LOCUS       NM_199316               5295 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus centrosomal protein 162 (Cep162), mRNA.
ACCESSION   NM_199316 XM_001000297 XM_001480975
VERSION     NM_199316.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5295)
  AUTHORS   Xie,Z., Moy,L.Y., Sanada,K., Zhou,Y., Buchman,J.J. and Tsai,L.H.
  TITLE     Cep120 and TACCs control interkinetic nuclear migration and the
            neural progenitor pool
  JOURNAL   Neuron 56 (1), 79-93 (2007)
   PUBMED   17920017
REFERENCE   2  (bases 1 to 5295)
  AUTHORS   Leon,A., Omri,B., Gely,A., Klein,C. and Crisanti,P.
  TITLE     QN1/KIAA1009: a new essential protein for chromosome segregation
            and mitotic spindle assembly
  JOURNAL   Oncogene 25 (13), 1887-1895 (2006)
   PUBMED   16302001
REFERENCE   3  (bases 1 to 5295)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   4  (bases 1 to 5295)
  AUTHORS   Tomsig,J.L., Snyder,S.L. and Creutz,C.E.
  TITLE     Identification of targets for calcium signaling through the copine
            family of proteins. Characterization of a coiled-coil
            copine-binding motif
  JOURNAL   J Biol Chem 278 (12), 10048-10054 (2003)
   PUBMED   12522145
REFERENCE   5  (bases 1 to 5295)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK135482.1, AK129260.1, CK639077.1, BB413728.1, CN456181.1,
            CB246096.1, BC028799.1, BF465741.1, AI049385.1 and BF721651.1.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_001480975.1, XM_001000297.1, NM_199316.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151104.1, SRR17253013.4445717.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-894               AK135482.1         2-895
            895-2530            AK129260.1         228-1863
            2531-2808           AK135482.1         2531-2808
            2809-2957           CK639077.1         112-260
            2958-2958           BB413728.1         238-238
            2959-3256           CK639077.1         262-559
            3257-3594           CN456181.1         270-607
            3595-3865           CB246096.1         166-436
            3866-4671           BC028799.1         1-806
            4672-4718           BF465741.1         578-624             c
            4719-4719           AI049385.1         13-13
            4720-5172           BF465741.1         124-576             c
            5173-5295           BF721651.1         1-123               c
FEATURES             Location/Qualifiers
     source          1..5295
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 46.78 cM"
     gene            1..5295
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="centrosomal protein 162"
                     /db_xref="GeneID:382090"
                     /db_xref="MGI:MGI:1925343"
     exon            1..270
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            271..387
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     CDS             331..4542
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="protein QN1 homolog"
                     /codon_start=1
                     /product="centrosomal protein of 162 kDa"
                     /protein_id="NP_955020.2"
                     /db_xref="CCDS:CCDS52879.1"
                     /db_xref="GeneID:382090"
                     /db_xref="MGI:MGI:1925343"
                     /translation="MAHYFKVDLDEEFERFMKELSDDSFENSNKTPRQPNEDNKEMKK
                     KDPVPWWIAEDDFEDDGLLGTNVSYLKTKKTYQPVMDTEEESAEKVQFLKSSGTSILS
                     VDSLEANELVVSEPHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDS
                     DDSAQLKALHRYPRNTEPAEDGCENESEQEELPETYSDDFEDAEDADDPLITKDEETH
                     PKENSESGKDSFPKQEEEKTGMLANVVLLDSFDSVEDVGLSSQEKATPKAKAPPEITD
                     DGPAETGVPYGQSSGDTEALHQAYCHVAHSLGDTGEPRIEASTVQTVRSSIKDGLQEN
                     EESSKNVSTTESDLPTVEELMQPIRIDSYGIRAFDLQPISLKKATDSKEAESVGSLPL
                     KTNTNTVSQDTRHAIQFPHKHDESVVLHRTADEGMGSSCPATEEHLDKMYLEILKKKT
                     SVNPSLLPQDDKMNQTSRSQLGAGEEVPVIGKQVPCKKARSTPSLPKRKPQSGLYASA
                     RSSGYGKPSSPLQLFSALEKKTSKDNTKTKSVRSIPTSNQFRKREILSGTKLIKPAAS
                     NKPSPHREGSPATPKRPEDPSDDSFVQLQTEPLGSYGGNREKELLMLKRAQDAEEKWT
                     GAQALMEQMKMTFCEKEKELENTVESLKRQQERELFRLNQENYILQAKLSSFEETSRK
                     QRWLQFGETSDPLTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEE
                     RMFKENQNLFSELASLKEQMHKNHFLSQAVENTEPTKNQSFTDLLAELRAAQKEKNHL
                     MEDIKRLKQDKQALEVDLEKVKRERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQ
                     KRLQWYAENQELLDRDAARLREANEETEKLRLEIEKLKTESGSPATQQRLRSKERALD
                     AKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSVDRNTVEFMERRIKKLEAD
                     LEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRQKEAPQSQRNSSSRLKAL
                     ETELGDIKEAHQITVRKLEAEIDVLKHQNADLEHKKNDKGDQGLQSIEFQVEQAQARA
                     KLARLNEELAAKGREIQDLTKTVERLQKERRMMLSRQIPRSREETAAKRLKKDPNRGH
                     GNAFPETLDGKLYHPHTFTDSHISEVLEENYRLRSELEGLILERSKLKMESEAAVCQL
                     ENSMKRVKDDAAAHIASLKASHEREIEKLLCQNAIENSSSKVAELNRKIATQEVLLKH
                     FQGQVNELQGKQESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIK
                     QMEMRHRQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILD
                     VLRELHRQGVVVPMALAGEENTAEF"
     exon            388..511
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            512..658
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            659..842
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            843..910
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1029
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1060
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1177
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1369
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1451
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1725
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1987
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            1988..2118
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..2346
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2347..2487
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2488..2600
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2601..2706
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2707..2833
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2834..2997
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            2998..3102
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            3103..3315
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            3316..3959
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            3960..4101
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            4102..4200
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            4201..4335
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     exon            4336..5295
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4650..4655
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="hexamer: AATAAA"
     polyA_site      4674
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="major polyA site"
     regulatory      4710..4715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="hexamer: ATTAAA"
     polyA_site      4729
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="major polyA site"
     regulatory      4839..4844
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
                     /note="hexamer: ATTAAA"
     polyA_site      4864
                     /gene="Cep162"
                     /gene_synonym="4922501C03Rik; mKIAA1009"
ORIGIN      
        1 gagctcggga tttccgggag taagagaaag cgggatgtgc acactgctgc cgcgcccacg
       61 tcccttacgg ccgccacatc ctgcagagcc gtgaaggttc caatctttat ttgagagtca
      121 ccagaagact gacagcttgt ctggctgctc cctgggtcac gtggcaggca ggatcacgtg
      181 acacccggga gcccgcctgt aggggtctgt tgccctgaca acagcccgct cgccgggact
      241 ttccgggaga gcgcgggctc ccaggagcag tgtttccaat gctgtgaata attttaagat
      301 acttgctttg tgacgtgaaa attactaacc atggctcact atttcaaagt agaccttgat
      361 gaagaatttg aacggtttat gaaggagctt tcagatgatt cttttgaaaa ttcaaataaa
      421 acacctagac aacctaatga agacaacaaa gaaatgaaga agaaagaccc agtgccttgg
      481 tggatagccg aagatgattt tgaagatgat ggattgcttg gaacaaatgt gagctatttg
      541 aagacaaaga agacatatca gcctgttatg gacacagagg aggaatctgc tgaaaaagtt
      601 cagtttctta agagcagtgg aacctccatc ttaagtgttg acagcttaga agctaatgaa
      661 ttggttgttt ctgagcccca tcatagcact cttggtttgg gcttggacac gttagaagaa
      721 caagaggaga aagagcagtt ctttgccagg cttgagaaag gcttgacgtc ttctattgat
      781 tattcgaaat taaatcaaga actagattct gacgactctg cacaattgaa agctttacat
      841 agatatccac gtaatacaga gccagctgaa gatggatgtg agaatgaatc agaacaagag
      901 gaactgccag aaacgtacag tgatgatttt gaagatgctg aggatgctga tgatcctttg
      961 attactaaag atgaagagac ccatcccaaa gaaaactctg agtcaggaaa agacagcttt
     1021 cccaaacagg aggaagagaa aactggcatg ctggctaatg ttgtgctgct tgattccttt
     1081 gactctgttg aagatgttgg ccttagcagt caagagaaag caacccctaa agcaaaggcc
     1141 cctccagaaa taacagacga cggaccagca gaaacaggtg ttccttatgg acaaagcagt
     1201 ggtgacactg aagccctgca ccaagcttac tgtcatgtag ctcattctct gggagacaca
     1261 ggcgaaccaa gaattgaggc tagcactgtg caaactgtca ggagctccat aaaagatggt
     1321 cttcaagaaa acgaagagtc ttcaaagaac gtctctacca ccgagtccga tttgcccaca
     1381 gtggaggagc tgatgcagcc tatcaggatc gattcctatg ggatcagggc ctttgacttg
     1441 cagcctatca gccttaagaa agcaacggac agtaaagaag ctgaatctgt aggctcttta
     1501 cccctgaaga caaacacaaa cactgtgtct caagacacta gacatgcgat ccaatttccc
     1561 cacaaacacg atgagagtgt ggttctacac aggacagcag atgagggcat gggcagcagc
     1621 tgtccagcta cagaggagca tttggacaaa atgtatctgg agattttgaa gaagaaaaca
     1681 tcagttaacc cctcactatt acctcaggat gacaaaatga accagacttc caggtcccag
     1741 ctcggggctg gggaagaggt gcctgtcatt ggtaaacagg ttccatgtaa gaaggccaga
     1801 agcacacctt ctttgcctaa gagaaagcca cagagtggac tgtacgcatc agctcggagc
     1861 tcaggctacg gcaaacccag ttcaccactc cagttatttt cagcccttga aaagaaaact
     1921 tcaaaggata atacaaaaac taaaagtgtg agatccattc ccacctcaaa tcaatttaga
     1981 aaaagagaaa tactatctgg aacaaaactc atcaagcctg cagcttcgaa taaaccatcc
     2041 cctcaccgtg aaggtagccc agctacaccc aagagacctg aagacccctc agatgattcc
     2101 tttgttcagt tacagactga gcctttggga tcctacggtg ggaacagaga gaaagagtta
     2161 ctaatgttga aaagagctca ggatgcggag gaaaaatgga cgggtgcaca agcactgatg
     2221 gagcaaatga aaatgacatt ctgtgagaag gagaaggaac tggagaacac agtggaaagc
     2281 ctcaagaggc aacaggagag agagctcttc agactgaacc aagagaacta cattctccag
     2341 gccaagttaa gtagctttga agaaacaagc agaaaacaga ggtggctaca atttggagaa
     2401 acatctgacc ccctcactgg agagaaactg aaacaaattc aaaaagagat acaagagcaa
     2461 gagacacttc ttcaaggcta ccagcaggaa aatgaaaggt tgtataatca agtaaaagat
     2521 cttcaggaac aaaataagaa aaatgaagag cgaatgttta aagaaaatca gaatttattt
     2581 agtgagttgg cctctttaaa agaacagatg cacaaaaatc attttctgtc tcaagcagtt
     2641 gaaaatacag aacccacaaa aaaccagagt tttacagatc ttctagcaga attacgggcg
     2701 gcacagaaag aaaaaaacca cctcatggaa gacatcaaaa gactgaagca agacaaacaa
     2761 gctctggagg tagacttgga aaaagttaag agagagaggg accaagccaa agatcaaatc
     2821 gcctatgcca caggtgaaaa attatatgaa ataaagattt tagaagaaac acataaacaa
     2881 gaagtgagtc gtctacaaaa gcgactacag tggtacgctg aaaaccagga gcttctggat
     2941 agagacgcag ctcgcctccg agaggccaat gaagagactg agaagctgag attagagatt
     3001 gaaaaactga aaactgagtc tgggagccca gctactcagc agaggctgcg ctcaaaggaa
     3061 agagctcttg atgccaaaag aattcaggat ctggagcggc aggttaaaga aatggaaggg
     3121 attctgaaga gaaggtatcc caactctttg cctgctttga tactggctgc ctcggcagct
     3181 ggtgattcgg tagatagaaa tacagtggag tttatggaga gaagaataaa aaagctagaa
     3241 gctgatctgg agggcaaaga tgaagaagcc aagaaaagcc ttcgcaccat ggaacagcag
     3301 tttcagaaaa tgaagattca gtacgaacag cggctagagg agcaggaaca gctgcttgcc
     3361 cacaggcaga aggaagctcc gcagagccag cgtaacagct catccaggct gaaggccctt
     3421 gagacagaac ttggggacat aaaggaagcc catcagatca ctgtaagaaa gctggaagct
     3481 gaaatagatg ttctcaaaca tcaaaatgct gacttagaac acaagaagaa tgacaaagga
     3541 gatcagggcc tccagtccat agagttccag gtggagcagg cgcaggccag ggcaaaactg
     3601 gcgagactca atgaagagct ggcagcgaag gggagagaga tacaagacct tacaaagacc
     3661 gtggagaggc tccagaagga gagaaggatg atgctgtcga ggcagatccc caggagcaga
     3721 gaggagacgg ctgccaaaag gctgaagaaa gacccaaaca gaggacatgg gaatgctttc
     3781 cctgaaaccc tggatggcaa actgtatcac ccacacacct ttactgactc tcatatttcg
     3841 gaggtcttag aagaaaacta cagattgaga agtgagctgg agggcttaat tttagagaga
     3901 agtaagctga agatggaatc tgaggcagca gtatgccaac ttgaaaactc catgaaaagg
     3961 gtcaaggacg acgctgcagc gcacattgcg tccctcaaag catctcatga gagggaaata
     4021 gagaaactcc tttgccaaaa tgcaatagaa aactcctctt ccaaagtagc tgaactgaat
     4081 cgcaaaatcg caactcaaga ggtacttcta aaacatttcc aaggtcaagt taatgagctg
     4141 cagggtaaac aggaatccct tgcagtttct caagttcgag aagaaatcct acagaaacag
     4201 attacaaaac tcttggaaga attgaaagaa gccaaagaaa accacacacc agagatgaag
     4261 catttcatgg gcttagaaag gaagatcaag cagatggaga tgaggcatag gcagagagag
     4321 caggagctcc aacagataat acagcaaaca cgccaagtag tagaaacaga gcaaaacaag
     4381 gaagttgaga aatggaaaag acttgcacag ttaaagaatc gggagctgga caagttccgc
     4441 acagagctgg actccatact ggacgttctg agggagctgc accgacaagg ggttgtggtc
     4501 cccatggctc tcgcaggcga agagaacaca gcagagtttt agtcggaact tggatctgag
     4561 tgaccacatt gtaagacaga tgaaaacctg ctgctgttgg gacaggcacc acacagccat
     4621 gcgtgaccac caccagagta acatatcaga ataaactgcc atgagccaac aggagagaac
     4681 atacatgttg atttatctta ctgaaaacca ttaaacattt gagaaatgag caggttccat
     4741 gacgtcagaa gactgtgact agcaaggtta ctgtgaaagg gctcactccc aggctacagt
     4801 ggaagaggag cgcgcacacc ctcagccaca ctttgtagat taaattattt tgcattttct
     4861 gtcagaccgg aaatcagctc tttctcatga aacagataga tggatgagag cctcgtgctg
     4921 aggacagtct ctgccgcagt ctccaacccg cagagacaag aatgacacag acaccaagag
     4981 gggttcacac agcttcagct tcttttatac ttgcaacttt ttttacttag gacaagggct
     5041 atatttatac agtagcagca actgacctca tcttgctcca caccacctca tccaatcaga
     5101 atcacacaca ctccaggcac gagctcagat cagtcacaga taggctgaca gatccggatc
     5161 acaagaataa tctaacttgg caggcagctt acacatgcag tctcactgtg aatgtccagg
     5221 caaggcagta ataaacatgt gggtttcacg gggcctggca atgggccagg gtgccatctt
     5281 ggcccatgcg gccgc
//
