LOCUS       NM_025345               1438 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus centrosomal protein 20 (Cep20), mRNA.
ACCESSION   NM_025345
VERSION     NM_025345.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Xu,Z., Liu,M., Gao,C., Kuang,W., Chen,X., Liu,F., Ge,B., Yan,X.,
            Zhou,T. and Xie,S.
  TITLE     Centrosomal protein FOR20 knockout mice display embryonic lethality
            and left-right patterning defects
  JOURNAL   FEBS Lett 595 (10), 1462-1472 (2021)
   PUBMED   33686659
REFERENCE   2  (bases 1 to 1438)
  AUTHORS   Srivastava,S. and Panda,D.
  TITLE     A centrosomal protein FOR20 regulates microtubule assembly dynamics
            and plays a role in cell migration
  JOURNAL   Biochem J 474 (16), 2841-2859 (2017)
   PUBMED   28694353
  REMARK    GeneRIF: The results suggested that the centrosomal protein FOR20
            is a new member of the microtubule-associated protein family and
            that it regulates the assembly and dynamics of microtubules while
            interacting with tubulin.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1438)
  AUTHORS   Fujitani,M., Zhang,S., Fujiki,R., Fujihara,Y. and Yamashita,T.
  TITLE     A chromosome 16p13.11 microduplication causes hyperactivity through
            dysregulation of miR-484/protocadherin-19 signaling
  JOURNAL   Mol Psychiatry 22 (3), 364-374 (2017)
   PUBMED   27378146
REFERENCE   4  (bases 1 to 1438)
  AUTHORS   Sedjai,F., Acquaviva,C., Chevrier,V., Chauvin,J.P., Coppin,E.,
            Aouane,A., Coulier,F., Tolun,A., Pierres,M., Birnbaum,D. and
            Rosnet,O.
  TITLE     Control of ciliogenesis by FOR20, a novel centrosome and
            pericentriolar satellite protein
  JOURNAL   J Cell Sci 123 (Pt 14), 2391-2401 (2010)
   PUBMED   20551181
  REMARK    Erratum:[J Cell Sci. 2010 Jul 15;123(Pt 14):2521]
REFERENCE   5  (bases 1 to 1438)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC011300.1.
            
            On Jun 10, 2003 this sequence version replaced NM_025345.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC011300.1, SRR1660815.8213.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 9.74 cM"
     gene            1..1438
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /note="centrosomal protein 20"
                     /db_xref="GeneID:66086"
                     /db_xref="MGI:MGI:1913336"
     exon            1..39
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..536
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /note="lisH domain-containing protein C16orf63 homolog;
                     lisH domain-containing protein FOPNL; FOP-related protein
                     of 20 kDa; FGFR1OP N-terminal-like protein; Fgfr1op
                     N-terminal like"
                     /codon_start=1
                     /product="centrosomal protein 20"
                     /protein_id="NP_079621.1"
                     /db_xref="CCDS:CCDS27973.1"
                     /db_xref="GeneID:66086"
                     /db_xref="MGI:MGI:1913336"
                     /translation="MATVTELKAVLKDTLEKRGVLGHLKARIRAEVFNALDDDREPRP
                     SLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLIRELNAFEESKDN
                     SIPLLYGILAHFLRGPPDGAQNVLLTESTLHPATKHLSWKPSRRPDDDHVRKDTGPRT
                     TTEELPAAAQAVSR"
     exon            40..237
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /inference="alignment:Splign:2.1.0"
     exon            238..322
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /inference="alignment:Splign:2.1.0"
     exon            323..456
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /inference="alignment:Splign:2.1.0"
     exon            457..1422
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1402..1407
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /note="hexamer: AATAAA"
     polyA_site      1422
                     /gene="Cep20"
                     /gene_synonym="0610037P05Rik; Fopnl"
                     /note="major polyA site"
ORIGIN      
        1 gccgttgaaa aatggcgact gttacggaac tgaaagctgt tttaaaggac accttggaaa
       61 aaaggggagt gttaggacat ttaaaagcaa ggatccgtgc tgaagttttc aatgccctgg
      121 atgatgatcg tgaaccccga ccgtctttgt ctcatgagaa ccttctaatt aatgaattaa
      181 ttagggagta tttggaattc aataaatata aatacacagc ctctgtcctc atagcagaat
      241 ctggtcaacc tgtagttcca ttggacagac agtttctcat ccgtgaacta aatgcctttg
      301 aagaatcaaa ggataactca attcctctat tgtatggaat tttagcccat ttcttgcgtg
      361 gtcctccaga tggagcccag aatgtgcttc tgacagagtc aaccctgcac ccggcaacca
      421 agcatctcag ctggaagccc agcagaagac ctgacgatga ccacgtgagg aaggacacag
      481 ggccaagaac cacaactgaa gagcttcctg ctgctgcaca agcagtcagc agatgatgcg
      541 atgcatacac caggctcatc acctcagctg tgtgtggagt aaccgacgta ttattcccaa
      601 tgccatcaat tagaccacca ctgcttgtaa atgtttgagt gtctgcattc agccactcat
      661 ggtttactgc atctgtggaa agctgatctg tcgtctcgct tgctggatgc cactggggaa
      721 aatttattgt tttcaggatg tatttttaaa gttctcattt gtgaaatctg aaagggcttt
      781 ttagtacttt gtatagggtt ttgttttggg ttttttggcc agctctaagg gctgttgcta
      841 tgctgctggt aaagcacttc cctccctatg caaggtcctg ggttcagtcc tagcactgaa
      901 gaaagaaagc acaagaacag gtctttgtcc atgtgctctg ctcattaaac ttttttcagc
      961 tagaagtata tggacctatg gggaaagtca ttcatgtttt gaaaaaatat ctaaaggaat
     1021 attaaaacca gaacttaatt tatatgaagt ttgatttttt aaaaaatacc tgaattatta
     1081 ttgcctgccc tggctagttt tatatcaact tgatacaagc tagagtcatt tggggagagg
     1141 gactctgaat tgagaaaatc cctccatcag attggcttat gggcaaacct gtagtacatt
     1201 tttcttgatt catgattgat atgggagggt ccagcccaca gtgggtggtg tcacccctgg
     1261 gcaggtgatc ctgggttcag taagaaagac tgagcaagcc atggggagca agccactaag
     1321 tagcactcct ctgtggcctc tgcattaact tctgccgtga tttctctcag tgacaaactg
     1381 tgatgttgaa ctgtaagctg aaataaacct tcttcttccc aaaaaaaaaa aaaaaaaa
//
