LOCUS       NM_199017               1644 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus cilia and flagella associated protein 300 (Cfap300),
            transcript variant 1, mRNA.
ACCESSION   NM_199017 XM_134629
VERSION     NM_199017.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1644)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1644)
  AUTHORS   Li-Villarreal,N., Rasmussen,T.L., Christiansen,A.E., Dickinson,M.E.
            and Hsu,C.W.
  TITLE     Three-dimensional microCT imaging of mouse heart development from
            early post-implantation to late fetal stages
  JOURNAL   Mamm Genome 34 (2), 156-165 (2023)
   PUBMED   36595063
  REMARK    Review article
REFERENCE   3  (bases 1 to 1644)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB855089.1, BY786171.1 and AK033793.1.
            
            On Nov 23, 2017 this sequence version replaced NM_199017.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033793.1, SRR1660821.39466.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                BB855089.1         3-23
            22-52               BY786171.1         20-50
            53-1644             AK033793.1         2-1593
FEATURES             Location/Qualifiers
     source          1..1644
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 2.46 cM"
     gene            1..1644
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="cilia and flagella associated protein 300"
                     /db_xref="GeneID:234912"
                     /db_xref="MGI:MGI:3045346"
     exon            1..206
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..900
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C11orf70 homolog"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 300
                     isoform 1"
                     /protein_id="NP_950182.1"
                     /db_xref="CCDS:CCDS22813.1"
                     /db_xref="GeneID:234912"
                     /db_xref="MGI:MGI:3045346"
                     /translation="MAAGEPRDGGGYYFRFLPHRTFSSLSAREITSRLRQWSMLGRIQ
                     AQAFSFDQTFQPYQKDDFVMAFFKDPNVIPNLQLLSDSSGQWTTLGSEVKKIEAINVP
                     CTQLSMSFFQRLYDENIVRESGHIVKCLDSFCDPFLISDELRKVLLMEDSEKYEVFSP
                     VEREEFLFCLFKHLCLGGSLCQYEDVLKPYLETAKLIYKDLVSVRKHPRTKEIQITSS
                     VFKVKAYDSVGVCYPSPKEHEQTFSYFVVDPIKRHVNVLYHCYGVGHMA"
     exon            207..288
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            289..364
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            365..531
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            532..704
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            705..771
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            772..1644
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      918..923
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="hexamer: ATTATA"
     polyA_site      938
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="major polyA site"
     regulatory      1365..1370
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1384
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="major polyA site"
     regulatory      1430..1435
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
                     /note="hexamer: ATTACA"
     polyA_site      1449
                     /gene="Cfap300"
                     /gene_synonym="9230110C19Rik"
ORIGIN      
        1 tctgagcggc gcccctcccc ctgaacgtgg tggcaggtcc taccgctgtg tcactatgga
       61 aacgactact gctttcttac cctggtcata agcaggatgg cggctgggga gccacgggat
      121 ggaggcggct actacttcag attcctgcct catagaacct tctcgtcgct gagcgcccgg
      181 gagatcacca gccgcctccg ccagtggtcc atgctgggca gaatccaggc gcaggcgttc
      241 agcttcgacc agacgttcca gccctaccaa aaggatgatt ttgtcatggc ttttttcaaa
      301 gacccaaatg ttattccaaa tttgcagtta ctctcagatt cttctggaca gtggaccaca
      361 ttaggatctg aagtgaaaaa aattgaagct ataaatgttc catgcacaca actttcaatg
      421 tcatttttcc aacgcttata cgatgaaaat attgtacgag aaagtggaca cattgtcaaa
      481 tgcctagatt ctttctgtga tccgtttctc atttcagacg aactgagaaa agttttgctc
      541 atggaagact ctgaaaaata tgaagtcttt agcccagtgg aaagggaaga gtttctgttc
      601 tgtcttttta agcatctctg cctcggaggg tccctttgtc agtatgaaga tgtgctaaag
      661 ccatatctgg agacagctaa gctgatctat aaggatctgg tgagtgttcg gaaacatcct
      721 cgaaccaagg aaatacaaat tacctcttct gtctttaaag taaaagccta cgactctgtt
      781 ggtgtgtgct acccttcacc taaagagcat gagcagacat tctcgtattt tgttgtggac
      841 cccatcaagc gtcatgtgaa tgtcctgtac cactgctatg gtgtagggca catggcttag
      901 gattgtttaa gccatctatt atactgttct ttacttcact gtgtctctgt gtcagcacga
      961 acaggtagat ctatgggctc tttgcagacc aatcaaaggc cactgtaaag agcccatatt
     1021 gagctgaaga gaacaaacac caaagtgccc ttttctcaat tttcccagca tacttgtgct
     1081 ggaatcccgg atagattctg tacaaagtag aaagtcacaa ggtcatgttt gttctattaa
     1141 gattcagcca cattcctaat ttcctttttt aaaagttgtt tttagttttt ttgaagatct
     1201 gtctcattta ccctaggata ggtgagcctt gaacttactt tgtaggtaag gctggtcttg
     1261 aactcctgat catcgtgcct ctaccttttg agcattgtaa tacaaacatg gaccaccagg
     1321 cctggccttt gagaagctaa ttgtctctgg attagaatag aaacattaaa catctccacc
     1381 accagccatt aatgtgaatt aatatgacta tttgacttca gttcatgtaa ttacattttt
     1441 ataattgcag aaaggtttat gtcttgttgg cgtgatactc gagggaatag cagcggttct
     1501 ctatgagttc aaggccagcc tggtctacag agcaagttct aggatagtca gggctacaca
     1561 gagaaaccct gtcttgaaaa gtaaaaaagg tttatatctc tacagatagg ataaacatag
     1621 aattcttttg ctttattttt ccac
//
