LOCUS       NM_001077684            1798 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Mus musculus cilia and flagella associated protein 210 (Cfap210),
            transcript variant 1, mRNA.
ACCESSION   NM_001077684 XM_130326 XM_910123 XM_992711
VERSION     NM_001077684.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Tai,L., Yin,G., Huang,X., Sun,F. and Zhu,Y.
  TITLE     In-cell structural insight into the stability of sperm microtubule
            doublet
  JOURNAL   Cell Discov 9 (1), 116 (2023)
   PUBMED   37989994
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  AUTHORS   Chen,Z., Shiozaki,M., Haas,K.M., Skinner,W.M., Zhao,S., Guo,C.,
            Polacco,B.J., Yu,Z., Krogan,N.J., Lishko,P.V., Kaake,R.M.,
            Vale,R.D. and Agard,D.A.
  TITLE     De novo protein identification in mammalian sperm using in situ
            cryoelectron tomography and AlphaFold2 docking
  JOURNAL   Cell 186 (23), 5041-5053 (2023)
   PUBMED   37865089
REFERENCE   3  (bases 1 to 1798)
  AUTHORS   Zhou,L., Liu,H., Liu,S., Yang,X., Dong,Y., Pan,Y., Xiao,Z.,
            Zheng,B., Sun,Y., Huang,P., Zhang,X., Hu,J., Sun,R., Feng,S.,
            Zhu,Y., Liu,M., Gui,M. and Wu,J.
  TITLE     Structures of sperm flagellar doublet microtubules expand the
            genetic spectrum of male infertility
  JOURNAL   Cell 186 (13), 2897-2910 (2023)
   PUBMED   37295417
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845261.17.
            
            On Mar 23, 2023 this sequence version replaced NM_001077684.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016309.1, BC125570.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849381,
                                           SAMN00849382 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               AL845261.17        106277-106391       c
            116-342             AL845261.17        104022-104248       c
            343-516             AL845261.17        98807-98980         c
            517-710             AL845261.17        98501-98694         c
            711-867             AL845261.17        94922-95078         c
            868-1007            AL845261.17        92992-93131         c
            1008-1200           AL845261.17        88794-88986         c
            1201-1365           AL845261.17        78584-78748         c
            1366-1798           AL845261.17        74895-75327         c
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 40.95 cM"
     gene            1..1798
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /note="cilia and flagella associated protein 210"
                     /db_xref="GeneID:75051"
                     /db_xref="MGI:MGI:1923100"
     exon            1..115
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1710
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 173; protein
                     CFAP210; coiled-coil domain containing 173"
                     /codon_start=1
                     /product="cilia- and flagella- associated protein 210
                     isoform 1"
                     /protein_id="NP_001071152.1"
                     /db_xref="CCDS:CCDS38138.1"
                     /db_xref="GeneID:75051"
                     /db_xref="MGI:MGI:1923100"
                     /translation="MQVRFGRRSGQAKESQGMDCFEKEEIPYPPLLPSKVDLQQITII
                     PHAEWERIRDSLNRLTREAAVLRAERAAKKKMHVKSQELVKHWTNTYAGMKEQKLKAK
                     QKRDEEIEAERKVLDLEEEIYKEGERKKAIESARQCQFHQTERVKRFHSGLLLSRVMK
                     ERDVQIQYKKNAVKSDKKWEEQVKLNDEKAFKEDQEKEEKRRRERVALAEDHLKQIEE
                     HKEEEEARKKSEEKDAEEMKRQNLLYEIEMKKNLSKKQEEIDTNRKLLLDNMHNKNII
                     RAVEQQQQEEEDEKIRKFIKAKKRLIQMRMDKDAETHRLMEERRERINNFLSKLIKEK
                     LDTEDLIIARDISEADAELEKREKEKHEKNQADLKAIAEYRASVMKNKEEEERQRKIE
                     AKEQLQAVLKADKIFQELEKEKSLKVTREKLEIQDAHIQQIAINKYNAKQMKEEELDY
                     WRLTDALTVEKEKEFEKYAREVINFESESTKKYAYPMVKAVQEGVGGGRGPPFVGRGG
                     IRPSYQATDATGVQLPCFKSQGSKYNDFQKSKRRLGFTW"
     exon            116..342
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            343..516
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            517..710
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            711..867
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            868..1007
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1200
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1365
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1798
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1776..1781
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /note="hexamer: AATAAA"
     polyA_site      1798
                     /gene="Cfap210"
                     /gene_synonym="4930525K21Rik; 4930578N16Rik; Ccdc173"
                     /note="major polyA site"
ORIGIN      
        1 agtagctgac ttcagcttgg aagtagtatc acctgctctg gactcgcggg atcagctttg
       61 ttaaagatgc aggtgcgctt tggacggcgc tccgggcagg cgaaggaaag ccaaggaatg
      121 gattgctttg aaaaagaaga gattccctat ccacccctcc tacctagcaa ggtggatctc
      181 cagcagatca ccataatccc acacgctgag tgggagagga tccgggatag cctcaacagg
      241 ttgacaagag aagcagcagt ccttcgtgca gaaagagcag caaagaagaa aatgcatgtg
      301 aaatcccaag agttggtaaa acactggact aacacatatg caggaatgaa agaacagaaa
      361 cttaaagcca agcaaaagcg tgatgaagag attgaggctg aaagaaaagt tcttgatctg
      421 gaggaagaaa tatacaaaga aggagaaaga aagaaggcca ttgagagtgc taggcagtgc
      481 cagtttcacc agacggagcg agtgaagcgc tttcactcag gacttcttct cagcagagtt
      541 atgaaagagc gtgatgtcca gattcagtac aaaaagaatg cagtgaaatc agataaaaaa
      601 tgggaggagc aagtgaagct caacgatgaa aaagctttta aagaagacca agagaaagaa
      661 gaaaaacggc gcagagaaag agtagctctt gccgaggatc atctgaaaca aattgaggaa
      721 cacaaagagg aagaagaagc aagaaagaaa agtgaagaaa aagatgctga ggagatgaag
      781 cggcagaatt tgctgtatga aatcgagatg aagaaaaacc taagcaagaa acaggaagag
      841 atagatacaa acaggaaact gcttcttgac aatatgcaca ataaaaacat catccgagct
      901 gtagaacaac agcagcaaga ggaggaagac gaaaagatta gaaagtttat caaagccaaa
      961 aaacgtctta tacaaatgag gatggacaaa gatgctgaaa cacataggct aatggaagaa
     1021 cggagagaaa gaataaataa tttcctaagt aaactaataa aagagaaact tgatactgaa
     1081 gatttgatta ttgctagaga tatttctgaa gctgatgctg aactggagaa aagagaaaaa
     1141 gaaaaacatg aaaaaaatca agcagacttg aaagcaattg cagaatatag agcctctgtg
     1201 atgaaaaata aagaggaaga agaaagacaa aggaaaatag aggctaagga acaattgcag
     1261 gctgtcttga aggcagataa gatcttccag gagcttgaaa aggagaaaag cctcaaagtg
     1321 accagagaga aactggaaat tcaggatgct cacattcagc aaatagccat aaataaatat
     1381 aatgcaaaac aaatgaagga agaagaatta gattattgga gacttactga cgcccttaca
     1441 gttgagaagg agaaagaatt tgagaagtat gctagagaag taattaactt tgaatctgaa
     1501 tcaacaaaga aatacgccta ccctatggta aaagctgtgc aggaaggagt gggaggtgga
     1561 cgtggaccac cctttgtagg cagaggtggg ataaggccaa gctatcaggc aactgatgcc
     1621 actggggtcc agctcccttg ttttaaaagt caaggatcaa agtataatga ttttcagaag
     1681 tcgaagagaa ggctaggttt tacttggtaa aaaaggtcat attttgatta ataaaattta
     1741 ctgtaatgag ctacaaatat aatggaattt ctgataataa agagactact tatgtgtt
//
