LOCUS       NM_028959               3632 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus centrosomal protein 72 (Cep72), mRNA.
ACCESSION   NM_028959 XM_908875
VERSION     NM_028959.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3632)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3632)
  AUTHORS   Chen,Z., Xu,Y., Ma,D., Li,C., Yu,Z., Liu,C., Jin,T., Du,Z., Li,Z.,
            Sun,Q., Xu,Y., Liu,R., Wu,Y. and Luo,M.
  TITLE     Loss of Cep72 affects the morphology of spermatozoa in mice
  JOURNAL   Front Physiol 13, 948965 (2022)
   PUBMED   36277211
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3632)
  AUTHORS   Hall,E.A., Keighren,M., Ford,M.J., Davey,T., Jarman,A.P.,
            Smith,L.B., Jackson,I.J. and Mill,P.
  TITLE     Acute versus chronic loss of mammalian Azi1/Cep131 results in
            distinct ciliary phenotypes
  JOURNAL   PLoS Genet 9 (12), e1003928 (2013)
   PUBMED   24415959
REFERENCE   4  (bases 1 to 3632)
  AUTHORS   Stowe,T.R., Wilkinson,C.J., Iqbal,A. and Stearns,T.
  TITLE     The centriolar satellite proteins Cep72 and Cep290 interact and are
            required for recruitment of BBS proteins to the cilium
  JOURNAL   Mol Biol Cell 23 (17), 3322-3335 (2012)
   PUBMED   22767577
REFERENCE   5  (bases 1 to 3632)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   6  (bases 1 to 3632)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3632)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ079657.1 and AK034892.1.
            
            On May 13, 2008 this sequence version replaced NM_028959.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034892.1, AK017134.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 CJ079657.1         15-22
            9-3632              AK034892.1         2-3625
FEATURES             Location/Qualifiers
     source          1..3632
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 40.15 cM"
     gene            1..3632
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="centrosomal protein 72"
                     /db_xref="GeneID:74470"
                     /db_xref="MGI:MGI:1921720"
     exon            1..102
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..1964
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="centrosomal protein 72 kDa"
                     /codon_start=1
                     /product="centrosomal protein of 72 kDa"
                     /protein_id="NP_083235.3"
                     /db_xref="CCDS:CCDS26639.1"
                     /db_xref="GeneID:74470"
                     /db_xref="MGI:MGI:1921720"
                     /translation="MAPGQRLVLCEETVRERSGLGPHRDLAELRSLSIPGTYQEKITH
                     LGNSLMHLTALKSLDLSRNSLVSLEGIQYLVSLESLNLYYNCISSLAEVFRLHTLLEL
                     QDVDFRLNPVVKNESDYRLFVVHMLPKLRQLDDRPVRESERKASQLHFAPEDSLNSKE
                     NFSTTLTVGRPHHLRNRCTETSAKKCLVMDADDEAVLNLIAECEWDLSNPPGNMSSSQ
                     KEHEADLHYAQESRHLLSPLSIQHQCGDSARRGHEKKKVTSRGCPGHSPQDQLCGELP
                     LQHGLPEACHMHVQHARITSQPDSVDVEDCASSAQKSSLSSQKTVNPLPVPEKYRKRR
                     MPGGRFQVPSDRECLSFLERADGPSSLEDSLSRQDGLEGQSQVALSHSEALEAEERTS
                     HGTSDPRVLSPKLCSAAVPERRSTLEVALLEALLDLIDRCSSGSGSLHGNEAFLAQAK
                     HVLSSLQEFTATRDSSALEKEGIGYLSLENKTLQSRLAEQQQQYTATVTKMTAELNNT
                     KRELDTLRQHLDKSLEENSHLKSLLYNVKKEVKTADTSTALTLQITGLQASMKQLSGE
                     VVELKQHVEHYDKIQELTQMLQESHSSLVSTNEHLLQELSRTRAQHRAEVEQMRWSFQ
                     EFKKTTALIPHRSSRRGGRQSC"
     exon            103..230
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            231..423
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            424..532
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            533..711
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            712..918
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1223
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1362
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1363..1559
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..1686
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1798
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..3632
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2471..2476
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2495
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="major polyA site"
     regulatory      3292..3297
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="hexamer: ATTATA"
     polyA_site      3312
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="major polyA site"
     regulatory      3608..3613
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3629
                     /gene="Cep72"
                     /gene_synonym="2610029E11Rik; 4933440J22Rik"
ORIGIN      
        1 gcgccagcgt ccggtttgaa aacatggcgc caggccagcg gttggttttg tgtgaagaga
       61 ctgtacgaga gcgcagcggc ctgggtcccc accgcgacct ggctgaactt cgatctttat
      121 ctattcctgg aacataccaa gagaagatta ctcacctggg aaactctctg atgcacttga
      181 cagctctaaa atccttagac ctctcacgta actccttggt tagccttgag ggtatacagt
      241 atctggtctc cttggagagt ctcaatctct actacaactg tatttcttca ttagcagaag
      301 tatttaggct ccacacccta ctggagctcc aggacgtgga cttccggctt aaccccgttg
      361 tgaagaatga gtctgactac cgcctgtttg tcgtgcacat gctcccgaag ctccgacagc
      421 tagatgaccg tcctgtgaga gaaagtgagc ggaaagcttc ccagcttcat tttgccccag
      481 aagattcact gaactcaaag gagaacttct caaccacttt aaccgttgga agaccacacc
      541 acctcagaaa cagatgtact gagacctcgg ccaaaaaatg cttggtcatg gatgctgatg
      601 atgaggctgt cctgaacctt attgccgagt gtgaatggga cctaagcaat cctcctggga
      661 acatgagctc cagccaaaag gaacatgaag ctgacctcca ttatgcccaa gagtccagac
      721 atctgttgag tcctttgtcc atccagcacc agtgtgggga ttcagcgagg cgaggccatg
      781 agaagaagaa agtcacctcc agagggtgtc caggtcattc accgcaggac cagctctgtg
      841 gggaactccc cctacagcat ggcttgccag aggcctgcca tatgcacgta cagcatgccc
      901 gcatcacttc acagccagac tctgtggatg ttgaggactg tgcttcatct gctcagaaat
      961 caagtttgtc atcacaaaaa acagtaaatc ctttgcctgt ccctgaaaag tacaggaagc
     1021 gaaggatgcc tggtgggaga ttccaggtgc cttcagaccg ggagtgtttg agcttcctag
     1081 agagggctga cgggccctcc agccttgagg acagtctaag cagacaggat ggcttggagg
     1141 gccagagtca ggtggccttg tctcactctg aggctttgga ggctgaagag cggacatctc
     1201 atggcacaag tgaccccaga gtgctgtctc ctaaactctg ctcggcagcg gtgcctgagc
     1261 ggaggtccac tctggaagtg gcccttctgg aggcgcttct cgacctgata gacaggtgct
     1321 caagtggcag tggatccctg catggcaatg aggccttcct tgctcaggcc aagcatgttt
     1381 tgtcatctct tcaagagttc acagcaactc gggacagttc agcacttgaa aaggaaggaa
     1441 ttggttacct atctcttgaa aataagactc tgcaaagccg ccttgctgag caacagcaac
     1501 agtatactgc tacagtgacc aagatgacag cagagctcaa taatacaaag agggagctgg
     1561 acacattgag acaacatttg gacaaatcat tggaagagaa tagccactta aagtctcttc
     1621 tgtacaatgt gaaaaaagaa gtaaagactg cagacacttc aactgcactc actttgcaga
     1681 tcactggact tcaggcaagt atgaagcagc tctctgggga agttgtggag ctgaagcaac
     1741 acgtggagca ctatgacaag atccaggagc tcacacagat gcttcaagag agccacagct
     1801 ccctggtaag caccaatgag catctcctgc aggagctgag ccgcacacgg gcacagcata
     1861 gagctgaggt agagcagatg cgctggagct tccaggaatt taagaagact acggccctga
     1921 tccctcaccg tagctcccga cgtgggggcc ggcagtcctg ctagctgcta gtgagctgta
     1981 ctctcctcca tcagggaaag ccccagggtt gtacctgggc atgcatctat ctaagtaccc
     2041 cagtgagact gtaattacct taggatcctc aaaatgtgtt cataaactca gcttgcttat
     2101 gtgttctgaa ttgatgcagt cgaccctggg gcttcgcatg tttgagaagc ttggttaatt
     2161 acacatgctg ttgtacagta cctgcaggag ttttttcttc ccaatgtggg aaagttttgt
     2221 atagttaaaa tgttctcatg tgacaagcat tccttattga aagaaataat atattgctat
     2281 gtttaaaaag ttaacttttt aagtggctct tcataaatta taactgactt ccttattgaa
     2341 ttcttgtata aaacaagtta tacaaagtga gcaggaaaaa ataagttcca agttctaata
     2401 aaaagtaata cttatagctg tgacaaatgt tttaagaatt tgtgtgatat taacatgtca
     2461 cagcaaaaca aataaacaaa caaaaaacct ccccacttct ggttcactct ttttgctttc
     2521 aatagctcct gaaaaccagg ggaagattta aatacacact gtacagagcg agacccagat
     2581 gactgtgtga aaggtgctca ttagaagagg cagatgtaat ccactggaca gtactatcta
     2641 gagtgaagcc tgtgcagaga gatagctctt acacactaat gctgctgagt acagacattc
     2701 ggagacagct tggaattgcc taacggacct ttttctctgc ctcataaaat cagaaagatt
     2761 ctcctgccct ccacttctgc acttgcccag gtgggttttg tgttcaaggc aggaagtgag
     2821 tttcaagcct caactttgag gctttgaggg ctctcagctg tgttctgcag ccccttatta
     2881 ccccaagtca ggagttgtac agctagctgt ctatttctgt ttgagttctt gtacatcatg
     2941 tatatctatg aattaattta tattgcctta attttcggat tatttttggt actgataatc
     3001 ttttgttagt gttttaatag cttcggggtt tgaagttgta tcactgtgta gacttgttgt
     3061 gacacttgac ttttaaataa gagttcatta tctgggtaag aagatagctt ctggacatca
     3121 gctttcatac tgcagacatg ctcatcaagc cagtgaacaa gcaggcctga ccttcccatc
     3181 gccagtgacg ggtgaacttg agagcatgct ggtggctgtc ctgaactttg tcagctgtgt
     3241 atctgcagaa ccagcttcct gtcttccctt cctggtggtg ctgcccatga cattatacat
     3301 tttccaaaac cactgacgta gttgagtttg tttcatcagt tttcctgttt tgtatttgac
     3361 tttgttctat ctgccttccc attttgtata ctttctctag tctgttttgg ttattttgtt
     3421 tttctggctc cagtattgtc atttttgttt gttcagttag tggttaattt ttctcttttc
     3481 tttttccttt tctttttctt tttctgttga gacaaggtcc ttactggcta gcctggagct
     3541 cacaatgtag atcaggctgg cctcaaactc ccagagatcc tcttgcctct gcctcctgag
     3601 tgctgggatt aaagatctgt atgatcactc gt
//
