LOCUS       NM_019405               1237 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus centrin 2 (Cetn2), mRNA.
ACCESSION   NM_019405
VERSION     NM_019405.7
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Jiang,X., Cheng,Y., Zhu,Y., Xu,C., Li,Q., Xing,X., Li,W., Zou,J.,
            Meng,L., Azhar,M., Cao,Y., Tong,X., Qin,W., Zhu,X. and Bao,J.
  TITLE     Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression
            and maturation in mice
  JOURNAL   Nat Commun 14 (1), 3729 (2023)
   PUBMED   37349316
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  AUTHORS   He,S., Gillies,J.P., Zang,J.L., Cordoba-Beldad,C.M., Yamamoto,I.,
            Fujiwara,Y., Grantham,J., DeSantis,M.E. and Shibuya,H.
  TITLE     Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate
            mitotic and male meiotic spindle bipolarity
  JOURNAL   Nat Commun 14 (1), 1715 (2023)
   PUBMED   36973253
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1237)
  AUTHORS   Mercey,O., Levine,M.S., LoMastro,G.M., Rostaing,P., Brotslaw,E.,
            Gomez,V., Kumar,A., Spassky,N., Mitchell,B.J., Meunier,A. and
            Holland,A.J.
  TITLE     Massive centriole production can occur in the absence of
            deuterosomes in multiciliated cells
  JOURNAL   Nat Cell Biol 21 (12), 1544-1552 (2019)
   PUBMED   31792378
REFERENCE   4  (bases 1 to 1237)
  AUTHORS   Ying,G., Frederick,J.M. and Baehr,W.
  TITLE     Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the
            distal connecting cilium of mouse photoreceptors
  JOURNAL   J Biol Chem 294 (11), 3957-3973 (2019)
   PUBMED   30647131
  REMARK    GeneRIF: Removal of CETN2 and CETN3 activity from the lumen of the
            connecting cilium (CC) destabilized the photoreceptor axoneme and
            reduced the CC length as early as postnatal day 22 (P22).
REFERENCE   5  (bases 1 to 1237)
  AUTHORS   Mahuzier,A., Shihavuddin,A., Fournier,C., Lansade,P., Faucourt,M.,
            Menezes,N., Meunier,A., Garfa-Traore,M., Carlier,M.F.,
            Voituriez,R., Genovesio,A., Spassky,N. and Delgehyr,N.
  TITLE     Ependymal cilia beating induces an actin network to protect
            centrioles against shear stress
  JOURNAL   Nat Commun 9 (1), 2279 (2018)
   PUBMED   29891944
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1237)
  AUTHORS   Hart,P.E., Glantz,J.N., Orth,J.D., Poynter,G.M. and Salisbury,J.L.
  TITLE     Testis-specific murine centrin, Cetn1: genomic characterization and
            evidence for retroposition of a gene encoding a centrosome protein
  JOURNAL   Genomics 60 (2), 111-120 (1999)
   PUBMED   10486202
REFERENCE   7  (bases 1 to 1237)
  AUTHORS   LeDizet,M., Beck,J.C. and Finkbeiner,W.E.
  TITLE     Differential regulation of centrin genes during ciliogenesis in
            human tracheal epithelial cells
  JOURNAL   Am J Physiol 275 (6), L1145-L1156 (1998)
   PUBMED   9843852
REFERENCE   8  (bases 1 to 1237)
  AUTHORS   Kuroiwa,A., Watanabe,T., Hishigaki,H., Takahashi,E., Namikawa,T.
            and Matsuda,Y.
  TITLE     Comparative FISH mapping of mouse and rat homologues of twenty-five
            human X-linked genes
  JOURNAL   Cytogenet Cell Genet 81 (3-4), 208-212 (1998)
   PUBMED   9730605
REFERENCE   9  (bases 1 to 1237)
  AUTHORS   Chatterjee,A., Tanaka,T., Parrish,J.E. and Herman,G.E.
  TITLE     Refined mapping of caltractin in human Xq28 and in the homologous
            region of the mouse X chromosome places the gene within the bare
            patches (Bpa) and striated (Str) critical regions
  JOURNAL   Mamm Genome 6 (11), 802-804 (1995)
   PUBMED   8597638
REFERENCE   10 (bases 1 to 1237)
  AUTHORS   Ogawa,K. and Shimizu,T.
  TITLE     cDNA sequence for mouse caltractin
  JOURNAL   Biochim Biophys Acta 1216 (1), 126-128 (1993)
   PUBMED   8218402
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671908.8.
            
            On Jan 28, 2022 this sequence version replaced NM_019405.6.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140156.1, AK004081.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                AL671908.8         143600-143647       c
            49-207              AL671908.8         141974-142132       c
            208-336             AL671908.8         141551-141679       c
            337-474             AL671908.8         140126-140263       c
            475-1237            AL671908.8         138817-139579       c
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.29 cM"
     gene            1..1237
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /note="centrin 2"
                     /db_xref="GeneID:26370"
                     /db_xref="MGI:MGI:1347085"
     exon            1..48
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /inference="alignment:Splign:2.1.0"
     exon            49..207
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /inference="alignment:Splign:2.1.0"
     exon            208..336
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /inference="alignment:Splign:2.1.0"
     exon            337..474
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /inference="alignment:Splign:2.1.0"
     exon            475..1237
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1043..1048
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /note="hexamer: AATAAA"
     polyA_site      1064
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /note="major polyA site"
     regulatory      1178..1183
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /note="hexamer: ATTAAA"
     polyA_site      1205
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
     regulatory      1215..1220
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
                     /note="hexamer: CATAAA"
     polyA_site      1237
                     /gene="Cetn2"
                     /gene_synonym="1110034A02Rik; Calt; caltractin"
ORIGIN      
        1 gagtacgccg ttgccttaac aaccggtggc agagtccgtt gggtgatggc ctctaatttt
       61 aagaagacaa ccatggcatc cagtgcccag agaaaaagga tgagtcctaa gcctgaactt
      121 actgaagacc agaaacagga aatccgggaa gcttttgatc tctttgatgc tgatggaact
      181 ggaactatag acatcaaaga actgaaggtg gcaatgaggg ccctgggctt tgagcccaag
      241 aaagaagaaa ttaagaaaat gataagtgaa attgataaag aaggaacagg aaaaatgaac
      301 ttcagtgact ttttgacagt gatgactcag aaaatgtctg agaaagacac taaagaagaa
      361 atcctgaaag ctttcaagtt gttcgatgat gatgagactg ggaaaatatc attcaagaat
      421 cttaagcgcg tggccaagga gctgggtgag aacctgacag atgaggaact gcaggaaatg
      481 attgatgaag ctgatcgaga tggagatggt gaggtcaatg agcaagagtt cctgcgcatc
      541 atgaaaaaga ccagcctcta ttaagatcag tgtttctttt tctactgcaa gcacatgtga
      601 ctagatttag tgcctggcat tttgtgaaat atggcttttg aaagcctccc tcccccaacc
      661 tggggtaact ttagccatga ccttgaatct atttttgact tttggaagtg ttctttgata
      721 ttaagttctt tgtacattta cctgctgact aaatcaacag ggcagaacaa gagcacatag
      781 agtggggaaa agggtctgaa agtgtgactg tggccacccc accttccatt acttcacctt
      841 gctcatgcat atccactcga ctgaaaacat gcagtggctt cttagttgtc catgtatcca
      901 tgtcaccata agcagtggtt gttcttaaag tggttttggt tttcatttga caccacagta
      961 cagttttctc ttttacaaaa cccaatgagt gcttgctgtg gcatttggat gtgtgttaat
     1021 gtatttgttt ggtctttaaa aaaataaaac ctttcttaat ttaagctctc attctttaaa
     1081 ggatgagtat tttttagctt taactgtgag ttcaccttgt aaacaactgt gttgaggaca
     1141 gcctggtaca tatatacaat ttgtcatcgg cctatggatt aaaaaagggt aataattctt
     1201 tgtaactttt ctgccataaa tagttttttt gctttca
//
