LOCUS       NM_001029977            2887 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus complement factor H-related 4 (Cfhr4), transcript
            variant 1, mRNA.
ACCESSION   NM_001029977 XM_001006007
VERSION     NM_001029977.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2887)
  AUTHORS   Hellwage J, Eberle F, Babuke T, Seeberger H, Richter H, Kunert A,
            Hartl A, Zipfel PF, Jokiranta TS and Jozsi M.
  TITLE     Two factor H-related proteins from the mouse: expression analysis
            and functional characterization
  JOURNAL   Immunogenetics 58 (11), 883-893 (2006)
   PUBMED   17028856
REFERENCE   2  (bases 1 to 2887)
  AUTHORS   Vik DP, Munoz-Canoves P, Kozono H, Martin LG, Tack BF and Chaplin
            DD.
  TITLE     Identification and sequence analysis of four complement factor
            H-related transcripts in mouse liver
  JOURNAL   J Biol Chem 265 (6), 3193-3201 (1990)
   PUBMED   1689298
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC115748.8, BC145444.1 and AJ871401.1.
            
            On May 19, 2009 this sequence version replaced NM_001029977.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ871401.1, ERR2680379.311477.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                AC115748.8         48409-48436         c
            29-1050             BC145444.1         1-1022
            1051-2700           AJ871401.1         980-2629
            2701-2887           BC145444.1         2670-2856
FEATURES             Location/Qualifiers
     source          1..2887
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 61.62 cM"
     gene            1..2887
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /note="complement factor H-related 4"
                     /db_xref="GeneID:214403"
                     /db_xref="MGI:MGI:3646434"
     exon            1..144
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..2711
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; complement factor H-related protein C"
                     /codon_start=1
                     /product="complement factor H-related protein C isoform 1
                     precursor"
                     /protein_id="NP_001025148.3"
                     /db_xref="CCDS:CCDS35730.1"
                     /db_xref="GeneID:214403"
                     /db_xref="MGI:MGI:3646434"
                     /translation="MGFCSMLLLSNILLTAWLSTAKGEVKSCEFPQFKYGRLYYEEIL
                     RPNFPVSIGNKYSYKCDNGFSPPSGIFWDYLRCTVQGWEPEVPCVRKCVFHYVENGQS
                     AYWEKIYVQGQSLKVQCYNGYSLQNGQDTMTCTENGWSPPPKCIRIKTCSVSDIEIEN
                     GFFSESFRTYALNRETSYRCKQGYVTNTGETSGSITCLQNGWSPQPSCIKSCERPVFE
                     NSVTKNNSTWFKLNDKLDYECLIGYENEYKHTKGSITCTYYGWSDTPSCYEIECSVPI
                     LDRKLVVSPRKEKYRVGDLLEFSCRSGHRVGPDSVQCYHFGWSPSFPTCKAGQVASCA
                     QPPEIPNGEINGAKRVEYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCVEEER
                     TCGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCLSGKWTQLPKCVAT
                     DQLEKCRVLKSTDIEAIKPKRKEFQHNSTMYYKCRDKQEYEHSICINGKWNPEPNCIR
                     KISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMCKDGRWQSLPHCI
                     EKIPCSQPPTIEHGSIKLPRTSEKRRKSIEFSSHEHGTTFSYVCDDGFRIPEENGVAC
                     YMGKWSTPPRCVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC
                     EGGKWSDPPKCIKTDCDILPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNGSDTVT
                     CINGRWIGKPVCKDSRGKCGPPPPIDNGDITSLSLPEYEPFSSVDYQCQKYYLLKGKK
                     TITCRNGKWSEPPTCLHACIIPENIMEARKIILKWRHTKNIYSHSGEDIEFECKYGYH
                     KARGSPPFRTKCISGTINYPICE"
     exon            145..339
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            340..516
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            517..699
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            700..876
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            877..1050
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1236
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1416
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1593
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1770
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1980
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2154
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            2155..2331
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..2514
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
     exon            2515..2887
                     /gene="Cfhr4"
                     /gene_synonym="Cfhrc; EG214403; Gm4788"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcatacaca gcattgttaa tgacagggtt cccagaagga ccaccacatc tggagcttta
       61 agcttgagaa catggggttc tgcagcatgt tgctcttatc caatatcctc ctaactgcat
      121 ggctttccac tgctaaaggg gaagtgaaat cttgtgaatt tccacaattc aaatatggac
      181 gtctgtatta tgaagagatc ctgagaccca acttcccagt atctatagga aataagtaca
      241 gctataagtg tgacaacggg ttttcaccac cttctgggat tttctgggac taccttcgtt
      301 gcacagtaca agggtgggag cctgaagtcc catgcgtcag gaaatgtgtt ttccattatg
      361 tggagaatgg acaatctgca tactgggaaa aaatatatgt gcagggtcag tctttaaaag
      421 tccagtgtta caatggctat agtcttcaaa atggtcaaga cacaatgaca tgtacagaga
      481 atggctggtc ccctcctccc aaatgcatcc gtatcaagac atgttcagta tcagatatag
      541 aaattgagaa tgggtttttt tctgaatctt ttcgtacata tgctctaaat agagaaacat
      601 cctatagatg taaacaggga tatgtgacaa atactggaga aacatcagga tcaataactt
      661 gccttcaaaa tggatggtca cctcaaccct catgcattaa gtcttgtgaa agaccagtat
      721 ttgagaattc tgtaactaag aataatagta catggtttaa gctcaatgac aaattagact
      781 atgaatgtct cattggatat gaaaatgaat ataaacatac caaaggctct ataacgtgta
      841 cttattatgg atggtctgat acgccctcat gttatgaaat agaatgcagc gttcccattc
      901 tagaccgaaa actagtcgtt tctcccagaa aagaaaaata cagagttgga gatttgttgg
      961 aattctcctg ccgttcagga cacagagttg ggccagattc agtgcaatgc taccactttg
     1021 gatggtctcc tagtttccct acatgtaaag caggtcaagt agcatcatgt gcacaacctc
     1081 ctgaaattcc taatggggaa attaatggag caaaaagagt tgaatacagc catggtgagg
     1141 tggtgggata tgattgcaaa cctagattcc tactgaaggg acccaataaa atccagtgtg
     1201 ttgatgggat gtggacaacc ttgcctgtat gtgttgagga ggagagaaca tgtggagaca
     1261 ttcctgaact tgaacatggc tctgtcaagt tttctgtccc tccctaccac catggagatt
     1321 cagtggagtt cacttgtgca gaaaccttca caatgattgg acttgggtca gttttttgcc
     1381 ttagtggaaa gtggacccag cttcctaaat gtgttgcaac agaccaactg gagaagtgta
     1441 gagtgctgaa gtcaactgac atagaagcaa ttaaaccaaa aagaaaagaa tttcagcata
     1501 actccaccat gtattacaaa tgtagagaca agcaggagta tgaacactcc atctgtatca
     1561 atggaaaatg gaatcctgaa ccaaactgta taaggaaaat atcctgccct cctccaccac
     1621 agattccaaa tacccaagtg attgaaacca ctgtgaaata cttggatgga gaaaaattat
     1681 ctgttctttg ccaagacaat tacctaactc aggacccaga agaaatgatg tgcaaagatg
     1741 gaaggtggca gtcattacct cactgcattg aaaaaatccc atgttcccag ccccctacaa
     1801 tagaacatgg atctattaaa ttacccagaa catctgaaaa aaggagaaaa tccattgagt
     1861 tcagcagtca tgaacatgga actacattca gctatgtctg tgatgatggt ttcaggatac
     1921 ctgaagaaaa tggggtagcc tgctacatgg gaaaatggag cactccacct cgctgtgttg
     1981 gacttccttg tggacctcca ccttcaattc ctcttggtac tgtttctctt gagctagaga
     2041 gttaccaaca tggggaagag gttacatacc attgttctac aggctttgga attgatggac
     2101 cagcacttat taaatgtgaa ggaggaaagt ggtctgaccc accaaaatgc ataaaaacgg
     2161 attgtgacat tttacccaca attgaaaatg ccataataag aggaaagaac aaaaaatcat
     2221 ataggacagg agaacaagtg acagtcagat gtcaatctcc ttatcaaatg aatggctcag
     2281 acactgtgac atgtattaat ggccggtgga ttggaaagcc agtatgcaaa gactcaagag
     2341 ggaaatgtgg gcctcctcca cctattgaca atggagacat cacctccttg tcattaccag
     2401 aatatgaacc attctcatca gttgactatc agtgccagaa gtattatctc cttaagggaa
     2461 agaagacaat aacatgtaga aatggaaagt ggtctgagcc accaacctgc ttacatgcat
     2521 gtataatacc agaaaacatt atggaagcac gcaaaataat tcttaaatgg agacacacta
     2581 aaaatattta ttcccattca ggggaggata ttgaatttga atgtaaatat ggatatcata
     2641 aagcaagagg atcaccgcca tttcgtacaa agtgcattag tggcaccatc aattatccca
     2701 tttgtgaata aaattgtaat acatttatta attgatttta ttgtttagaa atgcacaagc
     2761 atgtcactaa tatactttca atttgcattt gaaatattgt ttaactcatg tcttctcata
     2821 aatataaaca tttttttata tagtgattaa tttttaactt taaagatgat tgccaaaatg
     2881 caaatgc
//
