LOCUS       NM_001163267            3345 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus cilia and flagella associated protein 58 (Cfap58),
            mRNA.
ACCESSION   NM_001163267 XM_001481322 XM_355166
VERSION     NM_001163267.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3345)
  AUTHORS   Wei,X., Wang,X., Yang,C., Gao,Y., Zhang,Y., Xiao,Y., Ju,Z.,
            Jiang,Q., Wang,J., Liu,W., Li,Y., Gao,Y. and Huang,J.
  TITLE     CFAP58 is involved in the sperm head shaping and flagellogenesis of
            cattle and mice
  JOURNAL   Development 151 (7) (2024)
   PUBMED   38602507
  REMARK    GeneRIF: CFAP58 is involved in the sperm head shaping and
            flagellogenesis of cattle and mice.
REFERENCE   2  (bases 1 to 3345)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3345)
  AUTHORS   He,X., Liu,C., Yang,X., Lv,M., Ni,X., Li,Q., Cheng,H., Liu,W.,
            Tian,S., Wu,H., Gao,Y., Yang,C., Tan,Q., Cong,J., Tang,D.,
            Zhang,J., Song,B., Zhong,Y., Li,H., Zhi,W., Mao,X., Fu,F., Ge,L.,
            Shen,Q., Zhang,M., Saiyin,H., Jin,L., Xu,Y., Zhou,P., Wei,Z.,
            Zhang,F. and Cao,Y.
  TITLE     Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar
            Axoneme and Mitochondrial Sheath Defects and
            Asthenoteratozoospermia in Humans and Mice
  JOURNAL   Am J Hum Genet 107 (3), 514-526 (2020)
   PUBMED   32791035
  REMARK    GeneRIF: Bi-allelic Loss-of-function Variants in CFAP58 Cause
            Flagellar Axoneme and Mitochondrial Sheath Defects and
            Asthenoteratozoospermia in Humans and Mice.
REFERENCE   4  (bases 1 to 3345)
  AUTHORS   Li,Z.Z., Zhao,W.L., Wang,G.S., Gu,N.H. and Sun,F.
  TITLE     The novel testicular enrichment protein Cfap58 is required for
            Notch-associated ciliogenesis
  JOURNAL   Biosci Rep 40 (1) (2020)
   PUBMED   31904090
  REMARK    GeneRIF: The novel testicular enrichment protein Cfap58 is required
            for Notch-associated ciliogenesis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126679.2 and AC127264.4.
            
            On or before Jul 15, 2009 this sequence version replaced
            XM_001481322.1, XM_355166.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057135.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               AC126679.2         63452-63576         c
            126-407             AC126679.2         59896-60177         c
            408-556             AC126679.2         57050-57198         c
            557-713             AC126679.2         53016-53172         c
            714-908             AC126679.2         51808-52002         c
            909-1046            AC126679.2         48164-48301         c
            1047-1206           AC126679.2         45836-45995         c
            1207-1289           AC126679.2         43086-43168         c
            1290-1481           AC126679.2         38722-38913         c
            1482-1643           AC126679.2         26609-26770         c
            1644-1790           AC126679.2         25680-25826         c
            1791-1931           AC126679.2         19129-19269         c
            1932-2155           AC126679.2         17617-17840         c
            2156-2267           AC126679.2         14736-14847         c
            2268-2372           AC126679.2         12719-12823         c
            2373-2492           AC127264.4         73650-73769         c
            2493-2626           AC127264.4         71277-71410         c
            2627-3345           AC127264.4         65110-65828         c
FEATURES             Location/Qualifiers
     source          1..3345
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 40.6 cM"
     gene            1..3345
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /note="cilia and flagella associated protein 58"
                     /db_xref="GeneID:381229"
                     /db_xref="MGI:MGI:2685815"
     exon            1..125
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..2738
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /note="coiled-coil domain containing 147"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 58"
                     /protein_id="NP_001156739.1"
                     /db_xref="CCDS:CCDS50466.1"
                     /db_xref="GeneID:381229"
                     /db_xref="MGI:MGI:2685815"
                     /translation="MTEDKAEKVMPEETAFEEIEKDFQEVLSELSGDKSLEKFRTEYE
                     KLHSIMKKSYENEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKA
                     WKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTK
                     ERDQLLSEVVKLRENLAQTIEKQQAAEHAKEEAEMAISQFQQEIQHRQNEASRESRKK
                     EKLEKELRQIQTDMDGRQAEIKAMQQYMHKSKEELQRLEQQLKEQKILNERAAKEVEQ
                     FQMRNAKLQQENDQHTLTCEQLSQENQQKALELKAKEDEIHQMRLDLGKLNKIREQIH
                     KKLHQLDDQKAEVEQQKDTLKNQILGLEREVESSKKQAELDKKAMEELLRERDILNKN
                     MLKAVSATQKQVDLVKLHEQAKKNLEEEIQNYKDEAQKQRKIIFQLEKERDRYINEAS
                     DLTQRVLANMEDIKVREIQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEA
                     QDEITEMKRKLKIMTHQVDQLKEEISAKEAALVKLHLEQQRIEKEKETLKAELQKLRQ
                     QALETKHFIEKQEVEERKLLRIIAEADGERVRQKKELDQVISERDILGSQLVRRNDEL
                     ALLYEKIKIQQSVLNKGETQYNQRVEDMRILKLEIKKLRREKGILARSVANVEELRQE
                     LYHMQREFLKERTRCRALEEELENPMNVHRWRKLEASDPSTFELIQKIHTLQKRLISK
                     TEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSEL
                     NMYESQSQEYKYEIERLGNELMSLKKKYLAQKRKELVLKNKDRMSMNNIFSETKKSVP
                     RFTGGGFPLHQATKVKF"
     exon            126..407
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            408..556
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            557..713
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            714..908
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1046
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1206
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1289
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1481
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1643
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1644..1790
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1931
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..2155
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2267
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            2268..2372
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            2373..2492
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            2493..2626
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
     exon            2627..3345
                     /gene="Cfap58"
                     /gene_synonym="Ccdc147; Gm969"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaaaacgtg tcgccctttt agacactggg ggcagtgcac agccccttct ccagactcca
       61 gcccagtttt ctgatctcct cggcagcctt tgaggccgcc tccaaacagc gtcaggatga
      121 cggaggacaa ggctgaaaaa gtaatgccgg aggaaactgc atttgaagaa atcgagaaag
      181 attttcagga ggttctcagc gaactttcag gagacaaaag tctggaaaaa ttcaggaccg
      241 aatatgagaa acttcactcc atcatgaaaa agtcttacga gaatgagaag cgtctcatgg
      301 ccaagtgcag agagctgaac gcagagattg tggtgaactc ggccaaggtt gccacagctc
      361 tgaagctctc tcaggacgac cagaccacca tcgcatccct taagaaggaa atcgagaaag
      421 cctggaagat ggtggactcg gcatatgaca aggagcaaaa ggccaaggag acaattcttg
      481 ccctgaagga ggaaatagtg aacctgacca aactagttga gcaggggtct ggactgtcaa
      541 tggatcagga cagcaacatc cgagatttac tgaagttcaa agaagaggtg acgaaggagc
      601 gtgaccagct cttgtcagaa gtggtgaaat tgcgggagaa cctagctcag accatcgaaa
      661 agcagcaggc agcagagcac gccaaggaag aagctgaaat ggccatcagt cagttccaac
      721 aagaaatcca gcatcgtcag aatgaagctt ccagggagtc tcggaagaag gagaagctgg
      781 agaaagagct caggcagatc cagacggaca tggacggcag gcaggcggag atcaaggcta
      841 tgcagcagta tatgcacaag agcaaggagg aacttcagcg gctggaacag cagctcaagg
      901 agcagaagat actgaacgag agagctgcga aggaggtgga acagtttcag atgcggaacg
      961 cgaaactgca gcaagagaat gatcagcaca ctctgacttg tgagcagctg tcgcaggaaa
     1021 accagcagaa ggccctggag ctcaaagcca aagaggatga gatccaccag atgcgcctcg
     1081 accttgggaa gcttaacaag atccgcgagc agatccacaa gaaactgcac cagctcgatg
     1141 accaaaaggc agaagtggag cagcagaagg acaccctgaa gaaccagatc ctagggctgg
     1201 agagagaggt ggagtcttca aagaagcaag cggagcttga taagaaggca atggaggagc
     1261 ttctgagaga gagagacata ctgaacaaga atatgctcaa ggcggtcagt gcgacccaga
     1321 agcaggtgga cctggtgaaa ctccacgagc aagccaagaa gaacctggag gaggagatcc
     1381 agaactacaa ggacgaggcc cagaagcaga ggaagatcat ctttcagctg gaaaaggaac
     1441 gggaccggta catcaacgag gccagcgacc tcacccagag ggtccttgca aacatggaag
     1501 acattaaagt ccgagaaata cagatttttg actacaggaa gaaaattgcc gaatcagaga
     1561 cgaagttaaa acagcagcaa aacctgtatg aagctgtgag atcagacagg aacctgtaca
     1621 gcaaaaacct ggtggaggct caggatgaaa tcacagaaat gaagaggaag ttaaagatca
     1681 tgacgcatca agtggaccag ctgaaggaag aaatctctgc caaggaagcc gcgctcgtga
     1741 agctgcatct ggaacagcag cgcattgaga aggagaaaga aacattgaag gccgagctac
     1801 agaagctgag acaacaagcc ctggagacca aacacttcat tgaaaagcag gaggtagaag
     1861 agaggaaact cttgcgcatc attgccgagg ctgacggcga gagggtgagg cagaagaagg
     1921 agttggacca ggtcatcagt gagagagaca tcctggggtc tcaacttgtc cggcgaaacg
     1981 atgagttagc cttgctctat gagaagatta agatccaaca gtcagtgctg aacaaaggcg
     2041 agacccagta caaccagcgg gtggaggaca tgcgcatcct caaactggag atcaagaagc
     2101 tccgaaggga gaaggggatc cttgccagga gtgtggccaa tgtggaggag ctcaggcagg
     2161 agctgtacca catgcaaaga gaattcctga aggaaaggac gaggtgccga gccctggagg
     2221 aggagctgga gaaccccatg aacgtgcaca gatggagaaa gcttgaggcc agcgacccta
     2281 gcaccttcga gctgatccag aaaatccaca ccctgcagaa gcgactcatc agcaagacgg
     2341 aagaggtggt ggaaaaagag ctgcttcttc aggagaaaga gaagctgtat gtggagctga
     2401 agcacatctt ggcccggcag cctggcccag aggctgcgga gcagctgcag atctaccggc
     2461 atacactgcg cgagaagact aagcagctga aagttctgtc atcggagttg aatatgtacg
     2521 agtcacagag ccaggagtac aagtatgaga tcgagagact tggcaatgaa ctgatgtctt
     2581 taaagaagaa atacctggct cagaaacgca aagaactcgt tctgaaaaac aaggacagga
     2641 tgtcgatgaa caacatcttc tcagagacca agaagtccgt ccctcggttt accgggggtg
     2701 gatttcccct ccaccaggca accaaggtga agttttaacc ggaagctact ggctggctca
     2761 agctcaacag ctcaggaaat ttgcgctgga acattgtaga ggaatcgcct tcaatccctc
     2821 aaatcatagc tagatagaaa aagccggtgc ccagcttttc agagttggaa gggatgggca
     2881 gctgtcagtg tcttgtacat acaagtgatg atgtcgtacc tgaagcacgt ggacagtaac
     2941 agactgtgat tgcagctctc taattaagat ggcccttggc ataaagctga tcttttgtta
     3001 cagttgaatc agctgattag aaatgcacta gatttagaaa cttggggtgg atgaagcttt
     3061 gggtattaat tcctctatta tagatatttg agcacttgaa ggtttttgta tgcaaaaaaa
     3121 tattttatat gttaaaaatg caatgcatgc cctcacatct tattagtgaa aatctatttt
     3181 aattattcct cattagcaag tgatagcatg agataggata acaggacaca tgactgggat
     3241 ttcaaaaagt gtatattgag agtgatttcc acgtgggaca tcgttccagg cctggggtag
     3301 gaaaatctgt tctgaagaag aaatgccaat aaatacttca tcata
//
