LOCUS       NM_001370830            1925 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus carboxylesterase 1H (Ces1h), mRNA.
ACCESSION   NM_001370830 XM_017313042
VERSION     NM_001370830.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Holmes RS, Wright MW, Laulederkind SJ, Cox LA, Hosokawa M, Imai T,
            Ishibashi S, Lehner R, Miyazaki M, Perkins EJ, Potter PM, Redinbo
            MR, Robert J, Satoh T, Yamashita T, Yan B, Yokoi T, Zechner R and
            Maltais LJ.
  TITLE     Recommended nomenclature for five mammalian carboxylesterase gene
            families: human, mouse, and rat genes and proteins
  JOURNAL   Mamm Genome 21 (9-10), 427-441 (2010)
   PUBMED   20931200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC162945.6 and AC162949.7.
            
            On Jun 5, 2019 this sequence version replaced XM_017313042.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN00849387 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            inferred exon combination        :: based on alignments, homology
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               AC162945.6         85582-85682         c
            102-309             AC162945.6         80314-80521         c
            310-457             AC162945.6         78423-78570         c
            458-591             AC162945.6         75965-76098         c
            592-745             AC162945.6         72590-72743         c
            746-850             AC162945.6         69530-69634         c
            851-955             AC162945.6         68772-68876         c
            956-994             AC162945.6         67502-67540         c
            995-1135            AC162945.6         64659-64799         c
            1136-1216           AC162945.6         63322-63402         c
            1217-1232           AC162945.6         63038-63053         c
            1233-1364           AC162949.7         228699-228830       c
            1365-1496           AC162949.7         225139-225270       c
            1497-1569           AC162949.7         224135-224207       c
            1570-1925           AC162949.7         223538-223893       c
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 45.38 cM"
     gene            1..1925
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /note="carboxylesterase 1H"
                     /db_xref="GeneID:75704"
                     /db_xref="MGI:MGI:1922954"
     exon            1..101
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1741
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /codon_start=1
                     /product="carboxylesterase 1H precursor"
                     /protein_id="NP_001357759.1"
                     /db_xref="CCDS:CCDS90436.1"
                     /db_xref="GeneID:75704"
                     /db_xref="MGI:MGI:1922954"
                     /translation="MCLYALILLSLSAMAWGGYPSSPPVVNTTHGKVLGKYISLEGFT
                     QPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCSQDAVLGQMVNDLII
                     NNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGASAYDGRTLSA
                     HENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLAALHWIQDNIANFGGDPGSVTI
                     FGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKT
                     TTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVLPKAPEA
                     ILAEKNFNTVPYIVGINKQEFGWTLPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPE
                     DGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRGHRDAGAPTYMYEFQS
                     RPSFSSELKPKTVTGDHGDEVYSVFGAPILREGSSEEEINLSKMMMKFWANFARNGNP
                     NGQGLPHWPEYNQKKGYLQIGATTQQAQGLKDKEVSLWTELRAKKPPQTGHTEL"
     exon            102..309
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            310..457
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            458..591
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            592..745
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            746..850
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            851..955
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            956..994
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1135
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1216
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1364
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1496
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1569
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1570..1925
                     /gene="Ces1h"
                     /gene_synonym="2310039D24Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attacagatc agaactgaag acttcactcc actgcaagtc tgttttccca tgatgtgcct
       61 ctacgctctg attctgctgt ccctctcagc catggcatgg ggagggtacc catcctcacc
      121 ccctgtggtg aacaccactc atggcaaagt cctggggaag tacatcagct tagaaggatt
      181 cacacaacct gtggccgtct tcctgggagt cccctttgcc aagccccctc ttggatccct
      241 gagatttgct ccaccacagc ctccagagcc ctggagcttt gtgaagaatg ccacctcgta
      301 ccctcctatg tgctctcaag atgcagtgtt agggcagatg gtcaatgacc ttataataaa
      361 caacaaggag aaaattcgtc tgcggttttc agaagactgt ctctacctga atgtttacac
      421 gcctgtggac ttgatgaaga ataccaacag gctgccagtg atggtgtgga tccatggagg
      481 tggactggta gtgggcgggg catctgccta tgatggacga accctctcag cccatgaaaa
      541 tgtggtggtg gtgaccattc agtaccgcct ggccatctgg ggattcttca gcactggaga
      601 tgaacacagc cgggggaact ggggtcactt ggaccagcta gctgcactgc attggatcca
      661 ggacaacatt gccaattttg gaggggaccc tggttctgtg accatctttg gacagtcagc
      721 aggaggtgaa agtgtctctg ttcttgtatt gtctcctctg gccaagaacc tcttccatag
      781 agccatttcc cagagtggtg tggtcttcac ttctggtttg tttatggagg atgcaagttc
      841 agtgactgaa caaattgctg ttactgctgg ctgtaagacc accacatccg ctgtcattgt
      901 tcactgcttg cgtcagaaga cggaggagga gctcttagag atcatgcaaa aaatgaacct
      961 ttttaagctt gatgcacaag aaaataccaa aaagaactat ccttttttgc ccaccgtgct
     1021 tgatggagtg gtgctgccaa aggcaccaga agcgattctg gctgagaaga acttcaacac
     1081 agtgccctac atcgtgggaa tcaacaagca agagtttggc tggactctgc ccatgataat
     1141 ggaatttcca ccaactgatg taaaactgga caagaaggtc atctctctgt tcctgaggaa
     1201 gttggcgtat ttctttaaca taccagagga tggaattcca gttgccattg agaaatactc
     1261 aaaaggcaca gatgacccca tccaaaatag agtctggctc ctacagttga ttggggatgt
     1321 gatgtttggt ataccatctg tgattgtgtc tcgtggccac agagatgctg gagccccaac
     1381 ctacatgtac gaatttcagt ctcgtccaag cttctcatca gaattgaaac ccaagacagt
     1441 gactggagac catggagatg aagtctattc tgtctttggt gccccgattt taagagaggg
     1501 ttcctcagaa gaagagatta acctcagcaa gatgatgatg aaattctggg ccaactttgc
     1561 tcggaatggg aatcccaatg gtcaggggct gccccattgg ccagagtata accagaagaa
     1621 aggttacctg cagattggag ccaccaccca acaagcccag ggtctgaaag ataaggaagt
     1681 gtctttgtgg actgagctca gggccaagaa accaccacag acaggacaca ctgagctatg
     1741 aatgggaagc tctgccagcc tcaagagacc aacagagtca agatgaggat actctacaca
     1801 agatgtttgt tggtcaaaga taaatttttg caacaatgga aaattttgtc atagtgatgg
     1861 gcagaggcaa gggaggtgaa ttattgtttt tcaatttgga caataaatgg taatttttag
     1921 atcaa
//
