LOCUS       NM_007697               7751 bp    mRNA    linear   ROD 21-MAY-2024
DEFINITION  Mus musculus cell adhesion molecule L1-like (Chl1), mRNA.
ACCESSION   NM_007697
VERSION     NM_007697.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7751)
  AUTHORS   Fernandes,L., Kleene,R., Congiu,L., Freitag,S., Kneussel,M.,
            Loers,G. and Schachner,M.
  TITLE     CHL1 depletion affects dopamine receptor D2-dependent modulation of
            mouse behavior
  JOURNAL   Front Behav Neurosci 17, 1288509 (2023)
   PUBMED   38025382
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7751)
  AUTHORS   Moreau,M.X., Saillour,Y., Elorriaga,V., Bouloudi,B., Delberghe,E.,
            Deutsch Guerrero,T., Ochandorena-Saa,A., Maeso-Alonso,L.,
            Marques,M.M., Marin,M.C., Spassky,N., Pierani,A. and Causeret,F.
  TITLE     Repurposing of the multiciliation gene regulatory network in fate
            specification of Cajal-Retzius neurons
  JOURNAL   Dev Cell 58 (15), 1365-1382 (2023)
   PUBMED   37321213
REFERENCE   3  (bases 1 to 7751)
  AUTHORS   Maejima,I., Hara,T., Tsukamoto,S., Koizumi,H., Kawauchi,T.,
            Akuzawa,T., Hirai,R., Kobayashi,H., Isobe,I., Emoto,K., Kosako,H.
            and Sato,K.
  TITLE     RAB35 is required for murine hippocampal development and functions
            by regulating neuronal cell distribution
  JOURNAL   Commun Biol 6 (1), 440 (2023)
   PUBMED   37085665
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7751)
  AUTHORS   Shibata,M., Pattabiraman,K., Lorente-Galdos,B., Andrijevic,D.,
            Kim,S.K., Kaur,N., Muchnik,S.K., Xing,X., Santpere,G., Sousa,A.M.M.
            and Sestan,N.
  TITLE     Regulation of prefrontal patterning and connectivity by retinoic
            acid
  JOURNAL   Nature 598 (7881), 483-488 (2021)
   PUBMED   34599305
REFERENCE   5  (bases 1 to 7751)
  AUTHORS   Moreau,M.X., Saillour,Y., Cwetsch,A.W., Pierani,A. and Causeret,F.
  TITLE     Single-cell transcriptomics of the early developing mouse cerebral
            cortex disentangle the spatial and temporal components of neuronal
            fate acquisition
  JOURNAL   Development 148 (14) (2021)
   PUBMED   34170322
REFERENCE   6  (bases 1 to 7751)
  AUTHORS   Montag-Sallaz,M., Schachner,M. and Montag,D.
  TITLE     Misguided axonal projections, neural cell adhesion molecule 180
            mRNA upregulation, and altered behavior in mice deficient for the
            close homolog of L1
  JOURNAL   Mol Cell Biol 22 (22), 7967-7981 (2002)
   PUBMED   12391163
  REMARK    GeneRIF: data show that the permanent absence of CHL1 results in
            misguided axonal projections and aberrant axonal connectivity and
            alters the exploratory behavior in novel environments, suggesting
            deficits in information processing in CHL1-deficient mice.
REFERENCE   7  (bases 1 to 7751)
  AUTHORS   Hortsch,M.
  TITLE     Structural and functional evolution of the L1 family: are four
            adhesion molecules better than one?
  JOURNAL   Mol Cell Neurosci 15 (1), 1-10 (2000)
   PUBMED   10662501
  REMARK    Review article
REFERENCE   8  (bases 1 to 7751)
  AUTHORS   Hillenbrand,R., Molthagen,M., Montag,D. and Schachner,M.
  TITLE     The close homologue of the neural adhesion molecule L1 (CHL1):
            patterns of expression and promotion of neurite outgrowth by
            heterophilic interactions
  JOURNAL   Eur J Neurosci 11 (3), 813-826 (1999)
   PUBMED   10103075
REFERENCE   9  (bases 1 to 7751)
  AUTHORS   Chen,S., Mantei,N., Dong,L. and Schachner,M.
  TITLE     Prevention of neuronal cell death by neural adhesion molecules L1
            and CHL1
  JOURNAL   J Neurobiol 38 (3), 428-439 (1999)
   PUBMED   10022583
REFERENCE   10 (bases 1 to 7751)
  AUTHORS   Holm,J., Hillenbrand,R., Steuber,V., Bartsch,U., Moos,M.,
            Lubbert,H., Montag,D. and Schachner,M.
  TITLE     Structural features of a close homologue of L1 (CHL1) in the mouse:
            a new member of the L1 family of neural recognition molecules
  JOURNAL   Eur J Neurosci 8 (8), 1613-1629 (1996)
   PUBMED   8921253
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK040765.1, X94310.1 and AC153595.27.
            
            On Jul 14, 2006 this sequence version replaced NM_007697.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.265123.1, X94310.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-187               AK040765.1         1-187
            188-2224            X94310.1           62-2098
            2225-2356           AK040765.1         2203-2334
            2357-4126           X94310.1           2231-4000
            4127-7751           AC153595.27        172333-175957       c
FEATURES             Location/Qualifiers
     source          1..7751
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 47.97 cM"
     gene            1..7751
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /note="cell adhesion molecule L1-like"
                     /db_xref="GeneID:12661"
                     /db_xref="MGI:MGI:1098266"
     exon            1..274
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            275..344
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            345..512
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     CDS             422..4051
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /note="neural cell adhesion molecule L1-like protein;
                     chl1-like protein; close homolog of L1; cell adhesion
                     molecule with homology to L1CAM"
                     /codon_start=1
                     /product="neural cell adhesion molecule L1-like protein
                     precursor"
                     /protein_id="NP_031723.2"
                     /db_xref="CCDS:CCDS39582.1"
                     /db_xref="GeneID:12661"
                     /db_xref="MGI:MGI:1098266"
                     /translation="MMELPLCGRGLILSLIFLLLKLSAAEIPLSVQQVPTIVKQSYVQ
                     VAFPFDEYFQIECEAKGNPEPIFSWTKDDKPFDLSDPRIIAANNSGTFKIPNEGHISH
                     FQGKYRCFASNRLGTAVSEEIEFIVPGVPKFPKEKIEPIDVEEGDSIVLPCNPPKGLP
                     PLHIYWMNIELEHIEQDERVYMSQRGDLYFANVEENDSRNDYCCFAAFPKLRTIVQKM
                     PMKLTVNSSNSIKQRKPKLLLPPAQMGSLSAKTVLKGDTLLLECFAEGLPTPHIQWSK
                     PGSELPEGRATIEVHEKTLKIENISYQDRGNYRCTANNLLGKASHDFHVTVEEPPRWK
                     KKPQSAVYSTGSSGILLCEAEGEPQPTIKWRLNGLPIEKHPFPGDFMFPREISFTNLL
                     PNHTGVYQCEASNIHGTILANANIDVIDVIPLIKTKNEENYATVVGYSAFLHCEYFAS
                     PKATVVWEVADETHPLEGDRYHTHENGTLEIYRTTEEDAGSYSCWVDNAMGKAVITAN
                     LDIRNATKLRVSPKNPRIPKSHVLELYCESQCDSHLKHSLKLSWSKDGEAFEMNGTED
                     GRIVIDGAYLTISNITAEDQGVYSCSAQTSLDSTSEKTQVTVLGVPDPPGNLHLSERQ
                     NRSVRLSWEAGDDHNSKISEYIVEFEGNREEPGKWEELTRVQGEETDVVLSLAPYVRY
                     QFRVTAVNEVGRSHASLPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQ
                     NGPGLEYKVSWKPQGAPEEWEEEIVTNHTLRVMTPTVYAPYDVKVQAINQLGSSPDPQ
                     PVTLYSGEDYPSTAPVIQRVDVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLL
                     DGRTHPKEVNILRFSGQRNSGMVPSLDPFSEFHLTVLAYNSKGAGPESEPYIFQTPEG
                     VPEQPSFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYELGELNEINVTT
                     PSKSSWHLSNLNSTTKYKFYLRACTSRGCGKPISEEGATLGEGSKGIRKITEGVNVTQ
                     KIHPVEVLVPGAEHIVHLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLM
                     CAIALLTLILLTICFVKRNRGGKYSVKEKEDLHPDPEVQSAKDETFGEYSDSDEKPLK
                     GSLRSLNRNMQPTESADSLVEYGEGDQSIFNEDGSFIGAYTGAKEKGSVESNGSSTAT
                     FPLRA"
     exon            513..618
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            619..806
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            807..929
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1100
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1221
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1406
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1538
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1679
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1791
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..1958
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1959..2124
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2249
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2250..2351
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2352..2549
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2550..2620
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2843
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2844..2959
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            2960..3164
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3165..3287
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..3467
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3468..3629
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3630..3761
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3762..3834
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            3835..7751
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4523..4528
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /note="hexamer: ATTAAA"
     polyA_site      4544
                     /gene="Chl1"
                     /gene_synonym="A530023M13Rik; CALL; LICAM2"
                     /note="major polyA site"
ORIGIN      
        1 agctagtcgt ctccggcagg agggcgtgga taccggtaca agctcgaaca ggtccagcct
       61 tctggagacc tgtgccaaca gcaggagggg gcagacggga tctctgtggg cagatcgggg
      121 tgtggatcag cgggaagcgc ccaactagaa actcccttgg attctccaag aggcgctgga
      181 cctcgttggt cccctttgcc ccagtgatcc agctttagga gaagttttcc caagagaagg
      241 taccagacag atcggatgtc aagaggcggc tcaggtgtta tagactgcag gcaatgattc
      301 taccttgata atccaggcag accaccgtgg atcaaaaatt cctggtttct cccatttcct
      361 cagtgaacag aaagtattag agaccctttc cagtctttgc acgttgcctc ctttctgagg
      421 aatgatggaa ttgccattat gtggaagagg actgatccta agtctaattt tcctcctgtt
      481 aaaattgtca gcagctgaaa taccactctc cgttcaacag gttccaacaa ttgtaaagca
      541 gtcatacgtg caggtggcct ttcccttcga tgagtatttt caaattgaat gtgaagcgaa
      601 aggaaaccct gaaccaatat tttcatggac taaggacgat aagccttttg atctttctga
      661 tcctcggata attgcggcta acaattcagg cacattcaag atcccaaatg agggccacat
      721 ctctcacttt caaggaaaat accgctgttt cgcatccaat agactaggaa ctgcagtatc
      781 agaagaaata gagttcatag taccaggggt tccaaaattc ccaaaagaaa aaattgaacc
      841 cattgatgta gaagaagggg attccattgt cttaccctgc aaccctccaa aaggcctccc
      901 acctttgcac atctattgga tgaatattga gttagaacac attgaacaag atgagagagt
      961 atacatgagc caaagaggag atctgtactt tgcaaatgtg gaagaaaatg acagtcggaa
     1021 tgattactgt tgcttcgctg catttccaaa attaagaacg attgtacaga aaatgccaat
     1081 gaaactgact gtgaacagtt caaattccat caagcaaagg aaacccaaac ttctgttgcc
     1141 tcctgcccaa atgggaagtt tatctgcaaa gactgtactc aaaggggata cactattgct
     1201 cgagtgtttt gcggagggcc taccaactcc acatatccag tggagcaaac caggtagtga
     1261 attaccagag ggaagagcaa caattgaagt tcatgaaaag acattgaaga tagaaaacat
     1321 ctcctaccag gatagaggaa attatcgctg tacagccaac aatttgttgg ggaaagccag
     1381 tcatgatttt cacgtcacag tagaagagcc tccacgctgg aaaaagaagc ctcagagtgc
     1441 cgtgtacagc acggggagca gtggcatctt gttgtgtgaa gcagaaggcg aacctcaacc
     1501 cacaatcaaa tggagactca atggcttgcc gattgaaaaa catccatttc ctggtgactt
     1561 tatgttcccc agggaaatca gttttacaaa cttactgcca aatcatactg gtgtatatca
     1621 gtgtgaagcc tcaaatattc acggaaccat tctggccaat gccaatattg acgttataga
     1681 tgttatccca ctgataaaaa ctaagaatga agaaaactac gcgacagtgg ttggctacag
     1741 cgctttctta cactgcgagt actttgcttc tcccaaggcc accgtggtct gggaagtggc
     1801 tgatgagaca catcccctgg aaggtgatcg gtaccatacg catgaaaacg gcacactgga
     1861 gatctacaga actactgagg aggatgcggg gtcctactct tgttgggtag acaatgccat
     1921 gggaaaagcc gtcatcacag cgaacttgga tattagaaat gctacaaagc tcagagtttc
     1981 tcctaagaat cctcgaatcc ctaaatcaca tgtgcttgaa ctatactgcg aaagccagtg
     2041 tgactcacat ttgaaacaca gtttgaagtt gtcctggagt aaagatggag aagcttttga
     2101 gatgaatggc acagaagatg gcagaatagt gattgacgga gcttacctga ccatatctaa
     2161 catcacagca gaagatcagg gtgtttactc ctgttctgct caaacttctc ttgatagtac
     2221 ttcggaaaaa actcaagtaa ccgtccttgg tgttccagat ccgccaggaa accttcactt
     2281 gtcagaaaga caaaacagaa gtgtccggct gtcctgggaa gcaggagatg accacaacag
     2341 caaaatcagc gagtacattg tagaatttga agggaacaga gaggagcctg gaaagtggga
     2401 ggagctaact agagtccagg gagaagaaac agatgtcgtg ttatctttgg ctccttatgt
     2461 gagatatcag tttagggtca cagctgtaaa cgaagtcgga agaagccacg ccagcctgcc
     2521 ttcagaccat catgaaactc caccagcagc tccagacaag aatccccaga acatcagagt
     2581 tcaagcatct caacccaagg aaatgattat aaaatgggag cctttgaaat ccatggaaca
     2641 gaatgggcca ggactggagt acaaagtgag ctggaagccc cagggagccc ccgaagagtg
     2701 ggaagaagaa atagttacaa accacacact acgtgtgatg acacctactg tctatgctcc
     2761 ttatgatgtc aaggtccaag ccatcaatca actaggctcc agccctgacc ctcagccagt
     2821 gacactctat tcaggggaag actatcctag tacagcccct gtgatccagc gtgtggatgt
     2881 tatgaacagt acattagtta aagttacctg gtcatccatt cctaaggaaa cagtacacgg
     2941 acttctaaga gggtaccaga taaattggtg gaaaaccaaa agcctgttgg atggaaggac
     3001 acatcccaaa gaagtaaaca ttctaaggtt ttcaggacag cgaaactctg gaatggttcc
     3061 ttccctagac ccctttagtg aatttcactt aacagtctta gcctataact ccaaaggagc
     3121 tggtccagag agcgagcctt atatatttca gacaccagaa ggagtacctg aacaaccaag
     3181 ttttctcaag gtcatcaaag ttgataaaga cactgccacc ttatcctggg gccttcctaa
     3241 gaaactaaat ggaaatttaa ctggttatct cttacaatac cagataataa atgacaccta
     3301 cgagcttgga gagttaaatg aaatcaacgt tactactcca tctaaatcca gctggcatct
     3361 ctccaacctc aactcaacaa caaaatacaa attctacctg agggcgtgca cctcaagagg
     3421 ctgtggaaag ccaataagtg aagaaggtgc caccctagga gaagggagta aaggtatcag
     3481 gaagataaca gaaggagtaa atgttaccca aaagattcac cctgtagagg tacttgtgcc
     3541 gggagcggaa catattgttc acctaatgac taagaattgg ggtgataacg atagcatttt
     3601 tcaagatgta attgagacaa gagggagaga atatgctggc ttatatgatg acatctccac
     3661 tcaaggctgg tttattggac tgatgtgtgc aattgctctt cttacactga tattgttaac
     3721 tatttgcttt gtgaagagga acagaggtgg aaagtattca gtaaaagaaa aggaagattt
     3781 acacccagat ccagaagttc agtcagcaaa agatgaaact tttggtgaat acagcgacag
     3841 tgatgaaaaa cctctcaagg gaagccttcg gtccctgaat aggaacatgc agcccacaga
     3901 gagtgctgac agtttagtgg aatatggaga gggagaccag tccatattca acgaagatgg
     3961 atcgtttatt ggcgcataca ctggagctaa ggagaaggga tccgttgaaa gcaatggaag
     4021 ttcaactgcc accttcccac tccgggcatg agaacaacac attcaggcac cacgggtggc
     4081 taagccggac aaggggagca aggcctttta cacaggagcg gaaacgcgtg tccagaggtt
     4141 gatattctgc aattttgatg aaagaaatag cactgccttc aaaaagaaaa agggaaaaaa
     4201 aatcagatgc caagaacttc agacttgtgt ttcattttgg gttttgattt caggtgctca
     4261 aaatgcagaa cacgaaacaa atcctgtact tagatccact ttgactgaat ccaaagttcc
     4321 catttcagat actccacatc tacctggctc tcctgttcag tgtgtgtgca ttgatgttgc
     4381 taagatgtgt gggtttctct ctggatgcac aattatactt agttttgaag aactgtttta
     4441 gtgaattcga ttcactacag gataaaagat tgtaagcaag caagctggtt atttaaaatg
     4501 taaaaaggaa catgattgtc ttattaaaca tcccgtggaa tctatacagt ctaaagttat
     4561 tatttaaaat tttagtagca aaagtcttag atgatcatac cactcatatt tattgagctc
     4621 ctaacttttt gcccagacaa aggccatctt tactcagatt acaatatttt cagtttctgg
     4681 atgattctgt ttaatttctg ttagtaatgg taactctgta tgtacctttc cctccctccc
     4741 tcccctccct cccctccctc cctccctctt tctttctttc tttctttctt tctttctttc
     4801 tttctttctt tctttctttc tttctttctt tctttctttc tttcttcttt caacttgaac
     4861 taactggagc tgcaaaggga gtggtagtca taagttattt taaaaagaga aagatgtaga
     4921 cgtcttgatt ttatatcttc atttgtaagt ttagggcttt cagcctttat gtttatatac
     4981 tgagaccctt gagtgtattt catgaatgca ttgtacatat tatgttaata tttacacagt
     5041 ttaaaacata gtgttttatt ttaaagtgag aaaaggaaca ttaataggca tgattgtaca
     5101 gctagaatat atatagtaag ataccatttt tattcttctg gggctagata caataacatg
     5161 aggttccata tacaagacta tatgaaaaat tggattctgt ccttatattt ccctccttca
     5221 tgtggtctca aaaataaaac attatataat catagaggga aatacattca tattttccaa
     5281 agtaagttgt ggaatggatt cctaccccag cactccaaaa agaaaattac ctacagtaga
     5341 aattcttata tacctgttag tttatatcat attgtaaatg tatttgtagt ggtatgatca
     5401 tttttaatgt tttccttcta tcaaagttag tacagattca gggattttaa tttctggcat
     5461 gtgggctacc agtccatcta aaatggtaca tagggtttag agcattttag aaatcccttg
     5521 aaggactctg catacatata agtaaatgtt aaatattagt atttcctttc acatttaatg
     5581 gaaacatttt agcttcacca tgaaattatt acatgttaag tgatattggt tcacagattt
     5641 aactttagtt tgtataatta ctgaccatat tattcattct tcatgtttaa ttggcataat
     5701 gcattgtgtt acttggggat ttaaattgtg gacatgcaaa agagccaatg cagtaataaa
     5761 catgaagcat atgttttgcc cacaggcatc ctcgagaatg cataggcagg aaaatcttgg
     5821 ttttgttttt gtttttaatt tttgtggatg tttcttgggg ttttgttttg attttttgtt
     5881 ttggttggtt ttgggtttgt ttgtttgttt gtttttaaaa cccatggatc tcagtattca
     5941 gttactctcc tggaagtacc aaatgaaagc gggtgtgagt gtaaggatcc agaagtccag
     6001 ctgtgtgagc agctctccag ccctttctga tgaccagggc acagatttct ggaaaatcca
     6061 tcactgtgtg ctatttttat gggaggacct gtagtgctga gccccagagg aaataatgga
     6121 tgtgactgac attaaacatg ttattattct gcctcctctt tatcatcaaa atgtgcctgg
     6181 aaaagggtta tataagtgga aaataacatc caaacgttca gaatagagtc attaggaatt
     6241 taataatctt cgagtgagaa gttgacacaa atacttatat ttccaatgga tctcatcatt
     6301 ctttccttag ctgtgggaat gggagattgg cttataacac cttttgctag cctctgtgaa
     6361 cttatacata ctatttggtt tcattccgtt gtaactcttc agcaaagcag gccaaggtcc
     6421 atggactttt tattttaatt atagaattat attacttact acattcaaat gaaaacaaat
     6481 ccaattggtt aaagtggatt ttattctttt actgtctcaa acaatgggtg gcagactctg
     6541 acgtgcaatg ctgactacaa tgggcaataa taattgtttg gaagatgccc actgagtcat
     6601 aaggcagctg ctagtgtgta caactttgtt cttaattggt ttcgcagtaa gattctatag
     6661 tctactgaca atatgatttt aatgtaagtg attgtatata atctcaagga ttgtcagcgg
     6721 ggataacttc agtgggagat gtttgagggt caggaaaatc tgtgttctct tccaggttcc
     6781 agcacatatt atatagagaa accataggca cgatgctgaa ctacttcact tcaaactgtg
     6841 ctacaaagtg ctaatgatcg ctatcacagg gtgttctttt gtacgaagaa aaatttacaa
     6901 gtgataaaat ctaagatgcc ttttaacctc atcaccaaac ctgtaatcaa attatgtatc
     6961 aaaaagtcac ccccacatac accaactcaa ctttcccccc ctctaagcac ataaatatat
     7021 ttttatagaa aacagatcta cagaaaataa acaaaatctg ctgttatgag aggagtacaa
     7081 tttgcacatg ccattgaaaa ttactaatca gaagaagatt aagcagggtc tttgctatac
     7141 aaaagcattt tccactaatt ctgcatgcat atttataaga cgtgaactca gtggatttat
     7201 tctcttggta taaaggcatc tgatatttta gatgtaccca tgtttataaa aagaaaatgt
     7261 agagcacaac ggacttatgc tattttatac tcatggaaga gatagaggac aataggagag
     7321 atgtcggctg cttttctaag tatttaaaac atatttgcca attgaaaccc taaatatgtt
     7381 tacatgccat gaaggcgtaa ctcttgtaac aactttaaat tggttataat aggactggtt
     7441 tgtggtctgt gatagtagat gtaccctagt gttcctatag tgagataagt agtgctgagc
     7501 caaagcttac tttgttttgt gtcttaaact gactgcattg tcaaaaagac aaaaggtaat
     7561 gggagcaggt tcaccctatt agcttttcct tccgtttttc tctgagacta atgttcacag
     7621 tagatcttta ttgaaatgtg tttgtgttgt agatggtgtt tgtattgtgc ttatggctat
     7681 gtatggttca aaactatttt cattacacat ggagttcagc tttcaaataa aagtttgact
     7741 tcgtgtactg t
//
