LOCUS       NM_001304362            7189 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus cingulin-like 1 (Cgnl1), transcript variant 1, mRNA.
ACCESSION   NM_001304362 XM_006511394
VERSION     NM_001304362.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7189)
  AUTHORS   Flinois,A., Mean,I., Mutero-Maeda,A., Guillemot,L. and Citi,S.
  TITLE     Paracingulin recruits CAMSAP3 to tight junctions and regulates
            microtubule and polarized epithelial cell organization
  JOURNAL   J Cell Sci 137 (5) (2024)
   PUBMED   37013686
  REMARK    GeneRIF: Paracingulin recruits CAMSAP3 to tight junctions and
            regulates microtubule and polarized epithelial cell organization.
REFERENCE   2  (bases 1 to 7189)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7189)
  AUTHORS   Ahuja,N., Hiltabidle,M.S., Rajasekhar,H., Voss,S., Lu,S.Z.,
            Barlow,H.R., Cowdin,M.A., Daniel,E., Vaddaraju,V., Anandakumar,T.,
            Black,E., Cleaver,O. and Maynard,C.
  TITLE     Endothelial Cyp26b1 restrains murine heart valve growth during
            development
  JOURNAL   Dev Biol 486, 81-95 (2022)
   PUBMED   35364055
REFERENCE   4  (bases 1 to 7189)
  AUTHORS   Yuan,Y., Loh,Y.E., Han,X., Feng,J., Ho,T.V., He,J., Jing,J.,
            Groff,K., Wu,A. and Chai,Y.
  TITLE     Spatiotemporal cellular movement and fate decisions during first
            pharyngeal arch morphogenesis
  JOURNAL   Sci Adv 6 (51) (2020)
   PUBMED   33328221
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7189)
  AUTHORS   Chrifi,I., Hermkens,D., Brandt,M.M., van Dijk,C.G.M.,
            Burgisser,P.E., Haasdijk,R., Pei,J., van de Kamp,E.H.M., Zhu,C.,
            Blonden,L., Kros,J.M., Duncker,D.J., Duckers,H.J. and Cheng,C.
  TITLE     Cgnl1, an endothelial junction complex protein, regulates GTPase
            mediated angiogenesis
  JOURNAL   Cardiovasc Res 113 (14), 1776-1788 (2017)
   PUBMED   29016873
  REMARK    GeneRIF: demonstrate a functional relevance for cingulin-like 1 as
            a defining factor in new vessel formation both in vitro and in vivo
REFERENCE   6  (bases 1 to 7189)
  AUTHORS   Guillemot,L., Schneider,Y., Brun,P., Castagliuolo,I., Pizzuti,D.,
            Martines,D., Jond,L., Bongiovanni,M. and Citi,S.
  TITLE     Cingulin is dispensable for epithelial barrier function and tight
            junction structure, and plays a role in the control of claudin-2
            expression and response to duodenal mucosa injury
  JOURNAL   J Cell Sci 125 (Pt 21), 5005-5014 (2012)
   PUBMED   22946046
REFERENCE   7  (bases 1 to 7189)
  AUTHORS   Citi,S., Pulimeno,P. and Paschoud,S.
  TITLE     Cingulin, paracingulin, and PLEKHA7: signaling and cytoskeletal
            adaptors at the apical junctional complex
  JOURNAL   Ann N Y Acad Sci 1257, 125-132 (2012)
   PUBMED   22671598
  REMARK    Review article
            Erratum:[Ann N Y Acad Sci. 2012 Jul;1261:107]
REFERENCE   8  (bases 1 to 7189)
  AUTHORS   Narumiya,H., Hidaka,K., Shirai,M., Terami,H., Aburatani,H. and
            Morisaki,T.
  TITLE     Endocardiogenesis in embryoid bodies: novel markers identified by
            gene expression profiling
  JOURNAL   Biochem Biophys Res Commun 357 (4), 896-902 (2007)
   PUBMED   17462595
REFERENCE   9  (bases 1 to 7189)
  AUTHORS   Ohnishi,H., Nakahara,T., Furuse,K., Sasaki,H., Tsukita,S. and
            Furuse,M.
  TITLE     JACOP, a novel plaque protein localizing at the apical junctional
            complex with sequence similarity to cingulin
  JOURNAL   J Biol Chem 279 (44), 46014-46022 (2004)
   PUBMED   15292197
  REMARK    GeneRIF: JACOP is involved in anchoring the apical junctional
            complex, especially TJs, to actin-based cytoskeletons.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC093483.6 and AC107662.9.
            
            On Jun 7, 2022 this sequence version replaced NM_001304362.1.
            
            Summary: This gene encodes a protein localized to the tight
            junctions and adherens junctions in vertebrate epithelial cells.
            The encoded protein regulates the activity of Rho family GTPases
            during junction assembly and at confluence. At the adherens
            junctions, the encoded protein is part of a protein complex that
            links E-cadherin to the microtubule cytoskeleton. Alternative
            splicing of this gene results in multiple transcript variants.
            [provided by RefSeq, Jan 2015].
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB186125.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-527               AC093483.6         157672-158198       c
            528-2132            AC107662.9         197611-199215       c
            2133-2227           AC107662.9         196667-196761       c
            2228-2333           AC107662.9         194729-194834       c
            2334-2435           AC107662.9         190529-190630       c
            2436-2584           AC107662.9         189541-189689       c
            2585-2720           AC107662.9         188456-188591       c
            2721-2933           AC107662.9         178281-178493       c
            2934-3140           AC107662.9         129179-129385       c
            3141-3245           AC107662.9         128426-128530       c
            3246-3398           AC107662.9         124367-124519       c
            3399-3569           AC107662.9         123355-123525       c
            3570-3731           AC107662.9         118625-118786       c
            3732-3821           AC107662.9         114492-114581       c
            3822-3905           AC107662.9         105731-105814       c
            3906-4030           AC107662.9         104864-104988       c
            4031-4139           AC107662.9         103995-104103       c
            4140-4303           AC107662.9         103609-103772       c
            4304-7189           AC107662.9         99640-102525        c
FEATURES             Location/Qualifiers
     source          1..7189
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 39.85 cM"
     gene            1..7189
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /note="cingulin-like 1"
                     /db_xref="GeneID:68178"
                     /db_xref="MGI:MGI:1915428"
     exon            1..527
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            528..2132
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2227
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2333
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2334..2435
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2436..2584
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2585..2720
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2933
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            2934..3140
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3245
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3398
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3399..3569
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3570..3731
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3732..3821
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3822..3905
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            3906..4030
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            4031..4139
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            4140..4303
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     exon            4304..7189
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7167..7172
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /note="hexamer: AATAAA"
     polyA_site      7189
                     /gene="Cgnl1"
                     /gene_synonym="4933421H10Rik; 9930020M10Rik; Jacop"
                     /note="major polyA site"
ORIGIN      
        1 ggcccggctc tgcgggcagc tgccggagcg ggaccctgga ggcagaggcg gtaagtgagc
       61 tccgagcggg agcccggagg gtgtgcgcgg gaccccggag cccagacggt gcccgggaac
      121 tcgacaggct cgagctcctg cagctttgcg cagtgctcag cctcagcgtc ggtcgtggga
      181 tccgggcgcc gcggctgcag tcccggggct ggaggtgcgc tcctgcctcc tacgctgagc
      241 ccagtactgc agacgagtcg gacagttggt ggcgagcctg tacagggctc tagtgacagc
      301 tgcgggcgag ccccacggag caccgcactc ccaacccttc cctgcagtgt ttgatctcag
      361 tgctctttaa gccattcctt agaacaggct ggtggccgct ccgctgtcct ggccccgcgt
      421 gccactgcac tgtccaggca ggtcaccccg aaagccctta aaccacgaga gcactttttt
      481 cgctttctga gggacttttc caagttgcat caccgtttgg cttcaagctg ggacagagaa
      541 ccatggagct gtattttggc gaataccaac acgtacagca ggagtacggg gtacacctga
      601 gacttgccag tggtgacact ccaaagccaa ggaattccca gccctcaaag gcaggctcct
      661 atggtgtcag catcagggtc cagggaattg atggccaccc ttatatagtc ctgaataaca
      721 ctgagcggtg tctagcaggc acacctttcc cagaaaacgc gccatcgttt ccatcttcag
      781 tgataaataa cctgtcccta catccaagca atggaaccgt gttgaaggag aacactccgg
      841 aggaactgca gcttccagaa aacccgtacc tgcaaaccag cccgctaaga ggccagaagc
      901 agttctccct ccacgagggc aggaatggag ttctagaacg caaagacggg cccacgaagc
      961 tgccccatgt gctcaacttc cagaggcacc cggagcttct gcagccctat gacccagaaa
     1021 agaatgaggt gaacgcaaag aagcatcacc ctcccgagag tccctggctg agaaatgcaa
     1081 cagaggacgg gaccaactgt aagaagtccc ggaactgctt ccccaaatcc tacggttccc
     1141 agcccaacag ccctacttcg gaagatttag ccaagaccaa catgacagcg atccgtctct
     1201 gcagctctgt ggtcatagaa gacccccaaa agcagacctc agtgtgcgtg aacgttcaga
     1261 ggtgcgccaa ggagggggtg ggagaggaga ccctttcccc tcgacggaaa tccccaactg
     1321 cccccagccc acaggcctat tctgaaacca agaaaaacag gccagatgtg ctacccttcc
     1381 ggcgacaaga ttccgcagga cccatcctgg atggagctcg gtcacgcagg tcctcttcgt
     1441 catccacgac tcctacttct gccacttcct tgtacaaatt tttacttgat gatcaggaat
     1501 gcgccattca tgccgacagc gtcaaccgcc atgaaaacag aaggtatatt cccttcttgc
     1561 caggaactgg gcgggatatc gacacctgct caattcctgg tgtggaccag ttaattgaaa
     1621 aatttgacca aaagcctggc cttcagagaa gaggaaggtc tgggaagaga aacaggatca
     1681 atcccgacga caggaaaaga tcccgaagtg tagatagtgc ctttccattt ggtctccagg
     1741 gaaacacaga atacctcacc gagttcagca ggaacctggg caagtctagc gaacacctcc
     1801 ttcggccatc ccaggtcttc ccgcagaggt cagtggccca ggagcaccgt gggaagcaca
     1861 gtcccagcag cccgcccgca aagctgcagg gcgctcaagg tgcccacccc aagcctcccc
     1921 tgcagaacaa agatgggaaa gttctgaaca aaggaaggca ggaaagcacg ggggcatgtg
     1981 ccccctccct gccagcaccg aataaaaaag aggaagaaat caaaatagcc actgccacgt
     2041 tgatgttaca gaaccgggcg gtggctgcca catcggattc tggtgccaag aaaatttcag
     2101 tgaagacatt tccttccgac tccagcactc aggccacacc agatctctta aagggccagc
     2161 aggagctcac acaacaaacg aacgaggaga ccgccaagca gatcctttac aattacctca
     2221 aagaaggagg cacagacaat gaggatgcca ccaaaaggaa agtgaacctg gtctttgaga
     2281 aaatccagac tttgaagtcc agagcagcag ggagtgccca aggaagcaat caagctccga
     2341 attctccctc tgaaggcaac agtctattgg atcagaagaa caaattgatc ctagaagtgt
     2401 ctgaactaca gcagcaactg caactggaga tgaagaacca acagaacatc aaggaggagc
     2461 gagaaagaat gagagaggat ttagaagagc tgcgagtccg gcaccagagc caagtggagg
     2521 agacggccac cctgcagaga cggctggagg aaagtgaagg cgagctgagg aagagcttgg
     2581 aagagctgtt ccaagtgaag atggagcgtg aacagcacca gactgagatc agagacctgc
     2641 aggaccagct gtcggaaatg catgatgagc tagacagcac caagcgatcc gaggacaggg
     2701 agaagggagc cctgattgag gagctcctgc aagccaagca ggaccttcaa gatctgctca
     2761 ttgccaaaga ggaacaggaa gatctcttga ggaagcggga gcgggagctg actgccttga
     2821 agggcgcctt gaaggaggag gtttccagcc atgaccagga gatggataag ctgaaggaac
     2881 agtacgatgc tgagctgcag gccctcaggg agagtgtgga ggaggcaacc aagaatgttg
     2941 aggtcctggc cagcaggagc aactcctcag agcagagcca ggcggaggct gacctgcgtg
     3001 agaaagtgct gaaggaggag aatgagaagc tgcaggggag gattgcggag ctggagcgca
     3061 gggcagccca gctacagagg cagatggagg atgtgaaggg tgacgaggcc caagcaaagg
     3121 agacactccg aaagtgtgag agtgaagtac agcagctgga ggaagccctt gtgcatgcca
     3181 gaaaggaaga aaaagaagcc acatgtgcca gaagggcgct ggagaaggag ctggagcaag
     3241 ctcggagaga gctgagccag gtctcccagg agcagaagga actcctggag aaactccggg
     3301 acgaggcgga gcagaaggag cagctgcgaa agctgaagaa cgagatggag agcgagcggt
     3361 ggcacctgga caagaccatc gagaagctgc agaaggagat ggccgacatt gctgaggcct
     3421 cccgcacatc ctctttggag ctgcagaagc agctgggcga gtataaggag aagaaccgcc
     3481 gggagcttgc ggaaatgcag acacaactga aggagaaatg cctggaagtg gaaaaggcca
     3541 gactggcagc ctcgaagatg caggatgagt tacgcctcaa ggaggaagag ttgcaggact
     3601 accagcgagc tgaggaggag gcgctcacaa aacggcagct tctggagcag tcgctgaagg
     3661 acctggagta tgagctggag gccaagagcc acctcaagga tgaccgcagc cgactcatca
     3721 agcagatgga ggacaaggtg tcccaattgg agattgaatt ggaagaagaa agaaccaacg
     3781 ctgacttgct gtcggagagg atcacgtgga gcagggaaca gatggagcag atgaggagcg
     3841 agcttcttca ggagaaagct gccaagcaag acttagagtg tgacaagatt tccctagaga
     3901 gacagaacaa agacttaaag agccggatta tccacctgga aggttcctac aggtccagca
     3961 aggagggcct ggtggtgcag atggaggcca ggattgcaga gctggaggac cggctggaga
     4021 atgaggagag ggatcgggcc aacctgcagc tcagcaaccg aaggctggag cggaaggtga
     4081 aggagctggt gatgcaggtg gatgatgagc atctgtcact gacggaccag aaggaccagc
     4141 tgagcttgcg cctgaaagcc atgaagcgcc aggtggagga ggctgaagag gagatcgacc
     4201 gactggaaag ttctaagaag aagctgcaga gggagctgga ggagcagatg ggggtgaatg
     4261 agcagctgca ggggcagctc aactctctga agaagggctt aaggcttaag acactgtcta
     4321 gtaaagtact ggacgactcg gacgacgacg acctcagcag tgatgcggga agcctctacg
     4381 aagccccact gagctatgcc tttcccaaag acagcactat cgccagccag atctgagtct
     4441 gcttccaggc ccgttgatcc tgacaggact ctgcagtcat ctagacagag taggaggcac
     4501 taaatagagc ttgtgaatgg agtcagaccc acggttacca cctcacattc ctcctggggc
     4561 ctctgcgtgg ttgagtgacc ttggatctta gatagggagc tattgaagtt tcagatgacc
     4621 taactgggac atttgggggt aagacaaagc cccattgtgc actgctgtct gccatcactc
     4681 cttctcctgc cccggagaag gttccagtgc cagctgtaat gatataggga cacataggga
     4741 tgaaatgatg tatagactga accagacctt ctcaaggacc gctgttctcc ttaaggatgc
     4801 tccagagcct ttcgagtatg acatctttgt aaagttcaca aactgatctt gattatcttt
     4861 taaaatatga agctaccaga tctcaagtat taagaagctg gaggcaaagg agggagagtg
     4921 aaggctattc tggaaaccag agggggtcag acagtgggaa tcaataattg gtttgtatgg
     4981 gaaaccagct cattgatggt tggggaagga cacttaggcg gagtctgagg ccttggttgc
     5041 ttattttatc tgaaccatgc aaagagcagt ccctactccc cactgctttc aagcaagcag
     5101 aatgggagac agatgagatt tttaacaagt gctgtgcttc ctaaaggaca agagcgctgt
     5161 tgttgtgtct ccttggccct tttcctccat ggcagacctc caagcgaagc tcgctcaggc
     5221 ctggaattgg aggaatagga ggggccttga gacgaggcct atgggcttag gtatgaggct
     5281 aaggagggag gcatccagga agttcatggg gcaggggatg agtaagtggg tatggggctg
     5341 atgtaagaag gaatacagag acgttcttga aagctggggg atgtgcaaga agggcagggg
     5401 gtgggggttg agctggagtt tggaatgatg ggaaaaggga ttgggagtgc ttgccatctg
     5461 aagggctgtt tttgggaaca ggtgtcagga aggggtgagg tccaagggca agcacatgat
     5521 gccaaggtag ttttgggagg atgctgggca tccctgcata tctcctggcc tacccatgtc
     5581 tcctcatgac tgtgacagtc acctatgaaa gagccttgtg agttgcctat gtgtaaggca
     5641 gaggtgacag gacactggag cagagtcctc aggcttcctg atatggggac tcctggggac
     5701 caggttacca taaggtcctg tccacagcag gtcagagttc acacagctag attcagagaa
     5761 gggatctgaa ggatgagcat ctgctgccag agaaccaagc cctattacac atcccgagat
     5821 ccactgtctc cctcgcctgt ctcctcactg ggtatggaga gacttctgct ttcagccatt
     5881 cttccatgta acaagcatgt actatcatcc atcaaaatgt gtcaggcaca gacttgggca
     5941 ctggaaacac agtaaataga agtaaaaatg ttgagccgga aatgtagctc agctggggca
     6001 atgcgtgcct agcgtgcagg aagccctgta tttaaccccc aactctataa accgggtgtg
     6061 gtgtggtatg cctgtgatcc caacacagga agtggcaaca ggaggatcca gagttcaaag
     6121 tcagccttgg atacatatgc aggtcttggc caagctgggt tatataggag gccccgtctc
     6181 aaaaaaaccc aaccaaccct gccctcctgt aaccatccag gagagtgtga tgcagcctga
     6241 acctctctat actcagcctc ggagaacctc tgtcctcttg ggaatgtgat ggcctgcgat
     6301 tggttggctg gttccccaga acacacagga attctttagc tcctagaatc ttctcatgtc
     6361 atcattcgat atttgtactc agcctagaaa tgtctcagcc tgctcatccc agagattcag
     6421 gtgacaaaaa tcaagacccc gaggaagggt gtttgttttg tggtttgaca aaaattagcc
     6481 agcccttatt ccagtcagtt ccttctggta gccatggggc taactatatg aaggaagata
     6541 gctcgtggaa gggagagcag aggccaccac tggaaacact tgtagagtcc ctcaccccac
     6601 cacacacaca cacaccagag gaggctaaac gagatgaggg catgtctcct gtgctgtaat
     6661 ggagtgggca gcgagccggt gtgtgcagta tagtcagtga gtgacgcgac actggaatga
     6721 ggtttagaac gaggtttgta agtcccagcc tcatctcttc cctgtgatcc tgacaggtgc
     6781 atcctgggac aaggtggcga ttaggactcc aggtccttct cagctcgaat ctgttgagca
     6841 tcccttggtc ttcttatata tacatgtttt tctgtttatt cctttaagaa ctaatcctgc
     6901 tcaagagcgt tttctttagc tagcttaaaa atatctcctg taaaaacata catgttgcca
     6961 agtgcaatgt tgagaagaca atcactgtat ggcttttata aatttgtttt tcctgctctg
     7021 gagtgtcatt ccaccatgac agttggaata ttctggtggg tcttttagta gggattggtt
     7081 actatgcgtt gtcatgggga agagacattt tttatcacag ctacctccat gggaatgact
     7141 tcatggataa agcaaggttt cctttcaata aactgtcact tgacaggaa
//
