     2041 ttcattatta tgtgaattgt atggtttccc aggtgaacga gtgtttaatg aacaaagtgt
     2101 aatcgtacag agatgaatac tgactctcgg agttaaggag tgtgtggggg tgagcacatt
     2161 tgcacacata tatacacata gttttttctt aagtctgctc tgtgggacac ttctaactgc
     2221 ccagtgtcct ctctcaaagg tcctttagca gatatgtgac ttctcatata cacagttacg
     2281 ctaactcagg tgtatgatga atacagtgta tgttttaatc ctttatcctg gaaaaccttg
     2341 gttaagtaca gctttaaaaa ataactcagt attgactcct cggtaaattt tgtactgcaa
     2401 gcatttccac cagattatat tttatgagat taaagaatgc tatatatgct taaaccttct
     2461 taaaatgtgt tcatttcata ctatatggat atacatttat atgagtcata aacattattt
     2521 tcaaaagcc
//
