LOCUS       NM_001039495            5718 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cilia and flagella associated protein 65 (Cfap65),
            mRNA.
ACCESSION   NM_001039495
VERSION     NM_001039495.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5718)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5718)
  AUTHORS   Wang,W., Tian,S., Nie,H., Tu,C., Liu,C., Li,Y., Li,D., Yang,X.,
            Meng,L., Hu,T., Zhang,Q., Du,J., Fan,L., Lu,G., Lin,G., Zhang,F.
            and Tan,Y.Q.
  TITLE     CFAP65 is required in the acrosome biogenesis and mitochondrial
            sheath assembly during spermiogenesis
  JOURNAL   Hum Mol Genet 30 (23), 2240-2254 (2021)
   PUBMED   34231842
  REMARK    GeneRIF: CFAP65 is required in the acrosome biogenesis and
            mitochondrial sheath assembly during spermiogenesis.
REFERENCE   3  (bases 1 to 5718)
  AUTHORS   Liu,C., Tu,C., Wang,L., Wu,H., Houston,B.J., Mastrorosa,F.K.,
            Zhang,W., Shen,Y., Wang,J., Tian,S., Meng,L., Cong,J., Yang,S.,
            Jiang,Y., Tang,S., Zeng,Y., Lv,M., Lin,G., Li,J., Saiyin,H., He,X.,
            Jin,L., Toure,A., Ray,P.F., Veltman,J.A., Shi,Q., O'Bryan,M.K.,
            Cao,Y., Tan,Y.Q. and Zhang,F.
  TITLE     Deleterious variants in X-linked CFAP47 induce
            asthenoteratozoospermia and primary male infertility
  JOURNAL   Am J Hum Genet 108 (2), 309-323 (2021)
   PUBMED   33472045
REFERENCE   4  (bases 1 to 5718)
  AUTHORS   Zhang,D., Liu,C., Li,H. and Jiao,J.
  TITLE     Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to
            Neurogenic Abnormalities and Autistic-Like Behaviors
  JOURNAL   Adv Sci (Weinh) 7 (23), 2002117 (2020)
   PUBMED   33304758
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5718)
  AUTHORS   Li,W., Wu,H., Li,F., Tian,S., Kherraf,Z.E., Zhang,J., Ni,X., Lv,M.,
            Liu,C., Tan,Q., Shen,Y., Amiri-Yekta,A., Cazin,C., Zhang,J.,
            Liu,W., Zheng,Y., Cheng,H., Wu,Y., Wang,J., Gao,Y., Chen,Y.,
            Zha,X., Jin,L., Liu,M., He,X., Ray,P.F., Cao,Y. and Zhang,F.
  TITLE     Biallelic mutations in CFAP65 cause male infertility with multiple
            morphological abnormalities of the sperm flagella in humans and
            mice
  JOURNAL   J Med Genet 57 (2), 89-95 (2020)
   PUBMED   31501240
  REMARK    GeneRIF: Biallelic mutations in CFAP65 cause male infertility with
            multiple morphological abnormalities of the sperm flagella in
            humans and mice.
REFERENCE   6  (bases 1 to 5718)
  AUTHORS   Zhang,X., Shen,Y., Wang,X., Yuan,G., Zhang,C. and Yang,Y.
  TITLE     A novel homozygous CFAP65 mutation in humans causes male
            infertility with multiple morphological abnormalities of the sperm
            flagella
  JOURNAL   Clin Genet 96 (6), 541-548 (2019)
   PUBMED   31571197
REFERENCE   7  (bases 1 to 5718)
  AUTHORS   Shi,B., Xue,J., Zhou,J., Kasowitz,S.D., Zhang,Y., Liang,G.,
            Guan,Y., Shi,Q., Liu,M., Sha,J., Huang,X. and Wang,P.J.
  TITLE     MORC2B is essential for meiotic progression and fertility
  JOURNAL   PLoS Genet 14 (1), e1007175 (2018)
   PUBMED   29329290
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 5718)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
REFERENCE   9  (bases 1 to 5718)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Ccdc108 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133278.1.
            
            [WARNING] On Jul 10, 2024 this sequence was replaced by
            NM_001039495.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133278.1, BC150939.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5718              AK133278.1         2-5719
FEATURES             Location/Qualifiers
     source          1..5718
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 38.54 cM"
     gene            1..5718
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /note="cilia and flagella associated protein 65"
                     /db_xref="GeneID:241116"
                     /db_xref="MGI:MGI:2444274"
     exon            1..79
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            80..248
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..5663
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /note="coiled-coil domain-containing protein 108;
                     coiled-coil domain containing 108"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 65"
                     /protein_id="NP_001034584.1"
                     /db_xref="CCDS:CCDS15060.1"
                     /db_xref="GeneID:241116"
                     /db_xref="MGI:MGI:2444274"
                     /translation="MLIQKNQCHITRTRENCDCTMNTVNEDLCLSASTLGSSSVTTQL
                     VDPLDRKICLIRRQNDVKKRVIWGIEVAEKLHWKGWELGKETTRTLVLKNLSLKTQKM
                     KYRPPKTKFFFTIIPQPIFLSPGITLTLPIVFRPLEAKEYTDQLWFEKEEGVFCVTLK
                     ATLPCYKLDCPSSLQLPMCALGDTVETWFCLNNVGDLPTFFTWEVPAPFQILPTTGLL
                     EPGLGCKIKVTFEPLIAVIHEVEALCWYGKGNKQKNSINIQAAAKCAQLLVSIKHKGL
                     EDQDQEGFQKVVHFGYVSVGSVAERQIRLYNPSAVNAPFKIEMAEHVLTKDPSFSCST
                     SQGIVPPGEKKCLSLFFHPKTLDSRAIDYFSIIPSGCATKTLLQVVGFCRGPDAVLQH
                     SCVNFHWVKLGERREQTLWIENQSDCQAHFQFDIDCQESVFSIRPAFGTLAGKTRMTL
                     HCAYQPTHPIISFRRVACLIHHQDPLFLDLIGTCHSDSIKPAILTPQHLTWYRTHLAR
                     GLTLYPPDILAAMLKEKKLERDEDGALILPIESLPMQELEDLPDQKYPNIPPMTEYFF
                     DGTRDLAIFPPAVCLEPIDVDFGACPGPEAPNPVPLCLRNYTKGKITVVWTGRSDCPF
                     WVTPVTSDVPPLKSIALRLYFQPSSPNCLYAVELEAFAVYKVLQCYSNIEEDCTVVPS
                     WCLKVRARGHSYSPALEHHIPHYSLDSPQTFPAVSPGKPSYRSLFLVNKGSMLMTFSL
                     APNSSSDITLRPSSGLIGPGAHQVFLISTYPKGTSWRQHIFYLNFNFYPQYLKEVSMQ
                     SREEPLDLKLDTHKSIYFKPTWVGCSSTSNFTFHNPSRLPLQFEWRVSQEHQKVLAVQ
                     PSKGTIHPNENLTLTWIFSPLEEIKYLFRVGIWVWEARQSQKTKPQATVHYRIRLVGM
                     GVTGCLSAKPVELDFGNVLVNSQEVKPLVLLNDGNCTLYYRLVLEQHRPKGLHSDPCA
                     LEFDHSEGTMPPHSQDTIYLTARPKVRSQYSWTISYCLLSQRAPPTNSMDGKKKALCH
                     VSLAAAYPLLSVLDICSMGSTEGITRKHLWHLFSLDTLNSYLARDPTAKELTYKVPTR
                     HSMSRTPPIFTPLKLDFNFGAAPHNALPSVVLLVLKNCGLVPLDWAFLFPSDQQLDLD
                     LWVEQEDLNSNELHQMRAEDNSLFSINPKTGSLNPGQEQMVEFTYRHLFVGTDRLSVL
                     FKVSHGREILLQFIGVTVKLEQKYVHFTSTIHQFIPVPIGDTLPPRQIYELYNGGSVP
                     VTYEVQVSVLSKVQEKNFDHPIFCCLNPKGDIQPGTTARILWIFSPIEAKTYTVEVPI
                     HIIGWNSAVVCFQGVGYDPCVMGDTAPFHSISSWDSSSISSRLMVPGQNVFLSQSHIS
                     LGNIPVQSKCSRLFFLNNISKNETIVFTWKPRSLDFGEVTVSPMEGEVGPEEGAPILV
                     TLKASVHASFYSIDLICKVYQRELMRQYHKELQEWNEEKARQEVEFTITDRKVKRRAY
                     CAAHEPPKKYKTLPPITNQPPLNRPATWNLKLAKKETSWPCPQPPVPGLLCLGLTARA
                     HATDYYLANFFSEFPCHFLYRELPKKKSSKEESKSSEELPDKKGPVSRQKQQLLVDCL
                     TSIIRGLLEDKNFHNAVDQNLVEQVPYFCQFWNEQSARFLAQKSSLYLVPILSLPPSY
                     EGRKSKEQEEDLFGKMPGGQEDDEEEEEDEEEAEEEEEEIEEEMSKDEEDIDKDAKMT
                     WSGIKVTETSQHSLQWQWQQDLKTIIKEETESDEKEAIGRLPAFANLQEAILENMIQN
                     ILVEASRGEVVLTSRPRIIALPPVSMHRTDNLLQMSQGDVLCSGMQHPDCLLVSASSP
                     SNMTT"
     exon            249..433
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            434..536
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            537..703
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            704..903
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1049
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1272
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1538
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1739
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            1740..2114
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2252
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2498
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            2499..2723
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2882
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            2883..3033
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3034..3162
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3388
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3389..3517
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3518..3694
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3695..3761
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3762..3872
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            3873..4064
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4065..4223
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4224..4367
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4368..4481
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4482..4589
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4590..4634
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4635..4837
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4838..4963
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            4964..5416
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            5417..5554
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
     exon            5555..5718
                     /gene="Cfap65"
                     /gene_synonym="A230051F10; B230363K08Rik; Ccdc108"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcctgtatc tacggagacg ttagcacagc gtttgcatga gttctaaacg ttggaggcca
       61 gcgagaggaa caaggaacga ctcgtctgct gatctggtag ggatttttgg ctttgctaga
      121 tgctcatcca gaaaaaccaa tgccacatca cgaggaccag ggagaactgt gactgtacaa
      181 tgaacactgt gaatgaagat ttgtgcctga gtgccagcac actgggaagt agcagtgtca
      241 ccacccagct tgtagatccc ctggacagga aaatatgcct cataaggagg caaaatgatg
      301 tgaaaaagag ggtgatctgg ggcatcgagg tcgccgagaa gctgcactgg aaaggctggg
      361 agctgggaaa ggagaccaca agaaccctgg ttctgaaaaa cctctccctg aaaacccaga
      421 agatgaagta caggcctccc aagaccaagt tcttcttcac tatcattcca cagcccatct
      481 tcctgagccc aggcataacg ctcacacttc ccattgtctt ccgacctcta gaagcgaagg
      541 aatacacaga ccagttgtgg tttgaaaaag aagagggggt gttctgtgtg accctgaagg
      601 ccaccttgcc ttgctacaag ctagactgcc catcatctct gcaactgccc atgtgtgccc
      661 ttggggacac agtggagact tggttctgtc tgaacaatgt gggggacctg cccaccttct
      721 tcacctggga agtcccagcc ccatttcaga tactacccac tacggggtta ctggagccag
      781 gcctgggttg taagatcaaa gtgacctttg agcccctcat agctgtcatc catgaagttg
      841 aggcattgtg ctggtacgga aagggaaaca aacagaagaa cagcattaac atacaggctg
      901 cagctaaatg tgcacagctg ctggtgagca taaagcacaa ggggctagag gaccaggatc
      961 aggaaggctt ccagaaggtg gtacacttcg gctatgtctc cgtgggctcc gtcgcagagc
     1021 ggcaaatcag gctgtataac ccatctgcgg ttaacgcccc cttcaagata gaaatggccg
     1081 aacacgtgct gaccaaagac ccgagcttct catgttccac aagccaaggc attgtgcccc
     1141 cgggggagaa gaaatgcctg tcactgttct ttcaccccaa gactttggac agcagagcca
     1201 tcgactactt ctccatcata ccttctggct gtgccaccaa aactttgctc caggttgttg
     1261 gtttctgtag aggtcccgat gcagtgctgc agcactcctg tgtcaacttc cactgggtca
     1321 agctcgggga acgccgggaa cagactctgt ggattgagaa ccagtcagac tgccaggctc
     1381 acttccagtt tgatattgac tgccaggaga gtgtcttcag catcaggcct gcctttggaa
     1441 ccctggcagg caagactcgt atgaccctgc actgtgccta ccagcccact caccctatca
     1501 tcagtttccg gagggtggct tgtctcatcc atcaccagga cccactgttt ctggacctga
     1561 ttgggacctg ccattcagac agcatcaagc cagccatcct gacacctcag cacctcactt
     1621 ggtaccgaac acacctggct cggggcctga ccctctaccc tcctgacatt ctggctgcca
     1681 tgctaaagga gaaaaagctg gaacgggacg aggatggggc cctcatattg cccattgagt
     1741 ctctccctat gcaggaactg gaggacctgc cagaccaaaa gtaccccaat atccctccca
     1801 tgacggagta cttttttgac ggcaccaggg acctggccat ctttccccca gctgtctgtc
     1861 tagagcccat tgatgtggac tttggtgcct gtcctgggcc tgaagccccc aaccctgttc
     1921 ctttatgcct gaggaactat accaaaggca agatcaccgt ggtctggact ggcagatctg
     1981 actgcccttt ctgggtgacc ccagtcacta gtgacgtgcc cccactcaag tccatagccc
     2041 tgcgcctgta cttccagccg tcctctccca actgcctcta tgctgtggag ctagaagcct
     2101 tcgccgttta taaggtcctt cagtgctaca gcaatattga agaggactgc acagtggtcc
     2161 cgtcatggtg tctgaaggtt cgggctcgag gtcacagcta ttcccctgcc ttagaacacc
     2221 acatcccaca ctattccctg gattcacccc agacgttccc agcagtgtct cctggaaaac
     2281 cctcctacag aagcctgttt ttggtcaaca aaggctccat gctcatgacc ttcagcctgg
     2341 cccccaatag cagctcggac atcaccctga ggccctcctc tggcctcatc ggtcctggag
     2401 cccaccaggt cttccttata agcacatacc ccaagggcac ctcatggagg cagcacattt
     2461 tctacctgaa cttcaacttt tatccccagt acctcaagga agtgagcatg cagagcagag
     2521 aggagcccct ggatctgaag ctggacaccc acaaaagcat ctacttcaag cctacctggg
     2581 tgggctgttc ctccaccagc aacttcacct ttcacaaccc ctcacggctg cccctgcagt
     2641 ttgagtggag agtctcacaa gagcaccaaa aggtgctggc cgtccagccg tccaagggta
     2701 ccatccaccc taacgagaac ctcacactaa cgtggatctt cagccctctg gaggagatca
     2761 agtacctgtt ccgagtgggg atctgggtct gggaagccag acagtcacaa aagaccaaac
     2821 cccaagccac tgtgcactac aggattcggc tggtgggcat gggtgttact ggatgcctct
     2881 ctgcaaagcc agtggagctg gacttcggga acgtactggt gaacagccag gaagtcaagc
     2941 ctttggtgct cttgaatgac ggcaactgca ccctctatta ccgcctggtc ctggagcagc
     3001 acaggcccaa gggcctccac agtgacccct gtgctctaga attcgaccac tcggaaggga
     3061 ccatgccgcc tcattcccag gataccatct acctgactgc ccgtccaaaa gtccgttccc
     3121 aatattcctg gaccattagc tactgtctcc tgtcccagag agcccctccc accaacagca
     3181 tggatggcaa aaagaaagcc ctgtgccacg tgtccctggc agctgcatat cctttactct
     3241 ccgtcctgga tatctgctcc atgggtagca ccgagggcat cactcgcaag cacctgtggc
     3301 acctcttctc cctggacacc ctcaatagtt acttggcacg tgacccaact gccaaggagc
     3361 tcacctacaa ggtgcccact cggcacagca tgagccgtac accccccatc ttcactcctc
     3421 tgaagctgga cttcaatttt ggagcagcgc cacacaatgc cctgccctca gtggtactcc
     3481 tcgtactgaa gaactgtggg ctggtgccct tggactgggc tttcctcttt ccaagtgacc
     3541 agcagctgga cctggatctg tgggtagagc aggaagacct caacagcaat gagctccacc
     3601 aaatgcgtgc agaggacaat tccctcttct ccatcaaccc caagactggg agcttgaacc
     3661 ctgggcagga gcagatggta gagttcacat acagacacct gtttgtcggc accgatcgcc
     3721 tttctgtgct cttcaaggtg tcccatggac gggaaatcct gctacagttc atcggcgtga
     3781 cggtgaagct ggagcagaag tatgtgcact tcacctctac catccaccag ttcattcctg
     3841 tccccatcgg ggacacactg cccccacgcc agatttacga gctgtacaat ggcggctcag
     3901 tacctgtgac atatgaggtc caggtcagcg ttctgtcaaa ggttcaagaa aaaaattttg
     3961 accatcctat tttctgctgc ctgaacccca aaggggacat ccagccaggt actactgctc
     4021 ggatcctgtg gatcttctca cccatcgagg ccaagaccta cacggtggag gtacccatac
     4081 acatcattgg atggaactca gcggtcgtct gcttccaagg agtaggatat gacccctgtg
     4141 tcatgggtga caccgcccct ttccacagca tctcttcgtg ggacagcagt tccatatcct
     4201 ctaggttgat ggttcctggg cagaatgtct tcctgtccca gtctcacatc tccctgggaa
     4261 acatccctgt gcagagcaag tgtagccgcc tgttttttct caacaacatc tccaagaatg
     4321 agacaattgt cttcacctgg aagccaaggt ccttagactt tggagaggta actgtgagtc
     4381 ccatggaagg agaagtgggt cctgaagagg gagccccaat cctagtgacc ctgaaggcct
     4441 cggttcatgc cagcttctac agcatagact tgatatgcaa ggtataccag cgggaactta
     4501 tgcggcagta tcacaaggag ctacaggaat ggaatgaaga gaaggctcga caggaggtgg
     4561 agttcaccat cacagatcgg aaagtaaaga ggagagcata ctgtgcagcc catgaacccc
     4621 caaagaagta caagacgctg cctcccatca caaaccaacc gcctctcaac cggcctgcta
     4681 cctggaacct gaaattggca aagaaggaga catcatggcc atgccctcaa ccccctgtgc
     4741 caggcctgct gtgtctaggc ctcaccgcaa gggcccatgc cacagactac tacctggcca
     4801 acttcttctc tgagttcccc tgccacttcc tgtaccggga gctgccaaag aagaaatcct
     4861 ccaaggaaga gtcaaaatct tctgaagaac tccctgacaa aaagggtcct gtctctcggc
     4921 agaagcagca gcttctggtg gactgcctca ccagcatcat ccggggtcta ttggaagaca
     4981 agaatttcca taatgctgtg gaccaaaacc tggtggagca ggtgccttac ttctgccagt
     5041 tctggaatga gcagtcagcc aggttcctag cccagaaaag cagcttgtac ttagtgccga
     5101 tcctgtccct gccgcccagc tatgagggca ggaaaagcaa ggagcaggag gaggaccttt
     5161 ttgggaagat gccagggggg caagaggatg atgaagagga agaggaagat gaggaggagg
     5221 cagaagagga agaggaggag atagaagagg agatgagcaa ggacgaggag gacatagaca
     5281 aggatgcaaa gatgacctgg tcagggatta aggtcacaga gacctcccag cactctctgc
     5341 agtggcaatg gcagcaggat ctgaagacca taataaagga ggagacagaa agtgacgaga
     5401 aggaggccat tgggaggcta ccagcttttg ccaacctgca ggaagcaata ctggagaaca
     5461 tgattcagaa catcctggta gaggcaagcc gtggagaggt agtgctcact tcgaggcccc
     5521 gcatcattgc cctaccacca gtcagcatgc acaggacaga caacctcttg cagatgtcac
     5581 aaggggacgt gctctgctct gggatgcagc atcctgactg tttgctggtg tcagcatcca
     5641 gcccctctaa catgactacc taaattgccc ctggtccctt ttttttctta ctgttctgca
     5701 agtaaaccat taagttcc
//
