LOCUS       NM_025619               1675 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus cilia and flagella associated protein 157 (Cfap157),
            mRNA.
ACCESSION   NM_025619 XM_484987 XM_915094 XM_991441
VERSION     NM_025619.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Weidemann,M., Schuster-Gossler,K., Stauber,M., Wrede,C.,
            Hegermann,J., Ott,T., Boldt,K., Beyer,T., Serth,K., Kremmer,E.,
            Blum,M., Ueffing,M. and Gossler,A.
  TITLE     CFAP157 is a murine downstream effector of FOXJ1 that is
            specifically required for flagellum morphogenesis and sperm
            motility
  JOURNAL   Development 143 (24), 4736-4748 (2016)
   PUBMED   27965440
  REMARK    GeneRIF: Cfap157-deficient sperm exhibit axonemal loops,
            supernumerary axonemal profiles with ectopic accessory structures,
            excess cytoplasm and clustered mitochondria in the midpiece
            regions, and defective axonemes along the flagella.
REFERENCE   2  (bases 1 to 1675)
  AUTHORS   Xiao,C., Calado,D.P., Galler,G., Thai,T.H., Patterson,H.C.,
            Wang,J., Rajewsky,N., Bender,T.P. and Rajewsky,K.
  TITLE     MiR-150 Controls B Cell Differentiation by Targeting the
            Transcription Factor c-Myb
  JOURNAL   Cell 165 (4), 1027 (2016)
   PUBMED   27153500
  REMARK    Correction to:[Cell. 2007 Oct 5;131(1):146-59. doi:
            10.1016/j.cell.2007.07.021.. PMID: 17923094]
REFERENCE   3  (bases 1 to 1675)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: 1700019L03Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC118617.1.
            
            On or before Sep 4, 2006 this sequence version replaced
            XM_915094.2, XM_484987.3, XM_991441.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC118617.1, AK006127.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.09 cM"
     gene            1..1675
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /note="cilia and flagella associated protein 157"
                     /db_xref="GeneID:227736"
                     /db_xref="MGI:MGI:2447809"
     exon            1..185
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..1590
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 157"
                     /protein_id="NP_079895.1"
                     /db_xref="CCDS:CCDS15932.1"
                     /db_xref="GeneID:227736"
                     /db_xref="MGI:MGI:2447809"
                     /translation="MAPKKKPNKGGKEMQGKKIGGKKDASGTKTPELAMVEELKEFYH
                     KQIQDLEDRLARYQRKWDELAVREKLFHQEFEQLANNKKEIVAFLKRTLNQKVDEITD
                     LNDQLQSLEVAKDMEKDAFEAQLAQVRHEFQEIKDQLTTENIALGIKLSSLEEFRLQK
                     EELTEKYLALEEQLHRQEGEYKEYVYNLEKKSVLDKDRLRKEIIQRVNLVATEFRKMA
                     TNQMWETTRRAILENNSVTLQLNKVSKHGVQLLQENEQLKGTQNKLCQQLEMLENTQE
                     IMARKNIGHKKIILMLTEKCRQQRKGTEETEQLRLLLSQLEQNFQNVQRDNQTLRSEK
                     DQLEAQLKEKQAEANRLQEELTKEQKIRANLKTVLIQATSMLQDIVHMQTEAEDGDFD
                     VVFQLQRKELLQQLLVLLSSGVVLKTQPDMGSHQDKQPQGLSKESQRITQTSKEGAVS
                     LLQQLSTITTYKPGDLGLVPRRPVRIPLKPQDLRPLSYITRMGICQNTNEIYPSGALK
                     RFRKFTLPRPFLHRK"
     exon            186..457
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            458..611
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            612..879
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1010
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1161
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1328
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1518
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1675
                     /gene="Cfap157"
                     /gene_synonym="1700019L03Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagtggttgc catcagccat ggctccaaaa aagaagccaa acaaaggagg caaggagatg
       61 cagggcaaga agataggggg caagaaggat gccagtggga ccaagactcc agagttggcc
      121 atggtggagg agctgaagga attctaccac aaacagatcc aagacctgga ggacaggctg
      181 gcccggtatc agcggaaatg ggatgaactg gctgtgcggg agaagctgtt ccatcaggag
      241 ttcgagcagc tggccaacaa caagaaggag attgtggcct tcctcaagcg cacgctgaac
      301 cagaaggtgg atgagatcac agaccttaat gaccagctgc agagcctgga ggtggccaag
      361 gatatggaga aggacgcgtt cgaggcccaa ctggcccagg tgcgccatga attccaggaa
      421 atcaaggacc agctcaccac agagaacatc gccctcggga tcaagctgag ttccctggaa
      481 gaattccggc tgcagaaaga ggagctcacg gagaagtact tggcactgga ggagcagctc
      541 cataggcagg agggcgagta caaggaatac gtgtacaacc tggagaagaa gtctgtgctg
      601 gacaaggaca ggctgaggaa agagattatc cagcgtgtga acctggtggc cacagagttc
      661 cgaaagatgg ccaccaacca gatgtgggag acgaccaggc gggccatcct agagaacaac
      721 agcgtgactc tgcagctaaa caaggtgtcc aagcatggtg tgcagctgct gcaggagaat
      781 gagcagctca agggcaccca gaacaagctg tgccaacagc tggagatgct ggagaacacc
      841 caagagatca tggccagaaa gaacataggg cataagaaga ttatcctcat gctgaccgag
      901 aagtgccgcc aacagagaaa gggcacagag gagacggagc aactgcgcct cctgctgtcc
      961 caactggagc agaacttcca gaatgtgcag agggacaacc agaccctgag gagtgagaaa
     1021 gaccagctgg aagcgcaact gaaggagaag caggcagagg caaatcggct acaggaggag
     1081 ctgaccaagg aacagaaaat tcgggcaaac cttaaaacag tcctgatcca ggcgacctcc
     1141 atgctacagg acattgtgca catgcaaaca gaggcggagg acggcgactt tgatgtggtg
     1201 ttccaactgc agcgcaagga gctgctgcag caactgctgg tattgctcag ctcaggggtg
     1261 gttttgaaaa cacagccgga catgggttcc caccaggaca agcagcccca gggcctatcc
     1321 aaagaaagcc aacgcatcac ccagacatcc aaggaagggg ctgtttctct gctgcagcag
     1381 ctctcgacca tcacaaccta taagccaggg gatcttgggc tggtgcctcg acgtccggtc
     1441 cgcatcccac tcaaacccca ggatctcagg cccctctcct atatcacccg aatggggatc
     1501 tgccagaaca cgaatgagat ctacccatct ggagctctca aaaggttcag aaagtttacc
     1561 cttcctagac ctttcctaca ccgcaaatag cgaacgggga gaccaagctg ctgcagaaac
     1621 agactgatgt ggccacagtc cctccttgaa tctgcaagta gcctggggaa accca
//
