LOCUS       NM_029852               3006 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus centrosomal protein 83 (Cep83), mRNA.
ACCESSION   NM_029852 NM_027479 NM_028100
VERSION     NM_029852.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3006)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3006)
  AUTHORS   Lee,H., Moon,K.H., Song,J., Je,S., Bok,J. and Ko,H.W.
  TITLE     Tissue-specific requirement of sodium channel and clathrin linker 1
            (Sclt1) for ciliogenesis during limb development
  JOURNAL   Front Cell Dev Biol 10, 1058895 (2022)
   PUBMED   36407107
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3006)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3006)
  AUTHORS   Shao,W., Yang,J., He,M., Yu,X.Y., Lee,C.H., Yang,Z., Joyner,A.L.,
            Anderson,K.V., Zhang,J., Tsou,M.B., Shi,H. and Shi,S.H.
  TITLE     Centrosome anchoring regulates progenitor properties and cortical
            formation
  JOURNAL   Nature 580 (7801), 106-112 (2020)
   PUBMED   32238932
REFERENCE   5  (bases 1 to 3006)
  AUTHORS   Ye,X., Zeng,H., Ning,G., Reiter,J.F. and Liu,A.
  TITLE     C2cd3 is critical for centriolar distal appendage assembly and
            ciliary vesicle docking in mammals
  JOURNAL   Proc Natl Acad Sci U S A 111 (6), 2164-2169 (2014)
   PUBMED   24469809
REFERENCE   6  (bases 1 to 3006)
  AUTHORS   Joo,K., Kim,C.G., Lee,M.S., Moon,H.Y., Lee,S.H., Kim,M.J.,
            Kweon,H.S., Park,W.Y., Kim,C.H., Gleeson,J.G. and Kim,J.
  TITLE     CCDC41 is required for ciliary vesicle docking to the mother
            centriole
  JOURNAL   Proc Natl Acad Sci U S A 110 (15), 5987-5992 (2013)
   PUBMED   23530209
REFERENCE   7  (bases 1 to 3006)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   8  (bases 1 to 3006)
  AUTHORS   Tanos,B.E., Yang,H.J., Soni,R., Wang,W.J., Macaluso,F.P.,
            Asara,J.M. and Tsou,M.F.
  TITLE     Centriole distal appendages promote membrane docking, leading to
            cilia initiation
  JOURNAL   Genes Dev 27 (2), 163-168 (2013)
   PUBMED   23348840
REFERENCE   9  (bases 1 to 3006)
  AUTHORS   Chen,H., Palmer,J.S., Thiagarajan,R.D., Dinger,M.E., Lesieur,E.,
            Chiu,H., Schulz,A., Spiller,C., Grimmond,S.M., Little,M.H.,
            Koopman,P. and Wilhelm,D.
  TITLE     Identification of novel markers of mouse fetal ovary development
  JOURNAL   PLoS One 7 (7), e41683 (2012)
   PUBMED   22844512
REFERENCE   10 (bases 1 to 3006)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: 4921537D05Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC070464.1.
            
            On or before Jul 25, 2007 this sequence version replaced
            NM_028100.1, NM_027479.1, NM_029852.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC070464.1, SRR1660815.12640.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3006
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 49.05 cM"
     gene            1..3006
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /note="centrosomal protein 83"
                     /db_xref="GeneID:77048"
                     /db_xref="MGI:MGI:1924298"
     exon            1..257
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            258..525
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     CDS             380..2458
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /note="coiled-coil domain-containing protein 41;
                     coiled-coil domain containing 41"
                     /codon_start=1
                     /product="centrosomal protein of 83 kDa"
                     /protein_id="NP_084128.2"
                     /db_xref="CCDS:CCDS36041.1"
                     /db_xref="GeneID:77048"
                     /db_xref="MGI:MGI:1924298"
                     /translation="MDTFPSLFPPGGDSRLNPEPEFQNMLIDERVRCEHHKHNYQALK
                     IEHKRLQEEYVKSQNELKRVLIEKQASQEKFQLLLEDLRGELVEKARDIEKMKLQVLT
                     PQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEYTFLKSEFEHQKEEF
                     TRVSEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRMEQLVREKTHLLQKLKSL
                     EAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQ
                     SSNEQNTCLISKLHRADREISTLASEVKELKHANKLEITDIKLEAARAKSELERERNK
                     IQSELDGLQSDNEILKSTVEHHKALLVEKDRELIRKVQAAKEEGYQKLMVLQDEKLEL
                     ENRLSDLEKMKVERDVWRQSEKEQCEEKLRASQMAEEAARRELQSTRLKLQQQIVNTE
                     KAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNHMLKDMVERLKQECRNLRSQA
                     EKAQLDVEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHE
                     NKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLI
                     LVPNMPPTASISPANFQSAVTVPGAELSFPPHLQEEQHQRELSLLRKRLEELETTQRK
                     QLEELGSPGE"
     exon            526..676
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            677..769
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            770..901
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1153
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1285
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..1400
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1545
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1695
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1771
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..1929
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            1930..2059
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2163
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2353
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..2986
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2488..2493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
                     /note="hexamer: AATAAA"
     polyA_site      2507
                     /gene="Cep83"
                     /gene_synonym="2600001G24Rik; 4921537D05Rik;
                     5730513H21Rik; Ccdc41"
ORIGIN      
        1 ctcaaccttt cccgaggcgt gggtgccctc gcggaccgtc cggctcctcg gttcgcctcc
       61 agccccgcgg cggcagcggc cgcttggacc gctccgggcc ccacacccca gccggtggga
      121 ccgtcccgag ccctcggccc caatgcctgg gagagcagag cggagtgggt ggcggtggtt
      181 ggagctgtgc cgggggctcc cggtggcgag cgcggctgct gtgctggggc gagcagcggg
      241 gaccgtgtgt gagtttggca tgatttggtc ccctgggatt ctgccttagc aagaaagaag
      301 ttggaaatac ttcctggaag aaaactaaaa caatacaaaa gccacagctt attgattgca
      361 tgtcagcccc cttacaaata tggacacatt tcctagccta tttccacctg gaggagatag
      421 taggctgaat cctgagcctg agttccaaaa tatgttaatt gatgaaaggg tacgctgtga
      481 acatcataaa cataattatc aggctctgaa aattgaacac aaaaggttgc aggaagaata
      541 tgtaaaatca caaaatgaac ttaaacgtgt attaattgaa aagcaagcaa gccaggaaaa
      601 attccaactg ctccttgaag acttaagggg agaattagta gagaaagcta gagacataga
      661 aaaaatgaaa ctgcaggtac taacaccaca aaaattggaa ttggtaaaag cccaactaca
      721 acaagaatta gaagctccaa tgcgagaacg ttttcggact cttgatgaag aagtggaaag
      781 gtacagagct gagtataaca agctgcgcta cgagtataca tttctcaagt cagagtttga
      841 acaccagaaa gaagagttta ctcgggtttc agaagaagag aaaatgaaat acaagtcaga
      901 ggttgcacga ctggagaagg acaaagagga gctacataac cagctgctta gtgttgatcc
      961 cacgagagac agcaaacgaa tggagcaact tgttcgagaa aaaacccatt tgcttcagaa
     1021 attgaaaagt ttagaggctg aagtagcaga attaagggct gagaaagaaa attctggtgc
     1081 tcaggtagaa aatgtccaaa gaatacaggt gaggcagttg gctgagatgc aggctacact
     1141 cagatccttg gaggctgaaa agcagtcagc taaactacaa gctgagcgtt tagaaaaaga
     1201 actacaatca agcaatgaac agaatacctg cttaatcagc aaactgcata gagctgaccg
     1261 agaaatcagc acactggcca gtgaagtgaa agagcttaaa catgcaaaca aactagaaat
     1321 aactgacatc aaactggagg cagcaagagc taagagtgag ctcgaaagag aaaggaataa
     1381 gatccaaagt gaacttgatg gattgcagtc agacaatgaa attctcaagt caactgttga
     1441 acaccacaaa gcgctcttag tggaaaaaga tcgtgaatta atacgtaaag tacaagctgc
     1501 caaggaagaa ggttaccaga aactcatggt cttacaagat gaaaagctag aacttgagaa
     1561 cagattatca gacttagaga agatgaaggt ggagcgtgat gtctggaggc agtcggaaaa
     1621 ggagcagtgt gaggagaagc tgcgggcctc ccagatggca gaggaggcag cccgcaggga
     1681 gctgcagagc actaggttaa aacttcaaca acaaattgtg aataccgaaa aagcagaaaa
     1741 agaaaaactt gaaaattctg aactgaaaca gcaaatcagt catttgcaga tccaagtgac
     1801 ctcactgaca cagtcggaga acgacttact gaattcaaac cacatgctga aggacatggt
     1861 ggagagacta aaacaagaat gccgaaattt aaggagccaa gctgagaaag cacaactaga
     1921 cgttgaaaag acactggagg aaaaacagat ccagtggttg gaagaaaagc acaagctcca
     1981 tgagcgaatc acagacagag aagaaaagta taaccaagcc aaggaaaagc tacagcgcgc
     2041 agcgactgct cagaaaaaga gaaaatctct tcatgagaac aaattgaaga gactacagga
     2101 gaaagtagaa gtcttggagg caaagaaaga agaactagaa acagaaaacc aggtgctaaa
     2161 tagacaaaat gttccatttg aagaatatac aaggcttcaa aaacgactaa aggacataca
     2221 gagaagacat aatgaatttc gaagtctaat tttggttcct aacatgcctc caacagcatc
     2281 gattagtcct gctaacttcc agtccgcagt gacagttcct ggagcggaac tctcttttcc
     2341 ccctcatctg caggaggaac aacatcaaag agagctctct ctccttcgca aaagactgga
     2401 agaactggag actacacaaa gaaaacaact ggaggagctt gggtctcctg gggagtgaag
     2461 cctgaagaca ggcaaagcca gagactcaat aaaagtctga cgggtaacgt gtggcactga
     2521 gacgccttct tcctgtttgc caaaatccat gagctgcctc aagaaaaggt actagcagcg
     2581 cactgcatgg gctccaagat tttaggatta tactaagaaa atgaaagtat tcatatattt
     2641 agaacatgca ttgacaatct tttgacaatg caaaaataaa aggaactagt tagttaaaaa
     2701 aatcaagttt tcaaattaat ttctgttttg ttgatatttt ctggcatttt gcttgaaata
     2761 tatccaccct gaagtccctt ttcctcatct ttgagatgcc tccttggtaa tgacaaaacc
     2821 aataaacatc tcctttatta tatataaaag ttttggaaaa gataatcatt tataagtata
     2881 aaaaccactt aaaagtttct aaacatgttt attatagaaa tctttacctt ttctaaaagc
     2941 tgtgcactta atttattgaa taacttaata aatatttttg tatctcaaaa aaaaaaaaaa
     3001 aaaaaa
//
