LOCUS       NM_001381922            1845 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus carboxylesterase 1B (Ces1b), transcript variant 2,
            mRNA.
ACCESSION   NM_001381922 XM_006531152
VERSION     NM_001381922.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1845)
  AUTHORS   Saul MC, Stevenson SA, Zhao C, Driessen TM, Eisinger BE and Gammie
            SC.
  TITLE     Genomic variants in an inbred mouse model predict mania-like
            behaviors
  JOURNAL   PLoS One 13 (5), e0197624 (2018)
   PUBMED   29768498
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1845)
  AUTHORS   Holmes RS, Wright MW, Laulederkind SJ, Cox LA, Hosokawa M, Imai T,
            Ishibashi S, Lehner R, Miyazaki M, Perkins EJ, Potter PM, Redinbo
            MR, Robert J, Satoh T, Yamashita T, Yan B, Yokoi T, Zechner R and
            Maltais LJ.
  TITLE     Recommended nomenclature for five mammalian carboxylesterase gene
            families: human, mouse, and rat genes and proteins
  JOURNAL   Mamm Genome 21 (9-10), 427-441 (2010)
   PUBMED   20931200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121985.3.
            
            On Apr 20, 2020 this sequence version replaced XM_006531152.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR2844020.1967255.1,
                                           SRR5189682.62791.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-76                AC121985.3         99539-99614         c
            77-281              AC121985.3         99029-99233         c
            282-426             AC121985.3         95733-95877         c
            427-560             AC121985.3         92885-93018         c
            561-714             AC121985.3         91541-91694         c
            715-819             AC121985.3         88950-89054         c
            820-924             AC121985.3         87738-87842         c
            925-1065            AC121985.3         84558-84698         c
            1066-1146           AC121985.3         83667-83747         c
            1147-1294           AC121985.3         82658-82805         c
            1295-1426           AC121985.3         79977-80108         c
            1427-1499           AC121985.3         77030-77102         c
            1500-1845           AC121985.3         76399-76744         c
FEATURES             Location/Qualifiers
     source          1..1845
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 44.99 cM"
     gene            1..1845
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /note="carboxylesterase 1B"
                     /db_xref="GeneID:382044"
                     /db_xref="MGI:MGI:3779470"
     exon            1..76
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1683
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2"
                     /codon_start=1
                     /product="carboxylesterase 1B isoform 2 precursor"
                     /protein_id="NP_001368851.1"
                     /db_xref="GeneID:382044"
                     /db_xref="MGI:MGI:3779470"
                     /translation="MWLHALVWASLALCPIWGHSPSSPVVDTTQGKILGKYTSLEGFE
                     HPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMCSQDAVAVQLLSDMLS
                     TKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGGASLYNGLALSAH
                     ENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTVF
                     GSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLGTNLRNKNIQAVTEMIATVSGCNDT
                     SSTAMVQCLRQKTENELLEITVKLDNTSMSTVIDGVVLPKAPEEILAEKSFSTVPYIV
                     GFNKQEFGWIIPTMLGDLLSEGKMNEETASLLLRRFHSDLNISESLIPAVIEKYLRGT
                     DDPAKKRDLLLDMFSDVFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVE
                     GDHGDEIFSVFGIPLLKEGTSEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEK
                     EGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEHREHK"
     exon            77..281
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            282..426
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            427..560
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            561..714
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            715..819
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            820..924
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1065
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1146
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1294
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1426
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1499
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
     exon            1500..1845
                     /gene="Ces1b"
                     /gene_synonym="382044; Gm5158"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagttcctg tccttccttc taccatgtgg ctccatgctc tggtctgggc ttctcttgct
       61 ctttgcccaa tatggggaca ctcaccctca tcaccggtag tggacaccac ccaaggcaaa
      121 atcctgggaa agtacaccag cttagaagga tttgaacacc ctgtggcagt tttcctggga
      181 gtcccctttg ccaagccccc tcttggatcc ctgaggtttg ctccaccaga gcctgcagag
      241 ccctggagct ttgtgaagaa tgccacctcc tatcctccta tgtgctctca agatgcagtt
      301 gcagtacagc tactctcaga tatgctcagc accaaaaagg agagcatacc tcccctgttt
      361 tccgaagact gtctctacct gaatatttac agccctgccg atttgacaaa aagcagtcta
      421 ttgcctgtga tggtgtggat ccatggtggt ggattgatga caggcggagc atcactctat
      481 aatggactag ctctctctgc ccatgagaac gtggtggtag taaccattca ataccgcctg
      541 ggtatttggg gattatttag cacaggtgat gaacacagcc gagggaactg ggctcacttg
      601 gaccagctgg ctgcactacg ctgggtccag gataacattg cgaactttgg agggaaccca
      661 gattcagtga ccgtctttgg gtcatcagca ggaggtgtca gtgtctctgt ccttgtctta
      721 tctcctctgg ccaaaaacct cttccacaga gctatttctg agagtagcgt ggtccttggt
      781 acaaacctgc gcaacaagaa tatccaggct gtgactgaaa tgattgctac tgtttctggg
      841 tgtaatgaca cctcatcaac tgccatggtt cagtgtttgc gccagaagac agagaatgag
      901 ctcttggaga tcacagtgaa actggacaat acctccatgt ccactgtgat agatggtgtg
      961 gtgctgccaa aggcaccaga agagatcctg gctgagaaga gtttcagcac tgtcccctac
     1021 atagtgggct tcaacaagca agagtttggc tggatcattc caacgatgtt gggagatctg
     1081 ctctctgaag gcaaaatgaa tgaggaaacg gccagtcttc tcttgaggag gttccactct
     1141 gaccttaaca tctctgagag tctgattcca gcagtcattg agaagtactt aagaggaaca
     1201 gatgaccctg ccaaaaagag agaccttctc ctggacatgt tttcagatgt attttttggt
     1261 atcccagctg tgctcttgtc ccgtagcctc agagatgctg gagtgtcaac ctatatgtat
     1321 gagtttcggt atcgcccaag cttcgtgtct gacaagagac cccagacggt tgagggagat
     1381 catggcgatg aaatcttctc tgtatttggg attccattat taaaagaggg tacctcagaa
     1441 gaggaaacca acctcagcaa gatggtgatg aaattctggg ccaactttgc tcgaaatggg
     1501 aaccctaatg gggagggtct gcctcactgg ccagaatatg atgagaagga agggtatcta
     1561 cagattggag ccactaccca gcaagcccag agactgaaag cagaggaagt ggctttctgg
     1621 actgagctcc tggctaagaa tccacctgag acagacccta ctgagcacag agaacacaaa
     1681 tgaatgggag gctctgccag tctcaggacc agaggagcga agatggaact attccacaaa
     1741 ggatgactat tcaccaaaga tggatcttac agaggaaact gcacacttgt acagtggaga
     1801 tatttgtatc tcaacttgaa agtaaatttc cttttagaaa tcaaa
//
