LOCUS       NM_145825               1059 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus centrin 4 (Cetn4), mRNA.
ACCESSION   NM_145825 XM_913564
VERSION     NM_145825.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Trojan,P., Rausch,S., Giessl,A., Klemm,C., Krause,E.,
            Pulvermuller,A. and Wolfrum,U.
  TITLE     Light-dependent CK2-mediated phosphorylation of centrins regulates
            complex formation with visual G-protein
  JOURNAL   Biochim Biophys Acta 1783 (6), 1248-1260 (2008)
   PUBMED   18269917
REFERENCE   2  (bases 1 to 1059)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Cetn4 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
REFERENCE   3  (bases 1 to 1059)
  AUTHORS   Giessl,A., Pulvermuller,A., Trojan,P., Park,J.H., Choe,H.W.,
            Ernst,O.P., Hofmann,K.P. and Wolfrum,U.
  TITLE     Differential expression and interaction with the visual G-protein
            transducin of centrin isoforms in mammalian photoreceptor cells
  JOURNAL   J Biol Chem 279 (49), 51472-51481 (2004)
   PUBMED   15347651
  REMARK    GeneRIF: Binding of Cen2 and Cen4 to Gbetagamma of non-visual
            G-proteins regulates G-proteins involved in centrosome and basal
            body functions
REFERENCE   4  (bases 1 to 1059)
  AUTHORS   Gavet,O., Alvarez,C., Gaspar,P. and Bornens,M.
  TITLE     Centrin4p, a novel mammalian centrin specifically expressed in
            ciliated cells
  JOURNAL   Mol Biol Cell 14 (5), 1818-1834 (2003)
   PUBMED   12802058
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL691478.5.
            
            On Mar 21, 2007 this sequence version replaced NM_145825.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF362367.1, BC060991.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                AL691478.5         70483-70572         c
            91-237              AL691478.5         68419-68565         c
            238-366             AL691478.5         68063-68191         c
            367-504             AL691478.5         67471-67608         c
            505-1059            AL691478.5         66753-67307         c
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 18.41 cM"
     gene            1..1059
                     /gene="Cetn4"
                     /note="centrin 4"
                     /db_xref="GeneID:207175"
                     /db_xref="MGI:MGI:2677454"
     exon            1..90
                     /gene="Cetn4"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..594
                     /gene="Cetn4"
                     /note="centrin4"
                     /codon_start=1
                     /product="centrin-4"
                     /protein_id="NP_665824.1"
                     /db_xref="CCDS:CCDS17318.1"
                     /db_xref="GeneID:207175"
                     /db_xref="MGI:MGI:2677454"
                     /translation="MASSQRITLDQWKKKAAKVELNDTQKQEIKEAFDLFDIDGSGTI
                     DLKELKIAMRALGFEPKKEEVKQLIAEIDKEGTGTICFEDFFAIMSVKMSEKDEKEEI
                     LKAFKLFDDDATGSISLNNIKRVAKELGENLTEDELQEMLDEADRDGDGEINEEEFLK
                     MMKKTSLY"
     exon            91..237
                     /gene="Cetn4"
                     /inference="alignment:Splign:2.1.0"
     exon            238..366
                     /gene="Cetn4"
                     /inference="alignment:Splign:2.1.0"
     exon            367..504
                     /gene="Cetn4"
                     /inference="alignment:Splign:2.1.0"
     exon            505..1059
                     /gene="Cetn4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1039..1044
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn4"
                     /note="hexamer: AATAAA"
     polyA_site      1059
                     /gene="Cetn4"
                     /note="major polyA site"
ORIGIN      
        1 atagcaaccg cctgtcggga gcaaacgcgg gccgcggagg ggagagcggc tgttgcgcgg
       61 gcgcgggcag gggcgcaggg aggggatatg gcatccagcc agcgcataac tttagaccaa
      121 tggaagaaaa aagcagcaaa agttgaactg aatgacaccc agaagcaaga aattaaagag
      181 gcctttgact tattcgatat tgatggatct ggaaccatag atctgaaaga actgaagatt
      241 gcaatgaggg ccttaggctt tgagccaaag aaagaagaag taaaacaact gatcgctgaa
      301 atcgacaagg aagggactgg caccatttgt tttgaagatt tttttgccat catgagcgta
      361 aaaatgagtg aaaaagatga aaaagaagaa atactgaagg catttaaatt atttgatgac
      421 gatgctacgg gaagcatatc actaaataac atcaagaggg ttgccaagga gctaggggaa
      481 aacttaaccg aagatgaatt acaggaaatg cttgatgaag ctgatcgtga cggggatgga
      541 gagattaatg aggaagaatt cttgaagatg atgaagaaga ccagccttta ttagctgctt
      601 ggtgccttcc aagaggtttg gacctcctgt taacagcttt cctgttaagc agttcaatga
      661 tgtaatacct gagtgtatcc atttccacgt ttagtttagg ttagtccctt ggtgtctaat
      721 ctgtgccaga agttatatgt ccctaccaat gtcattaaat ctgtagtagt aagaaacaaa
      781 cagacaaaca aaagcatgat ttatttgaac tgtgagcccc aaaacagtat ttccatatgg
      841 tattttaaag tcatagattc caaagacatt tgacttttat ttttcagttg aataaacttg
      901 gcccccagat ccagatgaaa ttgtttttaa aaacaatctg aaaatggtat ttttccatta
      961 tttcctttta tatgacttaa aaaacacctg ataaacatgt tctttttaaa aatctgttcc
     1021 ttcaatatgt aaagtattaa taaaactagc tgacataca
//
