LOCUS       NM_144527               3878 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus centrosomal protein 85 (Cep85), mRNA.
ACCESSION   NM_144527
VERSION     NM_144527.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Chen,C., Tian,F., Lu,L., Wang,Y., Xiao,Z., Yu,C. and Yu,X.
  TITLE     Characterization of Cep85 - a new antagonist of Nek2A that is
            involved in the regulation of centrosome disjunction
  JOURNAL   J Cell Sci 128 (17), 3290-3303 (2015)
   PUBMED   26220856
  REMARK    GeneRIF: Cep85 is a bona fide Nek2A-binding partner that surrounds
            the proximal ends of centrioles where it cooperates with PP1gamma
            (also known as PPP1CC) to antagonize Nek2A
            Erratum:[J Cell Sci. 2015 Oct 15;128(20):3837. doi:
            10.1242/jcs.180463. PMID: 26471995]
REFERENCE   2  (bases 1 to 3878)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   3  (bases 1 to 3878)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 3878)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY250554.1, AK085545.1, AK141103.1, AV301648.2 and AW123366.1.
            
            On Nov 15, 2007 this sequence version replaced NM_144527.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141103.1, AK030742.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                BY250554.1         2-55
            55-1530             AK085545.1         2-1477
            1531-3313           AK141103.1         1521-3303
            3314-3861           AV301648.2         132-679
            3862-3878           AW123366.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 66.5 cM"
     gene            1..3878
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /note="centrosomal protein 85"
                     /db_xref="GeneID:70012"
                     /db_xref="MGI:MGI:1917262"
     exon            1..143
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            144..211
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            212..364
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            365..1059
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1193
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1311
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1497
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1650
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1805
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1899
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..1950
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            1951..2058
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2284
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     exon            2285..3866
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3847..3852
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /note="hexamer: AATAAA"
     polyA_site      3866
                     /gene="Cep85"
                     /gene_synonym="2410030J07Rik; Ccdc21"
                     /note="major polyA site"
ORIGIN      
        1 ggcgcgcgct ctggggcgtg cggcttgacg ggcgtggaac ggccgttagg cgacctgagg
       61 agcggattcg ccgctcgtgc ggacgtggtc ttcgccgtca gtgtcccaga gtgagtgggg
      121 tcgccgctcg ctctcaggcc tgtttgtctc aggtaactga tggccatgca agaaaaatac
      181 ccaaatgaca ggtctcatgc tacttcacca ggttccaatg tgattcaaaa aggcagttct
      241 ctgggaactg agtggcagac accagttatc tcagagacct ttcggagccg cttcagccgc
      301 tgctcaagca ttgctgacag tggggacaca gccattggga catcatgctc agacattgca
      361 gaggattttt gcagctcaag tggcagccct tccttccagc caatcaaaag ccacataacc
      421 attccaacag cccatgtgat gccttctact ttgggggcct ctcctgccaa accaaattct
      481 gcaccttccg ggccttcttc cgctaagctg cccttgtcag gattgactga aggcgtgggg
      541 atgacaagaa atggagactt cggagctgtg aagcgctctc caggcctagc aagggatttt
      601 atgtacctcc ctagtgctgc cggggagaat gggagtcagc agtcctggtt cccagcagtg
      661 ggccacgaga gagaggggga gatgaggaag ttcgatgttc ctagcatgga gtctaccctt
      721 aaccagccag ccatgctaga gacgttatac tcagatccac attaccgagc ccatttcccc
      781 aacccaagac ctgatacaaa taaggatgta tacaaagtat tgccagaatc caagaaggca
      841 ccgggcagtg gtgcagtatt tgagaggaac ggaccacatg ctagcagtag tggggtgctc
      901 cctttgggac tccagcctgc gcctggactt tccaagtcac tatcctctca ggtgtggcaa
      961 ccaagtcctg acccttggca tcctggagaa caatcctgtg aactcagtac ttgtcgacag
     1021 cagttggaat tgatccgttt acagatggag caaatgcagc ttcagaacgg agccatgtgt
     1081 caccatcctg ctgctttcgc tccattactg cccaccctag agccagcaca gtggctcagc
     1141 atcctgaaca gtaacgagca tctcctgaag gagaaggagc tcctcattga caagcaaagg
     1201 aagcatatct ctcagctgga gcagaaagtg cgagagagtg aactgcaagt ccacagtgcc
     1261 cttttgggcc gccctgcccc ctttggggat gtctgcttat tgaggctaca ggagttgcag
     1321 cgagagaaca ctttcttacg ggcacagttt gcacagaaga cagaagccct gagcaaggag
     1381 aagatggagc ttgaaaagaa actctctgca tctgaagttg aaattcagct cattagggag
     1441 tctctaaaag tgacactaca gaagcattcg gaggagggga agaaacagga ggaaagggtc
     1501 aaaggtcgtg ataaacatat caataatttg aaaaagaaat gtcagaagga atcagagcag
     1561 aaccgggaga agcagcagcg tattgaaacc ttggagcgct atctagctga cctgcccacc
     1621 ctagaagacc atcagaaaca gacggagcag cttaaggacg ctgaattaaa gaacacagaa
     1681 ctgcaagaga gagtggctga gctggagact ttgctggagg acacccaggc aacctgcaga
     1741 gagaaggagg ttcagctgga aagtctgaga caaagagaag cagacctctc ctctgctaga
     1801 catagctttc aagataaaca gtctgtggag gaagccaatg gagaaaacct cagagtggac
     1861 atggaatccc agcagaagga atgtgactcc ctccgaaaga tggtggagag gcaacagctg
     1921 aagatggaac agctgcactc ccaagtccag agccaaaagc aagaactggc acaagaagag
     1981 ggaatcaacc aggcactgag agaggaggcc cagcggaggg agacggccct gcagcagatg
     2041 cgcacagccg tgaaggagct ttcagtgcaa aaccaggacc tgattgagaa gaatctgacg
     2101 ctgcaagagc acttgcgcca ggcccagcca gggtcctcat cttcaccaga ctcagcccag
     2161 ctggcctgtg agctgcacca ggaactggcc agttgccttc aagatctgca agctgtctgc
     2221 agcattgtga cccagagggc ccagggccac aatcctaacc tctcactact cctaggcatt
     2281 cactccaccc agcacccagg gacgcagcta gatctacaaa agccagatgt gatcaggagg
     2341 aaactagaag aggttcaaca gctgcgccat gacattgagg acttaaggac cagcctgtca
     2401 gacagatatg cccaggacat gggagaaaac tgtgccacac agtgaggagt gccagggagg
     2461 acttaggctg ctgctgcctc gccagaaggt tccttccctg agagttctgc cttcagctgc
     2521 tgcacccaga ggggagagcc tgtatcttgt cccagggttg tgagaagcct gcctgttttg
     2581 ctgttctctg gctttgcctt attgggttat gttttgcttg ttatcttaat tcactcttaa
     2641 agactgagtt actaattaac ctttttgcag atttcaactg ataaagtcct cacaagttgt
     2701 tcccagctct aacctggcat gagaagcaaa caggctgctg gcctcccctc catcctccag
     2761 gacggatcca tgttcattcc tatccatacc ttggtcctac tgatgctctt ttaagagagg
     2821 cctaaagggt aaagtaggag tagcaacctt ttaagaattc tcaggcccct tgtatcagtc
     2881 ttctgagaac tcagctggct ttctgggttt tctcaggtac ctgtttcctc agggctgttg
     2941 ttcccacaga ggcctcaggg ttatccacct ctcagcagag cccctactat gatcactgac
     3001 ttggggacca tggcagggct cctcggcctg cctgctgggc catcttttac aggaaactct
     3061 tcctagctac ccattgtctg tccctagaac cttgggcatg tgggcatgtg cttgggtccg
     3121 ctatgtcgtc taggagtaca gactcctctg tggttgcctc gtggttcccg ggttggacat
     3181 gagtttcccc cgtaagagca cagggtggct gtggctgctc agtccttcct aaggctgggc
     3241 gctgtcgctg tcctctgaac tgtgcctctc atttggggtt aggagggttc ccttttcctg
     3301 ctctaacctt gacagttcgg agcacctaag ataaaaaaaa agtgttgagt gttttctggt
     3361 gttttgtgtt tctctaaggc ctttgagcct tagctttctg gtttttcttg cctcccaatt
     3421 tagggatcgt ctcagttgta tctggttatt tggccagccc tcaacctcct ctagtttgga
     3481 tccaagggcc ctgtatgtat gaggagtaaa gtagttgtgg gggtgcagac aggacttctg
     3541 ctaagccttg gggctgttaa cagcaccatg gacctccagg gcctgagggg ccgctttgcc
     3601 agtgttttaa caagtttatg ttttcttatg gagtggctta cctttcagag taatcacacc
     3661 cagctgacca tcccctcagc ctccgggctg ctgcctcctt aaaacagagc ttcctggttg
     3721 gtttccaccc tgttatcggg agcccagcct ccatgctcac gggtattttt cttcgtaaag
     3781 tttataaagt tatttatatg actctttgtt aagtcgactg gtttgtattg cctattttga
     3841 ttacagaata aaacatttaa caaacaaaaa aaaaaaaa
//
