LOCUS       NM_001079865            1823 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus carboxylesterase 2F (Ces2f), transcript variant 1,
            mRNA.
ACCESSION   NM_001079865 XM_146486 XM_914996 XM_994250
VERSION     NM_001079865.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1823)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1823)
  AUTHORS   Holmes,R.S., Wright,M.W., Laulederkind,S.J., Cox,L.A., Hosokawa,M.,
            Imai,T., Ishibashi,S., Lehner,R., Miyazaki,M., Perkins,E.J.,
            Potter,P.M., Redinbo,M.R., Robert,J., Satoh,T., Yamashita,T.,
            Yan,B., Yokoi,T., Zechner,R. and Maltais,L.J.
  TITLE     Recommended nomenclature for five mammalian carboxylesterase gene
            families: human, mouse, and rat genes and proteins
  JOURNAL   Mamm Genome 21 (9-10), 427-441 (2010)
   PUBMED   20931200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC117742.1.
            
            On Dec 31, 2006 this sequence version replaced NM_001079865.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC117742.1, AK040349.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1823
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.04 cM"
     gene            1..1823
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /note="carboxylesterase 2F"
                     /db_xref="GeneID:71903"
                     /db_xref="MGI:MGI:1919153"
     exon            1..99
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..1709
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /product="carboxylesterase 2F isoform 1 precursor"
                     /protein_id="NP_001073334.2"
                     /db_xref="CCDS:CCDS40453.1"
                     /db_xref="GeneID:71903"
                     /db_xref="MGI:MGI:1919153"
                     /translation="MPVHRLPGWLDAAACGLLVLLLHVKGLDSSEASPIRNTHTGQVR
                     GKFVHLTDIKAGAHNFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNDD
                     IVNLEGLKIIKMILPPFSMSEDCLYLNIYTPAHAQEGSNLPVMVWLHGGGLVAGMASM
                     YDGSVLAATEDVVVVVTQYRLGIPGFYSTGDEQARGNWGFLDQTAALHWVQQNIANFG
                     GNPDSVTLFGQSAGGTSVSFHVLSPVSQGLFHRAIMESGVALLPTIIPDSPEMIFTKV
                     ANLSGCETSNSEALVRCLRGKSEAEILAMSKAFRFMPAVVDGKFLPRHPKKLLASADF
                     HPVPSIIGVNNDEYGWIIPKIFKFSQTIRKINRNNLKAIMKITTEQMMLPSECGDLLI
                     EEYLRDTEDPWTLQMQFREMIGDFLIIIPALQVARFQRSHAPVYFYEFQHRSSLLKYF
                     RPWHVKADHGDELYLIFGSFFWGLKFSFTAEEKLLSRKMMKYWANFARYGNPNSEDLP
                     YWPASNQDDLYLQLDIHPSVGHALKARRLPFWTKTLPQKMLELKGNHDKIKAV"
     exon            100..310
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            311..452
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            453..586
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            587..845
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            846..944
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1085
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1166
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1311
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1449
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1522
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1721
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1823
                     /gene="Ces2f"
                     /gene_synonym="2310038E17Rik; A430088E12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agattcaggc ctgggagccg atcatgccag tgcacagact tcctggatgg ctggatgctg
       61 cggcctgtgg gctcctggtt ctcctcctcc atgtgaaggg tcttgactca tcagaggcca
      121 gccccatcag aaacacacat actggacagg tccgaggcaa gtttgtccac ttgacagaca
      181 tcaaagctgg agcccataac ttcctgggga tcccctttgc caagcctcct gtaggaccac
      241 tgcgctttgc acctcctgag gcccctgagc catggagtgg tgtgagagat gggacctcac
      301 agccggccat gtgtctacaa aatgatgata tagtgaattt agagggtctg aagataataa
      361 agatgatcct gcctcccttc tctatgtctg aggactgcct gtatctcaac atctacacac
      421 cagcccacgc ccaggagggc tctaacctgc ctgtgatggt gtggctccat ggtggtggac
      481 tggttgcagg catggcttcc atgtatgatg gatccgtgct ggcagccact gaggatgtgg
      541 tggtggtggt tactcagtac cgcctgggaa tcccgggctt ttacagcact ggagatgagc
      601 aggccagagg caactgggga ttcttagacc aaacagctgc cctacactgg gtccagcaga
      661 acattgccaa ctttggaggc aaccctgatt ctgtcacact ttttggccag tcagcaggtg
      721 gcacaagtgt gtctttccat gtcttgtccc ccgtgtccca aggactcttc catagagcca
      781 tcatggagag tggggtggcc ctgctgccta ccattatacc tgactcccct gagatgatct
      841 tcacaaaggt ggcaaaccta tctggttgtg aaacttcaaa ctcagaagcc ctggtgcgct
      901 gccttcgagg caagagtgaa gcagaaattc tggctatgag caaggccttc aggtttatgc
      961 ctgctgtggt ggatgggaaa ttcctaccca gacatcccaa gaagttgctg gcctctgctg
     1021 actttcaccc tgtccccagc attattggtg tcaacaatga tgagtatggc tggattatcc
     1081 ctaagatctt caaattttct cagacaataa ggaaaataaa tagaaataac ttgaaggcta
     1141 ttatgaagat cacaacagag caaatgatgc tgccttctga gtgtggtgac ctgctaatag
     1201 aagagtactt aagagacact gaggacccct ggacactcca aatgcagttc agagagatga
     1261 taggggactt cttaattata atccctgcac tccaagtagc acgttttcag cgttcccatg
     1321 ctcctgtcta cttctatgag ttccagcata ggtccagttt actcaagtat ttcaggccat
     1381 ggcatgttaa ggctgaccac ggtgatgagc tttaccttat ctttggatcc ttcttctggg
     1441 gcctcaaatt tagcttcact gcggaggaga agctgctgag caggaagatg atgaaatact
     1501 gggccaactt tgcacgatat gggaacccca acagtgagga tctaccctac tggccagcgt
     1561 caaaccaaga tgatctgtac ctgcagctgg acatccaccc ttctgtgggc catgccctga
     1621 aggccagaag gctgccattc tggaccaaga ctcttcccca gaagatgcta gagctaaaag
     1681 gaaatcacga taaaatcaag gctgtatagt gcccaggaaa gggtgtttgt agacactatg
     1741 acactcacac ctgcatgaac atctaacatc tgtgaagatc ttttgctatt gtgtgtcaca
     1801 tgggtgtaaa gtagagaagg tag
//
