LOCUS       NM_001033040            1121 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus cilia and flagella associated protein 119 (Cfap119),
            transcript variant 1, mRNA.
ACCESSION   NM_001033040
VERSION     NM_001033040.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Zhou,H., Yang,F., Li,G., Yuan,L., Ge,T., Niu,C. and Zheng,Y.
  TITLE     CCDC189 depletion leads to oligo-astheno-teratozoospermia and male
            infertility in micedagger
  JOURNAL   Biol Reprod 111 (4), 800-814 (2024)
   PUBMED   39018224
  REMARK    GeneRIF: CCDC189 depletion leads to oligo-astheno-teratozoospermia
            and male infertility in micedagger.
REFERENCE   2  (bases 1 to 1121)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1121)
  AUTHORS   Wang,M., Kang,J., Shen,Z., Hu,Y., Chen,M., Cui,X., Liu,H. and
            Gao,F.
  TITLE     CCDC189 affects sperm flagellum formation by interacting with
            CABCOCO1
  JOURNAL   Natl Sci Rev 10 (9), nwad181 (2023)
   PUBMED   37601242
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1121)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122417.4.
            
            On Apr 7, 2022 this sequence version replaced NM_001033040.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066021.1, AK140121.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-282               AC122417.4         138418-138699       c
            283-314             AC122417.4         138105-138136       c
            315-380             AC122417.4         137364-137429       c
            381-550             AC122417.4         136816-136985       c
            551-621             AC122417.4         135995-136065       c
            622-738             AC122417.4         135686-135802       c
            739-799             AC122417.4         135534-135594       c
            800-892             AC122417.4         135362-135454       c
            893-1121            AC122417.4         133902-134130       c
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.61 cM"
     gene            1..1121
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /note="cilia and flagella associated protein 119"
                     /db_xref="GeneID:233899"
                     /db_xref="MGI:MGI:2685012"
     exon            1..282
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            283..314
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            315..380
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            381..550
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            551..621
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            622..738
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            739..799
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            800..892
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1121
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1088..1093
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /note="hexamer: AATAAA"
     polyA_site      1121
                     /gene="Cfap119"
                     /gene_synonym="Ccdc189; Gm166"
                     /note="major polyA site"
ORIGIN      
        1 agtgggagag ctggctgtcc cagagcccag gctggagagc ccttgactga ggctaagaag
       61 gacgaagaga tgattacccc cagttccagc cagagcctgg gaatgaaggt gcagatggag
      121 tcggaacaat ctcccaaatt gcaggaggaa ctggacagga gtcccagctc ggtggacggc
      181 tcggccataa ggaacggaac agacatgcag accgagtcgc ccgcagaagc cactagtagc
      241 cctgtggaag tggctgaaga tcctggagcc aacttgttcc cgccaccact accccagccc
      301 cggatctgta tgtggaaata cctggacatc cattctatgc acagactgga gaaggcagcc
      361 actgtggaaa agatgagaga ggttcttgct gagctcttgg agcttggctt tcctgagcag
      421 agcctgcggg atgccattat cttggacctc ttctcccacg cacttatctt ctgccgccag
      481 cagggctttt caccagagca gacatcagca gcctgtgcca tgctccaaga tcttcacaag
      541 gcctgtgttg ctacccctct gggcaacgtg gaggaatgct accgctactt taccagcgtt
      601 ctcttttgtc atggaatcag gcggccccct ttcagcattg acctctttaa agaggaacag
      661 ctgctggcac tggcagacta tgtggtcaac acctacttcc gccacttcaa gctctacaaa
      721 tatgtcttca ccccacaggt gcgactggac ctatctttga cttacacggg gttacagcca
      781 ctcacgctct ggccagagga gaaagaaaac gaggagatga tggtggtaga gcaagtagct
      841 actccacagg aggaagagcc ggaaactgtg acggagccag agcaacagcc aagtgaggtg
      901 tgcatcctcc agacctacat caagtcccag ctgagcaagg agctgaggca gctccagcag
      961 ctggtggagg agcggctcaa ggagagcgag gaaaggctga gcagcaaact ggctgcactg
     1021 gagcagccgt tccagacacc tcccagcaaa ggcaagacca agaccaagtg atcccagcat
     1081 cttccccaat aaagacctgg gccacagtgt cccatccccc a
//
