LOCUS       NM_029335               1310 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus cilia and flagella associated protein 161 (Cfap161),
            mRNA.
ACCESSION   NM_029335
VERSION     NM_029335.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1310)
  AUTHORS   Tai,L., Yin,G., Huang,X., Sun,F. and Zhu,Y.
  TITLE     In-cell structural insight into the stability of sperm microtubule
            doublet
  JOURNAL   Cell Discov 9 (1), 116 (2023)
   PUBMED   37989994
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1310)
  AUTHORS   Chen,Z., Shiozaki,M., Haas,K.M., Skinner,W.M., Zhao,S., Guo,C.,
            Polacco,B.J., Yu,Z., Krogan,N.J., Lishko,P.V., Kaake,R.M.,
            Vale,R.D. and Agard,D.A.
  TITLE     De novo protein identification in mammalian sperm using in situ
            cryoelectron tomography and AlphaFold2 docking
  JOURNAL   Cell 186 (23), 5041-5053 (2023)
   PUBMED   37865089
REFERENCE   4  (bases 1 to 1310)
  AUTHORS   Zhou,L., Liu,H., Liu,S., Yang,X., Dong,Y., Pan,Y., Xiao,Z.,
            Zheng,B., Sun,Y., Huang,P., Zhang,X., Hu,J., Sun,R., Feng,S.,
            Zhu,Y., Liu,M., Gui,M. and Wu,J.
  TITLE     Structures of sperm flagellar doublet microtubules expand the
            genetic spectrum of male infertility
  JOURNAL   Cell 186 (13), 2897-2910 (2023)
   PUBMED   37295417
REFERENCE   5  (bases 1 to 1310)
  AUTHORS   Beckers,A., Fuhl,F., Ott,T., Boldt,K., Brislinger,M.M.,
            Walentek,P., Schuster-Gossler,K., Hegermann,J., Alten,L.,
            Kremmer,E., Przykopanski,A., Serth,K., Ueffing,M., Blum,M. and
            Gossler,A.
  TITLE     The highly conserved FOXJ1 target CFAP161 is dispensable for motile
            ciliary function in mouse and Xenopus
  JOURNAL   Sci Rep 11 (1), 13333 (2021)
   PUBMED   34172766
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1310)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
REFERENCE   7  (bases 1 to 1310)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: 1700026D08Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116389.12, AK006375.1, EU234011.1 and AW047638.1.
            
            On Nov 17, 2009 this sequence version replaced NM_029335.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061016.1, AK006375.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                AC116389.12        72112-72124
            14-557              AK006375.1         2-545
            558-1292            EU234011.1         216-950
            1293-1310           AW047638.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 47.74 cM"
     gene            1..1310
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /note="cilia and flagella associated protein 161"
                     /db_xref="GeneID:75556"
                     /db_xref="MGI:MGI:1922806"
     exon            1..98
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..941
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 161"
                     /protein_id="NP_083611.2"
                     /db_xref="CCDS:CCDS21413.1"
                     /db_xref="GeneID:75556"
                     /db_xref="MGI:MGI:1922806"
                     /translation="MAQNVYGPGVRMGNWNEDVYLEEERMRHFLEKREKGELLIQRNR
                     RVKKNILRPMQLSVSEDGYVHYGDKVIIVNPDQVLGEEAGKFMRGDLSLCMSPDEVKA
                     QLSDDLEIPCGVSAVQTIAPMGRNTFTILSDGANSCEMGQVVVYGQNFCLGIAAGLEG
                     KMLYLTSDHRTLLKSSLKSGLQEVTLTDEVTHLNCWQAAFLDPQLRLEYEGFPVRANE
                     KIVIYHRHTNRALAVHRNLFLRTYFGKEMEVVAHTYLDSHKVEKPKNQWMLVTGNPRN
                     KSNTMLDISKPITEDTRALEQAMGINT"
     exon            99..188
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            189..424
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            425..515
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            516..674
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            675..748
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            749..1294
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1274..1279
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1294
                     /gene="Cfap161"
                     /gene_synonym="1700026D08Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggagctggct ttcaagagag caaggggcga tggcgcagaa cgtgtatggt cctggagtgc
       61 ggatgggcaa ctggaacgaa gatgtctatt tggaggagga gcgcatgaga cacttcctag
      121 agaagaggga aaaaggagaa cttcttattc agagaaacag aagagtgaag aagaacattt
      181 tgagaccgat gcagctttcg gtatcggaag atggatatgt ccactatggc gataaagtga
      241 tcattgtgaa tcctgaccaa gtcctggggg aggaagctgg caagtttatg agaggagacc
      301 tgagcctgtg tatgagccca gatgaagtta aagcgcagct tagtgatgac ttagagatac
      361 cctgtggtgt gagtgctgtg cagaccatcg ccccgatggg caggaacacc ttcaccattt
      421 tgagtgacgg cgcaaacagc tgcgaaatgg gccaagtggt tgtctatggg cagaacttct
      481 gcctggggat agcagcagga ctggaaggca agatgctgta tctaacaagt gaccacagga
      541 cccttttgaa gtcttctctg aagtccggcc tacaggaggt gactctgaca gatgaggtca
      601 cccatctgaa ctgctggcag gctgccttcc tcgatcccca gctgcgcctg gaatatgagg
      661 gcttcccagt gagggcaaat gaaaaaattg tcatctatca tcgtcacaca aaccgagccc
      721 tggcggtcca ccggaatctc ttcttaagga cctactttgg gaaggaaatg gaggttgtag
      781 ctcacacata tctggactca cacaaagtag aaaaacccaa gaaccagtgg atgctggtta
      841 ctggaaatcc caggaacaag tcgaacacca tgctagacat ctccaaaccc atcacagagg
      901 atacgcgcgc cttggagcag gccatgggca tcaatacata gtgacatacc aggcgtacag
      961 gtggcctctc aggctctgat ctcatcaact cttccactta aaagaaatga acagtctttc
     1021 ttggctgtgc cccaagcagt ttgtcagtag gtgcagaact ccatgaacac aacattaaaa
     1081 ggaataccac attaaaattg atgatgggag cctagcctta gggagtaaat ggtgttttga
     1141 aaatgaatag tatttgaaat taaatcaggt tttgttgata tcccaattgt gaagaactta
     1201 gcgcccccat gcagcgcccc ttgcttggca ggacctggga agcccgtgct cctttgcaaa
     1261 gctgtgttta ggcaataaag aggtcagaag tttaaaaaaa aaaaaaaaaa
//
