LOCUS       NM_207653               6913 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus CASP8 and FADD-like apoptosis regulator (Cflar),
            transcript variant 1, mRNA.
ACCESSION   NM_207653
VERSION     NM_207653.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6913)
  AUTHORS   Hong,M., Wu,X., He,P., Peng,R., Li,L., Wu,S.Q., Zhao,J., Han,A.,
            Zhang,Y., Han,J. and Yang,Z.H.
  TITLE     Residue Y362 is crucial for FLIPL to impart catalytic activity to
            pro-caspase-8 to suppress necroptosis
  JOURNAL   Cell Rep 43 (11), 114966 (2024)
   PUBMED   39520684
REFERENCE   2  (bases 1 to 6913)
  AUTHORS   Ye,C., Jiang,W., Hu,T., Liang,J. and Chen,Y.
  TITLE     The Regulatory Impact of CFLAR Methylation Modification on Liver
            Lipid Metabolism
  JOURNAL   Int J Mol Sci 25 (14), 7897 (2024)
   PUBMED   39063139
  REMARK    GeneRIF: The Regulatory Impact of CFLAR Methylation Modification on
            Liver Lipid Metabolism.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6913)
  AUTHORS   Yang,X., Zeng,Q., Inam,M.G., Inam,O., Lin,C.S. and Tezel,G.
  TITLE     cFLIP in the molecular regulation of astroglia-driven
            neuroinflammation in experimental glaucoma
  JOURNAL   J Neuroinflammation 21 (1), 145 (2024)
   PUBMED   38824526
  REMARK    GeneRIF: cFLIP in the molecular regulation of astroglia-driven
            neuroinflammation in experimental glaucoma.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6913)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 6913)
  AUTHORS   Tsuchiya,Y., Seki,T., Kobayashi,K., Komazawa-Sakon,S., Shichino,S.,
            Nishina,T., Fukuhara,K., Ikejima,K., Nagai,H., Igarashi,Y.,
            Ueha,S., Oikawa,A., Tsurusaki,S., Yamazaki,S., Nishiyama,C.,
            Mikami,T., Yagita,H., Okumura,K., Kido,T., Miyajima,A.,
            Matsushima,K., Imasaka,M., Araki,K., Imamura,T., Ohmuraya,M.,
            Tanaka,M. and Nakano,H.
  TITLE     Fibroblast growth factor 18 stimulates the proliferation of hepatic
            stellate cells, thereby inducing liver fibrosis
  JOURNAL   Nat Commun 14 (1), 6304 (2023)
   PUBMED   37813881
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6913)
  AUTHORS   Yeh,W.C., Itie,A., Elia,A.J., Ng,M., Shu,H.B., Wakeham,A.,
            Mirtsos,C., Suzuki,N., Bonnard,M., Goeddel,D.V. and Mak,T.W.
  TITLE     Requirement for Casper (c-FLIP) in regulation of death
            receptor-induced apoptosis and embryonic development
  JOURNAL   Immunity 12 (6), 633-642 (2000)
   PUBMED   10894163
REFERENCE   7  (bases 1 to 6913)
  AUTHORS   Wang,J., Lobito,A.A., Shen,F., Hornung,F., Winoto,A. and
            Lenardo,M.J.
  TITLE     Inhibition of Fas-mediated apoptosis by the B cell antigen receptor
            through c-FLIP
  JOURNAL   Eur J Immunol 30 (1), 155-163 (2000)
   PUBMED   10602037
REFERENCE   8  (bases 1 to 6913)
  AUTHORS   Varfolomeev,E.E., Schuchmann,M., Luria,V., Chiannilkulchai,N.,
            Beckmann,J.S., Mett,I.L., Rebrikov,D., Brodianski,V.M.,
            Kemper,O.C., Kollet,O., Lapidot,T., Soffer,D., Sobe,T.,
            Avraham,K.B., Goncharov,T., Holtmann,H., Lonai,P. and Wallach,D.
  TITLE     Targeted disruption of the mouse Caspase 8 gene ablates cell death
            induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal
            prenatally
  JOURNAL   Immunity 9 (2), 267-276 (1998)
   PUBMED   9729047
REFERENCE   9  (bases 1 to 6913)
  AUTHORS   Goltsev,Y.V., Kovalenko,A.V., Arnold,E., Varfolomeev,E.E.,
            Brodianskii,V.M. and Wallach,D.
  TITLE     CASH, a novel caspase homologue with death effector domains
  JOURNAL   J Biol Chem 272 (32), 19641-19644 (1997)
   PUBMED   9289491
REFERENCE   10 (bases 1 to 6913)
  AUTHORS   Irmler,M., Thome,M., Hahne,M., Schneider,P., Hofmann,K.,
            Steiner,V., Bodmer,J.L., Schroter,M., Burns,K., Mattmann,C.,
            Rimoldi,D., French,L.E. and Tschopp,J.
  TITLE     Inhibition of death receptor signals by cellular FLIP
  JOURNAL   Nature 388 (6638), 190-195 (1997)
   PUBMED   9217161
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112968.11.
            
            On Sep 20, 2017 this sequence version replaced NM_207653.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927932.3785413.1, BC029223.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-374               AC112968.11        86457-86830
            375-801             AC112968.11        99477-99903
            802-907             AC112968.11        102227-102332
            908-1043            AC112968.11        104323-104458
            1044-1117           AC112968.11        105424-105497
            1118-1172           AC112968.11        108829-108883
            1173-1222           AC112968.11        113434-113483
            1223-1304           AC112968.11        114136-114217
            1305-1812           AC112968.11        125510-126017
            1813-6913           AC112968.11        126955-132055
FEATURES             Location/Qualifiers
     source          1..6913
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 29.16 cM"
     gene            1..6913
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /note="CASP8 and FADD-like apoptosis regulator"
                     /db_xref="GeneID:12633"
                     /db_xref="MGI:MGI:1336166"
     exon            1..374
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            375..801
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            802..907
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1043
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1117
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1172
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1222
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1304
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1812
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..6913
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6891..6896
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /note="hexamer: ATTAAA"
     polyA_site      6913
                     /gene="Cflar"
                     /gene_synonym="2310024N18Rik; A430105C05Rik; c-Flip; Cash;
                     Casper; CLARP; FLAME; FLAME-1; Flip; Gm9845; I-FLICE;
                     MRIT"
                     /note="major polyA site"
ORIGIN      
        1 ctcttgttag gattgtggaa ttcagcaatg gcctcgattc agttttggtg aaatggcggc
       61 cattctcatc ttctcggagc ccttctcttt gctcacactc gcgattctgc ccccgcaaga
      121 gtactctggg gacgtcctta tcgctgggag agagcggtcg catctcattc ctgaacctgt
      181 tgggctcgct gggcgcgtca cctggctagc agcttgggcc agctccgcag gctaactttc
      241 ctggacgcct actgaagagt ctgctcctct ctgtgttctt tccagtgtct cgttcgatcc
      301 agttttctgg tggtctccag cgaagacagg cgacaaagcc gttgttgagt gggatgggcc
      361 ggcgaccgcc cggtagtgtc tctattgcaa gaactctgag agaaatgaag agagtcctca
      421 gcaatgatgt tggcttctcg tggttcccag agccctgctt aatggatgga gactggacga
      481 gaacctggct gctgtggttc tgaacatggc ccagagccct gtgtctgccg aggtcattca
      541 ccaggtggaa gagtgtcttg atgaagacga gaaggagatg atgctcttcc tgtgtagaga
      601 tgtgactgag aacctggctg cacctaacgt cagggacctc ctggatagct taagtgagag
      661 aggccagctc tcttttgcta ccttggctga attgctctac agagtgaggc ggtttgacct
      721 tctcaagagg atcttgaaga cagacaaagc aaccgtggag gaccacctgc gcagaaaccc
      781 tcacctggtt tctgattata gggtcctgct gatggagatt ggtgagagct tagatcagaa
      841 cgatgtatcc tccttagttt tccttacaag ggattacaca ggcagaggca agatagccaa
      901 ggacaagagt ttcttggatc tggtgattga attggagaaa ctgaatctaa ttgcttcaga
      961 ccaattgaat ttgttagaaa aatgcctgaa gaacatccac agaatagact tgaacacaaa
     1021 gatccagaag tacacccagt ccagccaagg agcaagatca aatatgaata ctctccaggc
     1081 ttcgctccca aaattgagta tcaagtataa ctcaaggctc cagaatgggc gaagtaaaga
     1141 gccaagattt gtggaatacc gtgacagtca aagaacactg gtgaagacat ccatccagga
     1201 atcaggagct tttttacctc cgcacatccg tgaagagact tacaggatgc agagcaagcc
     1261 cctaggaatc tgcttgatca ttgattgtat tggcaacgac acaaaatatc ttcaagagac
     1321 cttcacttcc ctgggctatc atatccagct tttcttgttt cccaagtcac atgacataac
     1381 ccagattgtt cgccgatatg caagtatggc ccaacatcaa gactatgaca gctttgcatg
     1441 tgttctggtg agcctaggag gctcccaaag catgatgggc agagatcaag ttcactcagg
     1501 gttctccttg gatcatgtca agaacatgtt cacgggggac acgtgccctt ctctcagagg
     1561 gaagccaaag ctctttttta ttcagaacta tgagtcgtta ggtagccagt tggaagatag
     1621 cagcctggag gtagatgggc catcaataaa aaatgtggac tctaagcccc tgcaacccag
     1681 acactgcaca actcacccag aagctgatat cttttggagc ctgtgcacag cagacgtatc
     1741 tcacttggag aagccctcca gctcatcctc tgtgtatctg cagaagctct cccagcagct
     1801 gaagcaaggc aggagacgcc cactcgtgga cctccacgtt gaactcatgg acaaagtgta
     1861 tgcgtggaac agtggtgttt cgtctaagga gaaatacagc ctcagcctgc agcacactct
     1921 gaggaagaaa ctcatcctgg ctcctacgtg agaaccccag accgttggtg ttcttggtat
     1981 atcatccagg gtggcggctt ggagcagagc ttggcggtta cggctgcttc tggctgcttc
     2041 tggctctgcc gtgagtcctg gcctagggtt ctcctgtgca caggcatgag ccgtaaccct
     2101 gtgcctggga aacgtctcac tcccgccgcc gtgcctttac ctctctaaac ttccctactt
     2161 acattcctta gtcggatgtt ttgccagagt gtggagaaca gtaagacata aacctattgt
     2221 ttgtttgttt ttttgggggg gaggttatct accaagttat accaagttat tgtatgggtg
     2281 tatagtgtat agtggttcaa gatttgacac tgaatgtaac ttgagactta cctgagtttg
     2341 tcatgcgact gggtaaattg tttctatggc acatctaatc atttaataag taattacctc
     2401 attaagtacc cattgcttca ggactttcac attggccacc aatttctgtg acccagctcc
     2461 acatttatat tctctttctg caaaaccaaa tttcattatg tctgtttaat atctacagtc
     2521 taatgctttg taagacatct agatagaaaa atagttaccc atgagcacag gagggctggc
     2581 ctgaccctca ccagctgtgc agtggcttcg gtgaaggaga atgagcccta ctccttgaag
     2641 gttgtagtgc ttgggagagc agtctgtacc ttgcctgggc agcacagtag agccagcccc
     2701 aagaacacaa cagtgagtgg gggagcttgc cctggttggc tcaggatcag gaacaggagg
     2761 gatgaccaac ttggggcttt gaggtggccc accccagcat ccatatcatc tgtgaactgc
     2821 cagagcctgt gaaggggcgg gtcctgtaga actaaggctg caggatctcc atgacacagg
     2881 gcaacaacag ggtatctgag aagggtcccc gtgagggtcc agtatttata gtgcaccaga
     2941 agccagaggc ctcggatcag acaatgaccc attgcactga gtaaagatgt aagtgaatga
     3001 gtgaagatgt gtgggcacac ggaaatactg agggacacac acaagctttt atggagatgt
     3061 ttgtttgttt gtttgtttgt tttttgtttc tttggcagga acagattgca agggcagaga
     3121 gtagataagg aagctggaga catgagtggg gttgggtgca tgatatagaa ttcacaaaga
     3181 atcaaaaaaa aaaacttaaa aaaatggttg cctagtgaga ttacttattt ataatttata
     3241 tagctagctt tttttgtaac aagagcaaat agaatttatt tatttattaa atacatttga
     3301 agcaaggttg taacgtacgt agcaaaactc ctgccatacc agtactagcg tgggggaggc
     3361 caaaggatca catgttctga accagtctag gtatgtagta gctgtgtaat gagattgtgt
     3421 gtttgcctgc ttgtgagaga gaggagagag ataaattcca aaacatgtaa catggtataa
     3481 ttttattagc tgctataaaa catggttatt ttactttgta tactcttgag taacctaata
     3541 gtataatcta tctgtatttg aggatagtag tcaaacccct cccctcaggg tttagggacc
     3601 tgttctgaag aggaggcaga aagactgtga gagccagagg tggtgaaggg ctccagggaa
     3661 gccgcatctt ccagacagaa caggacccgt gcacatgtgg ctgacagcac aggttcaaac
     3721 cagacagagt cccaacactg agaaagggag acgaagttgt gggccattgt gctcacacct
     3781 gagcacagtg ggaatcagga gtgttcaacc ctcagggttg tctcgtcaga gggagagatg
     3841 tataacctgt ttctgcccag aaggcaggaa caatgtgatt cgtagctggt ggtctctgca
     3901 ctatttgtac caccaagcca caccgcctcc ctcagactca agttcatgtc agtcaatcgg
     3961 cagtctgccc tccctgccaa cctcatcagg accactgttt tccctgagcc tgcttcctca
     4021 gttaattcag agaacctatc tgtatgcaag atgttgcttg tactctacaa gagtttcagt
     4081 atagccatct cctaagcttt tctgtacaca caggactgat taattatcac cagaaactat
     4141 tttgaaattg tgctgtgcct aaaataaact acttggtgct agactccaga agtttggaca
     4201 aaaactgtcc actgagtcac gttgagacag actttcttct tgcttctctt ggatcaacac
     4261 cctgctggtt aaggtgtttg cagagatccc cacgaagggg aggttgtgca gtagatagct
     4321 gctgagaaag ggaagtcagc tttctccagt ggagtgttat tggacatatc cattacccgt
     4381 cagggcaggc cccagaccca ggagtaattg gctaacataa aatggactct gtgtgcttgt
     4441 ctttttattg attttctttc tttctttctt tctttctttc tttctttctt tctttctttc
     4501 tttctttctt tctttccttc cttccttcct tccttccttc cttccttcct tgttttgttt
     4561 tgtttttgtt tttttgagac agggtttctc tgtatagccc tggctgtcct ggaactcact
     4621 ttgtagacca ggctgacctc gaactaactc tctctctctc tctctctctc tcgtttgttt
     4681 gctttgctgt tcaagttttt tcgttttttg agagagagag agggagcgca agagaacatg
     4741 aagttatatg agtgggggtg ggtgaaatgg ggaggatagg gaagagcagg gagggaaaaa
     4801 gagcatccca cgggactgtt tcaaggacca agtgtgaggg gctttacaac catttttgag
     4861 ctgtgctctt aattagttat atcattaatt gtatcattag accacagtgt aacggggctg
     4921 ttttggaagg actgagtcaa actttgaaaa gctgatggga cttggcaggt ggtgatagag
     4981 aagagagcgt aagtcaaggg aaggagccaa cgggagctgc acagtgagct ttagagacct
     5041 caagagtgac ttttagctgg ggcagatgtg cacagtgatg gtgtcagtga tggatggtgt
     5101 caggaggtgg atgtggtcct ggtgtggaga aggccccact tttttccctt agctagttgt
     5161 ctagtaagat atttctcggg gctggtgaga tggctcagtg ggtaagagca cccgactgct
     5221 cttccaaagg tccagagttc aaatcccagc aaccacatgg tggctcacaa ccatctgtaa
     5281 caagatctga ctccctcttc tggagtgtct gaagacagct acagtgtact tacatataat
     5341 aataaataag tctttaaaaa aaaaaagata tttctcctta ctttcatagt aggatctttg
     5401 gttacttctt tgttcctttt gtagacagaa ttgagatttt tgtttttcac cgactttggg
     5461 gttttttctg aaatatttta gacatattaa aagataatta tgtatggaag acaatgaata
     5521 cctgttttaa ataaaatgtt ctaaacttgt atgtgaatac tcataatata gttctttaag
     5581 gcactgatct ttaagtgata tataccctaa aatatttcaa actaatagtt agccaagcat
     5641 atggttaagt ttatagttat gatgggctac caagagattc tgtcactatt aacattttat
     5701 gtataaataa gaacatatat taattaacag gcatttaaac acttggtctc caggtgtgct
     5761 gtttgaaagg tgtggcctcg ctagaggaac tgttactggg ggacagggac aggctttgag
     5821 gtttcaaagg cttataccat ttccagtttg ctctgtattt attgaatata ctattgtata
     5881 atgtatatca tattgtatat attgtaatat atataaaaat atttattgga ggtaaaatga
     5941 gaaaactgag aagcatgtat tccacatgtg tgctctgtgg aggacatttc atattcagat
     6001 tgtaaccgta gatgttatgg ctggagttct aactctcaca gctatggaga taatatacag
     6061 taggaggtag ctgagtggtg aacaagagac agaatcagcc aggcatggca gttcctacag
     6121 aggcaggagg attgccacaa gtttgaggcc agactgtgtc atgctccatc cctggtgaaa
     6181 agggagcaga attaacaaac tgccccagat tacccttgga catgaaggga aataacggga
     6241 tttaggggca gcaagatggc tcgctcagtg gtaaaggtgt ttcctgccag gtctgaacac
     6301 tgaatcccca ggaaggagtg ctccagcgtc agaaagctgt ccaccgatct ccgcaagggt
     6361 gcacgaccca tgcacacacc cacccacaca cacacagaga aaacattgcc aggatgaggg
     6421 tcattttaga cactgtaata gtttgcatat tgcacatctg tgatgctttg agttaatttt
     6481 gttaaaagct aagattcgtt tgcagatttt tttcatgatt tttggcttgt tctgcatcat
     6541 gtactgaaag agcattttcc agtgaattgc tttgatgctt ttcagaggtc agtgggttgt
     6601 gtttgcaggg cctatttgtg aacttaattg tattctgttg attcactgat gtgttatttc
     6661 agaatcatac catctcggtt gccatagctt acattaagcc ctgatgtaaa cgatgctggg
     6721 ggaatagaga gttctgctgg aatatgtttt cttttttgtt ctgtgggggg gtcttttttt
     6781 ttgttttagg gtctcactat gtaactcacg tgtgggattt atcttctgcc tctgtctgct
     6841 tgctgagatt ctaggcataa ttgctctgtt tcattttaag gagtcattac attaaagatt
     6901 atttctttta aaa
//
