LOCUS       NM_007684               1070 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus centrin 3 (Cetn3), mRNA.
ACCESSION   NM_007684
VERSION     NM_007684.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Allon,G., Mann,I., Remez,L., Sehn,E., Rizel,L., Nevet,M.J.,
            Perlman,I., Wolfrum,U. and Ben-Yosef,T.
  TITLE     PRCD is concentrated at the base of photoreceptor outer segments
            and is involved in outer segment disc formation
  JOURNAL   Hum Mol Genet 28 (24), 4078-4088 (2019)
   PUBMED   31628458
REFERENCE   2  (bases 1 to 1070)
  AUTHORS   Ying,G., Frederick,J.M. and Baehr,W.
  TITLE     Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the
            distal connecting cilium of mouse photoreceptors
  JOURNAL   J Biol Chem 294 (11), 3957-3973 (2019)
   PUBMED   30647131
  REMARK    GeneRIF: Removal of CETN2 and CETN3 activity from the lumen of the
            connecting cilium (CC) destabilized the photoreceptor axoneme and
            reduced the CC length as early as postnatal day 22 (P22).
REFERENCE   3  (bases 1 to 1070)
  AUTHORS   Marjanovic,M., Sanchez-Huertas,C., Terre,B., Gomez,R., Scheel,J.F.,
            Pacheco,S., Knobel,P.A., Martinez-Marchal,A., Aivio,S.,
            Palenzuela,L., Wolfrum,U., McKinnon,P.J., Suja,J.A., Roig,I.,
            Costanzo,V., Luders,J. and Stracker,T.H.
  TITLE     CEP63 deficiency promotes p53-dependent microcephaly and reveals a
            role for the centrosome in meiotic recombination
  JOURNAL   Nat Commun 6, 7676 (2015)
   PUBMED   26158450
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1070)
  AUTHORS   Karlstetter,M., Sorusch,N., Caramoy,A., Dannhausen,K.,
            Aslanidis,A., Fauser,S., Boesl,M.R., Nagel-Wolfrum,K., Tamm,E.R.,
            Jagle,H., Stoehr,H., Wolfrum,U. and Langmann,T.
  TITLE     Disruption of the retinitis pigmentosa 28 gene Fam161a in mice
            affects photoreceptor ciliary structure and leads to progressive
            retinal degeneration
  JOURNAL   Hum Mol Genet 23 (19), 5197-5210 (2014)
   PUBMED   24833722
REFERENCE   5  (bases 1 to 1070)
  AUTHORS   Muhlhans,J., Brandstatter,J.H. and Giessl,A.
  TITLE     The centrosomal protein pericentrin identified at the basal body
            complex of the connecting cilium in mouse photoreceptors
  JOURNAL   PLoS One 6 (10), e26496 (2011)
   PUBMED   22031837
REFERENCE   6  (bases 1 to 1070)
  AUTHORS   Trojan,P., Rausch,S., Giessl,A., Klemm,C., Krause,E.,
            Pulvermuller,A. and Wolfrum,U.
  TITLE     Light-dependent CK2-mediated phosphorylation of centrins regulates
            complex formation with visual G-protein
  JOURNAL   Biochim Biophys Acta 1783 (6), 1248-1260 (2008)
   PUBMED   18269917
REFERENCE   7  (bases 1 to 1070)
  AUTHORS   Giessl,A., Pulvermuller,A., Trojan,P., Park,J.H., Choe,H.W.,
            Ernst,O.P., Hofmann,K.P. and Wolfrum,U.
  TITLE     Differential expression and interaction with the visual G-protein
            transducin of centrin isoforms in mammalian photoreceptor cells
  JOURNAL   J Biol Chem 279 (49), 51472-51481 (2004)
   PUBMED   15347651
REFERENCE   8  (bases 1 to 1070)
  AUTHORS   Funatsu,N., Inoue,T. and Nakamura,S.
  TITLE     Gene expression analysis of the late embryonic mouse cerebral
            cortex using DNA microarray: identification of several region- and
            layer-specific genes
  JOURNAL   Cereb Cortex 14 (9), 1031-1044 (2004)
   PUBMED   15142957
REFERENCE   9  (bases 1 to 1070)
  AUTHORS   Gavet,O., Alvarez,C., Gaspar,P. and Bornens,M.
  TITLE     Centrin4p, a novel mammalian centrin specifically expressed in
            ciliated cells
  JOURNAL   Mol Biol Cell 14 (5), 1818-1834 (2003)
   PUBMED   12802058
REFERENCE   10 (bases 1 to 1070)
  AUTHORS   Middendorp,S., Paoletti,A., Schiebel,E. and Bornens,M.
  TITLE     Identification of a new mammalian centrin gene, more closely
            related to Saccharomyces cerevisiae CDC31 gene
  JOURNAL   Proc Natl Acad Sci U S A 94 (17), 9141-9146 (1997)
   PUBMED   9256449
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY103593.1, AK006891.1 and AI851499.1.
            
            On Feb 27, 2018 this sequence version replaced NM_007684.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006891.1, SRR1660819.176950.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                BY103593.1         3-47
            46-993              AK006891.1         1-948
            994-1070            AI851499.1         1-77                c
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 43.68 cM"
     gene            1..1070
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /note="centrin 3"
                     /db_xref="GeneID:12626"
                     /db_xref="MGI:MGI:1097706"
     exon            1..111
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /inference="alignment:Splign:2.1.0"
     exon            112..247
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /inference="alignment:Splign:2.1.0"
     exon            248..362
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /inference="alignment:Splign:2.1.0"
     exon            363..554
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /inference="alignment:Splign:2.1.0"
     exon            555..1056
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      799..804
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /note="hexamer: TATAAA"
     polyA_site      820
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /note="major polyA site"
     regulatory      912..917
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /note="hexamer: AATAAA"
     polyA_site      935
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
     regulatory      1037..1042
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
                     /note="hexamer: AATAAA"
     polyA_site      1056
                     /gene="Cetn3"
                     /gene_synonym="MmCEN3"
ORIGIN      
        1 tctggtgggt ggtccccgag gcgtggaggt tggtggctgt tgagcggttc ccgtggtaaa
       61 gtccccgagt ggaacatctc tgtcggaaga gagaatgagt ttagctctga gaggtgagct
      121 tgtagtagac aaaacaaaaa ggaaaaaacg aagagagctc tctgaagaac agaagcaaga
      181 aattaaagat gcttttgagc tgtttgatac cgacaaagac caagccatag attatcatga
      241 attaaaggtg gcaatgagag ccttgggctt tgatgtgaaa aaggctgatg tgttgaagat
      301 tcttaaagat tatgacagag aagccactgg caagatcaca tttgaagatt ttaatgaagt
      361 tgtgacagac tggatactag agagagatcc acatgaggag atactgaaag catttaaact
      421 atttgacgat gacgattcag gaaagataag cttgaggaat ttacggcgtg ttgccagaga
      481 gctgggtgag aacatgagcg atgaggagct ccgggccatg atagaggagt ttgacaaaga
      541 cggcgatgga gagataaatc aagaggaatt cattgctatt atgactggtg acatataaag
      601 aatcaacacc aaaatgttac ttttaccatc tatcttctct ttgtgtgcct ggagtccagt
      661 ttaagaaaac gaaacaaaac aaacgtagtt ctttttctga aaggaacaaa accaagcatc
      721 ctttgtatgt atatttcagc attgttaagt ttatgtcatc aatgtagtag ttgacttcac
      781 atttataata catgtttata taaagtttta aaacatcaaa tcatgtggtg tatgttattt
      841 ggagtcttct aaatttagga ctagctaatt gcttttattt tcatgcacat gttttttttt
      901 tgacattcat taataaaata cttattttat tagtatgtta atgtttggta aattttttat
      961 ttcagatttc tgatatctat taacaataga agatttttaa aaatcttttg tctttacact
     1021 ttcacttgta tttgaaaata aatcagaaaa accaaaaaaa aaaaaaaaaa
//
