LOCUS       NM_133869               2814 bp    mRNA    linear   ROD 07-OCT-2024
DEFINITION  Mus musculus choline/ethanolaminephosphotransferase 1 (Cept1),
            transcript variant 1, mRNA.
ACCESSION   NM_133869
VERSION     NM_133869.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2814)
  AUTHORS   Funai,K., Lodhi,I.J., Spears,L.D., Yin,L., Song,H., Klein,S. and
            Semenkovich,C.F.
  TITLE     Skeletal Muscle Phospholipid Metabolism Regulates Insulin
            Sensitivity and Contractile Function
  JOURNAL   Diabetes 65 (2), 358-370 (2016)
   PUBMED   26512026
REFERENCE   2  (bases 1 to 2814)
  AUTHORS   Butler,P.L. and Mallampalli,R.K.
  TITLE     Cross-talk between remodeling and de novo pathways maintains
            phospholipid balance through ubiquitination
  JOURNAL   J Biol Chem 285 (9), 6246-6258 (2010)
   PUBMED   20018880
REFERENCE   3  (bases 1 to 2814)
  AUTHORS   Kulinski,A., Rustaeus,S. and Vance,J.E.
  TITLE     Microsomal triacylglycerol transfer protein is required for lumenal
            accretion of triacylglycerol not associated with ApoB, as well as
            for ApoB lipidation
  JOURNAL   J Biol Chem 277 (35), 31516-31525 (2002)
   PUBMED   12072432
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY226430.1 and AK037116.1.
            
            On Jun 14, 2014 this sequence version replaced NM_133869.3.
            
            Transcript Variant: This variant (1) encodes isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK037116.1, BC023783.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BY226430.1         3-43
            42-2814             AK037116.1         2-2774
FEATURES             Location/Qualifiers
     source          1..2814
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 46.49 cM"
     gene            1..2814
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /note="choline/ethanolaminephosphotransferase 1"
                     /db_xref="GeneID:99712"
                     /db_xref="MGI:MGI:2139793"
     exon            1..123
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            124..537
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..1449
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /EC_number="2.7.8.2"
                     /EC_number="2.7.8.1"
                     /EC_number="2.7.8.22"
                     /note="isoform 1 is encoded by transcript variant 1;
                     1-alkenyl-2-acylglycerol choline phosphotransferase"
                     /codon_start=1
                     /product="choline/ethanolaminephosphotransferase 1 isoform
                     1"
                     /protein_id="NP_598630.2"
                     /db_xref="CCDS:CCDS17723.1"
                     /db_xref="GeneID:99712"
                     /db_xref="MGI:MGI:2139793"
                     /translation="MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLS
                     RHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTIL
                     LVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSL
                     STVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQI
                     FIIIMHLLAVIGGPPFWQSMIPVLNIQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGK
                     NGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKL
                     VVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALIFSFFDLIRYCVSVC
                     NQIASHLHIHVFRIKASTAHSNHH"
     exon            538..685
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            686..827
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            828..912
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1044
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1203
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1329
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..2814
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2071..2076
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /note="hexamer: AATAAA"
     regulatory      2075..2080
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /note="hexamer: AATATA"
     polyA_site      2088
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
     polyA_site      2094
                     /gene="Cept1"
                     /gene_synonym="9930118K05Rik; mCEPT1"
                     /note="major polyA site"
ORIGIN      
        1 ttttctgagt cccccctctt tacggcaatc gtgaaagtgt cgtgaacgtg ctgccgccta
       61 tcagtcactc agtcgcctgg agtcggagtt gctatttcta ggcttgtgct tgttgggttc
      121 gggcccccag gtaaatagcc acagaaggct accaaacaag ataaataatt gtctccaagt
      181 agaagaaaac caagctccat gagtgggcat cggtcaacaa ggaaacgatg tggagattct
      241 cacccagagt cccctgtggg ctttgggcat atgagtacta cagggtgtgt attaaataaa
      301 ttgtttcagt taccgacacc accactgtca agacaccagt taaaacggct agaagaacac
      361 aggtatcaga gtgctggacg gtcccttctc gagcccttaa tgcaaggata ctgggaatgg
      421 ctagttggaa gagtaccctc atggattgcc ccaaatctca tcaccatcat tggactatca
      481 ataaatatct gtacaactat tttgttagtc ttctactgcc ctacagctac agagcaggca
      541 cctctgtggg cttatattgc ctgtgcttgt ggccttttca tttaccagtc tctggatgcc
      601 atagatggga aacaggccag aagaactaac agtagctctc ctctgggaga actttttgat
      661 catggctgtg actcactatc gacagttttt gtggttcttg gaacttgtat tgcagtacaa
      721 cttgggacaa atcctgactg gatgtttttt tgttgttttg ctgggacatt catgttctat
      781 tgtgcacact ggcaaacata tgtttctgga acattgcgat ttggaataat tgatgtgact
      841 gaagtgcaaa tcttcataat aatcatgcat ttgctggcag tgattggagg accacctttt
      901 tggcaatcta tgattcctgt gttgaatatt caaatgaaac ttcttcctgc actttgtact
      961 gtggcaggga ccatattttc ctgtacaaat tacttccgtg taatcttcac aggtggtgtt
     1021 ggcaaaaatg ggtcaaccat agcaggaaca agtgtccttt ctccttttct gcatattgga
     1081 tcagtgatca cgttagctgt tatgatctac aagaaatcag cagttcagct ttttgaaaag
     1141 catccatgtc tttatatact gacatttggt tttgtgtcgg ctaaaatcac taataagctt
     1201 gtggttgctc acatgacgaa aagtgaaatg catttgcatg acacagcatt cataggtcca
     1261 gcacttctgt ttctggacca gtattttaac agcttcattg atgaatatat agtactttgg
     1321 attgccttga tcttctcttt ctttgatttg attcgttact gtgtcagtgt ttgcaatcag
     1381 attgcatctc acctgcatat acatgtcttc agaattaaag cctctacagc tcactctaat
     1441 catcactaag gatgtgtctg ggttctacta agctcatggt tcctgcaaga aggaattcga
     1501 acatattaag gacaacaggg gtggataaga acaaatataa tttataataa tcaatgtcat
     1561 ataactttca ttctttgtta ctggtaacac tccctaactg tcctgtttag aatgggaatt
     1621 tcaggcccca tcctataaac tgaatatgtt gtcaaacagg gtttggctcc agaaagcatg
     1681 cagggaaact accgagtgtt tgtgattatt cagaatatca ctatcatagg agcacatccc
     1741 cactggtggt aaatctaatg taaaattttt gcaggccaaa agattgttgc tttatgattt
     1801 taacaaatca tcatcttttc gtaacacctt gtttattgtc ttctcagatg ttcttttgta
     1861 aggagctcag cttgtggcac atacatctta ctagcttgtg aggtgagagc agtgataagg
     1921 accttaaatt tagatggaag gtttcctgtc tgtatattgt tgaggaagtg attttattat
     1981 caatcaagaa atggtgtttc tcacgggctt gggaaatctt gatagcatgc agataatgtg
     2041 gtaactttgt caatccattt tattttttta aataaatata tgatctcaga accagctttt
     2101 ttctcaattt tattcagggg aactgtaaac taagtttcaa tgttttttaa aagttaaaca
     2161 aattttattt ctcttcttta acaattaagg aaatatggtc agccgtgtca tcatggtgtg
     2221 ttcatttttt tcaacctatg ggtctttatt ttgcagttat taccccatta tttcagtaat
     2281 tgttcagatg gggtggaggt gggttgtcac tttgtactct ccattttggt atttagactg
     2341 cgctttacca taggagccag gtttctctgt gaatcacatt tgctttcatt gtatacatat
     2401 tttctgtttc tttagtataa aggatagtga atcccagcac tcagaggtag aagcaggaag
     2461 aggagcagaa gttcaaggtt atccttgact ggagttgtag gctagtctgg gctatataag
     2521 acacagaaaa tcggaggggt caggatataa agataatctc tgacaaggca ggagaaagaa
     2581 gaggtaatcc tccattagta cagttatatc tattgtttta tttgattagt tcagcagacc
     2641 taacaggtgt ttatacctag tggaaattga gacctcaatt ggctaccagt tgtcacacag
     2701 tattgctaca tttgagaatg gaatttaggc tgtcattcta gctatttttt gtatcactcc
     2761 aaagctttaa actgaggtac tagagactaa ctgaaataaa tacatgtgtt ctag
//
